Lipopolysaccharides (LPS)

目录号：S7850 批次号：S785002

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化学数据

化学结构式 别名 LPSs, Endotoxin,LPS 储存条件
(自收到货起)		 3年 -20°C 粉状
化学式
分子量 CAS号 93572-42-0
Solubility (25°C)* 体外 Water 15 mg/mL
DMSO Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

生物活性

产品描述 Lipopolysaccharides (LPSs, Endotoxin,LPS) 是一种内毒素，来源于革兰氏阴性菌外膜的小叶，由苯酚纯化制得。Lipopolysaccharides由抗原 O 特异性链、核心寡糖和脂质 A 组成。Lipopolysaccharides是一种激活免疫系统的致病相关分子模式 (pathogenic associated molecular pattern, PAMP)。 Lipopolysaccharides能够激活免疫细胞上的 TLR-4，还能诱导细胞迁移体的分泌。

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

Lipopolysaccharides (LPS)在文献中得到引用

Unveiling the mechanisms of CEBPD-orchestrated TAM polarization through RGS2/PAR2 pathway and its impact on ICB efficacy in clear cell renal cell carcinoma [ J Immunother Cancer, 2025, 13(7)e010898] PubMed: 40659446
Loss of neurofibromin induces inflammatory macrophage phenotypic switch and retinal neovascularization via GLUT1 activation [ Cell Rep, 2025, 44(5):115625] PubMed: 40279245
Targeting RPLP2 Triggers DLBCL Ferroptosis by Decreasing FXN Expression [ Biomedicines, 2025, 13(6)1320] PubMed: 40564039
GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC [ Mediators Inflamm, 2025, 2025:5576056] PubMed: 40862294
New insights into DEHP-induced inflammatory injury in chicken spleen: ROS/TLR4/MyD88 pathway and apoptosis/necroptosis-M1 polarization crosstalk [ Poult Sci, 2025, 104(6):105074] PubMed: 40245538
Transcription factor Yy1 modulates Trem1 to control LPS-triggered neuroinflammation and oxidative stress in mouse astrocytes via the NF-κB pathway [ Gen Physiol Biophys, 2025, 44(1):81-92] PubMed: 39815902
Small nuclear ribonucleoprotein polypeptide B2 regulated by SNHG4/miR-204-5p axis inhibits ferroptosis to aggravate the progression of hepatocellular carcinoma [ Discov Oncol, 2025, 16(1):1349] PubMed: 40670855
Azithromycin regulates Mettl3-mediated NF-κB pathway to enhance M2 polarization of RAW264.7 macrophages and attenuate LPS-triggered cytotoxicity of MLE-12 alveolar cells [ Int Immunopharmacol, 2024, 137:112426] PubMed: 38878491
Lumbrokinase Extracted from Earthworms Synergizes with Bevacizumab and Chemotherapeutics in Treating Non-Small Cell Lung Cancer by Targeted Inactivation of BPTF/VEGF and NF-κB/COX-2 Signaling [ Biomolecules, 2024, 14(7)741] PubMed: 39062456
Identification of subclusters and prognostic genes based on GLS-associated molecular signature in ulcerative colitis [ Sci Rep, 2024, 14(1):13102] PubMed: 38849409

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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