Ramucirumab (anti-VEGFR2)

目录号：A2003         批次号: A200302

打印

Ramucirumab (anti-VEGFR2) 是IgG1类的单克隆抗体，可与 VEGF-R2 结合并阻止其激活，其阻断KDR与VEGF结合的 IC50 值为0.8 nM；MW: 143.6 KD。

抗体信息

CAS号 947687-13-0
配制 PBS buffer, pH 7.2
推荐同型对照 human IgG1
储存条件
(自收到货起)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
除菌 0.2 μM filtered
纯度 99%
蛋白浓度 8.288mg/ml
内毒素 ＜1EU/mg

Ramucirumab (anti-VEGFR2)在文献中得到引用

ALK5/VEGFR2 dual inhibitor TU2218 alone or in combination with immune checkpoint inhibitors enhances immune-mediated antitumor effects [ Cancer Immunol Immunother, 2024, 73(10):190] PubMed: 39105882
[ Int J Mol Sci, 2024, ] PubMed: 38339049
Comparison of Tepotinib, Paclitaxel, or Ramucirumab Efficacy According to the Copy Number or Phosphorylation Status of the MET Gene: Doublet Treatment versus Single Agent Treatment [ Int J Mol Sci, 2024, 25(3)1769] PubMed: 38339049
Analysis of Tumor Heterogeneity Through AXL Activation in Primary Resistance to EGFR Tyrosine Kinase Inhibitors [ JTO Clin Res Rep, 2023, 4(6):100525] PubMed: 37426308
Analysis of Tumor Heterogeneity Through AXL Activation in Primary Resistance to EGFR Tyrosine Kinase Inhibitors [ JTO Clin Res Rep, 2023, 4(6):100525] PubMed: 37426308

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