| S2849 |
SB269970 HCl |
SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other receptors. |
Selective |
5-HT7, pKi: 8.3 |
| S1283 |
Asenapine |
Asenapine is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder. |
Pan |
5-HT7, pKi: 9.94 |
| S1615 |
Risperidone |
Risperidone is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder. |
Pan |
5-HT7, Ki: 6.6 nM |
| S2677 |
BRL-15572 |
BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor. |
Pan |
5-HT7, pKi: 6.3 |
