LMO2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	LMO2 Rabbit Recombinant mAb detects endogenous level of total LMO2.
背景	The LIM-only protein 2 (LMO2) is an essential transcriptional regulator in hematopoiesis, whose inappropriate regulation frequently contributes to the development of leukemia. LMO2 belongs to a subset of the large zinc finger protein family, the LMO proteins. LMO2 is also a key regulator of angiogenesis, where it has a specific role in the remodeling of the existing capillary network into mature vasculature. LMO2 is expressed in a range of tissues during development but not in normal mature thymocytes other than tumourigenic T cells. LMO2 does not bind DNA directly but instead acts by forming part of a bridge for DNA-binding proteins to create a bipartite multi-protein DNA-binding complex. LMO2 has a flexible multi-protein complex nucleation function in different cell settings.

特异性

LMO2 Rabbit Recombinant mAb detects endogenous level of total LMO2.

背景

The LIM-only protein 2 (LMO2) is an essential transcriptional regulator in hematopoiesis, whose inappropriate regulation frequently contributes to the development of leukemia. LMO2 belongs to a subset of the large zinc finger protein family, the LMO proteins. LMO2 is also a key regulator of angiogenesis, where it has a specific role in the remodeling of the existing capillary network into mature vasculature. LMO2 is expressed in a range of tissues during development but not in normal mature thymocytes other than tumourigenic T cells. LMO2 does not bind DNA directly but instead acts by forming part of a bridge for DNA-binding proteins to create a bipartite multi-protein DNA-binding complex. LMO2 has a flexible multi-protein complex nucleation function in different cell settings.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

18kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck