APC Human CD62E Antibody [68-5H11]

目录号:H2688

打印

生物描述

特异性
背景 CD62E是一种97-115 kDa的I型跨膜糖蛋白,由SELE基因编码。CD62E也称为E-选择素、内皮-白细胞黏附分子-1(ELAM-1)和白细胞内皮细胞黏附分子2(LECAM-2)。CD62E在未受刺激的内皮细胞上表达极少。活化内皮细胞响应各种激活剂上调表面CD62E表达,包括炎性细胞因子如白细胞介素-1和肿瘤坏死因子。CD62E通过促进炎症期间白细胞在活化内皮细胞上的滚动,在白细胞的血管外渗中发挥作用。

使用信息

抗体应用 FCM 推荐用量 5 uL/million cells in 100 µL volume
反应性 Human
抗体类型 Mouse MW 97-115 kDa
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
储存条件
(自收到货起)
Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Staining HEK-293F cells transfected with pCMV-SELE(human)-3×FLAG-Neo plasmid and fixed/permeabilized with fixation/permeabilization buffer with APC Human CD62E Antibody (Clone: 68-5H11) (Product Number: H2688) (green, red is unstained control). Analysis was performed on total cells.