pro Caspase 3 Rabbit Recombinant mAb

生物描述

特异性

pro Caspase 3 Rabbit Recombinant mAb detects endogenous level of total pro-Caspase 3.

背景

Pro-caspase-3 is the pro-form of Caspase-3. It is known to reside in the cytoplasm where it remains in an inactive form until it is cleaved by upstream apoptotic caspases. procaspase-3 is capable of autoactivation in vitro. Caspase 8 cleaves procaspases 3, 4, 7, and 9 in vitro. Likewise, caspase 10 cleaves procaspases 3, 7, and 8 in vitro. Caspase 9 can activate caspases 3 and 7. Procaspase 3 is present at high levels in many lymphoid and mature myeloid cells but is present at low levels in breast epithelium and normal neurons.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse
MW (kDa)	35kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Quinn P. Peterson, et al. J Med Chem. 2009, 52(18): 5721-5731. [2] Earnshaw WC, et al. Annu Rev Biochem. 1999, 68:383-424.

Application Data

WB

IHC

IF