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目录号:A2004 批次号: A200406
Atezolizumab (anti-PD-L1)是人源、IgG1单克隆抗体,阻止PD-L1与PD-1和B7.1的相互作用,但不影响PD-L2与PD-1的相互作用;MW:145 KD。
CAS号 | 1380723-44-3 |
---|---|
配制 | PBS buffer, pH 7.2 |
推荐同型对照 | Human IgG1 |
来源 | CHO cells |
储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
纯度 | 99% |
蛋白浓度 | 2.9mg/ml |
内毒素 | <1EU/mg |
Favorable impact of PD1/PD-L1 antagonists on bone remodeling: an exploratory prospective clinical study and ex vivo validation [ J Immunother Cancer, 2024, 12(5)e008669] | PubMed: 38702145 |
[ Int Immunopharmacol, 2024, ] | PubMed: 38442580 |
Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker [ J Biol Chem, 2024, S0021-9258(24)01826-X] | PubMed: 38685532 |
Pivotal role of myeloid-derived suppressor cells in infection-related tumor growth [ Cancer Med, 2024, 13(4):e6917] | PubMed: 38457241 |
A novel ultrasensitive chemiluminescence enzyme immunoassay by employment of a signal enhancement of horseradish peroxidase-luminol-hydrogen peroxide reaction for the quantitation of atezolizumab, a monoclonal antibody used for cancer immunotherapy [ RSC Adv, 2024, 14(12):8167-8177] | PubMed: 38469186 |
Acquired resistance to CDK4/6 inhibition is associated with dysregulation of multiple pathways including cyclin D-CDK4/6-RB, EGFR/HER, AKT/mTOR and IFN [ Research Square, 2024, 10.21203/rs.3.rs-3782509/v1] | PubMed: none |
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy [ J Extracell Vesicles, 2023, 12(11):e12379] | PubMed: 37974395 |
YAP1 expression is associated with survival and immunosuppression in small cell lung cancer [ Cell Death Dis, 2023, 14(9):636] | PubMed: 37752152 |
YAP1 expression is associated with survival and immunosuppression in small cell lung cancer [ Cell Death Dis, 2023, 14(9):636] | PubMed: 37752152 |
Synergistically Enhancing Immunotherapy Efficacy in Glioblastoma with Gold-Core Silica-Shell Nanoparticles and Radiation [ Int J Nanomedicine, 2023, 18:7677-7693] | PubMed: 38111846 |
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