Tocilizumab (anti-IL-6R)

目录号：A2012         批次号: A201203

打印

Tocilizumab (anti-human IL-6R)是人源单克隆单体，可与interleukin-6 receptor结合发挥抑制作用。MW: 148 KD。

抗体信息

CAS号 ‎375823-41-9
配制 PBS buffer, pH 7.2
推荐同型对照 Human IgG1
来源 CHO cells
储存条件
(自收到货起)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
除菌 0.2 μM filtered
纯度 98.4%
蛋白浓度 5 mg/ml
内毒素 <1 EU/mg

Tocilizumab (anti-IL-6R)在文献中得到引用

FTO SUMOylation regulates the differentiation of bone marrow mesenchymal stromal cells in inflammatory bowel disease-induced bone loss [ Cell Rep, 2025, 44(7):115953] PubMed: 40616843
Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis [ Cell Rep, 2025, 44(2):115287] PubMed: 40009514
HSP27/IL-6 axis promotes OSCC chemoresistance, invasion and migration by orchestrating macrophages via a positive feedback loop [ Cell Biol Toxicol, 2025, 41(1):36] PubMed: 39873845
Cells in the Polyaneuploid Cancer Cell State Are Prometastatic [ Mol Cancer Res, 2025, 23(3):219-235] PubMed: 39656186
Targeting Fibroblast-Derived Interleukin 6: A Strategy to Overcome Epithelial-Mesenchymal Transition and Radioresistance in Head and Neck Cancer [ Cancers (Basel), 2025, 17(2)267] PubMed: 39858048
IL-6-Caspase 3 Axis Plays an Important Role in Enteritis Caused by Legionella pneumophila Pulmonary Infection [ Microorganisms, 2025, 13(2)313] PubMed: 40005679
Targeting RPE Senescence Via Suppressing IL-6/IL-6R Signaling for Treating Retinal Degenerative Diseases [ Invest Ophthalmol Vis Sci, 2025, 66(12):44] PubMed: 40970669
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution [ Nature, 2024, 10.1038/s41586-024-08031-6] PubMed: 39385030
Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells [ Cell Rep Med, 2024, S2666-3791(24)00195-2] PubMed: 38670095
CALB2 drives pancreatic cancer metastasis through inflammatory reprogramming of the tumor microenvironment [ J Exp Clin Cancer Res, 2024, 43(1):277] PubMed: 39358777

禁止用于人体及治疗！