| S1271 |
Acarbose
|
Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) 是一种肠道alpha-glucosidase抑制剂，用于治疗II型糖尿病。 |
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Infect Genet Evol, 2020, 81:104210
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| S9215 |
Pinoresinol diglucoside
|
Pinoresinol diglucoside, one of the major lignans isolated from Eucommia ulmoides Oliver bark, has various pharmacological functions, including antihypertension and prevention of osteoporosis. |
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Molecules-, 2021, 26(4)
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| S3839 |
1-Deoxynojirimycin
|
1-Deoxynojirimycin (duvoglustat, moranolin) is a potent α-glucosidase inhibitor and most commonly found in mulberry leaves. It has therapeutic potency against diabetes mellitus. |
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J Biol Chem, 2022, 298(12):102643
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| S1024 |
LTI-291
|
LTI-291是第一个用于治疗帕金森病的Glucocerebrosidase(GCase)小分子激活剂。 |
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Exp Mol Med, 2022, 54-9:1536-1548
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| S4101 |
Voglibose
|
Voglibose (AO 128) 是一种N取代的井岗霉醇胺衍生物，对α葡糖苷酶具有优异的抑制活性，也具有抗高血糖症和由高血糖症引起的各种疾病的作用。
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G3 (Bethesda), 2020, 4;10(5):1585-1597
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| E7012 |
Conduritol B epoxide
|
Conduritol B epoxide 是不可逆共价的Gcase抑制剂。 |
|
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| E0477 |
N-Caffeoyl O-methyltyramine
|
N-Caffeoyl O-methyltyramine是从Cuscuta reflexa中分离得到的一种生物碱，对α-葡萄糖苷酶（α-glucosidase）具有较强的抑制活性，IC50为103.58 μM。 |
|
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| S6493 |
n-Butylidenephthalide
|
n-Butylidenephthalide ((Z)-Butylidenephthalide, 3-Butylidenephthalide, Butylidenephthalide) 可从当归的氯仿提取物中分离出来，它具有多种生物活性，如减少心绞痛、血小板聚集、增殖、非特异性痉挛。 |
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| S0553 |
Butyl isobutyl phthalate
|
Butyl isobutyl phthalate (BIP) 是一种从 Laminaria japonica 的根状茎中分离出来的，α-glucosidase 的非竞争性抑制剂，其IC50值为38 μM。Butyl isobutyl phthalate 具有显著的降血糖作用和治疗糖尿病的潜力。 |
|
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| S5331 |
Ceftezole sodium
|
Ceftezole Sodium (Celoslin sodium, Falomesin sodium) is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity. |
|
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| E7646 |
Castanospermine
|
Castanospermine 是一种天然生物碱，可从黑豆或莫顿湾栗树 (Castanospermum australae) 中提取。Castanospermine 是 α/β -葡萄糖苷酶抑制剂。 Castanospermine 有抗炎、抗病毒复制和抗前列腺癌转移作用。Castanospermine 可作为预防移植排斥反应的免疫抑制剂。 |
|
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| S9378 |
4',5-Dihydroxyflavone
|
4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase. |
-
Medical University of Bialystok, 2022, Vol. 79 No. 6 pp. 835-840, 2022
|
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| E7126 |
Licochalcone C
|
Licochalcone C 能够抑制 α-葡萄糖苷酶 (α-glucosidase)，其对 α-葡萄糖苷酶和蛋白酪氨酸磷酸酶 1B 的 IC50 值分别为 <100 nM 和 92.43 μM。 |
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| S3796 |
Rebaudioside A
|
Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. |
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| S9445 |
Ginkgolic Acid (C13:0)
|
Ginkgolic Acid (C13:0) 是银杏中的一种天然抗龋剂，对变形链球菌(S. mutans)具有抗菌活性，并能抑制与其致龋性相关的特定毒力因子。银杏酸是一种有效的 sumoylation 抑制剂，据报道可抑制 histone acetylation transferase (HAT) 。 |
|
|
| S4101 |
Voglibose
|
Voglibose (AO 128) 是一种N取代的井岗霉醇胺衍生物，对α葡糖苷酶具有优异的抑制活性，也具有抗高血糖症和由高血糖症引起的各种疾病的作用。
|
- G3 (Bethesda), 2020, 4;10(5):1585-1597
|
|
| E7012 |
Conduritol B epoxide
|
Conduritol B epoxide 是不可逆共价的Gcase抑制剂。 |
|
|
| E0477 |
N-Caffeoyl O-methyltyramine
|
N-Caffeoyl O-methyltyramine是从Cuscuta reflexa中分离得到的一种生物碱，对α-葡萄糖苷酶（α-glucosidase）具有较强的抑制活性，IC50为103.58 μM。 |
|
|
| S0553 |
Butyl isobutyl phthalate
|
Butyl isobutyl phthalate (BIP) 是一种从 Laminaria japonica 的根状茎中分离出来的，α-glucosidase 的非竞争性抑制剂，其IC50值为38 μM。Butyl isobutyl phthalate 具有显著的降血糖作用和治疗糖尿病的潜力。 |
|
|
| E7646 |
Castanospermine
|
Castanospermine 是一种天然生物碱，可从黑豆或莫顿湾栗树 (Castanospermum australae) 中提取。Castanospermine 是 α/β -葡萄糖苷酶抑制剂。 Castanospermine 有抗炎、抗病毒复制和抗前列腺癌转移作用。Castanospermine 可作为预防移植排斥反应的免疫抑制剂。 |
|
|
| S9378 |
4',5-Dihydroxyflavone
|
4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase. |
- Medical University of Bialystok, 2022, Vol. 79 No. 6 pp. 835-840, 2022
|
|
| S3796 |
Rebaudioside A
|
Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. |
|
|
| S9445 |
Ginkgolic Acid (C13:0)
|
Ginkgolic Acid (C13:0) 是银杏中的一种天然抗龋剂，对变形链球菌(S. mutans)具有抗菌活性，并能抑制与其致龋性相关的特定毒力因子。银杏酸是一种有效的 sumoylation 抑制剂，据报道可抑制 histone acetylation transferase (HAT) 。 |
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