| S2473 |
Hexestrol |
Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively. |
Selective |
ERα, EC50: 0.07 nM; ERβ, EC50: 0.175 nM |
| S1598 |
Erteberel (LY500307) |
LY500307 is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2. |
Selective |
ERβ, EC50: 0.66 nM |
| S1191 |
Fulvestrant |
Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM. |
Selective |
ER, IC50: 0.94 nM |
| S1227 |
Raloxifene HCl |
Raloxifene is an estrogen antagonist, which inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM. |
Selective |
ER, IC50: 5.7 nM |
| S2128 |
Bazedoxifene HCl |
Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively. |
Selective |
ERβ, IC50: 89 nM; ERα, IC50: 23 nM |
| S1776 |
Toremifene Citrate |
Toremifene Citrate is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer. |
Selective |
|
| S1238 |
Tamoxifen |
Tamoxifen is an antagonist of the estrogen receptor in breast tissue. |
Selective |
|
| S2450 |
Equol |
Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. Phase 2. |
Selective |
|
| S1709 |
Estradiol |
Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. |
Selective |
|
| S4046 |
Estradiol Cypionate |
Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor. |
Selective |
|
| S1859 |
Diethylstilbestrol |
Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. |
Selective |
|
| S2832 |
Epiandrosterone |
Epiandrosterone is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA. |
Selective |
|
| S2561 |
Clomifene citrate |
Clomifene Citrate is a selective estrogen receptor modulator, used in the treatment of ovulation induction. |
Selective |
|
| S2167 |
Bazedoxifene Acetate |
Bazedoxifene Acetate is a third generation selective estrogen receptor modulator (SERM). |
Selective |
|
| S2466 |
Estriol |
Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. |
Selective |
|
| S4285 |
Ospemifene |
Ospemifene is a non-hormonal selective estrogen receptor modulator (SERM), used for the treatment of dyspareunia.
|
Selective |
|
| S1972 |
Tamoxifen Citrate |
Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding. |
Selective |
|
| S1665 |
Estrone |
Estrone is an estrogenic hormone. |
Selective |
|
| S1625 |
Ethinyl Estradiol |
Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. |
Selective |
|
| S3149 |
Estradiol valerate |
Estradiol is a synthetic ester used to treat menopausal symptoms and hormone deficiencies. |
Selective |
|
