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目录号:A2130 批次号: A213003
克隆号:M17/4
Anti-mouse LFA-1α (CD11a)-InVivo(clone M17/4)是一种单克隆抗体,可与小鼠 LFA-1α(淋巴细胞功能相关抗原 1 α)(也称为整合素 α L 链)发生反应 和CD11a。 它通过与其配体 ICAM-1 (CD54)、 ICAM-2 (CD102) 和 ICAM-3 相互作用,在白细胞细胞间粘附中发挥核心作用 (CD50),并且还在淋巴细胞共刺激信号传导中发挥作用。
| 克隆号 | M17/4 |
|---|---|
| 配制 | PBS, pH 7.0 Contains no stabilizers or preservatives |
| 推荐同型对照 | Rat IgG2a, κ |
| 应用 | Anti-mouse LFA-1α (CD11a)-InVivo |
| 来源 | CHO |
| 小鼠病原体检测 | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| 储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| 除菌 | 0.2 μM filtered |
| 纯度 | 99% |
| 蛋白浓度 | 6.50 mg/ml |
| 内毒素 | <1EU/mg |
| Low-dose radiotherapy synergizes with PD-1 blockade to achieve durable survival in advanced NSCLC through antitumor neutrophil programming [ Signal Transduction and Targeted Therapy, May 7, 2026, 11(1):170] | PubMed: 42091852 |
| Neutralizing LFA-1 alleviates acute lung injury by diminishing pulmonary retention of CAR-T cells [ Pharmacological Research, August 1, 2026, 230:108292] | PubMed: 42285385 |
禁止用于人体及治疗!