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目录号:A2121 批次号: A212109
克隆号:MAR1-5A3
Anti-mouse IFNAR-1-InVivo 单克隆抗体(克隆号:MAR1-5A3)可与 mouse IFNAR-1 (IFN alpha/beta receptor subunit 1)发生反应。Anti-mouse IFNAR-1-InVivo 已被证明可在体外和体内抑制 I 型 IFN 受体信号传导。
| 克隆号 | MAR1-5A3 |
|---|---|
| 免疫原 | Extracellular domain of mouse IFNAR-1 |
| 配制 | PBS Buffer, PH 7.4 |
| 推荐同型对照 | Mouse IgG1, κ |
| 应用 | in vivo IFNAR-1 blockade, in vitro IFNAR-1 blockade, WB |
| 来源 | CHO |
| 小鼠病原体检测 | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| 储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
| 除菌 | 0.2 μM filtered |
| 纯度 | 99% |
| 蛋白浓度 | 6.87 mg/ml |
| 内毒素 | <1EU/mg |


| SBRT embedded in low-dose RT plus αPD-1 (immuno-EclipseRT, iERT) elicits CD8+ T cell immunity against bulky tumors via an IFN-I/NK/DC axis [ Nature Communications, July 8, 2026, 17(1):7568] | PubMed: 42420294 |
| Targeting IFN-I driven tertiary lymphoid structures halts B cell-mediated bone loss in periodontitis [ International Journal of Oral Science, July 27, 2026, 18(1):53] | PubMed: 42503518 |
| Type I IFN Dynamics Define an Early Checkpoint for Survival and Orchestrate Systemic Neutrophil Heterogeneity in Lethal Viral Infection [ nan, January 24, 2026, nan] | |
| Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner [ Cell Reports, January 1, 2023, 42(1):112002] | PubMed: 36662617 |
| Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects [ Cell Communication and Signaling, February 19, 2025, 23(1):99] | PubMed: 39972350 |
| Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition [ Immunity, February 1, 2026, 59(2):458-476.e13] | PubMed: 41619730 |
| sVEGFR1 up-regulation via EGR1 impairs vascular repair in SFTSV-induced hemorrhage [ EMBO Reports, August 11, 2025, 26(18):4477-4502] | PubMed: 40789964 |
| Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone [ Signal Transduction and Targeted Therapy, April 25, 2022, 7(1):137] | PubMed: 35468896 |
| Targeting immune cells in the aged brain with engineered proteins reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition [ Immunity, 2026 Jan 30, 59(2):458–476.e13] | PubMed: 41619730 |
| Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects [ Cell Commun Signal, 2025, 23(1):99] | PubMed: 39972350 |
禁止用于人体及治疗!