| S1847 |
Clemastine Fumarate |
Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM. |
Selective |
Histamine H1 receptor, IC50: 3 nM |
| S1816 |
Chlorpheniramine Maleate |
Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM. |
Selective |
Histamine H1 receptor, IC50: 12 nM |
| S4026 |
Hydroxyzine 2HCl |
Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [3H]pyrilamine/[3H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM. |
Selective |
Histamine H1 receptor, IC50: 10 nM-19 nM |
| S2107 |
Mizolastine |
Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. |
Selective |
Histamine H1 receptor, IC50: 47 nM |
| S4012 |
Desloratadine |
Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM. |
Selective |
Histamine H1 receptor, IC50: 51 nM |
| S3052 |
Rupatadine Fumarate |
Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively. |
Selective |
Histamine H1 receptor, Ki: 102 nM |
| S3208 |
Fexofenadine HCl |
Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM. |
Selective |
Histamine H1 receptor, IC50: 246 nM |
| S3037 |
Bepotastine Besilate |
Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7. |
Selective |
Histamine H1 receptor, pIC50: 5.7 |
| S1358 |
Loratadine |
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM. |
Selective |
H1 receptor, : ; B(0)AT2, IC50: 4 μM |
| S3146 |
Tripelennamine HCl |
Tripelennamine is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM. |
Selective |
H1 receptor, IC50: 30 μM |
| S4240 |
Doxylamine Succinate |
Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects. |
Selective |
|
| S4262 |
Ebastine |
Ebastine is a potent H1-histamine receptor antagonist, used for allergic disorders. |
Selective |
|
| S1986 |
Meclizine 2HCl |
Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR. |
Selective |
|
| S4008 |
Pemirolast potassium |
Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. |
Selective |
|
| S1866 |
Diphenhydramine HCl |
Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. |
Selective |
|
| S2585 |
Brompheniramine hydrogen maleate |
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist. |
Selective |
|
| S4139 |
Cyclizine 2HCl |
Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity. |
Selective |
|
| S2024 |
Ketotifen Fumarate |
Ketotifen Fumarate is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer. |
Selective |
|
| S4118 |
Histamine 2HCl |
Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2. |
Pan |
|
| S4117 |
Histamine Phosphate |
Histamine acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors. |
Pan |
|
