TLR2-IN-C29

目录号：S6597 批次号：S659704

打印

化学数据

别名

C29

储存条件
(自收到货起)

3年 -20°C 粉状

化学式

C₁₆H₁₅NO₄

分子量

285.29

CAS号

363600-92-4

Solubility (25°C)*

体外

DMSO

57 mg/mL (199.79 mM)

Water

Insoluble

Ethanol

Insoluble

体内
（现配现用）

均匀悬浊液

CMC-NA

≥5mg/ml

以 1 mL 工作液为例，取 5 mg该产品加到 1 ml CMC-NA 溶液中，混合均匀，即可得工作液浓度为 5 mg/ml的均匀悬浊液。

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述

TLR2-IN-C29 (C29)是一种 Toll-like receptor 2 (TLR2) 的抑制剂，可抑制TLR2/1和TLR2/6的信号传导。

靶点

TLR2

参考文献

TLR2-IN-C29在文献中得到引用

Neutrophil extracellular traps license macrophage production of chemokines to facilitate CD8+ T cell infiltration in obstruction-induced renal fibrosis [ Protein Cell, 2025, pwaf020]	PubMed: 39998389
α-Synuclein orchestrates Th17 responses as antigen and adjuvant in Parkinson's disease [ J Neuroinflammation, 2025, 22(1):38]	PubMed: 39934862
Direct activation of Toll-like receptor 2 signaling stimulated by contact with the interfacial structures of chitin nanofibers [ Int J Biol Macromol, 2025, 284(Pt 2):138092]	PubMed: 39613079
Gusongan capsule enhances osteogenic differentiation to mitigate bone loss in ovariectomized rats via the TLR2/NF-κB pathway [ Phytomedicine, 2025, 141:156705]	PubMed: 40215821
Streptococcus pyogenes EVs induce the alternative inflammasome via caspase-4/-5 in human monocytes [ EMBO Rep, 2025, 10.1038/s44319-025-00558-7]	PubMed: 40925957
Mitochondrial ROS-ER Stress Axis Governs IL-10 Production in Neutrophils and Regulates Inflammation in Murine Chlamydia pneumoniae Lung Infection [ Cells, 2025, 14(19)1523]	PubMed: 41090752
The immune response against cancer is modulated by stromal cell fibronectin [ Neoplasia, 2025, 67:101196]	PubMed: 40592236
Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway [ BMC Complement Med Ther, 2025, 25(1):222]	PubMed: 40604913
Pentatrichomonas hominis induces extracellular traps formation of macrophages via the TLR2/NADPH/PAD4 pathway [ Parasit Vectors, 2025, 18(1):248]	PubMed: 40598534
A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy [ Nat Commun, 2024, 15(1):10726]	PubMed: 39730328

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

退换货政策

Selleck提供宽松的退换货承诺，努力为您营造最优的购物体验。每个订单Selleck只提供一次退换货服务，为了确保您的权益，请您仔细阅读以下内容：

1. 请在返还样品之前事先与我们取得联系，以确保产品是直接向我们或者当地代理商购买的；

2. 自收到货物起七天内，如因运输过程有问题或其他任何问题，您可以提出退换货要求；自收到货物起365天内，如因产品质量有问题，您可以提出退换货要求。

3. 请使用我们的快递账号进行退换货，您无需为此承担任何费用。

4. 如您已收到由Selleck开具的发票，则办理退货或订单金额发生变更的换货时，请将发票随商品一同返还给Selleck。请您妥善保管发票，如发票丢失，将无法办理退换货手续。