Chlorpromazine

目录号：S5749 批次号：S574904

化学数据

	别名	CPZ	储存条件 (自收到货起)	3年 -20°C 粉状
	化学式	C₁₇H₁₉ClN₂S
	分子量	318.86	CAS号	50-53-3
Solubility (25°C)*	体外	DMSO	65 mg/mL (203.85 mM)
		Ethanol	64 mg/mL (200.71 mM)
		Water	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述	Chlorpromazine (CPZ) 是一种低效的典型抗精神病药，用于治疗精神病如精神分裂症。Chlorpromazine (CPZ) 在体外可抑制 5-HT(2A) receptor 和 dopamine D2。Chlorpromazine (CPZ) 还可抑制 sodium channel，并阻断HERG potassium channels，对应的IC50值为21.6 μM。

参考文献

Chlorpromazine在文献中得到引用

Gonococcal OMV-delivered PorB induces epithelial cell mitophagy [ Nat Commun, 2024, 15(1):1669]	PubMed: 38396029
Proton pump inhibitors enhance macropinocytosis-mediated extracellular vesicle endocytosis by inducing membrane v-ATPase assembly [ J Extracell Vesicles, 2024, 13(4):e12426]	PubMed: 38532609
Proton pump inhibitors enhance macropinocytosis-mediated extracellular vesicle endocytosis by inducing membrane v-ATPase assembly [ J Extracell Vesicles, 2024, 13(4):e12426]	PubMed: 38532609
Extracellular Vesicle Spherical Nucleic Acids [ JACS Au, 2024, 4(6):2381-2392]	PubMed: 38938802
The combination therapy using tyrosine kinase receptors inhibitors and repurposed drugs to target patient-derived glioblastoma stem cells [ Biomed Pharmacother, 2024, 176:116892]	PubMed: 38876048
Real-Time Dissection of the Transportation and miRNA-Release Dynamics of Small Extracellular Vesicles [ Adv Sci (Weinh), 2023, 10(7):e2205566]	PubMed: 36599707
Treatment of Ulcerative Colitis by Cationic Liposome Delivered NLRP3 siRNA [ Int J Nanomedicine, 2023, 18:4647-4662]	PubMed: 37605735
Porcine deltacoronavirus enters ST cells by clathrin-mediated endocytosis and does not require Rab5, Rab7, or Rab11 [ Microbiol Spectr, 2023, 10.1128/spectrum.02553-23]	PubMed: 37962380
Evaluation of the liver targeting and anti‑liver cancer activity of artesunate‑loaded and glycyrrhetinic acid‑coated nanoparticles [ Exp Ther Med, 2023, 26(5):516]	PubMed: 37854499
Evaluation of the liver targeting and anti‑liver cancer activity of artesunate‑loaded and glycyrrhetinic acid‑coated nanoparticles [ Exp Ther Med, 2023, 26(5):516]	PubMed: 37854499

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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