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目录号:A2102 批次号: A210222
克隆号:2.43
Anti-mouse CD8α(克隆号:2.43)可与小鼠CD8α结合反应。CD8是一种穿膜糖蛋白,是T细胞受体(TCR)的协同受体。有助于后续与抗原呈递细胞的交流通讯。
克隆号 | 2.43 |
---|---|
免疫原 | Mouse CTL clone L3 |
配制 | PBS buffer, pH 7.0 |
推荐同型对照 | Rat IgG2b, κ |
应用 | In vivo CD8+ T cell depletion,WB |
储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
除菌 | 0.2 μM filtered |
纯度 | 99% |
蛋白浓度 | 6.39 mg/mL |
内毒素 | <1EU/mg |
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Disulfiram/copper triggers cGAS-STING innate immunity pathway via ROS-induced DNA damage that potentiates antitumor response to PD-1 checkpoint blockade [ Int J Biol Sci, 2025, 21(4):1730-1748] | PubMed: 39990655 |
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cGAS-activated endothelial cell-T cell cross-talk initiates tertiary lymphoid structure formation [ Sci Immunol, 2024, 9(98):eadk2612] | PubMed: 39093956 |
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Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity [ Cell Rep Med, 2024, 5(5):101533] | PubMed: 38744278 |
Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade [ J Immunother Cancer, 2024, 12(9)e009327] | PubMed: 39244215 |
Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer [ Cancer Lett, 2024, 589:216836.] | PubMed: 38556105 |
Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment [ Cell Rep, 2024, 43(9):114697] | PubMed: 39217611 |
HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function [ Cell Oncol (Dordr), 2024, 10.1007/s13402-024-00959-1] | PubMed: 38809326 |
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