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Anti-mouse IL-17A-InVivo
目录号：A2120 批次号: A212008
克隆号：17F3
Anti-mouse IL-17A-InVivo 单克隆抗体 (克隆号:17F3)可与 小鼠 IL-17A发生反应。IL-17A是一种由Th17 细胞、γδ T 细胞、iNKT 细胞、NK 细胞、LTi 细胞、中性粒细胞和肠 Paneth 细胞表达的15-20 kDa 细胞因子。IL-17A 在免疫调节和炎症中具有多效性。Anti-mouse IL-17A-InVivo可在体内中和IL-17A。
抗体信息
| 克隆号 | 17F3 |
|---|---|
| 免疫原 | Mouse IL-17A cross-linked to OVA |
| 配制 | PBS Buffer, PH 7.4 |
| 推荐同型对照 | Mouse IgG1, κ |
| 应用 | in vivo IL-17A neutralization |
| 来源 | CHO |
| 小鼠病原体检测 | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| 储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
| 除菌 | 0.2 μM filtered |
| 纯度 | 99% |
| 蛋白浓度 | 4.75 mg/ml |
| 内毒素 | ＜1EU/mg |
客户使用selleck产品的实验数据
Anti-mouse IL-17A-InVivo在文献中得到引用
| Keratinocyte-specific H4K12 lactylation drives a non-canonical IL-17-dependent signaling in psoriasis progression in mice [ Nature Communications, September 30, 2025, 16(1):8639] | PubMed: 41027887 |
| Cardiac arrest triggers IL-17-mediated neuroinflammation and astrocyte polarization: insights into pathogenesis and intervention [ Journal of Neuroinflammation, November 14, 2025, 22(1):268] | PubMed: 41239323 |
| Analysis and experimental validation of IL-17 pathway and key genes as central roles associated with inflammation in hepatic ischemia-reperfusion injury [ Scientific Reports, March 18, 2024, 14(1):6423] | PubMed: 38494504 |
| Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway [ International Immunopharmacology, March 1, 2024, 129:111614] | PubMed: 38350358 |
| IL-17 Signaling Pathway: A Potential Signaling Pathway Mediating Neuroinflammation Induced by PM 2.5 [ Environment & Health, June 3, 2026, nan] | |
| The IL-17A/Neutrophil axis plays a critical role in lethal infection induced by an emerging ultra-virulent Streptococcus suis serotype 5 strain [ Virulence, June 21, 2026, 17(1)] | PubMed: 42308351 |
| Fungal pathogen-responsive Th17 cells in gut-mouth axis enhance protection against oropharyngeal candidiasis [ iScience, June 1, 2025, 28(6):112675] | PubMed: 40510134 |
| Engineered probiotics platform for oral delivery of antibody as a high-compliance alternative for immune-mediated inflammatory diseases [ Cell Reports Medicine, January 1, 2026, 7(1):102523] | PubMed: 41421354 |
| Immunotherapy-induced sialadenitis: sjögren’s syndrome or a new sialadenitis [ Frontiers in Immunology, February 27, 2026, 17:1755419] | PubMed: 41836391 |
| Th17 cells/IL-17A shape Pasteurella multocida serotype A infection in murine and rabbit models [ Veterinary Research, December 16, 2025, 56(1):229] | PubMed: 41402924 |
禁止用于人体及治疗！