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Infliximab (anti-TNF-alpha)
目录号：A2019 批次号: A201901
Infliximab (anti-TNF-alpha)是一种纯化的重组DNA衍生的嵌合人-鼠IgG单克隆抗体，由小鼠重链和轻链可变区与人重链和轻链恒定区组成。Infliximab 通过与可溶性和跨膜形式的TNF-α高亲和力结合而中和 TNF-α 的生物学活性，并抑制或阻止TNF-α与受体的有效结合。MW=144.2 kDa。
抗体信息
| CAS号 | 170277-31-3 |
|---|---|
| 配制 | PBS, pH 7.0 Contains no stabilizers or preservatives |
| 推荐同型对照 | Chimeric IgG1 |
| 来源 | Chimeric (mouse/human) |
| 储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| 除菌 | 0.2 μM filtered |
| 纯度 | 97.9% |
| 蛋白浓度 | 5.00mg/ml |
| 内毒素 | <1EU/mg |
Infliximab (anti-TNF-alpha)在文献中得到引用
| Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies [ Cancer Commun (Lond), 2024, 44(3):408-432] | PubMed: 38407943 |
| Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages [ Nat Commun, 2023, 14(1):3902] | PubMed: 37400454 |
| Human iPSC-Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System [ Small, 2023, e2203725.] | PubMed: 37104853 |
| c-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma [ Front Immunol, 2022, 13:854995] | PubMed: 35359966 |
禁止用于人体及治疗！