Abacavir

目录号:S5215 批次号:S521502

打印

化学数据

化学结构式 别名 1592U89 储存条件
(自收到货起)
3年 / -20°C / 粉状
1年 / -80°C / 溶于溶剂
化学式

C14H18N6O

分子量 286.33 CAS号 136470-78-5
Solubility (25°C)* 体外 DMSO 57 mg/mL (199.07 mM)
Ethanol 57 mg/mL (199.07 mM)
Water Insoluble
体内
(现配现用)
均匀悬浊液
CMC-NA
≥5mg/ml 以 1 mL 工作液为例,取 5 mg该产品加到 1 ml CMC-NA 溶液中,混合均匀,即可得工作液浓度为 5 mg/ml的均匀悬浊液。
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述 Abacavir是一种强效核苷类似物逆转录酶抑制剂 (NRTI),用于治疗 HIV 和 AIDS。
靶点
Reverse transcriptase

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

Abacavir在文献中得到引用

Differential Interactome Based Drug Repositioning Unraveled Abacavir, Exemestane, Nortriptyline Hydrochloride, and Tolcapone as Potential Therapeutics for Colorectal Cancers [ Frontiers in Bioinformatics, September 14, 2021, 710591] PubMed: 36303724
The thioacetate-ω(γ-lactam carboxamide) HDAC inhibitor ST7612AA1 as HIV-1 latency reactivation agent [ Antiviral Research, November 2015, 62-69] PubMed: 26348004
Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase [ Antimicrob Agents Chemother, 2023, 67(7):e0046223] PubMed: 37310224
Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase [ Antimicrobial Agents and Chemotherapy, 2023, e00462-23] PubMed: 37310224.0
Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer [ Cancer Discov, 2022, candisc.1117.2021] PubMed: 35320348
Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer [ Cancer Discovery, 2022, 1462-1481] PubMed: 35320348.0
HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy [ Cells, 2021, 10(12)3458] PubMed: 34943964
Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation [ Frontiers in Cardiovascular Medicine, 2021, 634774] PubMed: 33898535
Defining stable reference genes in HIV latency reversal experiments [ J Virol, 2021, JVI.02305-20] PubMed: 33762410
Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation [ Front Cardiovasc Med, 2021, 8:634774] PubMed: 33898535

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品,在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同,大多数建议储存在-20°C,抑制剂属于化学试剂,可在常温下运输储存两周左右。即使如此,我们保证产品的出货量将保持产品质量的条件下,一般都会放入冰袋。望阁下收到产品后,请按照产品数据表建议适当存储。

如果需要长期保存,请于零下二十度低温保存。禁止用于人体及治疗!

退换货政策

Selleck提供宽松的退换货承诺,努力为您营造最优的购物体验。每个订单Selleck只提供一次退换货服务,为了确保您的权益,请您仔细阅读以下内容:

1. 请在返还样品之前事先与我们取得联系,以确保产品是直接向我们或者当地代理商购买的;

2. 自收到货物起七天内,如因运输过程有问题或其他任何问题,您可以提出退换货要求;自收到货物起365天内,如因产品质量有问题,您可以提出退换货要求。

3. 请使用我们的快递账号进行退换货,您无需为此承担任何费用。

4. 如您已收到由Selleck开具的发票,则办理退货或订单金额发生变更的换货时,请将发票随商品一同返还给Selleck。请您妥善保管发票,如发票丢失,将无法办理退换货手续。

5. 对于合理的退换货要求,我们会在5个工作日内处理完成您的款项退还和新换货物的运输等,请耐心等待。