Cyclin B2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	Cyclin B2 Rabbit Recombinant mAb detects endogenous level of total Cyclin B2.
背景	Cyclins are the activating partners of a highly conserved family of protein kinases, the cyclin-dependent kinases (CDKs). Cyclin protein family comprises a large number of members. B-type cyclins are synthesized throughout interphase of the cell cycle, but abruptly destroyed at the metaphase-anaphase transition. They function predominantly in M phase. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region.

特异性

Cyclin B2 Rabbit Recombinant mAb detects endogenous level of total Cyclin B2.

背景

Cyclins are the activating partners of a highly conserved family of protein kinases, the cyclin-dependent kinases (CDKs). Cyclin protein family comprises a large number of members. B-type cyclins are synthesized throughout interphase of the cell cycle, but abruptly destroyed at the metaphase-anaphase transition. They function predominantly in M phase. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

45kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Gallant P, et al. J Cell Biol. 1992, 117(1):213-24.

Application Data

WB

Validated by Selleck