APC Human LOX-1 Antibody [15C4]

目录号:H3903

打印

生物描述

特异性
背景 凝集素样氧化低密度脂蛋白受体1(LOX-1),也称为CLEC8A,是一种31 kDa的单次II型跨膜蛋白,是C型凝集素超家族的成员。LOX-1是一种清道夫受体,参与内吞作用、吞噬作用和细胞因子产生。CLEC8A由内皮细胞、平滑肌细胞、血小板、成纤维细胞和巨噬细胞表达,并在炎症和氧化刺激下上调。LOX-1识别多种配体,包括脂蛋白、凋亡细胞、热休克蛋白、C反应蛋白和氧化LDL。LOX-1与动脉粥样硬化和血管炎症有关。

使用信息

抗体应用 FCM 推荐用量 5 uL/million cells in 100 µL volume
反应性 Human
抗体类型 Mouse MW 31 kDa
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
储存条件
(自收到货起)
Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Staining HEK-293F cells transfected with pCMV-OLR1(human)-3×FLAG-Neo plasmid and fixed/permeabilized with fixation/permeabilization buffer with APC Human LOX-1 Antibody (Clone: 15C4) (Product Number: H3903) (green, red is unstained control). Analysis was performed on total cells.