天然产物

天然产物库3048种天然产物的独特集合,可用于高通量筛选和高内涵筛选。
目录号 产品名 产品描述
E2918 Sesame Oil Sesame oil是一种具有抗炎和抗氧化特性的补充剂,可有效减少动脉粥样硬化和心血管疾病的风险。
E2759 L-(+)-Ergothioneine L-(+)-Ergothioneine(Ergothioneine)是组氨酸甜菜碱的咪唑-2-硫酮衍生物,由某些细菌和真菌合成。 Ergothioneine通常被认为是一种抗氧化剂。
E2862 (+/-)-Naringenin (±)-Naringenin 是柑橘类水果中存在的一种天然类黄酮,可诱导癌细胞凋亡和细胞毒性。
E2863 Garcinia cambogia extract Garcinia cambogia extract具有降胆固醇作用,可用于治疗肥胖症。 (-)-hydroxycitrate (HCA) 是标准化 Garcinia cambogia 提取物的主要化合物,是 ATP-柠檬酸裂解酶的竞争性抑制剂。
E2530 Isofebrifugin Isofebrifugine是一种天然的喹唑啉酮生物碱,具有抗疟作用。
E2411 Taurodeoxycholic acid sodium hydrate Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate),一种胆汁酸,是一种由肝脏中的胆固醇合成的两亲性表面活性剂分子。 除了 TGR5 通路外,它还激活 S1PR2 通路。
E2430 Allocholic acid Allocholic acid 是一种典型的胎儿胆汁酸,存在于脊椎动物中,并在肝再生和癌变过程中重新出现。 Allocholic acid 也是成人嗅觉系统的有效和特异性兴奋剂。
E2459 Ginsenoside Rg5 Ginsenoside Rg5是红参的主要成分,可阻断IGF-1与其受体的结合,IC50约为90 nM。 人参皂苷 Rg5 还通过抑制NF-κB p65的DNA结合活性来抑制COX-2的mRNA表达。
E2017 Deoxypodophyllotoxin Deoxypodophyllotoxin (DPT)是鬼臼毒素的衍生物,是一种来自Anthriscus sylvestris的木质素,具有有效的抗有丝分裂、抗炎和抗病毒活性。
E0701 Cucurbitacin D Cucurbitacin D是Cucurbita texana中的一种活性成分,可破坏HSP90的成熟以及Hsp90与两个辅助伴侣分子Cdc37和p23之间的相互作用。
S0915 Morusin Morusin (Mulberrochromene)是NF-κB和STAT3的抑制剂。Morusin是一种从Marsdenia australis中分离出来的异戊烯化黄酮类化合物,具有抗肿瘤、抗氧化和抗菌特性。
E0752 Paederoside Paederoside是一种从Paederia pertomentosa中分离出来的单萜 S-甲基硫代碳酸酯,可抑制Epstein-Barr病毒(EBV)早期抗原(EA)
E2226 4-Hydroxyderricin 4-Hydroxyderricin(4-HD)是当归Angelica keiskei的主要活性成分,是一种有效的选择性单胺氧化酶 (monoamine oxidase, MAO)抑制剂,对 多巴胺 β-羟化酶(dopamine β-hydroxylase, DBH)具有轻微的抑制作用。
E2231 Xanthoangelol Xanthoangelol是一种存在于当归Angelica keiskei根部的查尔酮,是一种非选择性的单胺氧化酶(monoamine oxidase, MAO) 抑制剂和有效的 多巴胺 β-羟化酶 (dopamine β-hydroxylase, DBH)抑制剂。它具有抗炎、抗菌和促凋亡活性。
E2237 Vasicine (hydrochloride) Vasicine hydrochloride(Peganine hydrochloride)是一种从Adhatoda vasica中分离出来的生物碱vasicine (VAS)的盐,是一种潜在的天然胆碱酯酶抑制剂。VAS抑制乙酰胆碱酯酶(AChE)和丁酰胆碱酯酶(BChE)。
E2484 Hydrastine Hydrastine ((-)-β-Hydrastine; (1R,9S)-β-Hydrastine)是一种存在于Hydrastis canadensis中的天然生物碱,是PAK4 的抑制剂。
E0700 cucurbitacin E Cucurbitacin E (α-Elaterin; α-Elaterine)是一种来源于Cucumic melo L.的四环三萜,是JAK2 和 STAT3的抑制剂。
E2286 Dihydrolanosterol Dihydrolanosterol (24,25-Dihydrolanosterol; Dihydrolanosterin; Lanostenol)通过促进HMG CoA还原酶的泛素化和降解来抑制胆固醇的生物合成。
E2502 Tamarixetin Tamarixetin (4'-O-Methyl Quercetin)是槲皮素的天然类黄酮衍生物,由于增加分泌 IL-10 的免疫细胞数量,在细菌性败血症中具有优异的抗炎特性。
S0922 Salvianolic acid C Salvianolic acid C是一种非竞争性的细胞色素P4502C8 (Cytochrome P4502C8, CYP2C8)抑制剂和细胞色素P45022J2(Cytochrome P45022J2, CYP2J2)的中度混合抑制剂。
E0250 Artemitin Artemitin是一种黄酮醇,存在于Laggera pterodonta (DC.) Benth.中,具有抗氧化、抗炎和抗病毒活性。
S3243 Zeaxanthin Zeaxanthin是一种类胡萝卜素醇,参与叶黄素循环,激活外在凋亡途径,诱导葡萄膜黑色素瘤细胞凋亡,IC50 值为40.8 µM。
E3540 Grapefruit Extract Grapefruit Extract是从葡萄柚Citrus paradisi Macf.中提取的,可在肠道内作为免疫调节剂,维持肠道巨噬细胞稳态。
E3319 Grifola frondosa Extract Grifola Frondosa Extract从灰树花Grifola Frondosa中提取,具有抗肿瘤、免疫调节、抗糖尿病、抗高脂血症和抗病毒活性。
E2748 EGCG Octaacetate EGCG Octaacetate(AcEGCG)是表没食子儿茶素-3-没食子酸酯 (epigallocatechin-3-gallate, EGCG) 的前药。EGCG具有抗氧化、抗有丝分裂和抗血管生成特性。
E2438 Ginsenoside Rg3 Ginsenoside Rg3是一种存在于人参(Panax ginseng)和三七(Panax japonicus var.)中的人参皂苷,主要用于肿瘤疾病的研究。
E3570 Artemisia annua Extract Artemisia Annua Extract是从黄花蒿Artemisia Annua中提取的,具有抗疟、抗癌作用。
E0657 Rubiadin 1-methyl ether Rubiadin-1-methyl ethe是一种从巴戟天(Morinda officinalis How)根中分离得到的天然蒽醌类化合物,可通过阻断NF-κB通路抑制破骨细胞的骨吸收,有望成为预防和治疗过度骨吸收导致的骨病的药物。
E2693 Phycocyanobilin (PCB) Phycocyanobilin (PCB)是一种开链四吡咯发色团,共价键合到 C-藻蓝蛋白(C-Phycocyanin, C-PC)的两条多肽链上,C-藻蓝蛋白是螺旋藻(Spirulina platensis)中最具代表性的胆蛋白。其保护细胞的机制包括减少氧化应激损伤,这可能有助于其治疗神经退行性疾病的临床疗效。此产品溶解度不佳,动物实验可用,细胞实验请谨慎选择!
S8989 Xanthatin Xanthatin是一种从中药苍耳(Xanthium strumarium)叶子中分离得到的倍半萜内酯,可抑制核因子kappa-B (nuclear factor kappa-B, NF-κB)、丝裂原活化蛋白激酶(mitogen-activated protein kinase, MAPK)以及信号转导和转录激活因子(signal transducer and activator of transcription, STATs)信号通路
E0599 Arecaidine hydrochloride Arecaidine hydrochloride是槟榔果(Areca catechu)的一种成分,可抑制GABA和β-丙氨酸的吸收,但不抑制甘氨酸的吸收。
S0563 10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyl paclitaxel (10-Deacetyl-7-xylosyltaxol, 7-xylosyl-10-deacetylpaclitaxel)是紫杉醇的衍生物,也是天然存在的木糖苷,从Taxus chinensis中分离出来,它可以引起PC-3细胞明显的有丝分裂停滞,并上调促凋亡蛋白Bax和Bad的表达,以及下调抗凋亡蛋白Bcl-2和Bcl-XL的表达,从而导致线粒体膜通透性的紊乱和caspase-9的激活。
E3387 Sophora flavescens Extract Sophora Flavescens Extract从苦参Sophora flavescens中提取,用于治疗溃疡性结肠炎湿热积证。
E1138 CQ31 CQ31是一种小分子,可选择性地激活半胱天冬酶活化和募集结构域8 (caspase activation and recruitment domain-containing 8, CARD8)
E3682 Pseudostellaria heterophylla Extract Pseudostellaria Heterophylla Extract是从太子参Pseudostellaria Heterophylla中提取的,具有抗肿瘤作用。
E0769 Ginsenoside Rh4 Ginsenoside Rh4是中药人参的重要有效成分,已被证明能够抑制Wnt/β-Catenin、JAK2/STAT3、TGF-β/Smad2/3等信号通路。
E2683 Ursodeoxycholic acid sodium Ursodeoxycholic acid sodium是一种天然胆汁酸的钠盐,用于治疗多种肝脏和胃肠道疾病。
E0671 Deacetylasperulosidic acid Deacetylasperulosidic acid是Morinda citrifolia果实的主要植物化学成分,具有提高超氧化物歧化酶(superoxide dismutase, SOD)活性的抗氧化活性,以及抑制诱导仓鼠卵巢细胞和小鼠染色体畸变的抗致裂活性。
S8233 Prodigiosin Prodigiosin是一种由多种细菌产生的天然红色素,可抑制Wnt/β-catenin信号通路
S6975 N-Vanillyldecanamide N-Vanillyldecanamide是一种从辣椒(Capsicum annuum)果实中分离得到的辣椒素,能以剂量依赖性方式显著降低莴苣(Lactuca sativa)幼苗的自由基长度。
E3199 Petasites Japonicus Extract Petasites Japonicus Extract从蜂斗菜Petasites Japonicus中提取,用于治疗偏头痛和紧张性头痛。
E0758 Silydianin Silydianin是Silybium marianum的活性成分,具有抗胶原酶、抗肿瘤和抗弹性蛋白酶等活性,Silydianin也是一种天然蛋白酪氨酸磷酸酶1B (protein tyrosine phosphatase 1B, PTP1B)抑制剂,IC50为17.38 μM。
E2548 N-(p-Coumaroyl) Serotonin N-(p-Coumaroyl) Serotonin (p-coumaroylserotonin)是一种从红花种子中分离出来的多酚,具有抗氧化、抗动脉粥样硬化和抗炎作用,能够抑制PDGF诱导的PDGF受体磷酸化和肌浆网Ca2+释放。
E2274 Hexahydrocurcumin Hexahydrocurcumin是姜黄素的主要代谢物之一,是一种选择性的、可口服的活性COX-2抑制剂,具有抗氧化、抗癌、抗炎等活性。
E0477 N-Caffeoyl O-methyltyramine N-Caffeoyl O-methyltyramine是从Cuscuta reflexa中分离得到的一种生物碱,对α-葡萄糖苷酶(α-glucosidase)具有较强的抑制活性,IC50为103.58 μM。
E2833 1,5-Anhydro-D-glucitol 1,5-Anhydro-D-glucitol (1,5-Anhydroglucitol, 1,5-AG)是一种天然存在的单糖,普遍存在于几乎所有的食物中,可为糖尿病(diabetes mellitus, DM)的早期预测和早期筛查提供可靠的依据。
E2354 Valepotriate Valepotriate从Valeriana jatamansi Jones中分离一种不稳定的环烯醚萜,通过显著增加GABAA、谷氨酸脱羧酶65 (glutamic acid decarboxylase 65)和Bcl-2的表达,以及降低caspase-3表达发挥抗癫痫作用。
E2641 trans-Chalcone Trans-Chalcone是类黄酮的主干,也是一种有效的脂肪酸合酶(fatty acid synthase, FAS)IC50为17.1 μg/mL,以及α-淀粉酶(α-amylase)抑制剂,可引起乳腺癌细胞系MCF-7的细胞周期阻滞并诱导细胞凋亡,发挥抗真菌和抗癌活性。
E0738 Gipsoside Gypenoside是一种来自gypsophila paniculata L.的三萜皂苷。
E0831 Pseudocoptisine chloride Pseudocoptisine chloride (Isocoptisine chloride)是一种分离自Corydalis Tuber具有苄基异喹啉骨架的季生物碱,抑制乙酰胆碱酯酶(acetylcholinesterase, AChE)活性,IC50为12.8 μM,具有抗炎和抗健忘的作用。
E3505 Hibiscus syriacus flower Extract Hibiscus syriacus flower Extract是从木槿Hibiscus syriacus的花中提取的,其中含有有助于皮肤再生和保湿的化合物。
E3503 Papaya Leaf Extract Papaya Leaf Extract是从番木瓜Carica papaya的叶子中提取的,具有抗癌、抗炎、抗糖尿病和抗病毒活性。
E3684 Semen Persicae Extract Semen Persicae Extract是从桃仁Semen Persicae中提取的。
E3685 Ampelopsis grossedentata Extract Ampelopsis Grossedentata Extract提取自藤茶Ampelopsi Grossedentata,可诱导癌细胞凋亡。
E3686 60% Garcinia cambogia Extract Garcinia Cambogia Extract (60%)从藤黄Garcinia cambogia果实中提取。藤黄提取物含有丰富的柠檬酸的衍生物-羟基柠檬酸(HCA)。藤黄提取物对减肥有效,并已被用作膳食补充剂。
E3687 Radix Actinidiae Extract Radix Actinidiae Extract来源于藤梨根Radix Actinidiae,即猕猴桃Actinidia chinensis Planch.的根,可通过调控微小核糖核酸(miRNA)的表达发挥抗癌作用。
E3725 Sapindus saponaria Linnaeus nutshell Extract (40%) Sapindus Saponaria Linnaeus Nutshell Extract (40%)提取自无患子Sapindus saponaria L.,具有抗真菌活性。
E3726 Sapindus saponaria Linnaeus nutshell Extract (70%) Sapindus Saponaria Linnaeus Nutshell Extract (70%)提取自无患子Sapindus saponaria L.,具有抗真菌活性。
E3727 Daphne genkwa Sieb.et Zucc. Extract Daphne Genkwa Sieb.Et Zucc. Extract源自 Daphne genkwa Sieb. et Zucc.的干燥花朵,是具有泻药、利尿和消炎作用用于流产的中草药。
E3728 Brassica rapa Extract Brassica Rapa Extract从芸苔科芜菁Brassica Rapa L.中提取,可用于传统医学治疗一些疾病,如糖尿病。
E3729 Ulmus macrocarpa Hance seeds Extract Ulmus Macrocarpa Hance Seeds Extract源自芜夷Ulmus macrocarpa Hance,具有多种生物活性,包括抗氧化、抗炎、抗肿瘤、抗过敏和抗血小板等特性。
E3730 Tetradium ruticarpum fruits Extract Tetradium Ruticarpum Fruits Extract从干燥且接近成熟的吴茱萸 Tetradium ruticarpum (A. Juss.) T.G. Hartley果实中提取提取,在韩医学中,长期用于治疗头痛和胃肠紊乱。
E3731 Chinese Gallnut Extract Chinese Gallnut Extract是从五倍子Melaphis chinensis gallnut中提取的,在905种天然产物的高通量筛选研究中,Chinese Gallnut Extract是人乳酸脱氢酶(LDH)-A最有效的抑制剂。
E3732 Cortex Acanthopanacis Senticosus Extract Cortex Acanthopanacis Senticosus Extract提取自五加Acanthopanax gracilistylus的根皮,具有抗氧化、抗炎、抗增殖等作用。
E3733 Faeces Trogopterori Extract Faeces Trogopterori Extract提取自鼯鼠Trogopterus xanthipes Milne-Edwards的粪便。
E3734 Schisandrae Chinensis fructus Extract Schisandrae Chinensis Fructus Extract来源于五味子,即植物五味子Schisandra chinensis (Turcz.) Baill.的干燥成熟果实。五味子主要用于治疗烦躁、心悸、失眠。五味子及其活性成分在神经系统疾病中具有保护作用,包括脑血管疾病、神经退行性疾病或抑郁症。
E3735 Ficus hirta Vahl Extract Ficus Hirta Vahl Extract从五指毛桃Ficus Hirta Vahl.提取,具有保肝、抗菌、抗炎等生物活性,改善阿尔兹海默小鼠的记忆功能。
E3736 Gymnema sylvestre Extract Gymnema sylvestre Extract提取自萝摩科武靴藤Gymnema sylvestre R. Br.,对改善排尿和糖尿病有效。
E3773 Marasmius Extract Marasmius Extract提取自安络小皮伞菌Marasmius androsaceus,作为唯一能治疗各种类型神经痛的镇痛药用真菌,其治疗偏头痛的作用机制也越来越受到关注。
E3778 Magnoliae Flos Extract Magnoliae Flos Extract是从Flos Magnoliae中分离出来的,这是一种东方草药,通过抑制肥大细胞释放组胺和T细胞分泌细胞因子,常用于缓解过敏性鼻炎,鼻窦炎和头痛的症状。
E3822 Coix Lacryma-Jobi Seed Extract Coix lacryma-jobi seed Extract从薏米Coix lacryma-jobi L.中提取。薏米具有抗炎、降血糖、降低血清中脂质成分含量和降胆固醇活性。
E3837 Citrus Maxima Peel Extract Citrus Maxima Peel Extract 从柚子Citrus Maxima的果皮中提取,对糖尿病治疗有效。
E3647 Pyrrosiae Folium Extract Pyrrosiae Folium Extract是从石韦Pyrrosiae Folium中提取的。
E3041 Alpiniae Katsumadai Extract Alpiniae Katsumadai Extract是从百草果Alpiniae Katsumadai中提取的,可以通过调节癌细胞中的AMPK和Akt/mTOR/p70S6K信号通路,诱导生长抑制和自噬相关的凋亡。
E3061 Castor Bean Extract Castor Bean Extract从蓖麻Ricinus communis中提取,常用于治疗炎症性皮肤病、疖疮、痈、感染袋(脓肿)、中耳炎症和偏头痛。
E3063 Pygeum Topengii Bark Extract Pygeum Topengii Bark Extract从臀果木Pygeum Topengii树皮中提取,有助于前列腺和肾脏健康和一般炎症。
E3123 Rhubarb Extract Rhubarb Extract提取自大黄Rheum palmatum L./Rheum officinale,其中一些植物化学物质可以促进某些参与肠道屏障功能的细菌性别,因此参与调节与急性酒精摄入相关的肝脏疾病的易感。
E3127 Rice Flour Extract Rice Flour Extract是从米粉(Oryza sativa) 中提取的,它含有胆碱且不含麸质,有助于肝脏健康,对患有乳糜泻的人来说是安全的。
E3129 Garlic Extract (1%) Garlic Extract (1%)是从大蒜Allium sativum中提取,可用于常规降压治疗。
E3166 Fermented Blank Bean Extract Fermented Blank Bean Extract是从发酵的菜豆Phaseolus vulgaris L.中提取的,有助于保护人类的消化道,主要是结肠。
E3167 Amomum Kravanh Fruit Extract Amomum Kravanh Fruit Extract提取自白豆蔻Amomum kravanh Pierre ex Gagnep的果实,其精油具有显著的抗氧化活性、抗DNA损伤的保护作用和清除亚硝酸根的活性。
E3174 Eucommia Extract (Bark, Branch and Leaf) 杜仲提取物是从原产于中国的稀有滋补药材杜仲(Eucommiae Cortex)的树皮、枝叶中提取的,对治疗高血压有很好的疗效。
E3201 Honey Extract Honey extract是从蜂蜜(mel)中提取的,由于其抗菌性能在中药中被广泛使用。
E3221 Downy Rosemyrtle Root Extract Downy Rosemyrtle Root Extract提取自中药甘草(Rhodomyrtus tomentosa (Ait.) Hassk.)。
E3289 Knoxia Valerianoides Extract Knoxia Valerianoides Extract从红大戟Knoxia Valerianoides中提取,与其他草药联合应用可用于解毒和治疗癌症和炎症性疾病。
E3365 Weigela Grandiflora Fortune Extract Weigela Grandiflora Fortune Extract从锦带花Weigela Grandiflora Fortune中提取,通过抑制AKT/NF-κB和MAPK信号通路,降低炎症介质的感染介导表达。
E3392 Balsam Pear Extract Balsam Pear Extract从苦瓜Momordica charantia中提取,用于治疗糖尿病。
E3458 Ilex Paraguariensis Extract Ilex Paraguariensis Extract是从马黛茶Ilex Paraguariensis中提取的,它具有必需的 omega-3 脂肪酸和抗氧化特性。
E3485 Matcha Powder Matcha Powder是从抹茶中提取的,含有丰富的抗氧化和抗炎物质。
E3507 Rose-of-Sharon Seed Extract Rose-Of-Sharon Seed Extract是从木槿Hibiscus syriacus L.的种子中提取的,是一种营养价值极高的食品成分。
E3521 Auricledleaf Swallowwort Root Extract Auricledleaf Swallowwort Root Extract提取自青羊参Cynanchum otophyllum Schneid,可能通过激活PPARα转录因子EB,以及增强随后的自噬溶酶体途径,从而减弱了3XTg小鼠的阿尔茨海默病病理和改善认知功能。
E3544 Cattail Pollen Extract Cattail Pollen Extract提取自蒲黄。
E3759 Periploca Sepium Extract Periploca Sepium Extract来自香加皮Periploca sepium,传统上在东方医学中用于治疗类风湿关节炎(RA)。
E3764 Rose Pelargonium Leaf Extract Rose Pelargonium Leaf Extract提取自玫瑰天竺葵的全草。
E3847 Fructus Akebiae Extract Fructus Akebiae Extract提取自预知子Fructus akebiae,用于治疗精神障碍。
E3522 Achyranthes bidentata root Extract Achyranthes Bidentata Root Extract从牛膝Achyranthes bidentata的根中提取,可治疗绝经后骨质疏松症。
E3523 Antrodia cinnamomea Extract Antrodia Cinnamomea Extract是从牛樟芝Antrodia Cinnamomea中提取的,是一种新型的抗他莫西芬耐药乳腺癌药物。
E3524 Oregano Extract Oregano Extract是从牛至草Origanum vulgare中提取的,具有保护心血管、预防癌症和降低胃肠道炎症的功效。
E3525 Origanum vulgare leaf Extract Origanum Vulgare Leaf Extract从牛至Origanum vulgare叶中提取,对百草枯引起的急性肾毒性和肾脏氧化应激有保护作用。
E3526 Clematis apiifolia Extract Clematis Apiifolia Extract是从女萎clematis apiifolia中提取的,其中含有抗氧化反应元素。
E3527 Glossy privet fruit Extract Glossy Privet Fruit Extract是从女贞Ligustrum lucidum的果实中提取的,具有免疫调节作用。
E3528 Parsley Extract Parsley Extract是从欧芹Petroselinum crispum中提取的,具有抗氧化、保肝、保护大脑、抗糖尿病、镇痛、解痉和免疫抑制等药理活性。
E3529 Achillea millefolium Extract Achillea Millefolium Extract从欧蓍草Achillea millefolium中提取,对糖尿病的并发症有保护作用。
E3530 Boat-fruited sterculia seed Extract Boat-Fruited Sterculia Seed Extract是从胖大海boat-fruited sterculia中提取的,对急性炎症有抑制作用。
E3532 Wedelia Extract Wedelia Extract从蟛蜞菊Wedelia chinensis中提取,具有神经药理活性,可能具有镇静作用。
E3533 Loquat leaf Extract Loquat Leaf Extract是从枇杷Eriobotrya japonica的叶中提取的,对非酒精性脂肪肝和糖尿病等代谢综合征有疗效。
E3534 Hops Extract Hops Extract从啤酒花Humulus lupulus 中提取,用于治疗焦虑和情绪障碍。
E3535 Japanese ardisia Extract Japanese Ardisia Extract从紫金牛Ardisia japonica中提取,可诱导人胰腺癌细胞凋亡,抑制细胞增殖。
E3536 Pleurotus ostreatus Extract Pleurotus ostreatus Extract是从平菇Pleurotus ostreatus中提取的,通过细胞凋亡减少白血病细胞的增殖。
E3537 Apple cider vinegar Extract Apple Cider Vinegar Extract是从具有抗菌活性的苹果醋中提取的。
E3538 Apple Extract Apple Extract是从苹果Malus中提取的,它对变异链球菌造成的龋齿具有抗龋作用,并有助于预防龋齿。
E3539 Grape skin Extract Grape Skin Extract是从葡萄Vitis 的果皮中提取的,可调节神经元干细胞增殖并改善空间学习能力。
E3541 Grapefruit Seed Extract Grapefruit Seed Extract是从葡萄柚Citrus paradisi Macf.的种子中提取的,可以作为抗生物膜剂,对金黄色葡萄球菌和大肠杆菌有效。
E3543 Dandelion Extract Dandelion Extract提取自蒲公英Taraxacum,具有抗氧化和抗炎活性。
E3545 Pu-erh tea Extract Pu-erh tea Extract是普洱茶的水提物,可以缓解抗生素引起的肠道炎症,降低肠道病变程度,促进肠道益生菌生长,抑制致病菌。
E3547 Extract of Scandent Schefflera Stem and Leaf Extract of Scandent Schefflera Stem and Leaf提取自七叶莲。
E3548 Chia seed Extract Chia Seed Extract是从芡欧鼠尾草Salvia Hispanica的种子中提取的,它含有一种高度稳定的胰蛋白酶抑制剂,可单独用于细菌管理或与苯唑西林药物联合治疗。
E3549 Qamgur Extract Qamgur Extract是从恰玛古Brassica rapa中提取的,可通过抑制神经炎症和线粒体去极化来预防睡眠剥夺引起的认知缺陷。
E3550 Philippine flemingia root Extract Philippine Flemingia Root Extract是从千斤拔Philippine Flemingia的根中提取。
E3551 Stephania Extract Stephania Extract从千金藤Stephania中提取,通过抑制乙酰胆碱酯酶和氧化应激改善东莨菪碱诱导的小鼠记忆障碍。
E3552 Euphorbia lathyris Extract Euphorbia Lathyris Extract是从千金子Euphorbia lathyris的种子中提取的,具有抗肿瘤活性。
E3553 Climbing groundsel Extract Climbing Groundsel Extract是从千里光Senecio scandens 中提取的。
E3554 Rhizoma homalomenae Extract Rhizoma Homalomenae Extract是从千年健Rhizoma Homalomenae中提取的,具有抗炎活性。
E3555 Acmella oleracea Extract Acmella Oleracea Extract从千日菊Acmella Oleracea中提取,可降低糜酶活性,抑制氧化应激和炎症。
E3556 Pharbitis Extract Pharbitis Extract是从牵牛子Pharbitis nil中提取的,具有抗哮喘的药理活性。
E3557 Radix Peucedani Extract Radix Peucedani Extract是从前胡Peucedani radix中提取的,具有很强的抗炎作用,几个世纪以来一直是治疗呼吸道症状和疾病的重要药物。
E3558 Euryale ferox Extract Euryale ferox Extract源自是芡实Euryale ferox Salisb的种子,具有抗糖尿病、抗氧化和降血脂的作用。
E3559 Radix rubiae Extract Radix Rubiae Extract是从茜草Rubia cordifolia中提取的,具有抗肿瘤、抗氧化、抗血小板聚集、抗炎等作用。
E3560 Incised notopterygium rhizome Extract Incised Notopterygium Rhizome Extract从羌活Notopterygium incisum中提取,通过减弱β-淀粉样蛋白、tau蛋白和神经炎症病理来减轻APP/PS1阿尔茨海默病小鼠的认知缺陷。
E3561 Polygonum fagopyrum seed Extract Polygonum Fagopyrum Seed Extract是从荞麦Fagopyrum esculentum的种子中提取的。
E3563 Eggplant Extract Eggplant Extract是从茄子Solanum melongena中提取的。
E3564 Celery Extract Celery Extract提取自芹菜Apium graveolens,对PMA/离子霉素介导的CD4+ T淋巴细胞活化具有抑制作用。
E3565 Celery seed Extract Celery Seed Extract是从芹菜Apium graveolens的种子中提取的,对PMA/离子霉素介导的CD4+ T淋巴细胞活化具有抑制作用。
E3566 Largeleaf Gentian Root Extract Largeleaf Gentian Root Extract是从秦艽Gentiana macrophylla的根中提取的,可调节CD147/p38/NF-κB通路。
E3567 Ash bark Extract Ash Bark Extract是从白蜡树Fraxinus chinensis的树皮中提取的,具有抗炎作用。
E3568 Natural indigo Extract Natural Indigo Extract是从青黛Polygonum tinctorium中提取的,通过IL-10相关通路抑制葡聚糖硫酸钠诱导的结肠炎。
E3569 Caulis sinomenii Extract Caulis Sinomenii Extract是从青风藤Caulis Sinomenii中提取的。
E3571 Green Walnut Husk Extract Green Walnut Husk Extract是从核桃Juglans regia L.的果皮中提取的。
E3572 Green Tangerine peel Extract Green Tangerine Peel Extract是从青橘Citrus reticulata Blanco的果皮中提取的。
E3580 Ginseng Extract Ginseng Extract提取自人参,是最广泛使用的草药之一,因为它被认为可以改善精力、身体和情绪健康和福祉。
E3645 Pomegranate seed Extract Pomegranate Seed Extract是从石榴Punica granatum的种子中提取的。
E3646 Selaginella Doederleinii Extract Selaginella Doederleinii Extract是从石上柏Selaginella doederleinii中提取的,具有抗氧化和抗增殖活性。
E3649 Centaurea cyanus Extract Centaurea cyanus Extract是从矢车菊Centaurea cyanus中提取的。
E3650 Diospyroskaki leaf Extract Diospyroskaki Leaf Extract是从柿Diospyros kaki Thunb.的叶中提取的。
E3651 Lycopodiastrum casuarinoides Extract Lycopodiastrum casuarinoides Extract是从舒筋草Lycopodiastrum casuarinoides中提取的,具有乙酰胆碱酯酶抑制活性。
E3652 Rehmanniae radix praeparata Extract Rehmanniae radix praeparata Extract是从熟地黄Rehmanniae radix praeparata中提取的,可通过AMPK介导的NF-κB/NLRP3信号通路改善糖尿病。
E3654 Althaea rosea Extract(root) Althaea rosea Extract是从蜀葵Althaea rosea Extract的根中提取的,具有抑制NF-κB的作用。
E3655 Althaea rosea Extract(leaves) Althaea Rosea Extract(Leaves)是从蜀葵Althaea Rosea的叶子中提取的。
E3656 Dichroa febrifuga Extract Dichroa Febrifuga Extract是从蜀漆Dichroa Febrifuga中提取的,它可以抑制 PI3K/AKT 和 MAPK 信号通路
E3657 Salvia japonica Extract Salvia Japonica Extract是从鼠尾草Salvia Japonica中提取的。
E3659 Silybum marianum Extract Silybum marianum Extract是从水飞蓟Silybum marianum中提取的。
E3660 Polypodiodes niponica Extract Polypodiodes Niponica Extract是从水龙骨Polypodiodes Niponica中提取的。
E3661 Prunus persica Extract Prunus persica Extract是从水蜜桃Prunus persica中提取的。
E3662 Buffalo Horn Extract Buffalo Horn Extract是从水牛Bubalus角中提取的。
E3663 Retinerus luffae Fructus Extract Retinerus Luffae Fructus Extract提取自丝瓜Luffa aegyptiaca Miller果实的维管束。
E3664 Luffa Cylindrica Stem Extract Luffa Cylindrica Stem Extract是从丝瓜Luffa aegyptiaca Miller的茎中提取的。
E3665 60% Yucca schidigera Extract 60% Yucca schidigera Extract是从丝兰Yucca schidigera中提取的。
E3666 Chloranthus helostegius Extract Chloranthus Helostegius Extract是从四块瓦Lysimachia paridiformis Franch.中提取的。
E3667 Pine pollen Extract
E3669 Pine Nodular Branch Extract Pine Nodular Branch Extract是从松Pinus Linn的树枝中提取的。
E3670 Pine Bark Extract Pine Bark Extract提取自松树的树皮。松树皮提取物富含生物类黄酮,主要是抗氧化剂原花青素。松树皮提取物可用于预防或治疗与氧化应激相关的各种慢性病。
E3671 Mesembryanthemum spectabile Extract Mesembryanthemum Spectabile Extract是从松叶菊Mesembryanthemum Spectabile中提取的。
E3672 Pine needles Extract Pine Needles Extract是从松Pinus Linn的针叶中提取的。
E3673 Pine nuts Extract Pine Nuts Extract是从松Pinus Linn的果中提取的。
E3674 Caesalpinia sappan Extract Caesalpinia Sappan Extract是从苏木Caesalpinia Sappan中提取的,具有抗癌活性。
E3676 Prunus cerasus Extract Prunus cerasus Extract是从酸樱桃Prunus cerasus中提取的。
E3677 Semen Ziziphi Spinosae Extract Semen Ziziphi Spinosae Extract是从酸枣仁Semen Ziziphi Spinosae中提取的,通过靶向FAK-DOCK180-Rac1-WAVE2-Arp3信号通路可以减轻脂多糖诱导的血脑屏障功能障碍。
E3678 Vitex agnus-castus Extract Vitex Agnus-Castus Extract 提取自穗花牡荆Vitex Agnus-Castus,具有抗胆碱能、抗氧化和抗菌特性。
E3679 Semen aesculi Extract Semen Aesculi Extract从娑罗子Aesculus chinensis Bunge中提取,通过下调LOXL2的表达,抑制上皮-间质转化,从而抑制三阴性乳腺癌的转移。
E3680 Aesculus chinensis Bunge fruits Extract Aesculus chinensis Bunge fruits Extract是从梭罗果(七叶树果实Aesculus chinensis Bunge)中提取的,能够通过下调LOXL2的表达,抑制三阴性乳腺癌的上皮-间质转化,从而抑制三阴性乳腺癌的转移。
E3681 Cynomorium Songaricum Extract Cynomorium Songaricum Extract是从锁阳Cynomorium Songaricum中提取的,具有多种抗氧化作用。
E3683 Santalum album Extract Santalum Album Extract是从檀香Santalum Album中提取的。
E3444 Spirulina Extract Spirulina Extract是从螺旋藻Spirulina中提取的,具有抗氧化、抗癌和神经保护作用。
E3445 Hibiscus sabdariffa flower Extract Hibiscus sabdariffa flower Extract从洛神葵Hibiscus sabdariffa的花中提取,通过增加抗炎细胞因子表达和减少促炎细胞因子表达来增强抗炎作用。
E3446 Chinese Starjasmine stem Extract Chinese Starjasmine Stem Extract是从络石藤Trachelospermum jasminoides的茎中提取的,用于治疗炎症相关疾病。
E3447 Air-Plant herb Extract Air-Plant Herb Extract是从落地生根Tillandsia中提取的,它是一种用于控制2型糖尿病的新型治疗剂。
E3449 Green tea Extract Green Tea Extract是从绿茶Camellia sinensis的叶子中提取的,它影响精神病理学症状、认知和大脑功能。
E3450 Phaseolus radiatus seed Extract Phaseolus Radiatus Seed Extract是从绿豆Vigna radiata的种子中提取的,具有抗氧化活性。
E3451 Mung bean peel Extract Mung Bean Peel Extract是从绿豆Vigna radiata的果皮中提取的,具有抗氧化的特性。
E3452 Green Coffee bean Extract Green Coffee Bean Extract是从绿咖啡豆中提取的,可以增强肥胖人群的抗氧化能力。
E3453 Gnetum parvifolium Extract Gnetum Parvifolium Extract从麻骨风Gnetum Parvifolium中提取,对黄嘌呤氧化酶有抑制作用。
E3454 Verbena herbs Extract Verbena Herbs Extract是从马鞭草Verbena中提取的,具有抗氧化和抗炎的生物活性。
E3455 Puff-ball Extract Puff-Ball Extract提取自马勃Calvatia,对乳腺癌细胞凋亡增殖有抑制作用。
E3456 Purslane Extract Purslane Extract提取自马齿苋Portulaca oleracea,具有抗炎和抗氧化活性。
E3459 Malan Extract Malan Extract提取自菊科植物蟛蜞菊Wedelia chinensis (Osb.)的干燥全草。
E3460 Bones of Cervus elaphus’ Extract Bones Of Cervus Elaphus' Extract从马鹿Cervus Elaphus的骨头中提取,可增加骨形成并抑制骨吸收。
E3462 Coriaria Root Extract Coriaria Root Extract从马桑coriaria根中提取,用于治疗麻木、风热引起的牙痛、痰潴留综合征、外伤、急性结膜炎等。
E3463 Masson pine needle Extract Masson Pine Needle Extract是从马尾松Pinus massoniana的针叶中提取的,对胃肠道疾病和氧化应激有帮助。
E3464 Maca extract Maca Extract从玛卡Lepidium meyenii中提取,具有调节性功能障碍、神经保护作用、增强记忆力、抗抑郁、抗氧化、抗癌、抗炎和皮肤保护作用。
E3465 Radix Ophiopogonis Extract Radix Ophiopogonis Extract是从具有抗糖尿病活性的麦冬Radix Ophiopogonis中提取的。
E3466 Barley grass Extract Barley Grass Extract是从麦苗Hordeum vulgare中提取的,其中含有抗肿瘤化合物。
E3467 Malt fruit Extract Malt fruit Extract是从大麦hordeum vulgare的果实中提取的。
E3468 Chasteberry Extract Chasteberry Extract是从穗花牡荆Vitex agnus-castus的干燥成熟果实中提取的,可用于治疗许多激素相关的妇科疾病。
E3470 Mango leaf Extract Mango Leaf Extract是从芒果Mangifera indica的叶子中提取的,可以减轻肌肉疼痛和损伤,加速肌肉性能的恢复。
E3472 Spicate clerodendranthus Extract Spicate Clerodendranthus Extract是从猫须草Spicate Clerodendranthus中提取的,对呼吸道炎症和上呼吸道疾病如口干舌燥、口臭、口苦等有疗效。
E3473 Ternate buttercup root Extract Ternate Buttercup Root Extract是从猫爪草Ternate Buttercup的根中提取的,能增强免疫系统的活性,减少炎症,清除被称为自由基的有害颗粒,并摧毁癌细胞。
E3474 Fructus Chebulae Extract Fructus Chebulae Extract从诃子Terminalia chebula Retz.的成熟果实中提取,可挽救神经元细胞死亡,对抗缺血相关损伤。
E3475 Coleus forskohlii Extract Coleus Forskohlii Extract是从毛喉鞘蕊花Coleus Forskohlii中提取的,这是一种流行的减肥膳食补充剂成分。
E3477 Rose hip Extract Rose Hip Extract从玫瑰Rosa L.的果实中提取,用于治疗肾结石、肠胃疾病、高血压和呼吸系统疾病,如支气管炎、咳嗽和感冒。
E3482 Buddleja Officinalis Extract Buddleja Officinalis Extract从密蒙花Buddleja officinalis的中提取的,据报道在传统的东方草药中对治疗炎症、结膜高血压和头痛有效。
E3483 Melissa axillaris Extract Melissa axillaris Extract是从蜜蜂花Melissa axillaris中提取的。
E3486 Jasmine flower Extract Jasmine Flower Extract是从茉莉Jasminum的花中提取的,含有降低催乳素的物质。
E3488 Fucus vesiculosis Extract Fucus Vesiculosis Extract是从具有抗真菌特性的墨角藻Fucus vesiculosus中提取的。
E3489 Cuttlefish grass Extract Cuttlefish Grass Extract提取自墨鱼草。
E3487 Ecliptae Herba Extract Ecliptae Herba Extract是从墨旱莲Eclipta中提取的,具有抗骨质疏松作用。
E3490 Peony flower Extract Peony Flower Extract从牡丹Paeonia花中提取,用于治疗各种代谢性疾病。
E3491 Paeonia suffruticosa root bark Extract Paeonia Suffruticosa Root Bark Extract从牡丹Paeonia suffruticosa的根皮中提取,通过增加抗氧化活性表现出潜在的抗炎特性。
E3492 Vitex negundo seed Extract Vitex Negundo Seed Extract是从牧荆Vitex negundo的果实中提取的,用于治疗风湿病和关节炎症。
E3493 Oyster Extract Oyster Extract是从牡蛎Ostreidae中提取的,它是一种用于骨骼形成和生长的营养补充剂。
E3494 Oyster Shell Extract Oyster Shell Extract是从牡蛎Ostreidae的壳中提取的,具有抗炎作用。
E3495 Oyster Peptide Oyster Peptide可增强垂体性腺轴功能,降低ROS生成。
E3497 Momordicae Semen Extract Momordicae Semen Extract是从木鳖子Momordicae semen中提取的,具有抗胃炎和伤口愈合的作用。
E3498 Pigeon pea leaves Extract Pigeon Pea Leaves Extract是从木豆Cajanus cajan (L.) Millsp的叶子中提取的,具有抗菌、抗炎、抗结核、抗氧化、神经保护、抗高血压、抗高血糖和抗癌的特性。
E3484 Ashitaba Extract Ashitaba Extract是从当归Angelica keiskei中提取的,它可以通过调节脂肪组织和肝脏中的脂质代谢来预防肥胖。
E3480 Rosemary Extract Rosemary Extract从迷迭香Salvia rosmarinus中提取的,具有保肝、抗真菌、杀虫、抗氧化、抗菌等生物活性。
E3478 Rose Extract Rose Extract是从玫瑰Rosa中提取的,具有美白和抗皱活性。
E3476 Myrrh Extract Myrrh Extract是从没药Commiphora myrrha中提取的,用于治疗炎症性肠病。
E3448 Chinese Astilbe rhizome Extract Chinese Astilbe Rhizome Extract是从落新妇Astilbe chinensis (Maxim.) Franch. et Savat.的全草中提取的,具有较强的抗氧化活性。
E3469 Cranberry Extract Cranberry Extract是从蔓越莓Vaccinium macrocarpon中提取的,对尿路感染具有有益的作用。
E3499 Basella rubra Extract Basella Rubra Extract是从木耳菜Basella Rubra中提取的,可以作为天然抗氧化剂的来源。
E3500 Agaric Extract Agaric Extract是从木耳agaricales中提取的,具有抗炎和相关药理活性。
E3501 Hibiscus mutabilis flower Extract Hibiscus Mutabilis Flower Extract是从木芙蓉Hibiscus mutabilis的花中提取的,具有预防过敏的作用。
E3502 Papaya Extract Papaya Extract是从具有抗癌活性的木瓜Carica papaya中提取的。
E3504 Oroxylum indicum seed Extract Oroxylum Indicum Seed Extract是从木蝴蝶Oroxylum Indicum种子中提取的,具有较强的抗氧化活性。
E3506 Hibiscus bark Extract Hibiscus Bark Extract是从木槿Hibiscus的树皮中提取的,具有抗抑郁样和神经保护作用。
E3508 Magnolia Obovata Extract Magnolia Obovata Extract是从木兰magnolia obovata中提取的,通过增强GABA受体和抗神经炎症机制具有抗焦虑作用。
E3509 Akebia quinata Extract Akebia Quinata Extract从木通akebia quinata中提取,具有抗肥胖和降血脂的作用。
E3510 Costustoot Extract Costustoot Extract是从木香costus的根中提取的,具有抗菌特性,对肠道细菌的再生具有抑制作用。
E3512 Milk thistle Extract Milk Thistle Extract是从水飞蓟Silybum marianum中提取的,是一种治疗胃肠道癌症的药物。
E3513 Pumpkin seed Extract Pumpkin Seed Extract是从南瓜Cucurbita的种子中提取的,可用于治疗下尿路症状。
E3514 Burdock root Extract Burdock Root Extract从牛蒡Arctium的根中提取,具有抗菌被膜活性。
E3515 Great Burdock Achene Extract Great Burdock Achene Extract从牛蒡Arctium lappa L.的干燥成熟果实中提取,具有抗心肌缺血再灌注损伤的作用。
E3516 Beautiful millettia root Extract Beautiful Millettia Root Extract是从牛大力Millettia specisoa Champ.根中提取的,具有细胞毒作用和抗氧化活性。
E3517 Ox-gall Extract Ox-Gall Extract是从牛胆中提取的,含有抗氧化成分。
E3518 Daphniphyllum calycinum Extract Daphniphyllum Calycinum Extract是从牛耳枫Daphniphyllum calycinum中提取的,具有抗氧化活性。
E3519 OX liver Extract Ox Liver Extract是从牛的肝脏中提取的,具有预防肝癌的作用。
E3520 Goose Grass Extract Goose Grass Extract是从牛筋草Eleusine indica中分离得到,具有抗氧化、抗菌和抗癌活性。
E3200 Bee Pollen Extract Bee Pollen Extract是从工蜂采集的花粉中提取的,是天然抗氧化剂的潜在来源。
E3203 Hibiscus Flower Extract 芙蓉花提取物是从木芙蓉(Hibiscus mutabilis)的花中提取的,由于其抗氧化和降血脂作用,具有许多药用和抗癌特性。
E3204 Citri Sarcodactylis Fructus Extract Citri Sarcodactylis Fructus Extract是从佛手Citri Sarcodactylis Fructus中提取的,具有疏肝调气、止胃止痛、祛湿化痰的作用。
E3206 Spirodelae Herba Extract Spirodelae Herba Extract是从螺旋藻Spirodelae中提取的,可能是治疗特应性皮炎的有效治疗剂。
E3207 Blighted Wheat Extract Blighted Wheat Extract是从浮小麦中提取的,这是临床上治疗抑郁症的有效且耐受性良好的处方。
E3210 Rubi Fructus Extract Rubi Fructus Extract是从覆盆子Rubi Fructus中提取的,具有抗肿瘤、抗氧化和抗炎活性。
E3212 Prunus Humilis Bunge Extract Prunus Humilis Bunge Extract是从钙果Prunus Humilis Bunge 中提取的,它是一种潜在的抗氧化剂。
E3213 Glycyrrhizae Rhizoma Extract Glycyrrhizae Rhizoma Extract 提取自中药甘草(Glycyrrhizae Rhizoma)。
E3214 Nardostachyos Rhizoma Extract Nardostachyos Rhizoma Extract提取自甘松Nardostachyos Rhizoma,用于治疗心血管疾病。
E3215 Kansui Radix Extract Kansui Radix Extract是从甘遂Kansui Radix中提取的,用于治疗糖尿病、腹水和白血病。
E3216 Citrus Extract Citrus Extract是从柑橘(Citrus reticulata Blanco)的果实中提取的,可用作防癌食品添加剂和抗癌剂。
E3217 Penthorum Chinense Pursh Extract Penthorum Chinense Pursh Extract是从赶黄草Penthorum Chinense Pursh中提取的,用于治疗外伤、水肿和肝脏疾病。
E3218 Zingiberis Rhizoma Extract Zingiberis Rhizoma Extract是从干姜Zingiber officinale中提取的,对神经系统、心脑血管系统具有药理作用,并具有止吐、抗菌、抗肿瘤、抗炎、抗氧化等作用。
E3219 Ilex Asprella Extract Ilex asprella Extract是从岗梅Ilex asprella中提取的。
E3222 Sedum Aizoon Extract Sedum Aizoon Extract是从高钙菜(Sedum Aizoon)中提取的,它对从海鲜中分离出的腐败希瓦菌具有显著的抗菌活性。
E3223 Alpiniae Officinarum Rhizoma Extract Alpiniae Officinarum Rhizoma Extract从高良姜Alpiniae Officinarum Rhizoma中提取,对乙酰胆碱酯酶(AChE)有抑制作用,可用于治疗阿尔茨海默病。
E3224 Puerariae Lobatae Radix Extract Puerariae Lobatae Radix Extract是从中药葛根(Puerariae Lobatae Radix)中提取的,具有抗氧化作用。
E3225 Pueraria Flower Extract Pueraria Flower Extract是从中药葛花(Pueraria lobata(Willd.)Ohwi)中提取的。
E3226 Devil's Claw Extract Devil'S Claw Extract是从钩果草Harpagophytum 中提取的,可用于多种健康状况,包括消化不良、发烧、过敏反应和风湿病。
E3340 Jiao San Xian Extract Jiao San Xian Extract是从焦三仙即焦麦芽(Hordeum vulgare L.)、焦山楂(Crataegus pinnatifida Bge.)和焦神曲中提取的。
E3354 Camellia nitidissima Extract Camellia nitidissima Extract是从金花茶Camellia chrysantha中提取的,这是一种潜在的抗肥胖的益生元营养物质,可以防止体重增加,改善肥胖相关的血脂异常和高血糖,抑制肝脏脂肪积累,调节肠道菌群。
E3355 Cinchona Extract Cinchona Extract从金鸡纳中提取,用于治疗疟疾。
E3356 Witch hazel Extract Witch hazel Extract是从植物金缕梅(Hamamelis mollis Oliver )中提取的。
E3357 Lysimachia christinae Hance extract Lysimachia christinae Hance extract是从金钱草(Lysimachia christinae Hance)中提取的,它通过影响肠道菌群来预防小鼠胆固醇结石。
E3358 Rhizoma Fagopyri Dibotryis Extract Rhizoma Fagopyri Dibotryis Extract是从金荞麦Rhizoma Fagopyri Dibotryis中提取的,用于治疗急性肺损伤。
E3360 Lonicera Japonica Extract Lonicera Japonica Extract (Japanese honeysuckle Extract)源自金银花 Lonicera japonica,即日本忍冬(Japanese honeysuckle),具有解热、抗生素、抗氧化和抗炎活性。
E3361 Calendula officinalis flower Extract Calendula Officinalis Flower Extract是从金盏菊Calendula Officinalis的花中提取的,具有伤口愈合的特性。
E3362 Enoki Mushroom Extract Enoki Mushroom Extract从金针菇Flammulina velutipes中提取,有助于降低血糖、血压和胆固醇。
E3363 Decumbent Bugle Herb Extract Decumbent Bugle Herb Extract提取自中药筋骨草(Ajuga ciliata Bunge.),具有抗氧化特性。
E3364 Physalis Alkekengi Extract Physalis Alkekengi Extract从锦灯笼Physalis alkekengi中提取,通过抑制氧化应激、炎症和细胞凋亡对高血糖具有作用,使其成为糖尿病的良好辅助选择。
E3366 Fineleaf Schizonepeta Herb Extract Fineleaf Schizonepeta Herb Extract是从荆芥Schizonepeta的叶子中提取的,它是一种具有解热、消炎、镇痛和止血作用的传统药物。
E3367 Garlic chives Extract Garlic chives Extract从韭菜Allium tuberosum中提取,为NLRP3炎性体驱动疾病的治疗提供了一种新的治疗方法。
E3368 Chinese Chive seed Extract Chinese Chive Seed Extract是从韭菜Allium tuberosum的种子中提取的,具有温肾壮阳的功效。
E3369 Radix Platycodonis Extract Radix Platycodonis Extract是从桔梗(Platycodon grandiflorus)中提取的,具有多种药理活性。
E3371 Chrysanthemi Extract Chrysanthemi Extract从菊花Flos Chrysanthemi中提取,常用于治疗感冒、流感、头痛、视力模糊、眼红、头晕、皮肤溃疡等。
E3372 Chicory Extract Chicory Extract是从菊苣Cichorium intybus中提取的,可以作为天然着色剂或食品中的抗氧化剂。
E3374 Exocarpium Citri Rubrum Extract Exocarpium Citri Rubrum Extract是从橘红Exocarpium Citri Rubrum中提取的,具有护胃除湿化痰的作用。
E3376 Saw palmetto Extract Saw Palmetto Extract从锯叶棕Serenoa repens中提取,具有抗雄激素、促凋亡和抗炎作用。
E3377 Symphytum officinale Extract Symphytum officinale Extract从聚合草Symphytum officinale中提取,在民间医学中常用于促进伤口愈合、消炎和治疗骨折。
E3378 Selaginella Extract Selaginella Extract从卷柏Selaginella中提取,具有相当的生物学特性,可用于新兴护理中的疼痛管理。
E3379 Cassia seed Extract Cassia seed Extract是从决明(Cassia toraLinn)的种子中提取的,具有影响多种生物学过程和途径的潜力,包括对平滑肌细胞增殖、炎症反应、肿瘤坏死因子(TNF)信号通路的正调控 、血管内皮生长因子(VEGF)信号通路和花生四烯酸(ARA)代谢。
E3380 Coffee fruit Extract Coffee Fruit Extract是从咖啡Coffea的果实中提取的,可改善老年人的脑源性神经营养因子(brain-derived neurotrophic factor, BDNF)、认知功能和情绪。
E3382 Camu Camu fruit Extract Camu Camu fruit Extract是从桃金娘科卡姆果Myrciaria dubia McVaugh的果实中提取的,有助于预防氧化应激和由高糖水平引起的皮肤炎症。
E3385 Cocoa Extract Cocoa Extract是从可可Theobroma cacao中提取的,具有抗氧化特性并提供抗氧化和硝化保护。
E3386 Wormwood Extract Wormwood Extract从苦艾Artemisia absinthium中提取,具有抗氧化、抗真菌、抗菌、驱虫、抗溃疡、抗癌、保肝、保护神经、抗抑郁、镇痛、免疫调节和细胞毒活性。
E3388 Latifolin Extract Ilex kudingcha C.J. Tseng Extract从苦丁茶Ilex kudingcha C.J. Tseng中提取,具有广泛的药理特性,包括抗氧化、保肝、抗菌、抗组胺、抗癌、神经保护等生物作用。
E3389 Sophora alopecuroides seed Extract Sophora Alopecuroides Seed Extract是从苦豆子Sophora alopecuroides的种子中提取的,具有抗炎活性。
E3391 Balsam Pear Powder Balsam Pear Powder提取自苦瓜Momordica charantia,传统上被认为对健康有益,主要是对糖尿病有治疗作用。
E3393 Fructus azedarach Extract Fructus azedarach Extract是从苦楝皮(Fructus azedarach)中提取的。
E3394 Quassia Extract Quassia Extract从苦木科植物Quassia中提取,可用于治疗糖尿病和相关的血脂异常。
E3395 Tartary buckwheat Extract Tartary buckwheat Extract从苦荞Tartary buckwheat中提取,具有抗氧化、低胆固醇血症、抗炎症等生物活性作用。
E3396 Bitter almond Extract Bitter almond Extract是从苦杏仁( Semen Armeniacae Amarum.)中提取的。
E3397 Coltsfoot Extract Coltsfoot Extract从款冬花Tussilago farfara中提取,用于缓解人类的炎症以及呼吸道和传染病。
E3398 Sunflower dish Extract Sunflower dish Extract是从向日葵中提取的,具有抗氧化、抗菌、抗增殖和DNA保护作用。
E3399 Kelp Extract Kelp Extract从昆布Laminariales中提取,可减少内源性活性氧的产生。
E3400 Chili pepper Extract Chili Pepper Extract是从辣椒Capsicum annuum中提取的,它是治疗各种疾病的良好药物,例如血压升高和血清甘油三酯和胆固醇水平升高、心肌梗塞、关节炎和偏头痛。
E3401 Polygonum hydropiper Extract Polygonum hydropiper Extract从辣廖Polygonum hydropiper中提取,通过抗氧化和抗炎途径对胃损伤有保护作用。
E3402 Moringa oleifera leaf Extract Moringa oleifera是从辣木Moringa oleifera的叶子中提取的,含有抗氧化剂、抗生素和营养物质,包括维生素和矿物质。
E3403 Moringa pterygosperma seed Extract Moringa pterygosperma seed Extract是从传统药用的尤辣木Moringa pterygosperma种子中提取而成。
E3404 Raphanus sativus seed Extract Raphanus sativus seed Extract从莱菔 Raphanus sativus种子中提取,具有伤口愈合特性。
E3405 Cymbidium ensifolium Extract Cymbidium ensifolium Extract从兰草Cymbidium ensifolium中提取,对多种癌细胞有很好的抗癌作用。
E3407 Blueberry Extract Blueberry Extract是从蓝莓Vaccinium Section Cyanococcus中提取的,具有抗氧化、抗炎和神经保护的特性。
E3408 Radix Euphorbiae Ebracteolatae Extract Radix Euphorbiae Ebracteolatae Extract是从狼毒(Radix Euphorbiae Ebracteolatae)中提取的,它通过抑制肾脏中的PKC活性来调节水通道蛋白。
E3409 Geranium wilfordii Extract Geranium wilfordii Extract是从老颧草(Geranium wilfordii)中提取的,具有抗病毒活性。
E3406 Blue indigo Extract Blue indigo Extract从蓝靛果Lonicera caerulea中提取,用于治疗细菌感染、胃肠道疾病和代谢性疾病。
E3410 Tripterygium wilfordii Extract Tripterygium wilfordii Extract提取自雷公藤(Tripterygium wilfordii),其有效成分可通过抑制PI3K/AKT/mTOR信号通路诱导自噬。
E3411 Veratrum nigrum L. Extract Veratrum nigrum L. Extract是从藜芦(Veratrum nigrum L.)中提取的,具有抗炎、抗氧化、抗癌等药理作用。
E3412 Quinoa Extract Quinoa Extract是从藜麦Chenopodium quinoa Willd.中提取的,用于预防和治疗肥胖和肥胖相关疾病。
E3413 Plum Extract Plum Extract提取自李子Prunus domestica,由于其能够促进肌肉生成,刺激肌肉蛋白质合成,抑制蛋白质降解,对肌肉有健康益处。
E3414 Semen litchi Extract Semen litchi Extract是从荔枝Litchi chinensis中提取的,具有抗肝癌作用,并通过靶向VEGFR抑制肝细胞癌血管生成。
E3415 Forsythia suspensa Extract Forsythia suspensa Extract是从连翘(Forsythia suspensa)中提取的。
E3416 Lotus seed Extract Lotus seed Extract是从荷花Nelumbo nucifera种子中提取的,具有抗氧化、抗炎、抗癌等多种功效。
E3417 Nitidum Extract Nitidum Extract是从两面针Zanthoxylum Nitidum中提取的,以抗炎镇痛作用而闻名。
E3418 Rhizoma Anemones Raddeanae Extract Rhizoma Anemones Raddeanae Extract从两头尖Anemone raddeana Regel的根茎中提取,用于治疗风寒症状、手足病痉挛、关节痛、溃疡痛。
E3419 Ganoderma lucidum Extract Ganoderma lucidum Extract从灵芝(Ganoderma lucidum)中提取,可调节Nrf2和Nrf2相关蛋白。
E3420 Trumpet creeper Extract Trumpet creeper Extract是从凌霄花Campsis中提取的,具有抗菌和抗真菌的特性。
E3421 Diverse wormwood herb Extract Diverse wormwood herb Extract提取自中药刘寄奴(Herba Artemisiae Anomalae).
E3422 Spearmint Extract Spearmint Extract是从留兰香Mentha spicata中提取的,这可能是一种对认知健康有益的营养干预。
E3423 Gentian Extract Gentian Extract是从龙胆草(Adenophora capillaris)中提取的。
E3424 Solanum nigrum Extract Solanum nigrum Extract从龙葵(Solanum nigrum Linn.)中提取,在体内和体外均具有抗肿瘤、抗炎、抗氧化、抗菌和神经保护作用。
E3425 Dragon's blood Extract Dragon'S Blood Extract是从龙血树Dracaena draco树脂中提取的,具有抗血管生成活性和抗肝癌活性。
E3426 Piper betle L. Extract Piper Betle L. Extract是从蒌叶Piper betel l.中提取的,这是一种潜在的伤口愈合剂来源。
E3427 Uniflower swisscentaury root Extract Uniflower swisscentaury root Extract提取自漏芦(Rhaponticum uniflorum (L.) DC.)的根,可通过Nrf2/HO-1信号通路缓解炎症反应。
E3428 Reed rhizome Extract Reed rhizome Extract是从中药芦根,即芦苇(Phragmites australis)的根中提取的。
E3429 Aloe vera Extract Aloe vera Extract提取自芦荟Aloe vera,传统上被用于治疗皮肤损伤和消化问题,因为它具有抗炎、抗菌和伤口愈合的特性。
E3431 Asparagus Extract Asparagus Extract从芦笋Asparagus officinalis中提取,含有适应性、神经保护、抗氧化、抗炎和益智活性。
E3432 Calamine Extract Calamine Extract从炉甘石中提取,可减轻儿童皮肤刺激。
E3434 Deer antler velvet Extract Deer Antler Velvet Extract提取自鹿茸,可刺激皮肤和毛细胞的生长。
E3435 Pyrola herb Extract Pyrola Herb Extract来自鹿衔草Pyrola,可作为绝经后骨质疏松的替代治疗药物。
E3436 Liquidambar formosana Extract Liquidambar Formosana Extract从金缕梅科植物枫香树Liquidambar Formosana的干燥成熟果实中提取,可通过诱导细胞凋亡抑制肉瘤癌细胞。
E3437 Apocynum venetum Extract Apocynum Venetum Extract从罗布麻Apocynum Venetum中提取,有助于改善睡眠质量。
E3438 Momordica grosvenori Extract Momordica Grosvenori Extract从罗汉果Siraitia grosvenorii中提取,通过上调HO-1而具有抗糖尿病作用,可用于治疗糖尿病。
E3439 Basil Extract Basil Extract从罗勒Ocimum basilicum中提取,可用于肝癌的治疗。
E3440 Tamarindus indica seed Extract Tamarindus indica seed Extract提取自罗望子Tamarindus indica种子提取物,有助于减轻炎症和炎症引起的软骨退变。
E3441 Radish root Extract Radish Root Extract从萝卜Raphanus sativus中提取,具有抗糖尿病作用,适合糖尿病患者食用。
E3442 Radish leaves Extract Radish Leaves Extract是从萝卜Raphanus sativus的叶片中提取的提取物,具有抗氧化和抗癌的特性。
E3359 Honeysuckle flower Extract Honeysuckle flower Extract是从中药金银花(Lonicera japonica Thunb)中提取的,具有抗菌、抗病毒、抗炎的特性。
E3811 Cashew Extract Cashew Extract 从腰果Anacardium occidentale中提取,可降低低密度脂蛋白胆固醇水平,并因其高镁含量可能有助于预防心脏病。
E3812 Rhamnus Cathartica Extract Rhamnus Cathartica Extract 提取自药鼠李Rhamnus cathartica,具有抗菌活性。
E3813 Chrysanthemum Indicum Extract Chrysanthemum Indicum Extract 是从野菊花Chrysanthemum indicum L.中提取的,它是一种潜在的肥胖症及其相关并发症的治疗剂。
E3814 Phyllanthus Urinaria Extract Phyllanthus Urinaria Extract 是从叶下珠Phyllanthus urinaria (L.) 中提取的,用于治疗黄疸、糖尿病、疟疾和肝脏疾病。
E3816 Emilia Sonchifolia Extract Emilia Sonchifolia Extract 从一点红Emilia sonchifolia中提取,它是一种有效的免疫反应调节剂。
E3817 Eucalyptus Globulus Fruit Extract Eucalyptus Globulus Fruit Extract 从一口钟Eucalyptus globulus的果实中提取,具有抗癌活性。
E3818 Solidago Decurrens Extract Solidago Decurrens Extract 提取自一枝黄花Solidago decurrens,可药用促进止血和治疗各种疾病,包括蛇咬伤、痈肿和疔疮。
E3820 Leonurus Japonicus Extract Leonurus Japonicus Extract 从益母草Leonurus japonicus中提取,具有抗菌、抗癌、保肝的作用。
E3821 Alpinia Oxyphyllae Extract Alpinia Oxyphyllae Extract 提取自益智仁Alpinia oxyphyllae,在调节与β-淀粉样蛋白沉积、tau 蛋白磷酸化、慢性炎症、氧化应激相关的多种信号通路方面具有有效的活性。
E3824 Scepteridium Ternatum Extract Scepteridium Ternatum Extract 提取自阴地蕨Scepteridium ternatum,用于治疗哮喘。
E3825 Herba Artemisiae Capillaris Extract Herba Artemisiae Capillaris Extract 提取自茵陈Herba artemisiae capillaris,可预防糖尿病肾病。
E3826 Tremella Extract Tremella Extract 从银耳Tremella中提取,具有抗疲劳和抗缺氧作用。
E3827 Ginkgo Biloba Extract 银杏叶提取物是从银杏树Ginkgo biloba L.的叶子中提取的。银杏叶提取物应用于多种疾病,包括抑郁情绪、多发梗塞性痴呆、脑功能不全(以记忆障碍、注意力不集中、焦虑和困惑等症状为特征)、心肌缺血、中风、血栓形成和外周闭塞性动脉病(POAD)。
E3829 Epimedium Brevicornu Extract Epimedium Brevicornu Extract 提取自淫羊藿Epimedium brevicornu Maxim,具有抗炎作用。
E3830 Prunus Serrulata Extract Prunus Serrulata Extract 提取自樱花Prunus serrulata,可作为天然抗氧化和天然抗病毒剂。
E3831 Cherry Powder Extract (Pink) Extract Cherry Powder Extract (Pink) Extract提取自樱桃果Prunus avium,具有抗氧化和抗炎特性。
E3832 Cherry Extract Cherry Extract 是从樱桃Prunus avium中提取的,具有抗氧化和抗炎特性。
E3834 Jasminum Nudiflorum Extract Jasminum Nudiflorum Extract 从迎春花Jasminum nudiflorum中提取,有助于治疗皮肤病、鼻炎、鼻出血、感染和伤口。
E3835 Cordyceps Militaris Extract Cordyceps Militaris Extract 从蛹虫草Cordyceps militaris中提取,通过caspase-3诱导细胞凋亡和细胞焦亡,可用作抗癌剂。
E3836 Cole Flowers Extract Cole Flowers Extract提取自油菜花Brassica oleracea var. botrytis,具有抗癌特性。
E3838 Phyllanthus Emblica Extract Phyllanthus Emblica Extract提取自余甘子Phyllanthus emblica,具有抗糖尿病、降血脂、抗菌、抗氧化、抗溃疡、保肝、保护胃和化学预防的特性。
E3839 Houttuynia Cordata Extract Houttuynia Cordata Extract从鱼腥草Houttuynia cordata中提取,通过抗炎作用改善膀胱损伤并改善膀胱症状。
E3840 Ulmus Pumila Bark Extract Ulmus Pumila Bark Extract提取自榆树皮Ulmus pumila L.,可预防由过量产生一氧化氮介导的炎症性疾病。
E3841 Kale Extract Kale Extract提取自羽衣甘蓝Brassica oleracea var. acephala,具有大量营养素和植物化学成分和生物活性。
E3842 Corn Extract Corn Extract提取自玉米Zea mays,具有抗氧化活性。
E3843 Corn Stigma Extract Corn Stigma Extract从玉米Zea mays的花柱和柱头中提取,具有良好的抗氧化性能,可作为食品包装的原料。
E3844 Polygonatum Odoratum Extract Polygonatum Odoratum Extract从玉竹Polygonatum odoratum中提取,可抑制高糖诱导的肾小管上皮细胞凋亡,减少氧化应激。
E3845 Radix Curcumae Root Extract Radix Curcumae Root Extract提取自郁金Curcuma longa L.的根,具有抗肿瘤和抗转移活性,可用于治疗和预防乳腺癌转移。
E3846 Semen Pruni Extract Semen Pruni Extract提取自郁李仁Semen pruni,用于水肿、皮肤癣菌病、高血压、便秘、慢性气管炎等病症。
E3848 Hypericum Sampsonii Extract Hypericum Sampsonii Extract从元宝草Hypericum sampsonii中提取,通过调节RXRalpha的亚细胞定位诱导癌细胞凋亡。
E3849 Scrophularia Ningpoensis Extract Scrophularia Ningpoensis Extract从元参Scrophularia ningpoensis Hemsl.中提取,具有潜在的抗氧化和抗炎活性。
E3850 Rhizoma Corydalis Extract Rhizoma Corydalis Extract从延胡索Rhizoma corydalis中提取,可用于预防慢性药物依赖的复发。
E3851 Radix Polygalae Extract Radix Polygalae Extract提取自远志Radix Polygalae,用于治疗各种精神疾病。
E3852 Oenothera Biennis Extract Oenothera Biennis Extract提取自月见草Oenothera biennis L.,具有很高的抗炎特性。
E3853 Blueberry Fruit Extract Blueberry Fruit Extract从越橘Vaccinium的果实中提取,有助于维持血糖水平,减少氧化应激,抗炎作用,预防心血管疾病,抗菌和抗肿瘤活性。
E3854 Coriolus Versicolor Extract Coriolus Versicolor Extract从云芝Coriolus versicolor中提取,对癌细胞和内皮细胞具有细胞毒活性,并具有抑制与炎症相关的促肿瘤因子表达的能力。
E3857 Gieditsia Sinensis Lam Fruit Extract Gieditsia Sinensis Lam Fruit Extract提取自皂角树Gleditsia sinensis Lam.的果实,用于治疗肥胖和血栓形成。
E3858 Quillaia Extract Quillaia Extract从皂树皮Quillaja中提取,可用作软饮料中的发泡剂。
E3859 Lycopus Extract Lycopus Extract从泽兰Lycopus中提取,通过抑制TGF-β信号通路改善足细胞损伤。
E3860 Euphorbia Helioscopia Extract Euphorbia Helioscopia Extract提取自泽漆Euphorbia helioscopia L.,已被用于治疗各种疾病,包括水肿、痰咳、疟疾、痢疾、结痂、结核性瘘管、骨髓炎和癌症。
E3861 Rhizoma Alismatis Extract Rhizoma Alismatis Extract从泽泻Alismatis rhizoma中提取,对代谢综合征有治疗作用。
E3862 Japanese Xylosma Twig Extract Japanese Xylosma Twig Extract是从柞木枝中提取的,具有抗菌活性。
E3863 Swertia Bimaculata Extract Swertia Bimaculata Extract从獐牙菜Swertia bimaculata中提取,具有抗炎和抗HIV的作用。
E3864 Cockroach Extract Cockroach Extract从蟑螂中提取,用于过敏诊断和蟑螂特异性免疫治疗。
E3865 Catharanthus Roseus Extract Catharanthus Roseus Extract从长春花Catharanthus roseus中提取,用作抗糖尿病和抗癌剂。
E3867 Fritillariae Thunbergii Bulbus Extract Fritillariae Thunbergii Bulbus Extract提取自浙贝母Fritillariae thunbergii球茎,用于治疗病理性感冒和湿痰引起的咳嗽和胸闷气道症状。
E3868 Pearl Extract Pearl Extract从珍珠中提取,可抑制内皮素,从而通过拮抗内皮素,安全有效地美白肌肤。
E3869 Anemarrhena Extract Anemarrhena Extract从知母Anemarrhena rhizome中提取,有助于增加海马齿状回的细胞增殖和神经肽Y的表达。
E3870 Gardenia Fruit Extract Gardenia fruit Extract是从茜草科的开花植物栀子(Gardenia jasminoides Ellis.)果实中提取的。栀子不仅用作食用色素,还用作治疗肝病、头痛、黄疸、炎症和高血压的药物。
E3871 Valeriana Root Extract Valeriana Root Extract从蜘蛛香Valeriana officinalis L.的根中提取,有助于治疗睡眠问题和相关疾病。
E3872 Hovenia Dulcis Fruit Extract Hovenia Dulcis Fruit Extract提取自枳椇Hovenia dulcis的果实,具有保肝解酒解毒等作用。
E3873 Hovenia Dulcis Seed Extract Hovenia Dulcis Seed Extract提取自枳椇Hovenia dulcis的种子,可能是很好的天然抗氧化来源,对酒精性肝病等氧化性疾病有保护作用。
E3874 Hovenia Dulcis Extract Hovenia Dulcis Extract从枳椇Hovenia dulcis中提取,可减少高脂饮食引起的肝脏脂质积累和高甘油三酯血症。
E3875 Unripe Bitter Orange Extract Unripe Bitter Orange Extract是从枳citrus unshiu的苦果中提取的,是一种有效的抗过敏功能食品。
E3877 Processed Cyperus Extract Processed Cyperus Extract提取自制香附Cyperus rotundus Lin.,用于治疗胃病和情绪障碍。
E3878 Stalactitum Extract Stalactitum Extract从钟乳石Stalactitum中提取,可用作抗哮喘药。
E3879 Glabrous Sarcandra Herb Extract Glabrous Sarcandra Herb Extract从肿节风Sarcandra glabra (Thunb.)中提取,已被用于治疗喉咙痛、脓肿甚至肿瘤。
E3880 Rhizoma Paridis Extract Rhizoma Paridis Extract从重楼Rhizoma paridis中提取,具有抗血管生成作用。
E3881 Swine'S Gallbladder Extract Swine'S Gallbladder Extract是从猪胆中提取的。
E3882 Swine'S Liver Extract 猪肝提取物是从猪肝中提取的。猪肝是一种有价值的食用屠宰副产品,适合人类食用。
E3883 Umbellate Pore Fungus Extract Umbellate Pore Fungus Extract从伞形毛孔菌中提取,具有化湿利尿的作用。
E3884 Galium Aparine Extract Galium Aparine Extract从猪殃殃Galium aparine中提取,可能对乳腺癌细胞具有潜在的抗癌作用,而不会损害正常的乳腺上皮细胞。
E3885 Swine‘S Pancreas Extract Swine'S Pancreas Extract是从猪胰子中提取的。
E3886 Bamboo Sap Extract Bamboo Sap Extract从竹汁中提取,用于皮肤、头发和指甲的保养。
E3887 Bamboo Shaving Extract Bamboo Shaving Extract提取自竹茹Bambusa,具有抗氧化活性。
E3888 Cortex Illicii Extract Cortex Illicii Extract是从具有心血管保护作用的追地风Ilicis Rotundae Cortex中提取的。
E3889 Cumin Extract Cumin Extract从孜然Cuminum cyminum L.中提取,是一种潜在的美白剂。
E3890 Lithospermum Erythrorhizon Extract Lithospermum Erythrorhizon Extract提取自紫草Lithospermum erythrorhizon,在支气管上皮细胞中具有抗炎反应。
E3891 Red Cabbages Extract Red Cabbages Extract从紫甘蓝Brassica oleracea L.中提取,不仅有助于治疗涉及血脂异常的疾病,还有助于治疗氧化应激。
E3892 Viola Philphica Munda Extract Viola Philphica Munda Extract从紫花地丁Viola philphica munda中提取,含有多糖和止痛剂(具有镇痛作用),是一种利尿剂。
E3893 Medicago sativa Extract Medicago sativa Extract提取自紫花苜蓿Medicago sativa L.,对皮肤细胞具有抗氧化和细胞毒性活性。
E3894 Ardisia Japonica Extract Ardisia Japonica Extract从紫金牛Ardisia japonica中提取,用于治疗咳嗽和止血。
E3895 Perilla Frutescens Extract Perilla Frutescens Extract从紫苏Perilla frutescens中提取,用作镇痛剂、抗流产剂和镇静剂。
E3896 Perilla Leaf Extract Perilla Leaf Extract从紫苏Perilla frutescens的叶子中提取,能够通过灭活病毒粒子来抑制 SARS-CoV-2 的复制。
E3897 Purple Perilla Seed Extract Purple Perilla Seed Extract萃取自紫苏Perilla frutescens L. Britt.的种子,支持肌肉合成和运动表现。
E3898 Radix Asteris Extract Radix Asteris Extract提取自紫菀Aster tataricus L. f.的根和根茎,已用于治疗咳嗽和哮喘。
E3899 Echinacea Extract (flower) Echinacea Extract (Flower)来源于紫锥花,即紫锥菊( Echinacea purpurea, Echinacea angustifoliaEchinacea pallida)的花朵。紫锥花用于治疗呼吸道感染和炎症,包括普通感冒、咳嗽、支气管炎和口咽炎症。
E3900 Echinacea Extract Echinacea Extract从紫锥菊Echinacea中提取,可增强免疫功能、缓解疼痛、减少炎症,并具有抗病毒和抗氧化作用.
E3901 Ribes Henryi Root Extract Ribes Henryi Root Extract是从钻骨风Ribes Henryi的根中提取的。
E3801 Morchella Extract Morchella Extract来自羊肚菌Morchella esculenta,具有抗氧化、免疫调节、抗癌和抗炎等应用前景。
E3802 Inula Cappa Extract Inula Cappa Extract提取自羊耳菊Inula Cappa,具有多种生物活性,具有抗炎、镇痛、抗菌、抗肿瘤、抗氧化、免疫调节等作用。
E3803 Goat Liver Powder Extract Goat Liver Powder Extract提取自羊肝。
E3804 Aspen Flower Extract Aspen Flower Extract提取自杨柳科植物Populus tomentosa Carr.或Populus canadensis Moench.的干燥花朵。
E3805 Psyllium Husk Extract Psyllium Husk Extract是从车前草Plantago ovata Forsk的种皮中提取的,车前草作为膳食纤维补充剂有很长的使用历史,以促进大肠功能的调节,最近它被证明可以降低血液胆固醇水平。
E3806 Allium Cepa Extract Allium Cepa Extract提取自洋葱Allium cepa Linnaeus,具有抗糖尿病、降血脂药和抗菌功能。
E3807 Chamomile Extract Chamomile Extract来自洋甘菊Matricaria chamomilla L.,除了对广泛性焦虑症和共病抑郁症患者具有抗焦虑活性外,它还可能产生临床意义上的抗抑郁效果。
E3810 Bauhinia Variegata Extract Bauhinia Variegata Extract是从洋紫荆Bauhinia Variegata中提取的,具有抗菌、抗氧化、抗炎和抗癌的作用。
E3700 Descurainiae Semen Lepidii Semen Extract Descurainiae Semen Lepidii Semen Extract从十字花科葶苈子sophia Descurainia (L.) Webb ex Prantl或Lepidium petalum wild.的干燥成熟种子中提取,具有抗炎、镇痛、解热、抗癌和抗氧化的特性,也用于治疗功能性便秘。
E3701 Phryma Leptostachya L. var. asiatica Hara Extract Phryma Leptostachya L. Var. Asiatica Hara Extract提取自透骨草Phryma leptostachya L. subsp. asiatica (Hara) Kitamura。
E3702 Eupolyphage sinensis Walker Extract Eupolyphage sinensis Walker Extract是从土鳖虫 eupolyyphaga sinensis Walker水提物中获取的,该提取物对小鼠的免疫反应有增强作用。
E3703 Talinum paniculatum Extract Talinum Paniculatum Extract来自土人参科土参Talinum Paniculatum (Jacq.)Gaertn,这是一种巴西塞拉多植物,用于传统医学和作为食物来源,具有利尿作用。
E3704 Rumex madaio Makino Extract Rumex Madaio Makino Extract从蓼科Rumex Madaio Makino中提取,其叶和根组织具有清热解毒、化瘀、排便杀虫等入药作用。
E3705 Smilax glabra Extract Smilax glabra Extract来源于土茯苓Smilax glabra Roxb,由于其显著的药理活性,在世界范围内被广泛用于治疗梅毒性溃疡、肢体高渗、病态白带、湿疹瘙痒、热性奇异症、痈毒和许多其他人类疾病。
E3706 Cortex pseudolaricis Extract Cortex Pseudolaricis Extract来自Pseudolarix amabilis Rehder的根皮,其中部分成分具有抗真菌活性、抗癌活性和过氧化物酶体增殖物激活受体活性等生物活性。
E3707 Chenopodium ambrosioides Extract Chenopodium Ambrosioides提取自Chenopodium Ambrosioides Linn. (藜科),具有杀虫作用和抗菌效力。
E3708 Cephaelis ipecacuanha Extract Cephaelis ipecacuanha Extract提取自茜草科吐根Psychotria ipecacuanhaCephaelis ipecacuanha的根部,其中含有催吐生物碱——吐根酚碱和吐根碱,除了作为催吐药,它还可用于多种丹方。
E3709 Lagotis glauca Extract Lagotis Glauca Extract提取自玄参科兔耳草Lagotis glauca Gaertn.。
E3710 Chinese Dodder Seed Extract Chinese Dodder Seed Extract来源于旋花科菟丝子Semen Cuscutae,在中医中作为补肾药物,用于治疗骨质疏松等衰老相关疾病。
E3712 Pisum sativum Extract Pisum Sativum Extract从豆科植物豌豆Pisum Sativum L.中提取,具有抗氧化、抗菌和降糖活性。
E3713 Vaccariae semen Extract Vaccariae semen Extract是从王不留行Vaccaria hispanica (Mill.) Rauschert的干燥成熟种子中提取的,用于治疗泌尿系疾病,如良性前列腺增生(benign prostatic hyperplasia, BPH)和泌尿系感染。
E3714 Clematis chinensis Extract Clematis Chinensis Extract来自毛茛科威灵仙Clematis chinensis Osbeck的干根,广泛用于各种关节炎相关疾病的治疗。
E3715 Crinum Asiaticum Extract Crinum Asiaticum Extract提取自文殊兰Crinum asiaticum L. var. sinicum (Roxb. ex Herb.) Baker,用于临床治疗抗炎、活血,尤其是紫癜、风湿关节痛、创伤性损伤,现在也用于治疗癌症。
E3716 Equisetum arvense Extract Equisetum arvense Extract是从木賊科木犀草Equisetum arvense L.中提取的,含有多种不同的化合物,具有保肝、抗氧化、抗糖尿病等作用。
E3717 Lactuca sativa Extract Lactuca Sativa Extract来自菊科莴苣Lactuca Sativa ,这种植物的种子用于缓解炎症和骨痛。
E3718 Glaucescent Fissistigma Root Extract Glaucescent Fissistigma Root Extract提取自番荔枝科乌骨藤Fissistigma glaucescens (Hance) Merr.根部,可能通过提高免疫功能而起到抗肿瘤作用。
E3719 Seed of Chinese Tallowtree Extract Seed Of Chinese Tallowtree Extract提取自乌桕Triadica sebifera L.的种子,这种种子的不同寻常之处在于其同时富含高度饱和脂肪和高度不饱和油,总脂类含量超过40%。
E3720 Oolong tea Extract Oolong Tea Extract来自半发酵的绿茶叶子,含有抗氧化剂,矿物质,维生素,多酚,咖啡因等物质,对健康有很多好处。
E3721 Fructus mume Extract Fructus mume Extract是从乌梅Fructus mume Sieb. et Zucc.的加工水果中获得的,可有效改善家族性阿尔茨海默病的认知障碍、东莨菪碱诱导的记忆障碍和慢性脑灌注不足诱导的认知障碍。
E3722 Zaocys dhumnades Extract Zaocys Dhumnades Extract提取自乌梢蛇 Zaocys dhumnades 的干燥成体,具有驱寒祛风、疏通经络、镇静等功效,主要用于治疗风湿、腿手麻木、截瘫、抽搐痉挛,以及中国等亚洲国家破伤风、麻风病螨病。
E3723 Lindera aggregata leaves Extract Lindera Aggregata Leaves Extract提取自乌药Lindera aggregate (Sims) Kosterm.的叶子,具有广泛的生物效应,包括抗氧化,抗菌,保护肝脏和心血管。
E3724 Ficus carica Extract Ficus Carica Extract源自桑科无花果Ficus Carica Linn,在传统医学中被用于治疗与消化、内分泌、生殖和呼吸系统有关的广泛疾病。
E3737 Passiflora caerulea Linnaeus Extract Passiflora caerulea Linnaeus Extract是从西番莲Passiflora caerulea L.中提取的,与Passiflora incarnate相比,Passiflora caerulea L.中含有更多的单胺氧化酶(MAO)抑制剂肉叶芸香碱。
E3738 Lycopersicon esculentum Miller Extract Lycopersicon Esculentum Miller Extract来自番茄Lycopersicon Esculentum Miller,具有强抗氧化和调节血脂的作用。
E3739 Panax quinquefolium Extract Panax Quinquefolium Extract是从西洋参Panax quinquefolium L.中提取的,其活性成分-人参皂苷-已被证明具有广泛的不同的生物活性,导致低血糖、抗炎、心脏保护和抗肿瘤的效果。
E3740 Isodon serra Extract Isodon Serra ExtractIsodon Serra提取自溪黄草Isodon Serra (Maxim.) Hara,具有抗肿瘤、抗血管生成、镇痛、抗结核、抗炎、抗菌和抗缺血活性。
E3741 Herba Siegesbeckiae Extract Herba Siegesbeckiae Extract提取自豨签草Herba Siegesbeckiae,具有多种化学成分和多种药理活性,是一种很有前途的药用植物。
E3742 SHILAJIT Asphaltum Extract Shilajit Asphaltum Extract源于Asphaltum punjabianum的渗出物,在传统的阿育吠陀医学体系中占有突出的地位。
E3744 Prunella Vulgaris Extract Prunella Vulgaris Extract来自夏枯草Prunella vulgaris,这种草药几个世纪以来一直被用于治疗感染和其他疾病。
E3746 hsian-tsao Extract Hsian-Tsao Extract从仙草(Mesona chinensis Benth.)中提取,仙草是一种兼有药用和食用功能的东方植物资源。
E3747 Agrimonia pilosa Extract Agrimonia pilosa Extract提取自仙鹤草Agrimonia pilosa Ledeb.,在治疗各种疾病方面,尤其是肠炎、胃溃疡和消化道出血方面,疗效显著。
E3748 Epimedium Extract Epimedium Extract是从淫羊藿Epimedium中提取的,初步证实淫羊藿对骨关节炎有抗骨质疏松和抗炎作用。
E3749 Curculigo orchioides Extract Curculigo orchioides Extract提取自石蒜科仙茅Curculigo orchioides Gaertn.,在中国传统医学和印度医学的诊所中用于治疗许多疾病,如骨质疏松症和妇科问题。
E3750 Opuntia dillenii Extract Opuntia Dillenii Extract是从仙人掌Opuntia Dillenii Haw (Nagphana)中提取的,传统上用于对抗炎症。
E3753 Coriander Extract Coriander Extract提取自香菜,可通过其挥发性物质影响脑电生理活动和唾液分泌,改善人的负面情绪。
E3754 Coriander Roots Extract Coriander Roots Extract来自于香菜Coriandrum sativum L.根部,具有预防癌症的潜力。
E3755 Cyperus Rotundus Extract Cyperus Rotundus Extract提取自香附子Cyperus Rotundus L.,具有植物化学,抗菌,抗氧化和抗遗传毒性的潜能。
E3756 Vetiveria Zizanioides Extract Vetiveria Zizanioides Extract来自香根草Vetiveria Zizanioides,这是一种药用植物,在肾脏相关疾病中具有多种治疗应用。
E3757 Shiitake Mushroom Extract Shiitake Mushroom Extract提取自Lentinula edodes
E3760 Cymbopogon Citratus Extract Cymbopogon Citratus Extract来自香茅Cymbopogon Citratus DC (Stapf.),具有抗菌、抗原虫、抗风湿、抗肿瘤、保护心脏、抗炎和保护胃的特性。
E3761 Elsholtzia Ciliata Extract Elsholtzia Ciliata Extract提取自唇形科香薷Elsholtzia Ciliata (Thunb.)Hyl,具有抗炎、抗病毒、抗菌、抗氧化、抗癌和血管舒张作用。
E3762 Amomum Extract Amomum Extract是生姜科植物的果实或种子,有极高的药用价值。
E3763 Sweet Potatoes Extract Sweet Potatoes Extract提取自香薯i>Ipomoea batata ,这是最有营养的亚热带和热带蔬菜之一。
E3765 Citrus Medica Extract Citrus Medica Extract提取自香橼Citrus medica (Citron),这是一种未被充分利用的水果植物,在植物的所有部分都有各种生物活性成分。
E3766 Feverfew Extract Feverfew Extract提取自小白菊Tanacetum parthenium L.,是一种用于预防偏头痛发作的草药。
E3767 Justicia Gendarussa Extract Justicia Gendarussa Extract是从小驳骨Justicia Gendarussa 中提取,在儿童哮喘,风湿病和腹绞痛中有效,也可能有潜力成为男性避孕药的基础成分。
E3768 Foeniculum Vulgare Extract Foeniculum Vulgare Extract是从伞形科小茴香Foeniculum vulgare中提取的,由于其抗氧化剂和植物雌激素化合物,被认为是伊朗传统用于改善生育力的物质。
E3769 Cirsium Setosum Extract Cirsium Setosum Extract来自小蓟Cirsium setosum,具有潜在的抗高血糖作用。
E3770 Wheat Germ Extract Wheat Germ Extract是从小麦胚芽中提取的,发酵的Wheat Germ Extract具有独特的抗癌特性。
E3771 Millet Extract Millet Extract来源于小米Finger millet,是膳食纤维和多酚的主要来源,对健康有多种益处,如抗糖尿病、抗氧化、低胆固醇、抗菌,并对饮食相关的慢性疾病有保护作用。
E3772 Eyebright Extract Eyebright Extract是从玄参科的小米草Herba Euphrasiae中提取的,具有抗炎、抗氧化、抗菌、抗癌、抗真菌、抗病毒、降压、保护皮肤、抗癫痫、抗卡他等活性。
E3774 Chlorella Pyrenoidosa Extract Chlorella Pyrenoidosa Extract是从小球藻Chlorella Pyrenoidosa中提取的,对VEGF诱导的新生血管有明显的抗血管生成活性和抗增殖活性。
E3775 Valeriana Officinalis Extract Valeriana Officinalis Extract是从缬草Valeriana Officinalis 的根部提取物,具有镇静和抗焦虑活性。
E3776 Allium Macrostemnon Extract Allium Macrostemnon Extract从薤白Allium macrostemon Bunge.中提取,其抗氧化活性、抗血小板聚集、血管舒张和抗抑郁类活性已被广泛证实。
E3780 Pleurotus eryngii Extract Pleurotus eryngii Extract来自杏鲍菇Pleurotus eryngii,可治疗神经系统疾病,如痴呆、阿尔茨海默氏症和帕金森病。
E3781 Bombyx Moril Extract Bombyx Moril Extract从雄蚕蛾 Bombyx mori中提取,对高胆固醇血症和动脉粥样硬化有显著作用,可能是由于其抗氧化和降血脂作用。
E3782 Arctostaphylos Uva Ursi Leaf Extract Arctostaphylos Uva Ursi Leaf Extract提取自熊果叶Arctostaphylos uva-ursi,可能是对抗痤疮丙酸杆菌Cutibacterium acnes毒力的天然产物,为寻常痤疮的治疗提供了一种新的治疗选择。
E3783 Spiraea Salicifolia Extract Spiraea Salicifolia Extract从绣线菊Spiraea Salicifolia中提取,对甲型和乙型流感病毒具有较强的抗病毒活性。
E3784 Cynanchum Paniculatum Extract Cynanchum Paniculatum Extract提取自徐长卿Cynanchum paniculatum (Bge.) Kitag. (CP),中药传统上用于治疗疼痛、关节炎、瘙痒、肿胀和疏血等症状。
E3785 Radix Dipsaci Extract Radix Dipsaci Extract是从续断Dipsacus asper中提取的,具有抗骨质疏松的功效。
E3786 Radix Scrophulariae Extract Radix Scrophulariae Extract来自玄参Radix Scrophulariae,具有抗凋亡和抗炎作用,可能通过影响丝裂原激活蛋白激酶(MAPKs)信号通路和抑制NF-κB通路发挥作用。
E3787 Flos Inulae Extract Flos Inulae Extract提取自旋复花Flos Inulae,具有抗突变、抗酪氨酸酶、抗炎等作用。
E3788 Smallanthus Sonchifolius Extract Smallanthus Sonchifolius Extract源自雪莲果Smallanthus Sonchifolius,具有抗菌、降糖、抗肥胖、抗癌和降低胆固醇的活性。
E3789 Saussurea Involucrata Extract Saussurea Involucrata Extract来自雪莲Saussurea involucrata Matsum. & Koidz.的花朵,在维吾尔和中医中,长期用于治疗类风湿关节炎、感冒咳嗽、胃痛、痛经、高原反应等。
E3790 Sambucus Adnata Extract Sambucus Adnata Extract从血满草Sambucus Adnata中提取,显示出显著的蛋白酪氨酸磷酸酶1B (PTP1B)抑制活性。
E3791 Surgentodoxa Cuneata Extract Surgentodoxa Cuneata Extract来自血藤Surgentodoxa Cuneata,具有抗炎、抗氧化、抗肿瘤、抗菌和抗败血症活性。
E3792 Lavandula Angustifolia Extract Lavandula Angustifolia Extract提取自薰衣草Lavandula angustifolia,对正常和阿尔茨海默病动物破伤风NMDA受体介导的突触传递均有积极影响。
E3793 Urtica Fissa Extract Urtica Fissa Extract是从荨麻科荨麻Urtica Fissa 中提取的,荨麻根是民族医学中治疗风湿病和荨麻疹的常用中药。
E3794 Brucea Javanica Extract Brucea Javanica Extract从鸦胆子Brucea Javanica的果实中提取,已被证明对肿瘤有效。
E3796 Flaxseed Extract Flaxseed Extract从亚麻籽Linum usitatissimum中提取,可调节MCF-7细胞生长,诱导细胞凋亡。
E3795 Commelina Communis Extract Commelina Communis Extract来自鸭跖草Commelina Communis,具有抑制NF-κB通路的抗炎作用,可用于治疗慢性炎症。
E3797 Butea Superba Extract Butea Superba Extract来自艳紫铆Butea Superba Roxb,这种植物被用于返老还童,提高性表现,或预防勃起功能障碍。
E3798 Avena Sativa L. Extract Avena Sativa L. Extract来自燕麦Avena Sativa L.的燕麦,具有很高的抗氧化性能。
E3799 Arrhenatherum Elatius Extract Arrhenatherum Elatius Extract提取于植物燕麦草Arrhenatherum elatius (L.) Pressl.。燕麦草具有去除土壤中重金属的能力。
E3800 Nidus Collocaliae Extract Nidus Collocaliae Extract从燕窝Nidus Collocaliae中提取,可能是通过抵抗血凝素而具有抗H5N1病毒的作用。
E3576 Semen celosiae Extract Semen Celosiae Extract是从青葙子Semen Celosiae中提取的。
E3577 Okra Extract Okra Extract是从秋葵Abelmoschus esculentus中提取的,具有降胆固醇、抗炎、抗氧化的作用。
E3579 Undaria pinnatifida Extract Undaria Pinnatifida Extract是从具有抗氧化活性的裙带菜Undaria Pinnatifida中提取的。
E3582 Ginseng leaf Extract Ginseng Extract是从人参Panax ginseng C. A. Meyer中提取的,对多种疾病具有预防和治疗作用。
E3583 Honeysuckle flower Extract Honeysuckle Flower Extract是从忍冬Hamamelis mollis的花中提取的。
E3584 Lonicera japonica vine Extract Lonicera Japonica Vine Extract提取自忍冬藤Lonicera Japonica Vine
E3585 Desertliving cistanche herb Extract Desertliving Cistanche Herb Extract是从肉苁蓉Cistanche deserticola中提取的,具有调节骨代谢的作用。
E3586 Myristica fragrans Extract Myristica Fragrans Extract是从具有自噬调节活性的肉豆蔻Myristica Fragrans中提取的。
E3587 Cinnamon Extract Cinnamon Extract是从肉桂Cinnamomum cassia中提取的,具有抗氧化活性。
E3588 Boswellia Extract Boswellia Extract是从乳香树Boswellia carterii 的树脂中提取的。
E3589 Evodia Lepta Bark Extract Evodia Lepta Bark Extract是从三叉苦Melicope pteleifolia的树皮中提取的,具有抗炎活性。
E3591 Common burreed tuber Extract Common burreed tuber Extract是从中药三棱(Sparganium stoloni erum,Buch. -Ham.) 中提取的,具有抗氧化特性。
E3592 Panax notoginseng Root Extract 三七根提取物是从三七Panax Notoginseng的根中提取的,通过MAPK介导的脂肪产热活化发挥对代谢综合征的保护作用。
E3590 Radix berberidis Extract Radix Berberidis Extract是从三颗针Berberis sargentiana中提取的。
E3593 Panax notoginseng Rhizoma Extract Panax Notoginseng Rhizoma Extract是从三七Panax Notoginseng的根茎中提取的,通过MAPK介导的脂肪产热活化发挥对代谢综合征的保护作用。
E3594 Radix tetrastigme Extract Radix Tetrastigme Extract是从三叶青Tetrastigma hemsleyanum中提取的,可调节TLR4/COX-2/NF-κB信号通路。
E3595 White mulberry root-bark Extract White Mulberry Root-Bark Extract是从桑Morus alba的根皮中提取的,可调节多种代谢途径,发挥降血糖作用。
E3596 Phellinus linteus Extract Phellinus Linteus Extract是从桑黄Phellinus Linteus中提取的,具有免疫调节作用。
E3597 Herba taxilli Extract Herba Taxilli Extract是从桑寄生Taxillus sutchuenensis中提取的,可用作HCV NS3丝氨酸蛋白酶的抑制剂。
E3598 Morus alba bark Extract Morus Alba Bark Extract是从桑Morus alba树皮中提取的,可调节多种代谢途径发挥降血糖作用。
E3599 Mantis egg-case Extract Mantis Egg-Case Extract是从螳螂Tenodera sinensisi Saussure的卵鞘中提取的。
E3600 Mulberry Extract Mulberry Extract是从桑Morus alba果实中提取的,可调节多种代谢途径发挥降血糖作用。
E3601 Mulberry Extract (leaves) Mulberry Extract (leaves)来源于传统中草药桑叶Morus alba L.。桑叶具有抗氧化、抗炎、抗糖尿病和抗肿瘤等多种生物学功能。
E3658 Double coptis chinensis Extract Double Coptis Chinensis Extract是从双黄连中提取的,具有解热消炎的作用。
E3689 Radix Asparagi Extract Radix Asparagi Extract提取于百合科植物天冬Asparagus cochinchinensis (Lour.) Merr.的干燥块根。因其高抗氧化活性而对炎症疾病有效。天冬提取物可以抑制蘑菇的褐变反应,类似于抗坏血酸。
E3690 Semiaquilegiae Radix Extract Semiaquilegiae Radix Extract是从天葵子Semiaquilegia adoxoides的块根中提取的。
E3691 Gastrodia Rhizome Extract Gastrodia Rhizome Extract来源于天麻Gastrodia elata Blume的根茎,在传统中草药中广泛用于治疗脑相关疾病(如头痛、偏头痛、头晕、癫痫、小儿惊厥、阿尔茨海默病、中风等)。
E3692 lucid asparagus Extract Lucid Asparagus Extract是从天门冬Asparagus cochinchinensis中提取的。
E3694 Geranium Extract Geranium Extract提取自天竺葵属天竺葵,可祛风燥湿,活血通络。
E3695 Hypericum japonicum Extract Hypericum Japonicum Extract是从田基黄 Hypericum japonicum 全草中提取的,已广泛用于治疗细菌性疾病、传染性肝炎、急慢性肝炎、胃肠道疾病、内出血和肿瘤。
E3696 Panax notoginseng Extract Panax notoginseng Extract是由三七Panax notoginseng的干根制成,用于治疗炎症和出血,也抑制酿脓链球菌Streptococcus pyogenes而不影响口腔共生细菌。
E3578 Fringed pink Extract Fringed Pink Extract是从具有抗炎活性的瞿麦Dianthus superbus中提取的。
E3139 Angelica Sinensis Extract Angelica Sinensis Extract提取自当归Angelica Sinensis (Radix Angelica Sinensis)的干燥根部,其对脑梗死的作用是通过多种途径实现的,包括抗关节硬化、改善微循环、抗血小板聚集、抗炎、抗氧化等作用。
E3169 Angelicae Pubescentis Radix Extract Angelicae Pubescentis Radix Extract是从独活Angelica biserrata的干燥根中提取的,是一种列入《中国药典》的抗风湿镇痛剂,常治疗风湿性关节炎和头痛。
E3171 Lamiophlomis Herba Extract Lamiophlomis Herba Extract是藏药独一味Lamiophlomis Rotata的水提物,具有止血作用。
E3172 Juniper Berry Extract Juniper Berry Extract是从杜松子(Juniperus communis L.)中提取的,可作为化学预防膳食剂,抑制细胞增殖和诱导细胞凋亡,从而减少结肠肿瘤的形成。
E3173 Eucommiae Cortex Extract 杜仲提取物是从原产于中国的稀有滋补药材杜仲(Eucommiae Cortex)树皮中提取的,对治疗高血压有很好的疗效。
E3175 Eucommia Ulmoides Male Flower Extract Eucommia Ulmoides Male Flower Extract是从杜仲Eucommia Ulmoides的雄花中提取的,具有降压作用。
E3176 Curcumae Rhizoma Extract Curcumae Rhizoma Extract 提取自中药莪术(Curcumae Rhizoma)。
E3177 Centipeda Minima Extract Centipeda Minima Extract是从药材鹅不食草(Centipeda Minima)中提取的,具有良好的抗癌活性。
E3178 Catechu Extract Catechu Extract是从儿茶(Areca catechu L.)中提取的,具有治疗多种疾病的潜力,尤其是寄生虫病、消化功能障碍和抑郁症。
E3181 Anona Squamosa Leaf Extract Anona Squamosa Leaf Extract是从 番荔枝Anona Squamosa的叶中提取的,对宫颈癌有抗癌活性。
E3182 Carica Papaya Fruit Extract Carica Papaya Fruit Extract从番木瓜(Carica Papaya)的果实中提取,已被证明具有抗蠕虫和抗阿米巴的活性。
E3183 Carica Papaya Leaf Extract Carica Papaya Leaf Extract是从番木瓜Carica papaya的叶子中提取的,具有抗癌、抗炎、抗糖尿病和抗病毒活性。
E3184 Solanum Lycopersicum Extract Solanum Lycopersicum Extract 从番茄(Solanum Lycopersicum)中提取,可用于治疗心血管疾病、神经系统疾病,并可作为抗氧化剂、抗癌剂和抗菌剂。
E3185 Psidium Guajava Extract Psidium Guajava Extract是从番石榴Psidium Guajava中提取的,已被用于治疗糖尿病、心血管疾病、癌症和寄生虫感染。
E3186 Sennae Folium Extract Sennae Folium Extract 提取自中药番泻叶(Sennae Folium)。
E3187 Descolor Cinquefoil Herb Extract Descolor Cinquefoil Herb Extract是从翻白草Potentilla中提取的,具有抗糖尿病功效,可能对提高葡萄糖摄取有有益作用。
E3188 Cissus Quadrangularis Extract Cissus Quadrangularis Extract is extracted from Cissus quadrangularis, which is used in the treatment of osteoporosis, asthma, haemorrhoids, and menstrual disorders.
E3189 Saposhnikoviae Radix Extract Saposhnikoviae Radix Extract 提取自中药防风(Saposhnikoviae Radix)。
E3190 Stephaniae Tetrandrae Radix Extract Stephaniae Tetrandrae Radix Extract从防己Stephaniae Tetrandrae Radix中提取,用于治疗水肿、排尿困难和风湿。
E3191 Euphorbia Hirta Extract Euphorbia Hirta Extract是从飞扬草Euphorbia Hirta中提取的,用于治疗胃肠道疾病。
E3193 Saponaria Officinalis Extract Saponaria Officinalis Extract 从肥皂草Saponaria Officinalis 中提取,通过破坏TLR4/MD2 复合物和阻断MyD88 依赖性炎症信号传导来减少下游炎症反应。
E3194 Torreyae Semen Extract Torreyae Semen Extract是从香榧(Torreya grandis)的种子中提取的,可用于治疗肠道寄生虫。
E3195 Combretum alfredii Hance Extract Combretum alfredii Hance Extract是从风车子(Combretum alfredii Hance)中提取的。
E3198 Kadsura Longipedunculata Ratan Extract Kadsura Longipedunculata Ratan Extract是从风沙藤Kadsura Longipedunculata Ratan中提取的,具有中等的保肝活性。
E3227 Uncaria Extract Uncaria Extract从钩藤Uncaria中提取,用于治疗高血压、发烧、头痛、胃肠道疾病和真菌感染。
E3228 Cynodon Dactylon Extract Cynodon Dactylon Extract从狗牙根Cynodon Dactylon中提取,具有伤口愈合特性和抗氧化活性。
E3229 Lycii Fructus Extract Lycii Fructus Extract是从枸杞Lycium barbarum的果实中提取的,具有很高的抗氧化能力。
E3230 Eriocauli Flos Extract Eriocauli Flos Extract是从谷精草Eriocauli Flos中提取的,用于治疗眼科疾病,包括糖尿病视网膜病变。
E3231 Setariae Fructus Germinatus Extract Setariae Fructus Germinatus Extract提取自谷芽Setariae Fructus Germinatus,已知对肝脏疾病有显著影响。
E3232 Rhizoma Drynariae Extract Rhizoma Drynariae Extract提取自中药骨碎补(Rhizoma Drynariae)。
E3233 Trichosanthis Fructus Extract Trichosanthis Fructus Extract从瓜蒌Trichosanthis Fructus中提取,用于治疗胸梗阻、心绞痛、心力衰竭、心肌梗死、肺心病和一些脑缺血疾病。
E3234 Trichosanthis Pericarpium Extract Trichosanthis Pericarpium Extract从瓜蒌皮Trichosanthis Pericarpium中提取,能够通过调节PI3K/Akt/NO通路保护心肌细胞免受缺氧/复氧损伤。
E3235 Hypericum Perforatum Extract Hypericum Perforatum Extract是从贯叶连翘(Hypericum Perforatum)中提取的,具有抗血小板特性。
E3236 Champion Wood Fern Extract Champion Wood Fern Extract提取自贯众Dryopteris Championii,具有抗菌活性。
E3237 Euonymus alatus Sieb Extract Euonymus alatus Sieb Extract从鬼箭羽Euonymus alatus Sieb中提取,可协同低密度胰岛素提高脂肪细胞的葡萄糖摄取率。
E3238 Bidens Bipinnata Extract Bidens Bipinnata Extract从鬼针草Bidens Bipinnata L中提取,在传统医学中用于治疗各种炎症。
E3239 Osmanthus Extract Osmanthus Extract从桂花(Osmanthus fragrans)中提取,具有神经保护、自由基清除和抗氧化作用,也是天然抗衰老化合物的良好来源。
E3240 Longan Extract Longan Extract是从龙眼(Dimocarpus longan)中提取的,龙眼具有抗氧化、抗增殖、降血糖和降尿酸的作用。
E3241 Cinnamomi Ramulus Extract 桂枝提取物是从桂枝(Cinnamomi Ramulus)中提取的,可通过Akt/ERK信号通路抑制结肠癌细胞的生长。
E3242 Gecko Extract Gecko Extract是从蛤蚧(Gekko gecko)中提取的。
E3243 Pinus Pinaster Bark Extract Pinus Pinaster Bark Extract从海岸松Pinus Pinaster的树皮中提取,具有抗炎作用。
E3244 Laminaria Japonica Extract Laminaria Japonica Extract是从海带Laminaria Japonica中提取的,有助于预防肥胖和糖尿病。
E3245 Piperis Kadsurae Caulis Extract Piperis Kadsurae Caulis Extract提取自海风藤,能够降低细胞中 IL-1β 和 TNF-α 的表达水平。
E3246 Lygodii Spora Extract Lygodii Spora Extract是从海金沙Lygodium japonicum的孢子中提取的,具有抗雄激素和促进头发生长的活性。
E3247 Hainan Nightshade Fruit Extract Hainan Nightshade Fruit Extract是从海南茄Hainan Nightshade的果实中提取的,具有增强免疫力和消除疼痛的作用,因为它可以减少体内的炎症和肿胀。
E3248 Oriental Variegated Coralbean Bark Extract Oriental Variegated Coralbean Bark Extract提取自海桐皮(Aralia chinensis L.),可预防心肌缺血/再灌注损伤,减少钙稳态失衡和ERS相关的细胞凋亡。
E3299 Polygonum Cuspidatum Extract Polygonum Cuspidatum Extract是从虎杖(Reynoutria japonica Houtt)中提取的。
E3300 Pericarpium Zanthoxyli peel Extract Pericarpium Zanthoxyli Peel Extract是花椒皮浸膏,主要含有挥发油、生物碱、酰胺类物质,其他成分有香豆素、木质素、脂肪酸、类黄酮等,另外还有少量氨基酸和矿物质。
E3301 Peanut hull Extract Peanut Hull Extract是花生壳提取物,其中含有丰富的黄酮类色素,以贰元形式存在较多,可用于开发天然黄色素。
E3302 Peanut seed coat Extract Peanut Seed Coat Extract是花生种皮的提取物,含有丰富的生物活性成分,对防治化疗所致血小板减少症有生理作用。
E3303 Achyranthes bidentata Blume root Extract Achyranthes Bidentata Blume Root Extract源自牛膝根 Achyranthes bidentata的干燥根部,对高脂饲料喂养大鼠具有抑制脂肪生成和控制体重的作用。
E3304 Sophora japonica fruit Extract Sophora Japonica Fruits Extract (Fructus Sophorae Extract, Rexflavone)源自槐树Sophora japonica的果实,含有丰富的异黄酮类成分,也是一种具有显著改善绝经指数的保健功能性食品成分。
E3305 Sophora Flower Extract Sophora Flower Extract源自槐树Sophora japonica的干花,在中国、日本和韩国用于治疗呕血和痔疮出血。
E3306 Phellodendron amurense bark Extract Phellodendron Amurense Bark Extract (Nexrutine)源自黄柏Phellodendron amurense的树皮,在体内外均显示出良好的前列腺癌治疗作用。
E3308 Daylily Flower Extract Daylily Flower Extract源自黄花菜Hemerocallis citrina的花朵和花蕾部位,具有神经保护作用。
E3309 Polygala Fallax Hemsl. Rhizome Extract Polygala Fallax Hemsl. Rhizome Extract提取自Polygala Fallax Hemsl.的根部,其对免疫功能产生影响,具有抗应激、抗炎、活血、调脂、对乙肝病毒体外抑制等作用。
E3310 Brassica Juncea Seed Extract Brassica juncea seed Extract提取自芥菜Brassica juncea L.种子,通过显著降低TNF-α和IL-6的表达水平,逆转DNA遗传毒性,从而在硫代乙酰胺诱导的急性肝衰竭实验动物模型中发挥保护/治疗作用。
E3311 Rhizoma polygonati root Extract Rhizoma polygonati Extract源自黄精Rhizoma polygonati的根部,历史悠久,含有多种化学成分,具有抗癌、抗衰老、抗糖尿病、抗疲劳、预防疾病等作用,或作为食品中的营养来源。
E3312 Rhizoma Coptidis Root Extract Rhizoma Coptidis Root Extract源自毛茛科药用植物黄连Rhizoma coptidis的干燥根部,已被中医使用了2000多年。
E3313 Rhizoma Coptidis Fibrous Root Extract Rhizoma Coptidis Fibrous Root Extract是从黄连(Rhizoma Coptidis)须根中提取的。
E3315 Astragalus rhizome Extract Astragalus Rhizome Extract源自黄芪Radix Astragali的根部,主要成分为多糖、黄酮类化合物、皂苷、氨基酸和微量元素,具有抗炎、免疫调节、抗氧化、抗癌等作用。
E3316 Scutellariae rhizome Extract Scutellariae Rhizome Extract源自黄芩Scutellaria baicalensis的根茎,以黄芩苷为主要成分,长期以来在中国、日本、韩国作为传统药物和功能食品,用于治疗炎症、发热、肝炎、过敏性疾病、高血压等疾病。
E3317 Okra fruit Extract Okra fruit extract (Abelmoschus esculentus fruit extract)源自黄秋葵Abelmoschus esculentus的果实,由于其各种药用特性,如抗糖尿病、抗氧化、抗疟、抗菌、抗癌、镇痛、止泻和抗炎等特性,被用作替代治疗。
E3318 Cistus Incanus Extract Cistus incanus Extract源自地中海灌木植物Cistus incanus L.,含有丰富的多酚类化合物,具有显著的抗氧化活性,可能是化妆品工业的有效活性成分。
E3322 Agastache rugosa Extract Agastache rugosa Extract是从藿香(Agastache rugosa )中提取的。
E3323 Plumeria Rubra Extract Plumeria Rubra Extract是从用于治疗心血管疾病的鸡蛋花Plumeria Rubra中提取的。
E3324 Herba Abri Extract Herba Abri Extract是从鸡骨草Herba Abri 中提取的,用于治疗急性或慢性肝炎和乳腺炎。
E3325 Croton Crassifolius Geisel. Extract Croton Crassifolius Geisel. Extract是从鸡骨香Crassifolius Geisel中提取的,具有抗血管生成成分,可用于癌症治疗。
E3326 Gizzard pepsin Extract Gizzard pepsin Extract是从家鸡( Gallusgallusdomesticus Brisson)的干燥沙囊中提取的。
E3327 Chinese Fevervine Herb Extract Chinese Fevervine Herb Extract是从鸡屎藤Paederia foetida中提取的,用于治疗炎症、痔疮和腹泻。
E3328 Suberect spatholobus stem Extract Suberect spatholobus stem Extract 从中药鸡血藤(Suberect spatholobus)中提取,可抑制TGF-β1/p38MAPK信号通路和ColⅠ的合成,从而起到治疗肝纤维化的作用。
E3329 Centella Asiatica Extract Centella Asiatica Extract是从积雪草Centella Asiatica中提取的,对TNF-α有抑制作用,可作为特应性皮炎的治疗剂。
E3330 Agaricus blazei Extract Agaricus blazei Extract从姬松茸Agaricus blazei Murill中提取,被认为具有抗肿瘤和抗氧化活性。
E3331 Impatiens Balsamina L. Extract Impatiens Balsamina L. Extract是从急性子Impatiens Balsamina L.中提取的,通过降低局部皮肤组织中的雄激素含量,对雄激素性脱发具有治疗作用。
E3333 Viburnum Dilatatum Extract Viburnum Dilatatatum Extract从荚蒾Viburnum Dilatatatum中提取,具有α-葡萄糖苷酶抑制活性和降血糖作用。
E3334 Bacopa monniera Extract Bacopa monniera Extract是从假马齿苋Bacopa monniera中提取的,几个世纪以来,一直被用作传统的阿茹吠陀药物,用于治疗记忆和炎症。
E3335 Curcuma longa Extract Curcuma longa Extract是从姜黄(Curcuma longa)中提取的。
E3337 Larva of a Silkworm with Batrytis Extract Larva Of A Silkworm With Batrytis Extract是从蚕Bombyx的幼虫中提取的,用于治疗过敏性鼻炎。
E3338 Lignum Dalbergiae odoriferae Extract Lignum Dalbergiae Odoriferae Extract是从降香Lignum Dalbergiae Odoriferae中提取的,用于治疗活血、增加冠状动脉血流量、抗氧化、抗炎、抗肿瘤。
E3339 Malt Extract Malt extract是从麦芽Hordeum vulgare中提取的,它富含可溶性纤维,通过优化好细菌和减少坏细菌来帮助改善消化。
E3341 Hawthorn Extract Hawthorn Extract从焦山楂Crataegus中提取,具有降血压、降血脂、降血糖、抗焦虑、免疫调节、抗诱变等药理活性。
E3342 Carob Bean Extract Carob Bean Extract是从角豆Ceratonia siliqua的豆类中提取的,用于治疗心血管和胃肠道疾病。
E3343 Gynostemma pentaphyllum Extract Gynostemma Pentaphyllum Extract源自绞股蓝Gynostemma pentaphyllum全草,通过上调C2C12骨骼肌中PGC-1α,促进肌管分化和线粒体代谢,提高运动性能。
E3344 Yeast extract Yeast Extract是从酵母中提取的,有助于提高能量,增强免疫系统,以及葡萄糖敏感性。
E3345 ElderBerry Extract ElderBerry Extract是从接骨木Sambucus 的浆果中提取的,传统上被用于预防和治疗呼吸问题。
E3346 Oriental Paperbush flower Extract Oriental Paperbush flower Extract是从结香Edgeworthia chrysantha的花中提取的,可能是治疗骨质疏松等骨质溶解性疾病的潜在药物。
E3347 Mustard Extract Mustard Extract从芥菜Brassica juncea中提取,有助于缓解压力和抑郁。
E3348 Capsella bursa-pastoris Extract Capsella Bursa-Pastoris Extract是从荠Capsella Bursa-Pastoris中提取的,有助于退烧,改善视力和镇静肝脏。
E3349 Broccoli Extract Broccoli Extract是从芥兰Brassica oleracea var. italica中提取的,具有抗诱变的特性。
E3350 Goodyera kwangtungensis Tso. extract Goodyera kwangtungensis Tso. Extract取自金边莲Goodyera kwangtungensis C.L. Tso,整株植物用于改善肺部状况和清痰。
E3351 Abrus mollis Extract Abrus mollis Extract从鸡骨草Abrus mollis中提取,是一种民间饮料和汤,有净化肝脏毒素、预防肝脏疾病的作用。
E3352 Radix Tinosporae Extract Radix Tinosporae Extract从金果榄Radix Tinosporae中提取,是一种治疗各种炎症性疾病的中药。
E3353 Acacia Farnesiana Extract Acacia Farnesiana Extract是从金合欢Acacia Farnesiana中提取的,它对结核分枝杆菌和痢疾细菌有作用。
E3574 Cyclocarya paliurus Extract Cyclocarya Paliurus Extract是从青钱柳Cyclocarya Paliurus中提取的,具有抗纤维化活性。
E3307 Soybean Extract Soybean Extract源自黄豆的果实,可以调节视黄酸相关基因,并显示出光保护作用,这表明其可能是一种可以在阳光下安全使用的抗衰老成分。
E3122 Arecae Pericarpium Extract Arecae Pericarpium Extract是从大腹皮Arecae Pericarpium中提取的,可用于治疗胃食管反流病。
E3124 Cirsii Japonici Herba Extract Cirsii Japonici Herba Extract提取自大蓟Cirsii Japonici,可用于治疗慢性肾小球肾炎。
E3125 Hordeum Vulgare Extract Hordeum Vulgare Extract是从大麦(Hordeum vulgare)中提取的,其减少脂质的吸收是抗肥胖作用的基础。
E3126 Rice Extract Rice Extract是从大米(Oryza sativa)中提取的,具有预防绝经后妇女脂肪肝的功效。
E3128 Isatidis Folium Extract Isatidis Folium Extract从大青叶Isatis indigotica Fort. (十字花科)的干叶子中提取,作为解热、抗病毒、消炎、抗流感和抗癌剂,在东方国家已普遍应用了几个世纪。
E3130 Garlic Extract Garlic Extract是从大蒜(Allium sativum)中提取的,具有抗高血压、抗高血脂、降血糖的作用。
E3131 Jujubae Fructus Extract Jujubae Fructus Extract是从大枣Ziziphus jujuba Mill的果实中提取的,对慢性便秘和2型糖尿病有有效的治疗作用。
E3132 Citrus Aurantium Flower Extract Citrus Aurantium Flower Extract是从代代花(Citrus Aurantium)中提取的,主要用于治疗消化问题。
E3134 Sphaeranthus Africanus Extract Sphaeranthus Africanus Extract从戴星草Sphaeranthus africanus中提取,其中Carvotacetone类化合物具有抗分支杆菌作用。
E3135 Salvia Miltiorrhiza Extract Salvia Miltiorrhiza Extract从丹参Salvia miltiorrhiza (唇叶科)中提取,含有丰富的丹参酮I、丹参酮II、丹参新酮和丹酚酸等多种化合物,其中尤以丹参根为甚,具有抗氧化、抗微生物、抗病毒、抗癌、抗炎、心血管疾病等药理活性。
E3137 Fermented Soybean Extract Fermented Soybean Extract是从发酵大豆中提取的,具有较高的抗氧化活性。
E3138 Lophatheri Herba Extract Lophatheri Herba Extract提取自淡竹叶Herba Lophatheri,可增强壳聚糖膜的耐水耐油性,壳聚糖膜的抑菌活性随时间的推移而下降。
E3141 Codonopsis Pilosula Extract Codonopsis Pilosula Extract提取自党参Codonopsis pilosula,不仅对正常黑素细胞有抗黑素作用,而且通过诱导自噬和小眼相关转录因子(MITF)表达,对氧化应激的黑素细胞有细胞保护作用。
E3142 Semen Canavaliae Extract Semen Canavaliae Extract是从刀豆(Canavalia Gladiate)中提取的,它是一种天然的抗氧化剂和抗菌剂,具有潜在的健康益处以及在食品工业中的应用。
E3143 Ground Ginseng Extract Ground Ginseng Extract提取自唇形科地笋属植物硬毛地参(Lycopus lucidus var. hirtus Regel)的干燥根茎。
E3145 Kochiae Fructus Extract Kochiae Fructus Extract从地肤子Kochia scoparia (L.) Schrad.中提取,由于具有抗炎、抗糖尿病、杀虫、抗过敏、止痒、抗类风湿性关节炎等药理活性而受到广泛关注。
E3146 Sweet Potato Root Extract Sweet Potato Root Extract是从地瓜根(Ipomoea batatas)中提取的,它是一种极好的新型天然促健康物质的来源,例如β-胡萝卜素和花青素。
E3148 Euphorbiae Humifusae Herba Extract Euphorbiae Humifusae Herba Extract从地锦草Euphorbiae Humifusae中提取,可诱导Hep3B肝癌细胞凋亡,可用于治疗肝癌。
E3149 Pheretima Extract Pheretima Extract 从地龙Pheretima中提取,对哮喘、咳嗽、发烧等多种炎症性疾病有疗效。
E3150 Dinian Herb Extract Dinian Herb Extract是从地菍Melastoma dodecandrum中提取的,具有调节餐后血糖的作用。
E3151 Sanguisorbae Radix Extract Sanguisorbae Radix Extract是从地榆Sanguisorbae Radix中提取的,它通过抑制PD-1/PD-L1而具有抗癌作用,同时也增强了免疫肿瘤作用。
E3152 Junci Medulla Extract Junci Medulla Extract从灯芯草Junci Medulla中提取,促进排尿,滤除湿气,解除疼痛的尿功能障碍,冷却血液,止血。
E3153 Corchorus Olitorius Extract Corchorus olitorius Extract是从帝王菜(Corchorus Olitorius)的叶子中提取的,具有抗炎、抗氧化、抗癌和保肝作用。
E3156 Clitoria Ternatea Flower Extract Clitoria Ternatea Flower Extract是从蝶豆花Clitoria Ternatea中提取的,具有抗氧化和抗菌性能。
E3157 Erycibes Caulis Extract Erycibes Caulis Extract 从丁公藤Erycibes Caulis中提取,用于治疗类风湿性关节炎。
E3158 Caryophylli Flos Flower Extract Caryophylli Flos Flower Extract是从丁香Caryophylli Flos的花中提取的,可用于治疗糖尿病足溃疡的治疗,因为它能促进糖尿病伤口愈合,并具有抗菌活性。
E3159 Caryophylli Flos Extract Caryophylli Flos Extract提取自丁香Caryophylli Flos,对野生型SARS-CoV和HIV/SARS-CoV S伪病毒感染有抑制作用,在病毒分别为30.3±2.6 μg/mL和58.8±5.6 μg/mL,抑制效果中等(IC50<100 μg/mL),。
E3162 Wax Gourd Peel Extract Wax Gourd Peel Extract是从冬瓜(Benincasa hispida)的果皮中提取的,用于防治高脂血症、高血糖症、肥胖症、心血管疾病等代谢性疾病。
E3163 Wax Gourd Seed Extract Wax Gourd Seed Extract是从冬瓜(Benincasa hispida)的果实中提取的,具有抗炎、心血管、保肝作用,对乳腺癌细胞具有细胞毒性。
E3164 Malvae Fructus Extract Malvae Fructus Extract是从冬葵子(锦葵Malvae Fructus的种子)中提取的,具有通脉利水消肿、干脓、止泻、止渴的作用,用于治疗坐骨和膀胱结石。
E3165 Rabdosiae Rubescentis Herba Extract Rabdosiae Rubescentis Herba Extract提取自唇形科冬凌草Rabdosia rubescens (Hemsl.) Hara的地上干燥部分,具有抗菌、抗寄生虫、抗炎、抗癌等多种生物活性。
E3168 Bean Sprout Extract Bean Sprout Extract是从豆芽菜(蚕豆faba的发芽豆)中提取的,有助于缓解焦虑和轻度抑郁。
E3034 Cynanchi Atrati Extract Cynanchi Atrati Extract是从白薇Cynanchi atrati Radix中提取的,传统上用作抗炎剂,具有抑制IKK介导的NF-κB激活的潜力,具有调节炎症或癌症条件的价值。
E3035 Dittany Bark Extract Dittany Bark Extract从白藓Dittany的皮中提取,常用于治疗炎症、细菌和真菌感染,减轻炎症和消化健康。
E3037 Solanum lyratum Extract Solanum lyratum Extract (300 μg/ml)可以增加Bax水平,降低Bcl-2的水平,导致线粒体膜电位(Δæm)丢失,细胞色素C释放,caspase-9和-3激活,最终导致细胞凋亡。Solanum lyratum Extract (300 μg/ml)还促进p53和p27分泌,但降低cyclin B1水平,从而导致S期阻滞。
E3038 White Kidney Bean Extract White kidney bean extract是从白芸豆Phaseolus vulgaris L.中提取的,对体重和代谢健康有有益作用。
E3039 Angelica Root Extract Angelica Root Extract源自白芷Angelica dahurica的根部。
E3040 Stemonae Extract Stemonae Extract从百部Radix Stemonae的根茎中提取,作为一种口服镇咳药,在中医中已有几千年的历史,具有镇咳、抗结核、抗菌、抗真菌、抗寄生虫等药理作用。
E3042 Lily Bulbs Extract Lily Bulbs Extract是从百合Lilium brownii var.中提取的。
E3043 Thymus Serpillum Extract Thymus Serpillum Extract是从百里香Thymus serpyllum中提取的,是一种芳香类药用植物,具有多种生物学特性,包括抗癌活性。
E3044 Passion Fruit Extract Passion Fruit Extract是从百香果Passiflora edulis Sims中提取的。
E3045 Chinese Arborvilea Seed Extract Chinese Arborvilea Seed Extract提取自侧柏Platycladus orientalis (L.)Franco的干燥成熟种仁,具有明显的抗焦虑作用,其作用机制可能与增加海马组织γ-氨基丁酸(GABA)的水平和降低谷氨酸(Glu)的水平有关。
E3047 Isatis Extract Isatis Extract提取自板蓝根Baphicacanthus cusia,可能能够抵抗引起感染的细菌和病毒,降低发烧和肿胀,也可能阻止癌细胞繁殖。
E3048 Chestnut Extract Chestnut Extract从板栗Castanea Sativa中提取,可用于治疗慢性静脉功能不全(CVI)。
E3049 Lobeliae Chinensis Extract Lobeliae Chinensis Extract是从半边莲Lobeliae Chinensis中提取的,是一种广泛用于治疗糖尿病的中草药,被发现具有抑制DPP4的降糖机制。
E3051 Scutellaria Barbata Extract Scutellaria Barbata Extract提取自半枝莲Scutellaria barbataScutellaria barbata纳米粒子(Sb-AgNP)能有效抑制生物膜的形成,对皮肤感染引起的微生物具有抗菌作用。
E3046 Patriniae Extract Patriniae Extract提取自败酱草Patrinia scabiosaefoliaPatrinia villosa,能够显著减少Pseudomonas aeruginosa的生物膜形成,并显著改变成熟生物膜的结构。
E3052 Cabbage Extract Cabbage extract是从包心菜Brassica oleracea var. capitata中提取的,对葡萄糖稳态有多靶点调节作用,有助于预防和治疗2型糖尿病。
E3053 Mentha Arvensis Leaf Extract Mentha Arvensis Leaf Extract是从薄荷Mentha Arvensis叶中提取的,与合成的GSNPs联合使用可能是一种很有前景的抗乳腺癌药物,因为它们毒性小,无诱变作用,并介导caspase 9-依赖性凋亡。
E3054 Primula Malacoides Extract Primula Malacoides Extract提取自报春花科的Primula Malacoides全草。
E3055 Rhizoma Menispermi Extract Rhizoma Menispermi Extract是从北豆根Menispermum dauricum DC中提取的,具有显著的抗癌、抗缺氧等生物活性。
E3056 Coasial GIehnia Root Extract Coasial GIehnia Root Extract从北沙参Glehnia littoralis Fr. Schmidt ex Miq.(伞形科)干燥的根中提取。
E3059 Piper longum Extract Piper longum Extract是荜茇Piper longum根的水提物,有望预防高血糖、心血管、肝脏和肾脏疾病。
E3060 Dioscorea Sativa Extract Dioscorea Sativa Extract提取自薯蓣科植物萆薢Dioscorea septemloba ThunbtDioscorea hypoglauca Palibin的干燥根茎。
E3064 Polygonum Aviculare Extract Polygonum Aviculare Extract提取自萹蓄Polygonum Aviculare,对MCF-7乳腺癌细胞有较强的细胞增殖抑制作用,诱导凋亡细胞死亡。
E3065 Lentil Extract Lentil Extract来自扁豆Lens culinaris,可能对帕金森病患者的紧张症有效。
E3066 Miraclefruit Extract Miraclefruit Extract是从便秘果(Synsepalum dulcificum)中提取的,它具有降低胆固醇水平的潜力,是降胆固醇剂的天然来源。
E3067 Trionycis Carapax Extract Trionycis Carapax Extract提取自鳖甲Carapax Trionycis,其中分子量小于6 kd (CT6)的Carapax Trionycis提取物可下调TGF-β1诱导的HSC-T6细胞系中TNF-α, IL-1β and IL-6的表达,提示其对肝纤维化有潜在的治疗作用。
E3069 Spinach Extract Spinach Extract从菠菜Spinacia oleracea中提取,对肠道菌群和SCFAs有有益作用。
E3071 Malaytea Scurfpea Extract Malaytea Scurfpea Extract是从补骨脂Psoralea corylifolia L.中提取的,具有抗真菌活性,对病原体具有防御作用。
E3072 Paniculata Extract Paniculata Extract是从中药布渣叶(Microcos paniculata L.)中提取的,具有多种生物学功能,包括抗氧化活性和α-葡萄糖苷酶抑制作用。
E3073 Silkworm Chrysalis Extract Silkworm Chrysalis Extract是从蚕bombyx mori茧的蚕蛹中提取而成。
E3074 Xanthium Sibiricum Extract Xanthium Sibiricum Extract从 Xanthium Sibiricum中提取,具有抗炎活性。
E3075 Atractylodis Rhizoma Extract Atractylodis Rhizoma Extract提取自白术Atractylodes macrocephala,有治疗脾虚食欲不振、腹胀腹泻、痰饮头晕心慌、水肿、胎动不安等作用。
E3076 Brown Rice Extract Brown Rice Extract是从糙米(Oryza sativa)中提取的,它具有有效的抗氧化活性,可缓解导致心力衰竭的因素,例如高血压和糖尿病。
E3077 Tsaoko Fructus Extract Tsaoko Fructus Extract是从草果Tsaoko Fructus中提取的,具有抗菌作用。
E3078 Sarcandra Glabra Extract Sarcandra Glabra Extract提取自草珊瑚Sarcandra glabra,是一种著名的草药,传统上被用作凉茶或食品补充剂,在中国用于提高精神效率,缓解压力或疲劳。
E3080 Platycladi Cacumen Extract Platycladi Cacumen Extract提取自侧柏叶Platycladi Cacumen,传统上用于抗脱发和促进头发生长。
E3081 Tea Seed Extract Tea Seed Extract是从茶籽(Camellia oleifera)中提取的,具有有效的抗肿瘤活性。
E3082 Bupleurum Extract Bupleurum Extract从柴胡Bupleurum中提取,用于炎症治疗。
E3083 Cicada Slough Extract Cicada Slough Extract从蝉蜕Cicada Slough中提取,可缓解呼吸道疾病的早期或轻微症状,缓解皮疹,眼睛和喉咙不适。
E3084 Hedera Helix Extract Hedera Helix Extract从常春藤Hedera Helix中提取,可安全用于急性URTIs和支气管炎引起的咳嗽。
E3085 Dichroae Radix Extract Dichroae Radix Extract提取自常山Dichroae radix,在中医中作为抗疟、祛痰、解热的药物治疗中具有良好的临床疗效,对球虫病感染的鸡单独使用或作为主要中药复方均有抗球虫作用。
E3086 5% Artichoke Leaf EXTRACT 5% Artichoke Leaf EXTRACT 提取自朝鲜蓟(Cynara scolymus),具有抗氧化、利胆、保肝、增强胆汁和降脂作用。
E3087 Artichoke Extract Artichoke Extract是从朝鲜蓟Cynara cardunculus var. scolymus中提取的,具有抗氧化、利胆、保护肝脏、增强胆汁和降脂的作用。
E3088 Plantaginis Herba Extract Plantaginis Herba Extract是从车前草科植物的干燥全株中提取的,在中医中以促进排尿、治小便涩痛而闻名。
E3089 Plantaginis Semen Extract Plantaginis Semen Extract提取自车前子Plantaginis Semen,具有显著的抗高尿酸血症、抗炎、保护肾脏作用,并通过调节脂质代谢紊乱来减弱氧酸钾诱导的高尿酸血症。
E3090 Aquilariae Lignum Resinatum Extract Aquilariae Lignum Resinatum Extract提取自沉香Aquilariae Lignum Resinatum (瑞香科)的干燥根茎,被广泛用于治疗呕吐、胃痛和胃肠功能障碍。
E3091 Citri Reticulatae Pericarpium Extract Citri Reticulatae Pericarpium Extract提取自陈皮Citri Reticulatae Pericarpium,富含多甲氧基类黄酮,具有显著的抗炎、抗氧化和抗凋亡活性,被认为是治疗代谢紊乱和循环系统疾病的潜在药物。
E3092 Paeoniae Radix Rubra Extract Paeoniae Radix Rubra Extract提取自赤芍Paeoniae Radix Rubra,通过抑制GSK3β活性改善炎症,预防深静脉血栓形成。
E3093 Vignae Semen Extract Vignae Semen Extract是从赤小豆Vignae Semen中提取的,具有利尿缓解水肿,排脓,排毒的作用。
E3094 Flatstem Milkvetch Seed Extract Flatstem Milkvetch Seed Extract是由充蔚子Flatstem Milkvetch的干燥成熟种子提取,有益肝益肾、止精、抑尿、明目之功效。
E3095 Pyrethrum Extract Pyrethrum Extract是从除虫菊Pyrethrum中提取的,可以诱导HCT细胞凋亡,因此可以作为一种治疗结直肠癌的新疗法。
E3096 Broussonetiae Fructus Extract Broussonetiae Fructus Extract提取自楮实子Fructus Broussonetiae,可显著提高阿尔茨海默病大鼠体内免疫球蛋白结合蛋白的表达,降低PKR样内质网激酶和C/EBP同源蛋白的表达水平,显著改善其学习、记忆和空间识别功能障碍。
E3098 Fritillariae Cirrhosae Bulbus Extract Fritillariae Cirrhosae Bulbus Extract提取自川贝母Fritillariae cirrhosae,通过STAT1STAT4介导的共调控网络介导细胞凋亡,这可能是其抗肿瘤活性的关键新机制。
E3099 Fritillaria Cirrhosa Seed Extract Fritillaria Cirrhosa Seed Extract是从川贝母Fritillaria Cirrhosa的种子中提取的,其具有镇咳、祛痰、抗哮喘和抗炎等特性,被广泛用于治疗呼吸道疾病。
E3100 Sichuan Pepper Extract Sichuan Pepper Extract从川椒Zanthoxylum bungeanum Maxim.中提取,具有神经保护作用。
E3101 Toosendan Fructus Extract Toosendan Fructus Extract是从川楝子Fructus Meliae Toosendan中提取的,具有强效抗球虫作用,也可作为控制禽球虫病的替代抗球虫剂。
E3102 Cyathulae Root Extract Cyathula root extract从川牛膝Cyathulae的根中提取。
E3104 Chuanxiong Rhizoma Extract Chuanxiong Rhizoma Extract从川穹Echinacea Purpurea中提取,应用于食品领域,常作为添加剂使用,具有明显的香味,能促进消化,增加食欲。
E3105 Cochinchina Cudrania Root Extract Cochinchina Cudrania Root Extract是从穿破石(柘木Cochinchina Cudrania的根)中提取的,具有抗脂质过氧化活性。
E3106 Dioscoreae Nipponicae Rhizoma Extract Dioscoreae Nipponicae Rhizoma Extract提取自穿山龙Dioscorea nipponica的根茎,其主要成分降低IGF-1R中的磷酸化,进而抑制PI3K-AKT和Rap1-MEK信号通路的磷酸化和激活,促进细胞凋亡和格雷夫斯病(Graves’ disease)缓解。
E3107 Andrographis Herba Extract Andrographis Herba Extract提取自穿心莲Andrographis paniculata (Burm. F.) Nees的地上部分,具有多种活性,包括抗菌和抗氧化,抗疟疾,抗血管生成,抗炎,抗糖尿病,和体外α-葡萄糖苷酶和α-淀粉酶抑制活性。
E3109 Cymbidium Extract Cymbidium Extract是从春兰Cymbidium中提取的,具有镇痛和抗炎活性。
E3110 Graviola Extract Graviola Extract是从刺果番荔枝( Annona muricata) 中提取的,对各种人类肿瘤和疾病因子具有治疗作用。
E3111 Tribulus Terrestris Extract Tribulus Terrestris Extract是从刺蒺藜Tribulus Terrestris中提取的,具有抗炎、镇痛、解痉、抗癌、抗菌、驱虫、杀幼虫和抗龋齿等作用。
E3112 Rosa Roxburghii Fruit Extract Rosa Roxburghii Fruit Extract 从刺梨(Rosa Roxburghii)的果实中提取,具有通过调节血浆代谢物和肠道微生物预防2型糖尿病的潜力。
E3113 Rosa Roxburghii Root Extract Rosa Roxburghii Root Extract是从刺梨根(刺槐Rosa Roxburghii的根)中提取的,用于治疗人畜腹痛、急性细菌性痢疾、肠胃炎等疾病。
E3115 Erythrina Variegata Extract Erythrina Variegata Extract从刺桐Erythrina Variegata中提取,是一种民间药物,用于治疗关节炎疼痛。
E3116 Acanthopanax Senticosus Extract Acanthopanax Senticosus Extract提取自刺五加Acanthopanax Senticosus,对小鼠回肠功能具有通过毒蕈碱乙酰胆碱受体(mAChRs)收缩和直接弛缓的双重作用,其弛缓作用可用于治疗腹泻症状,使副交感神经活性增加。
E3117 Amla Extract Amla Extract是从醋栗(Emblica officinalis)的果实中提取的,对炎症、癌症、骨质疏松症、神经系统疾病、高血压等多种疾病以及生活方式疾病、寄生虫病和其他感染性疾病都有疗效。
E3249 Mimosa Pudica Root Extract Mimosa Pudica Root Extract 从含羞草Mimosa Pudica的根中提取,通过增加尿量表现出显着的利尿活性。
E3250 Mimosa Pudica Extract Mimosa Pudica Extract是从具有降血脂活性的含羞草Mimosa Pudica中提取的。
E3251 Tropaeolum Majus Extract Tropaeolum Majus Extract从旱金莲Tropaeolum majus 中提取,在高渗条件下可对抗细菌感染并减少细胞凋亡和 DNA 损伤。
E3253 Chrysanthemum Morifolium Ramat Extract Chrysanthemum Morifolium Ramat Extract是从杭白菊Chrysanthemum morifolium Ramat中提取的,它在世界范围内很受欢迎,对胰岛素抵抗、炎症和心血管疾病有潜在的作用。
E3254 Terminalia Chebula Extract Terminalia Chebula Extract是从诃子Terminalia Chebula中提取的,具有抗氧化、保护肝脏、保护神经、细胞毒、抗糖尿病和抗炎活性
E3255 Albiziae Flos Extract Albiziae Flos Extract提取自合欢花Flos albiziae,传统医学用于治疗失眠和焦虑。
E3256 Albiziae Cortex Extract Albiziae Cortex Extract是从合欢皮(Albiziae Cortex/i>)中提取的,具有镇静催眠作用和神经保护作用。
E3257 Polygoni Multiflori Root Extract Polygoni Multiflori Root Extract提取自何首乌Polygoni Multiflori的根部,用于治疗已扩散至淋巴结的肺结核、癌症、前列腺炎症(前列腺炎)和便秘。
E3258 Nelumbinis Folium Extract Nelumbinis Folium Extract是从荷叶Nelumbo nucifera中提取的,具有良好的降血脂、抗氧化和抗炎的生物活性。
E3260 Seminis Juglandis Septum Extract Seminis Juglandis Septum Extract从分心木Diaphragma juglandis中提取,这是核桃仁的干木隔膜,是核桃生产的著名副产品之一。
E3261 Juglandis Semen Extract Juglandis Semen Extract是从常用于膝关节骨性关节炎治疗的核桃仁Juglandis Semen中提取的。
E3262 Walnut Leave Extract Walnut Leave Extract是从核桃Juglans的叶子中提取的,具有抗菌和抗寄生虫的特性。
E3263 Black Soya Bean Extract Black Soya Bean Extract是从黑豆(Glycine max(L.)merr.)中提取的,其花青素含量高,具有抗氧化和抗蘑菇酪氨酸酶的活性。
E3264 Black Bone Rattan extract Black Bone Rattan Extract是从黑骨藤Gardneria angustifolia中提取的,具有祛风湿、通经活血的功效。
E3265 Black Pepper Extract Black Pepper Extract是从黑胡椒Piper nigrum中提取的,它具有抗氧化、抗菌和胃保护模块。
E3266 Black Carrot Extract Black Carrot Extract是从黑胡萝卜Daucus carota ssp. sativus var. atrorubens,它是一种神经保护剂。
E3267 Black Coffee Extract Black Coffee Extract是从黑咖啡Coffea中提取的,对认知和情绪有好处。
E3268 Black Quinoa Extract Black Quinoa Extract是从具有抗氧化活性的黑藜麦Chenopodium quinoa中提取的。
E3269 Black Ant Extract Black Ant Extract是从黑蚂蚁Polyrhachis vicina中提取的,用作各种滋补品或保健食品的功能性成分。
E3270 Black Rice Extract Blackberry Extract是从黑米中提取的。
E3271 Black Cohosh Extract Black Cohosh Extract是从黑升麻(cimicifuga racemosa)中提取的。
E3272 Black Garlic Extract Black Garlic Extract是从黑蒜Allium nigrum中提取的,具有抗氧化、抗炎、抗癌、抗肥胖、抗糖尿病、抗过敏、保护心脏和保护肝脏的作用。
E3273 Black Sesame Extract Black Sesame Extract是从芝麻Sesamum radiatum中提取的,这可能是一种有效的改善疾病的膳食补充剂。
E3274 Nigella Sativa Extract (Herb) Nigella Sativa Extract (Herb) 从黑种草Nigella Sativa中提取,已被广泛用作抗高血压、补肝、利尿、消化、止泻、刺激食欲、镇痛、抗菌和用于皮肤病。
E3275 Nigella Sativa Extract (Seed) Nigella Sativa Extract (Seed) 从黑种草Nigella Sativa 的种子中提取,可能具有抗糖尿病、抗癌、免疫调节剂、镇痛、抗菌、抗炎和抗氧化特性。
E3276 Red Ginseng Extract Red Ginseng Extract是从红参中提取的,可以提高人体的抗炎抗癌免疫力。
E3277 Black Tea Extract Black Tea Extract是从红茶Camellia sinensis中提取的,对减轻体重有积极作用。
E3278 Black Tea Root Extract Black Tea Root Extract从山茶Camellia sinensis的根中提取,对牙质有保护和修复作用。
E3279 Kombucha Extract Kombucha Extract是从红茶菌Kombucha中提取的,具有很强的抗氧化和抗菌性能。
E3280 Trifolium Pratense Extract Trifolium Pratense Extract是从红车轴Trifolium Pratense中提取的,具有抗氧化和抗癌作用。
E3281 Eleutherine Plicata Extract Eleutherine Plicata Extract提取自红葱Eleutherine plicata,是一种很有潜力的药用植物,其与caspase-8结合,从而导致细胞毒性。
E3282 Taxus Cuspidata Extract Taxus Cuspidata Extract是从红豆杉Taxus Cuspidata中提取的,具有抗菌、抗氧化、抗癌、抗衰老等功效。
E3283 Red Bean Extract Red Bean Extract是从红豆中提取的,具有多种功能特性,如抗糖尿病、抗衰老、抗炎、抗癌和保护肝脏等。
E3284 Safflower Extract Safflower Extract是从Carthamus tinctorius L.中提取的,对阿尔茨海默病(AD)的治疗具有积极作用。
E3285 Rhodiola Rosea Extract Rhodiola Rosea Extract是从红景天(Rhodiola Rosea)中提取的。
E3286 Rambutan Extract Rambutan Extract从红毛丹Nephelium lappaceum中提取,可改善血压和其他代谢参数。
E3287 Red Yeast Rice Extract 红曲米提取物是从红曲米Monascus purpureus中提取的,是有效的降胆固醇保健品。
E3288 Red Raspberry Extract Red Raspberry Extract提取自红树莓Rubus idaeus,其中含有丰富的生物活性成分,具有降低氧化应激的作用。
E3290 Citrus Grandis Fruit Extract Citrus Grandis Fruit Extract是从红西柚Citrus maxima的果实中提取的,具有营养和生物活性。
E3291 Hydrolyzed Rhodophycea Extract Hydrolyzed Rhodophycea Extract是从红藻Hydrolyzed Rhodophycea中提取的,它是一种潜在的抗癌剂。
E3292 Hericium Erinaceus Extract Hericium Erinaceus Extract是从猴头菇Hericium Erinaceus中提取的,可用于治疗抑郁症。
E3293 Magnolia Bark Extract Magnolia Bark Extract 从厚朴Magnolia的树皮中提取,可用于治疗糖尿病和糖尿病相关疾病。
E3294 Piper Nigrum Seed Extract Piper Nigrum Seed Extract从胡椒Piper nigrum L.中提取,具有抗菌、抗氧化、抗糖尿病、降血脂、抗炎、镇痛、抗惊厥和神经保护作用。
E3297 Fenugreek Seed Extract Fenugreek Seed Extract是从葫芦巴Trigonella foenum-graecum的种子中提取的,具有抗菌和抗癌的作用。
E3298 Viscum Coloratum Extract Viscum Coloratum Extract提取自槲寄生Viscum Coloratum,用于治疗炎症性疾病。
E3019 Semen Ginkgo Extract Semen Ginkgo Extract提取自白果Semen Ginkgo
E3020 Hedyotic Diffusa Extract Hedyotic Diffusa Extract是从白花蛇舌草Hedyotic diffusa中提取的,Hedyotic diffusa多糖具有抑制CNE2细胞生长的作用,其作用机制可能与诱导细胞凋亡有关,而细胞凋亡与Baxcaspase-3蛋白的激活和Bcl-2蛋白表达的下调有关。
E3021 Chaga Mushroom Extract Chaga Mushroom Extract是从白桦茸Inonotus obliquus中提取的,显示出强大的抗肿瘤活性,在一些国家已被用于治疗癌症。
E3022 Bletilla Striata Root Extract Bletilla Striata Root Extract是从兰科植物白芨Bletilla Striata的根部提取物。
E3023 White Mustard Seed Extract White Mustard (Brassica Alba) Seed Extract是白芥Brassica Alba种子的提取物。
E3024 Ampelopsis Japonica Root Extract Ampelopsis Japonica Root Extract从白蔹Ampelopsis japonica中提取,可能是一种新的治疗药物,具有减少或替代corticosteroids的潜力,其机制与调节TNF-α的产生密切相关。
E3025 Salix Alba Bark Extract Salix Alba Bark Extract从Salix Alba的树皮中提取。
E3026 White Radish Extract White Radish Extract从白萝卜Raphanus sativus中提取,具有抗糖尿病作用。
E3027 Imperata Cylindrica Root Extract Imperata Cylindrica Root Extract提取自白茅根Imperata cylindrica Linn. Beauv (禾本科),在印地语中通常被称为Darbh,是“Trinpanchmool”的一种重要药物,广泛用于治疗各种疾病,如尿结石、尿潴留、糖尿病、心脏疾病、痛风、常见的咳嗽和感冒、炎症、贫血,作为壮阳药等。
E3029 White Paeony Root Extract White Paeony Root Extract是从白芍Paeonia lactiflora Pall.中提取的,可通过ROCK/AMPK通路减轻高胆固醇血症大鼠肝损伤。
E3031 Bunge Auriculate Root Extract Bunge Auriculate Root (Baishouwu) Extract是从中药白首乌Cynanchum auriculatum, Cynanchum bungeiCynanchum wilfordii的块茎中提取而成,是中药材中著名的补药,具有补血滋补、增强免疫力的功效。
E3032 Atractyloides Macrocephala Root Extract Atractyloides Macrocephala Root Extract是从白术Atractylodes macrocephala Koidz.中提取的,可通过LKB1-AMPK-TFEB通路调控溶酶体自噬。
E3033 Pulsatillae Extract Pulsatillae Extract是从白头翁Pulsatilla chinensis中提取的,其主要活性成分可通过阻断MAPK信号通路减少肿瘤的发生、转移和免疫抑制。
E3001 Donkey-hide gelatin Extract Donkey-hide gelatin Extract来源于阿胶,阿胶是药食同源,可以增强免疫反应,改善代谢平衡,治疗妇科疾病。
E3002 Asafetida Extract Asafetida Extract从新疆阿魏Ferula sinkiangensis K. M. Shen或福建阿魏Ferula fukanensis K. M. Shen中提取而来,具有杀灭肠道蠕虫、治疗寄生虫引起的营养不良、胃腹肿胀疼痛、腹包块、感冒、疟疾、腹泻、预防麻疹等作用。
E3003 Artemisis Princeps Leaf Extract Artemisis Princeps Leaf Extract是从艾叶Artemisia princeps Panpanini中提取的,含有一部分小分子化合物,在体外刺激血管内皮细胞增殖,对促进损伤内皮细胞的恢复有一定的作用。
E3004 Eucalyptus Leaf Extract Eucalyptus Leaf Extract提取自Eucalyptus spp.的叶子。
E3005 Boesenbergia Pandurata Extract Boesenbergia Pandurata Extract源自凹唇姜Boesenbergia Pandurata,具有抗炎,抗氧化和镇痛活性。
E3006 Fructus Anisi Stellati Extract Fructus Anisi Stellati Extract从八角Illicium verum果实中提取,参与靶向胃癌细胞癌细胞凋亡、增殖和肿瘤转移的信号通路。
E3007 Marlea platanifolia Extract Marlea platanifolia Extract是从八角枫Marlea platanifoli中提取的,具有抗炎和镇痛活性。
E3008 Eight clawed Golden Dragon extract Eight clawed Golden Dragon extract是从八爪金龙(Ardisia crispa(Thunb.)A.DC.)中提取的,具有抗血管生成作用。
E3009 Morinda Root Extract Morinda Root Extract源自巴戟天Morinda officinalis How,具有抗炎和抗氧化作用。
E3011 Sarsaparilla Extract Sarsaparilla Extract源自菝葜Smilax china L.,可以通过β3-AR/AMPK信号通路,将3T3-L1脂肪细胞刺激为棕色样脂肪细胞。
E3012 Semen Lablab Album Extract Semen Lablab Album Extract提取自豆科植物扁豆Dolichos Lablab L.的白色种子。土炒白边豆仁(Baibiandouren, Lablab Semen Album fried with earth, TCBBDR)通过多化合物、多靶点协同作用对糖尿病有治疗作用。
E3013 Chinese Cabbage Extract Chinese Cabbage Extract提取自白菜Brassica rapa var.glabra Regel
E3014 White Tea Extract White Tea Extract是从的白茶Camellia sinensis中提取的,它具有抗炎和抗氧化的特性,对皮肤有保护作用,防止皱纹,晒伤和紫外线损伤。
E3015 Amomum Kravanh Extract Amomum Kravanh Seed Extract是从白豆蔻Amomum Kravanh种子中提取的,具有抗氧化、保护DNA损伤、抗菌活性和清除亚硝酸盐的能力。
E3016 Cissus modecoides var Extract Cissus Modecoides Var Extract源自白粉藤Cissus Modecoides Var
E3017 Poria Cocos Extract Poria Cocos Extract提取自茯苓提取物Poria cocos,可通过PI3K/Akt/mTOR信号通路刺激水通道蛋白-3的表达。
E3000 Ligusticum Sinense Extract Ligusticum Sinense Extract来源于中药藁本Ligusticum sinense
E3603 Ramulus Mori Extract Ramulus Mori Extract 来源于桑枝,即植物桑 Morus alba L.的干枝。桑枝是广泛用于治疗糖尿病的传统药物。桑枝的主要活性成分是桑椹苷A、氧化白藜芦醇、白藜芦醇、4-羟基肉桂酸、7-羟基香豆素和桑色素,这些成分已被证明具有抗癌、抗高血压、抗糖尿病和抗炎特性。
E3604 Adenophora Stricta Extract Adenophora Stricta Extract 来源于沙参Adenophora stricta Miq.,沙参通常用于化痰、清肺和健胃。
E3605 Sea buckthorn Extract (fruits) Sea buckthorn Extract (fruits)来源于沙棘(Hippophae rhamnoidesL.)果实。沙棘具有显著的心脏保护作用和心血管系统治疗作用,包括抑制血小板活化(特别是血小板聚集),降低胆固醇浓度和血压,提供抗氧化活性。沙棘还具有抗菌和抗病毒特性。
E3606 Sea buckthorn Extract (leaves) Sea buckthorn Extract (leaves)源于沙棘(Hippophae rhamnoidesL.)的叶子。沙棘具有显著的心脏保护作用和心血管系统治疗作用,包括抑制血小板活化(特别是血小板聚集),降低胆固醇浓度和血压,提供抗氧化活性。沙棘还具有抗菌和抗病毒特性。
E3607 Crateva nurvala Extract Crateva Nurvala Extract来源于沙梨木Crataeva nurvala Buch. 的树皮。沙梨木是一种重要的药用植物,其茎皮部分主要用于阻塞性和非阻塞性尿路病的研究。沙梨木也用于治疗前列腺肿大和恢复膀胱敏感性。
E3608 Semen astragali complanati Extract Semen astragali complanati Extract来源于沙苑子,即扁茎黄芪Astragalus complanatus Bunge的干燥成熟种子。沙苑子的主要成分包括脂肪酸,氨基酸,多糖,类黄酮,三萜糖苷和微量元素。沙苑子对心血管疾病,糖尿病和癌症等慢性疾病表现出治疗效果。
E3609 Elaeagnus angustifolia Extract Elaeagnus angustifolia Extract来源于沙枣Elaeagnus angustifolia L.的果实。沙枣果实提取物具有急性和慢性抗炎活性。
E3610 Amomum villosum Extract Amomum Villosum Extract来源于姜科草本植物砂仁Amomum villosum Lour.。砂仁已被证实可有效治疗肠胃疾病。砂仁水提取物显著减轻炎症性肠病大鼠的肠道炎症。
E3611 Camellia japonica Extract Camellia Japonica Extract是山茶花 Camellia japonica L.的花朵。山茶花具有抗菌、抗氧化和抗肿瘤活性,并且是多酚类物质(如儿茶素)的重要来源。
E3612 Cremastra appendiculata Extract Cremastra Appendiculata Extract来源于山慈菇 Cremastra appendiculata (Pseudobulbus Cremastrae seu Pleiones)。山慈姑是兰科植物的干燥假鳞茎。山慈菇具有抗菌、抗高血压、治疗痛风、抗肿瘤和乙酰胆碱受体M3阻断作用。山慈菇提取物可用于治疗肺癌、肝癌和乳腺癌。
E3613 Sophora tonkinensis Extract Sophora Tonkinensis Extract 来源于豆科植物越南槐Sophora tonkinensis Gapnep.的干燥根茎。山豆根用于治疗咽喉疾病。山豆根具有保肝、免疫调节和抗癌作用,对肝脏、神经和心血管系统有明显毒性。
E3614 Arnica montana Extract Arnica Montana Extract是从菊科植物山金车Arnica montana L.的花中提取的。山金车具有抗炎、免疫调节、抗硬化、镇痛、抗真菌、抗氧化、抗菌和抗癌的生物活性。
E3616 Kaempferia galanga Extract Kaempferia Galanga Extract提取于姜科植物山奈Kaempferia galanga L.。山奈用于缓解消化不良、肿胀、疼痛、高血压和血脂异常。
E3617 Galega officinalis Extract Galega Officinalis Extract是从山羊豆Galega officinalis L.种子中提取的。山羊豆提取物具有降血糖和抗氧化作用。
E3618 Yam Extract Yam Extract 来源于中国山药,即各种薯蓣科山药属植物 Dioscorea opposita Thunb.的根茎。山药主要含有蛋白质、糖、维生素、脂肪、胆碱、淀粉酶、碘、铁、钙、磷等人体不可缺少的微量元素。山药的主要药理作用包括抗氧化、抗衰老、抗肿瘤、降血糖等。山药还能增强免疫力。
E3619 Lonicerae Flos Extract Lonicerae Flos Extract 是从忍冬科植物山银花Lonicera japonica的花蕾中提取的。山银花是一种传统中药,用于治疗炎症和传染病。金银花提取物提高盲肠结扎和穿刺诱导的脓毒症大鼠的存活率。
E3620 Corni Fructus Extract Corni Fructus Extract是从山茱萸Cornus officinalis Sieb. et Zucc.果实中提取的。山茱萸是一种中药,具有抗炎、糖尿病肾病、肿瘤、抗氧化和抗衰老的药理作用。
E3621 Crataegi fructus Extract Crataegi Fructus Extract是从山楂果实中提取的。山楂是植物山里红Crataegus pinnatifida Bge.var. major N. E. Br.或山楂Crataegus pinnatifida Bge.的成熟果实。山楂提取物和其中的化合物具有多种药理活性,例如对心力衰竭患者的保护作用,以及增强心肌收缩力、改善冠状动脉循环、抗氧化作用和抗菌活性。
E3623 Pelargonium hortorum Extract Pelargonium Hortorum Extract是从天竺葵Pelargonium hortorum L.H. Bailey中提取的。天竺葵属被报道是金属超积累植物。天竺葵属植物能酸化土壤pH值。天竺葵有在芽中积累铅的能力。
E3624 Phytolaccae Radix Extract Phytolaccae Radix Extract是从商陆(Phytolacca acinosa Roxb.或 Phytolacca americana L.)的干燥根中提取的。商陆被广泛用于治疗炎症相关疾病。
E3625 Cnidii Fructus Extract Cnidii Fructus Extract 是从蛇床子Cnidium monnieri (L.)Cuss.的干燥成熟果实中提取的。中药蛇床子对慢性腰痛和阳痿有显著疗效,也常被用于治疗骨质疏松症。
E3626 Snake Gallbladder Extract Snake Gallbladder Extract 是从蛇胆中提取的。蛇胆具有多种药理作用,如缓解咳嗽和哮喘,以及提高人体免疫力和视力。在亚洲各国,蛇胆被认为可以提高视力和缓解风湿病。
E3627 Belamcandae Rhizoma Extract Belamcandae Rhizoma Extract 提取于植物射干Belamcanda chinensis (L.) DC.的干燥根茎。射干主要用于治疗咽喉痛、支气管炎和慢性气管炎。从射干根茎中提取的异黄酮,包括野鸢尾苷元,被认为不仅具有抗氧化和抗炎作用,而且还具有抗肿瘤活性。
E3629 Lycopodii Herba Extract Lycopodii Herba Extractt提取自伸筋草,即干燥的石松科植物石松Lycopodium japonicum Thunb.的全株。石松具有抗炎、抗氧化、抗肿瘤活性;传统上用于预防和治疗各种疾病,如类风湿性关节炎、挫伤、四肢瘫痪、痛经。
E3630 Massa Medicata Fermentata Extract Fermented Medicated Mass Extract从神曲Fermented Medicated Mass中提取。
E3631 Cimicifugae Rhizoma Extract Cimicifugae Rhizoma Extract是从具有细胞毒活性的升麻Cimicifuga foetida中提取的。
E3632 Rehmanniae Radix Extract Rehmanniae Radix Extract是从生地黄Rehmannia中提取的,中药用于治疗骨骼疾病,是一种有效的抗骨质疏松症。
E3633 Ginger Extract Ginger Extract是从生姜Zingiber officinale Roscoe中提取的,具有抗氧化潜力并调节STAT6和TNF-α途径。
E3634 Ginger Extract(1%) Ginger Extract(1%)是从姜Zingiber officinale Roscoe中提取的,具有抗氧化潜力并调节 STAT6 和 TNF-α 通路。
E3635 Chasteberry Extract Chasteberry Extract是从圣洁莓agnus castus中提取的。
E3636 Ocimum sanctum Extract Ocimum sanctum Extract提取自圣罗勒Ocimum sanctum,可调节炎症和GLP-1 水平。
E3637 Acorus tatarinowii Extract Acorus Tatarinowii Extract是从石菖蒲Acorus Tatarinowii中提取的,可用于治疗阿尔茨海默病。
E3638 Lysinotus pauciflorus Extract Lysinotus Pauciflorus Extract从石吊兰Lysinotus Pauciflorus中提取,通过caspase-3介导的线粒体途径诱导肝细胞癌细胞凋亡。
E3639 Gypsum fibrosum Extract Gypsum fibrosum Extract是从石膏Gypsum fibrosum中提取的。
E3640 Dendrobii caulis Extract Dendrobii Caulis Extract从石斛Dendrobii Caulis中提取,可通过JNK/c-Jun/MMPs途径保护成纤维细胞免受UVA诱导的光老化。
E3641 Salvia Chinensis Benth Extract Salvia Chinensis Benth Extract是从丹参Salvia Chinensis Benth中提取的,通过诱导DNA损伤途径抑制三阴性乳腺癌进展。
E3642 Haliotidis concha Extract Haliotis Concha Extract从石决明Haliotis Concha的壳中提取,影响钙通道、PMCA1 mRNA的表达,并调节离子钙通道和钙-ATP酶。
E3643 Pomegranate Peel Extract Pomegranate Peel Extract是从石榴Punica granatum L.的皮中提取的。
E0840 Yakuchinone A Yakuchinone-A是从姜科植物益智中分离得到的一种天然产物,对前列腺素(prostaglandins,PGs)白三烯(leukotrienes,LTs)的合成有很强的抑制作用。
E2012 Ginkgolide K Ginkgolide K通过AMPK/mTOR/ULK1信号通路诱导保护性自噬,具有神经保护作用。
S0970 Curzerene Curzerene是从仙茅根茎中分离得到的具有抗癌活性的倍半萜类化合物,可抑制谷胱甘肽S-转移酶A1(GSTA1)的mRNA和蛋白表达,也可诱导细胞凋亡。
S6370 Dendrophenol Dendrophenol (Moscatilin) 是一种来自石斛的天然的双苄基化合物,具有潜在的抗诱变活性。
S0938 Sakuranetin Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
E0505 Olive oil Olive oil来自欧洲橄榄油树Olea europae的果实,对人体健康有益,且具有抗氧化活性和抗炎活性。
E0506 Soybean oil 大豆油是一种从大豆种子中提取的大豆植物油。
E0656 7-Methylcoumarin 7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity.
E0748 Opoponax oil Opoponax oil是从Commiphora erythraea (opoponax)中分离提取的,具有很好的杀虫性能。
E1124 Narciclasine Narciclasine (Lycoricidinol)是一种异羧基生物碱,在他莫昔芬耐药的乳腺癌细胞中通过不同的机制靶向STAT3。Narciclasine通过直接与STAT3 SH2结构域结合,抑制STAT3的磷酸化、激活、二聚和核易位,导致STAT3降解。Narciclasine是一种植物生长调节剂。Narciclasine调节Rho/Rho激酶/LIM激酶/cofilin信号通路,显著增加GTPase RhoA活性,并以RhoA依赖的方式诱导肌动蛋白应激纤维的形成。
E0650 γ-Terpinene γ-Terpinene (γ-TPN)是一种单萜类物质,是一种口服活性抗氧化剂化合物,可直接清除自由基。
E0651 Garlic oil Garlic oil通过诱导II期药物代谢酶阻断烟草致癌物4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone(NNK)诱导的肺肿瘤发生。
S4448 Imidacloprid-urea Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid.
E0653 Trans-ferulic acid Trans-ferulic acid是高糖条件下AMPK的强效激活剂。
E0478 Procyanidin C1 Procyanidin C1是葡萄籽提取物中的一种多酚类成分,通过其对衰老细胞的作用,增加了小鼠的健康寿命和寿命。PCC1是一种具有体内活性的天然感官治疗药物,它可能是一种延缓、缓解或预防年龄相关病理的潜在干预手段。
S0936 Aloin B Aloin B (Isobarbaloin)是从芦荟中分离出来的,是Aloin的一种异构体,具有抗乙型肝炎病毒(HBV)的活性。
S0944 Benzoylaconitine Benzoylaconitine (Isaconitine, Pikraconitin)是从中药附子中提取的一种生物碱,在IL-1β诱导的人滑膜细胞中,可通过MAPK、Akt、NF-κB信号抑制IL-6和IL-8的产生。
E0239 (-)-Catechin gallate (-)-Catechin gallate ((-)-CG)是一种在绿茶提取物中发现的儿茶素多酚,具有多种生物活性。
E0240 Procyanidin B1 Procyanidin B1是一种具有抗氧化特性的天然多酚类化合物,可抑制Kv10.1通道(Kv10.1 channel)进而抑制肝癌的发展。
E0241 Asiaticoside B

Asiaticoside B is a triterpene glycoside isolated from Centella asiatica (L.) Urban, with anti-cancer activity.

E0242 Picrocrocin Picrocrocin是产生藏红花苦味的化学物质,从藏红花中分离出来,可以抑制癌细胞的增殖。
E0243 Emodin-8-glucoside Emodin-8-glucoside (Emodin glucoside B, Anthraglycoside B, Emodin glucoside B)是从芦荟中分离出来的蒽醌衍生物,与DNA的小凹槽结合。
E0244 Acevaltrate Acevaltrate是一种来自草本植物缬草的活性成分,对GBM细胞凋亡的诱导具有显著的诱导作用。Acevaltrate抑制大鼠肾脏和脑半球Na+/K+-ATPase活性,IC50分别为22.8 μM和42.3 μM。
E0246 β-Anhydroicaritin β-Anhydroicaritin是从Boswellia carterii Birdware中分离出来的,具有抗骨质疏松、雌激素调节和抗肿瘤特性。
E0247 Militarine Militarine是白芨块茎的主要化学成分,具有显著的神经保护作用。
E0248 Rehmannioside D (Rhmannioside D) Rehmannioside D (Rhmannioside D)是地黄中的一种环烯醚萜苷成分。
E0249 Pseudolaric Acid A Pseudolaric acid A,一种Hsp90抑制剂,在HL-60、A549、SMMC-7721、HeLa和SW480细胞中的IC50分别为0.60μM、2.72μM、1.36μM、2.92μM和6.16μM,Pseudolaric acid A是土荆皮的主要生物活性成分,诱导细胞周期阻滞在G2/M期,通过caspase-8/caspase-3途径促进细胞死亡,具有有效的抗增殖和抗癌活性。
E0212 Cornuside Cornuside 是一种从 Cornus officinalis SIEB. et ZUCC 果实中分离出来的双环烯醚萜苷化合物。Cornuside 通过抑制 RAW 264.7 巨噬细胞中的 NF-κB 活化来抑制脂多糖诱导的炎症介质。Cornuside 减弱大鼠皮质神经元的细胞凋亡。
E0213 Bruceine D Bruceine D,从灌木 Brucea javanica (L.) Merr. (Simaroubaceae) 中分离出来,在各种人类癌症中具有抗肿瘤特性,包括胰腺癌、乳腺癌、肺癌、血液癌、骨骼癌和肝癌。Bruceine D 通过线粒体途径诱导人慢性粒细胞白血病 K562 细胞凋亡。
E0215 Isorhapontigenin Isorhapontigenin (ISOR) ,从 Belamcanda chinensis 中分离出来,是二苯乙烯的衍生物。Isorhapontigenin 具有有效的抗氧化活性。Isorhapontigenin 抑制白介素 1β 诱导的大鼠软骨细胞炎症和软骨基质损伤。
E0216 Hinokiflavone Hinokiflavone,从 Selaginella P. Beauv、Juniperus phoenicea 和 Rhus succedanea 中分离得到,具有优异的药理活性,包括抗炎、抗氧化和抗肿瘤活性。Hinokiflavone 通过 EMT 信号通路诱导细胞凋亡并抑制乳腺癌细胞的迁移。
E0190 Invert sugar Invert Sugar是一种流行的甜味剂。
E0211 Dihydroberberine Dihydroberberine是小檗碱 (BBR) 的氢化衍生物,通过双重调节 NF-κB 和 MAPK 信号通路发挥抗炎作用。
S0941 3,29-O-dibenzoyloxykarounidiol 3,29-O-dibenzoyloxykarounidiol 是一种从 Trichosanthes kirilowii Maxim 中分离出来的三萜类化合物。
S5813 Isoginkgetin Isoginkgetin是一种天然来源的双黄酮,具有抗肿瘤活性。Isoginkgetin 直接抑制 20S 蛋白酶体 (proteasome) 的糜蛋白酶样、胰蛋白酶样和半胱天冬酶样活性。Isoginkgetin 也是 Pre-mRNA 剪接(splicing) 的通用抑制剂。
S0958 Zingibroside R1 Zingibroside R1 从 Panax zingiberensis Wu et Feng(五加科)的根茎中分离得到,具有一定的抗 HIV-1 活性。Zingibroside R1 显示对 EAT 细胞摄取 2-脱氧-D-葡萄糖 (2-DG) 的抑制作用,IC50 为 91.3 µM,对 MT-4 细胞的生长具有抑制作用,CC50 为 46.2 µM。
E0206 Ginkgetin Ginkgetin 是一种来自银杏叶的双黄酮,具有抗癌、抗炎、抗微生物、抗脂肪生成和神经保护作用。
E0207 Chebulinic acid Chebulinic acid,一种从榄仁树果实中分离的酚类化合物,是一种新型流感病毒神经氨酸酶(Influenza viral neuraminidase)抑制剂。Chebulinic acid 也是一种抗血管生成剂,通过抑制 VEGF 起作用。Chebulinic acid 具有抗肿瘤活性。
E0208 Herbacetin Herbacetin 是一种存在于亚麻籽中的天然类黄酮化合物,具有很强的抗氧化、抗肿瘤和抗炎活性。
E0209 Cinobufotalin Cinobufotalin,可从巨蟾的皮肤分泌物中提取,是一种新型的 SREBP1 抑制剂,通过靶向脂肪生成来抑制肝细胞癌的增殖。
E0210 Quercetin 3-O-β-D-glucuronide Quercetin 3-O-β-D-glucuronide (Miquelianin, Q3GA)是槲皮素代谢物之一,具有抗氧化活性。
E0222 Glaucocalyxin A Glaucocalyxin A 是一种从 Rabdosia japonica var 中分离出来的具有生物活性的 ent-kauranoid 二萜。Glaucocalyxin A具有抗肿瘤和抗炎活性。Glaucocalyxin A 通过人膀胱癌细胞中的 PI3K/Akt 通路诱导 G2/M 细胞周期停滞和凋亡。
E0225 Licochalcone B Licochalcone B (Lico B),从 Glycyrrhiza uralensis Fisch 中提取出来,可诱导人肝癌细胞 HepG2 的细胞周期停滞和凋亡。Licochalcone B 通过破坏 NEK7-NLRP3 相互作用特异性抑制 NLRP3 炎性体
E0226 Chebulagic acid Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的,是一种可逆的、非竞争性的麦芽糖酶(maltase)抑制剂,Ki 值为 6.6 μM。Chebulagic acid 在 LPS 刺激的 RAW 264.7 细胞中显示出有效的抗炎作用。Chebulagic acid 还显示出有效的 COX-LOX双重抑制活性,对 COX-1、COX-2 和 5-LOX 的 IC50 值分别为 15 μM、0.92 μM 和 2.1 μM。
E0233 14-Deoxy-11,12-didehydroandrographolide 14-Deoxy-11,12-didehydroandrographolide (deAND),一种在穿心莲 (Burm. f.) Nees 中的二萜类化合物,具有降血压、抗炎、抗哮喘和抗癌活性。
E0177 Hydrocortisone sodium succinate Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) 对 IL-6 的生物活性有显着的抑制作用,IC50 为 6.7 μM。Hydrocortisone sodium succinate 可与糖皮质激素受体(glucocorticoid receptor) 结合,启动抗炎和免疫抑制介质的转录。
E0201 Hypaconitine Hypaconitine (Deoxymesaconitine) 是一种从乌头属植物中提取的活性二萜生物碱。次乌头碱抑制 TGF-β1 诱导的上皮间质转化。
E0202 Benzoylmesaconine Benzoylmesaconine (Mesaconine 14-benzoate) 是一种主要的乌头生物碱,从几种乌头属植物中分离出来,具有很强的药理活性,如镇痛和抗炎。
E0204 Poricoic acid A Poricoic acid A 是从茯苓的表层中分离出来的 Poricic acid A 激活 AMPK 以减弱肾纤维化中的成纤维细胞活化和异常细胞外基质重塑。Poricic acid A 也是色氨酸羟化酶-1 (tryptophan hydroxylase-1, TPH-1) 的调节剂。
E0205 Strictosamide Strictosamide 是 Nauclea of​ficinalis Pierre ex Pitard(茜草科)的主要代表性成分,具有抗炎和镇痛活性。
S7758 Trabectedin Trabectedin (Ecteinascidin 743, ET-743) 是一种从加勒比被囊动物 Ecteinascidia turbinata 中分离出来的具有抗肿瘤活性的海洋生物碱。Trabectedin 与小沟中鸟嘌呤的 N2 结合,导致 DNA 损伤并以启动子和基因特异性方式影响转录调控。
S0651 N-Butanoyl-L-homoserine lactone N-Butyryl-L-homoserine lactone (N-Butanoyl-L-homoserine lactone, N-Butyrylhomoserine lactone, C4-HSL) 是一种可切割的ADC接头,用于合成抗体药物偶联物(ADC)。N-Butyryl-L-homoserine lactone是一种小的可扩散信号分子,参与群体感应、控制基因表达和细胞代谢。
E0160 Hexaminolevulinate hydrochloride Hexaminolevulinate hydrochloride (5-Aminolevulinic acid hexyl ester hydrochloride)是一种肿瘤光敏剂。
E0365 Fucoidan Fucoidan是从海洋褐藻中提取的阴离子硫酸化多糖,具有广泛的生物活性,包括抗炎、抗癌、抗病毒、抗氧化、抗凝、抗血栓、抗血管生成和抗幽门螺杆菌等。
S0920 Ginkgolide J Ginkgolide J 是银杏叶提取物萜烯三内酯混合物的次要成分,可抑制 GlyR 控制的通道,IC50 为 2.0 μM。Ginkgolide J 还抑制由 Aβ1-42 引起的啮齿动物海马神经元的细胞死亡。银杏内酯 J 具有抗炎活性。
E0198 Pristane Pristane (2,6,10,14-Tetramethylpentadecane, TMPD) 是一种天然的饱和萜类烷烃,主要从鲨鱼肝油中提取,广泛用于诱导小鼠的肿瘤发生和大鼠的关节炎和狼疮性肾炎。
E1029 Miglustat Miglustat (Zavesca, N‐butyldeoxynojirimycin, OGT 918) 是一种口服神经酰胺葡糖基转移酶(ceramide glucosyltransferase)抑制剂,可防止葡糖脑苷脂的溶酶体积聚。
E0196 Alloxan Monohydrate Alloxan Monohydrate是最常用的致糖尿病药物,用于评估测试化合物的抗糖尿病或降血糖能力。
S9793 4-HNE (4-Hydroxynonenal) 4-HNE (4-Hydroxynonenal)是脂质过氧化的主要终产物之一,已被广泛接受为氧化应激的诱导剂。
E0150 Carrageenan Carrageenan (kappa-Carrageenan) 是一种从食用红海藻中提取的天然碳水化合物(多糖)。Carrageenan具有抗凝活性、抗血栓形成活性、抗病毒活性、抗肿瘤活性和免疫调节活性。
E0149 Papain Papain (papaya proteinase I) 是一种来自木瓜果实乳胶的巯基蛋白酶。Papain可分解软骨的细胞间基质。
E0156 Thioacetamide Thioacetamide (TAA) 是一种常用于实验目的的肝毒素,单次给药后会导致小叶中心坏死。
E0154 Taurocholic acid sodium salt Taurocholic acid sodium salt (Sodium Taurocholate, TANa)是牛磺胆酸的钠盐形式,存在于哺乳动物的胆汁中。Taurocholic acid用作利胆剂和利胆剂。
E0143 ITE ITE (2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester)是一种有效的芳烃受体 (AhR) 内源性激动剂,可直接与 AHR 结合,Ki 为 3 nM。
S6812 Z-Guggulsterone Z-Guggulsterone 是阿育吠陀药用植物 Commiphora mukul 的一种成分,在体外和体内抑制血管生成。Z-Guggulsterone 在小胶质细胞中具有抗炎作用。Z-Guggulsterone 通过内在的线粒体依赖性途径诱导胃癌细胞凋亡。
E0129 Oxysophocarpine Oxysophocarpine (OSC) 是从 Sophora alopecuroides 中提取的生物碱。Oxysophocarpine 通过靶向 Nrf2/ HO-1 轴抑制口腔鳞状细胞癌 (OSCC) 的生长和转移。OSC 通过减弱 MAPK 来保护细胞免受细胞凋亡炎症反应并削弱 miR-155 活性和 NF-κB 通路。
E0130 Apigenin-7-O-glucuronide Apigenin-7-O-glucuronide (Apigenin-7-glucuronide) 是在奶蓟中发现的主要黄酮类化合物。Apigenin 7-o-glucuronide 抑制脂多糖激活的巨噬细胞中的肿瘤坏死因子 α (TNF-α) 和总亚硝酸盐释放。
E0015 Iberiotoxin TFA Iberiotoxin (IbTX) 是从蝎子 Buthus tamulus 中纯化的毒素。Iberiotoxin 是大电导 Ca(2+)-activated K+ channel的有效阻滞剂,Kd 约为 1 nM。
S0947 Cafestol Cafestol是从咖啡豆中提取的天然二萜。Cafestol 诱导细胞凋亡并调节多种炎症介质以减轻炎症。Cafestol 抑制 PI3K/Akt 通路。Cafestol 还可以减少白血病细胞系 HL60 中 ROS 的产生。
E0066 Theaflavin 3,3'-digallate Theaflavin 3,3'-digallate (TF-3, ZP10, TFDG) ,一种红茶多酚,是一种有效的寨卡病毒 (Zika virus,ZIKV) 蛋白酶抑制剂,IC50 为 2.3 μM。
E0023 5,7-Dihydroxychromone 5,7-Dihydroxychromone (DHC) 是一种从植物中提取的天然抗氧化剂,是 Nrf2/ARE 信号的有效激活剂。5,7-Dihydroxychromone也是 PPARγ 和 LXRα 的有效激活剂。5,7-二羟基色酮可能有助于调节血糖水平并显示抗糖尿病特性。
E0046 β-Cyclodextrin β-Cyclodextrin (β-CD, Beta-Cyclodextrin) 是一种淀粉的环状衍生物,由部分水解淀粉(麦芽糖糊精)通过酶促过程制备。β-Cyclodextrin可用作络合剂以增加难溶性药物的水溶性并增加其生物利用度和稳定性。
E0124 Chelerythrine Chelerythrine (Toddaline, Broussonpapyrine) 是一种有效的选择性 PKC 拮抗剂,IC50 为 0.66 μM。 Chelerythrine 还抑制 BclXL-Bak BH3 肽结合,IC50 为 1.5 μM。 Chelerythrine 具有抗肿瘤、抗糖尿病和抗炎活性。
S8152 Cucurbitacin I Cucurbitacin-I (Elatericin B, JSI 124, NSC 521777),一种从葫芦科植物中分离出来的天然细胞渗透性三萜,是一种新型的 JAK2/STAT3 选择性抑制剂。
S7580 Leptomycin B Leptomycin B (LMB, CI 940, Elactocin, Mantuamycin, NSC 364372) 是一种从链霉菌中分离的强效抗真菌抗生素,可作为核输出因子 CRM1 的特异性抑制剂。 Leptomycin B 通过共价抑制 CRM1 快速诱导癌细胞系的细胞毒性作用,IC50 值为 0.1 nM–10 nM。
E0037 Bradykinin Bradykinin是一种有效的血管扩张肽,通过刺激特定的内皮 B2 受体发挥其血管扩张作用,从而导致前列环素、NO 和 EDHF 的释放。
S0950 Hibifolin Hibifolin (Gossypetin-8-O-β-D-glucuronide) 是一种黄酮醇糖苷,是 腺苷脱氨酶 (adenosine deaminase, ADA) 的潜在抑制剂,Ki 为 49.92 μM。 Hibifolin 在培养的皮层神经元中防止 β-淀粉样蛋白诱导的神经毒性。
E0010 Hypocrellin A Hypocrellin A (HA) 是一种从 Shiraia bambusicola 中分离的苝醌,显示出抗病毒、抗菌和抗癌的活性。Hypocrellin A 还是 PKC 的选择性和有效抑制剂。
E0027 5-Hydroxymethylcytosine 5-Hydroxymethylcytosine (5hmC) 是哺乳动物基因组DNA中天然存在的成分,被认为是DNA的第六个碱基。5-Hydroxymethylcytosine是活性 DNA 去甲基化的中间代谢物。5-Hydroxymethylcytosine是已知会影响哺乳动物全局基因表达的表观遗传标记。
E0025 2-Hydroxybenzylamine 2-Hydroxybenzylamine (2-(Aminomethyl)phenol, 2-HOBA, NSC 127870) 是一种天然存在于荞麦中的化合物,是二羰基亲电试剂的选择性清除剂,可保护蛋白质和脂质不被这些亲电试剂修饰。2-HOBA 可减少炎症和斑块凋亡细胞,并促进胞吐作用和稳定斑块的特征。2-HOBA 具有用作营养补充剂的潜力,因为它能够防止氧化的破坏作用。
E0008 Atractylodin Atractylodin (Atractydin) 是 Atractylodes lancea 根茎的主要成分之一,抑制 N-酰基乙醇胺水解酸酰胺酶 (NAAA) 的活性,IC50 为 2.81 µM。Atractylodin 还通过阻断 NPM-ALK 激活和 MAPK 来抑制白介素 6 (IL-6)
E0009 Harmane Harmane (Harman, Aribine, Aribin, Locuturine, Locuturin, Loturine, Passiflorin, 1-Methylnorharman, NSC 54439)是多种食品、植物和饮料中的常见化合物。Harmane 是一种选择性 monoamine oxidase 抑制剂,对人 MAO A 和 MAO B 的 IC50 分别为 0.5 μM 和 5 μM。Harmane还可以抑制噬菌体 T4 诱导的紫外线核酸内切酶(UV endonuclease)的 无嘌呤/无嘧啶核酸内切酶(apurinic/apyrimidinic (AP) endonuclease) 活性。
E0022 Ophiopogonin D Ophiopogonin D (OJV-VI, Deacetylophiopogonin C) 是一种从中草药麦冬中分离得到的甾体糖苷,具有抗肿瘤作用。Ophiopogonin D 可通过调节 ITGB1/FAK/Src/AKT/β-catenin/MMP-9 信号轴抑制TGF-β1介导的MDA-MB-231细胞转移行为。Ophiopogonin D 还通过抑制小鼠肺上皮细胞中的 AMPK/NF-κB 通路来减轻 PM2.5 诱导的炎症。
S9197 Maltohexaose Maltohexaose(Amylohexaose)是一种含有6个葡萄糖单位的多糖,可归类为麦芽糊精。
S0943 Arenobufagin Arenobufagin是蟾蜍毒液中的天然蟾蜍二烯内酯,通过抑制 PI3K/Akt/mTOR 通路诱导人肝癌细胞凋亡和自噬。
S6909 Levomefolic acid Levomefolic acid (5-MTHF, LMSR, Metafolin, Nutrifolin) 是一种天然的活性叶酸形式,在细胞水平上用于 DNA reproduction、半胱氨酸循环和同型半胱氨酸的调节等功能。
S6927 Dihydroresveratrol Dihydroresveratrol 是一种具有显著生物活性的天然产物,一种有效的植物雌激素,是 hormone receptor 的调节剂。
S3166 Calcium 2-oxoglutarate Calcium 2-oxoglutarate (Calcium oxoglurate, Calcium 2-oxopentanedioate, Calcium α-ketoglutarate, Calcium AKG, Calcium 2-ketoglutaric acid, Calcium oxoglutaric acid) 是2-oxoglutarate的钙盐形式。2-oxoglutarate 是自然存在于生物中的,是众所周知的在柠檬酸循环(Krebs cycle)中ATP或GTP产生的中间体。2-oxoglutarate 是 tyrosinase 的可逆抑制剂,其IC50值为15 mM。
S6100 Picrotoxin Picrotoxin (Picrotin, Cocculin, Cocculus, NSC 403139) 是一种植物生物碱,是神经元 GABAglycine receptors 的非竞争性拮抗剂。此产品为危化品(急性毒性/易燃/皮肤腐蚀),请在穿戴防护面罩、防护手套和防护服后使用。
S5910 Alpha-Estradiol Alpha-Estradiol (α-Estradiol, 17 alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2) 是一种天然的、非雌性化,是生理上几乎无活性的激素17β-雌二醇(17β- E2)的立体异构体,是雌激素 estrogen 的弱抑制剂。
S5417 Spectinomycin dihydrochloride pentahydrate Spectinomycin dihydrochloride pentahydrate (Trobicin) 是一种广泛使用的抗生素,可通过阻止信使RNA的易位和核糖体上的转移RNA来抑制细菌蛋白质的合成。
S5972 Hydrocortisone hemisuccinate Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate) 是一种具有抗炎特性的生理性糖皮质激素,是 proinflammatory cytokine 的抑制剂,对 Interleukin-6 (IL-6)IL-3 的IC50值分别为6.7 μM和21.4 μM。
S9827 Iodoacetamide Iodoacetamide (IA, IAM, 2-Iodoacetamide) 是一种烷基化剂,通常在蛋白质组学样品制备过程中用于半胱氨酸的烷基化。
S5958 Metformin Metformin (1,1-Dimethylbiguanide) 是一种广泛用于治疗2型糖尿病的药物,可激活肝细胞中的 AMP-activated protein kinase (AMPK)。Metformin 可促进单核细胞中的线粒体自噬。Metformin 可通过激活 JNK/p38 MAPK 途径和GADD153来诱导肺癌细胞凋亡。
S5937 DL-Carnitine DL-Carnitine ((±)-Carnitin) 是L-Carnitine和D-Carnitine的外消旋混合物,可调节线粒体中的 fatty acid transport。DL-Carnitine 被发现对肌肉细胞和心肌无效或有毒。DL-Carnitine 可引起肌无力和心律不齐的症状。
S5955 Thiamine nitrate Thiamine (Vitamin B1) nitrate 是一种必需的维生素,它在细胞从摄入食物中产生能量时发挥重要作用,并可增强正常的神经元活性。
S5888 Beclamide Beclamide (N-Benzyl-3-chloropropionamide, beta-chlorpropionamide) 具有镇静和抗惊厥作用。
S5199 Oxytetracycline hydrochloride Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride 是一种抗生素,会干扰细菌产生必需蛋白质的能力。
S4486 Thiamine monochloride Thiamine (Vitamin B1) monochloride 是一种必不可少的维生素 vitamin,它在摄取食物的细胞能量生产中起着重要作用,并能增强正常的神经元活性。
S4495 Quinine Quinine 是一种来自cinchona tree的生物碱,是一种抗疟疾剂和钾通道 potassium channel 的抑制剂,可抑制电压诱发的mSlo3 (KCa 5.1)通道电流,脉冲至+100 mV,其IC50值为169 μM。[2]

S4490 Tetracycline Tetracycline (TC) 是一种广谱的抗生素,对多种微生物具有活性,包括革兰氏阳性和革兰氏阴性细菌、衣原体、支原体、立克次氏体和原生动物寄生虫。
S3590 Triolein Triolein 是一种 metalloproteinase-1 (MMP-1) 的抑制剂,可降低辐射角化细胞中 IL-6ROS 的表达。
S4713 Atropine Atropine (Atropen, Atnaa, Tropine tropate, DL-Hyoscyamine) 是一种具有竞争性的 muscarinic acetylcholine receptor (mAChR) 的拮抗剂,具有抗近视作用。
S5193 L-Thyroxine sodium salt pentahydrate L-Thyroxine (Levothyroxine, L-T4) sodium salt pentahydrate 是一种合成的T4激素,可用于平衡甲状腺功能减退症。
S5260 ATP ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) 是一种多功能的三磷酸核苷,是免疫和炎症反应中重要的内源性信号分子。
S5790 Folinic acid (Leucovorin) Folinic acid (Leucovorin) 是一种生物叶酸,可增加组织中叶酸还原的水平,从而促进对 thymidylate synthase (TS) 的抑制。在溶液中不稳定,请现配现用!
S6466 Eicosapentaenoic acid ethyl ester Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) 是omega-3 fatty acid 药剂,可显著地降低 triglyceride (TG) 的水平并改善其他脂质参数而不会显着增加低密度脂蛋白(LDL)胆固醇的水平。
S4979 Procaine penicillin G Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R) 是一种将青霉素G与Procaine相结合的结晶复合物,一种β-内酰胺抗生素。
S5922 L-Carnitine hydrochloride L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride 可改善氧饱和度,并抑制 leukotriene 的合成。L-Carnitine hydrochloride 的功能是将长链脂肪酰基辅酶A转运到线粒体中,以通过β氧化降解。
S0911 Hypaphorine Hypaphorine 大量存在于王不留行vaccaria semen中,通过抑制 ERK 或/和NFκB信号通路来抵消炎症。
S4857 L-Ornithine L-ornithine ((S)-2,5-Diaminopentanoic acid) 通过增加能量消耗的效率及促进氨的排泄而具有抗疲劳的作用。它是尿素循环中的关键反应物之一。
S3578 Pyrroloquinoline quinone Pyrroloquinoline quinone (PQQ, Methoxatin) 是一种天然的抗氧化剂,具有抗氧化和抗衰老的作用。Pyrroloquinoline quinone 可预防雌激素缺乏引起的骨质疏松症。Pyrroloquinoline quinone可通过改善免疫微环境和调节JAK-STAT信号通路减轻小鼠过敏性气道炎症。此产品溶解度不佳,动物实验可用,细胞实验请谨慎选择!
S4496 Maltose monohydrate Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose) monohydrate 是一种非必需营养素,可提供能量,是糖原和淀粉在肠内消化的中间产物,存在于发芽的谷物以及其他植物和蔬菜中。
P1201 LL37 (Human cathelicidin) LL37 (Human cathelicidin, Ropocamptide) 是与Cathelicidin相关的 antimicrobial 抗菌肽,具有强大的趋化和免疫调节特性。
S9631 Puromycin aminonucleoside Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN) 是抗生素puromycin的氨基核苷部分,是 dipeptidyl-peptidase IIcytosol alanyl aminopeptidase 的可逆抑制剂,会在系膜细胞(MCs)中诱导凋亡,并伴有细胞活力下降和炎症反应增强。
S7428 Rocaglamide Rocaglamide (Roc-A) 是从Aglaia物种中分离出来的一种有效的 heat shock factor 1 (HSF1) 活化的抑制剂,对HSF1的IC50值约为50 nM。Rocaglamide 可抑制翻译起始因子 eIF4A 的功能。Rocaglamide 还抑制 NF-κB 的活性。Rocaglamide 具有抗肿瘤活性。
S3569 Spermidine Spermidine 是一种天然的多胺,可刺激细胞保护性 macroautophagy/autophagy
S4438 Benzophenone Benzophenone (Diphenyl ketone, Benzoylbenzene) 可滤除UVA和UVB射线,广泛用于各种防晒霜和个人护理产品中。
S4440 2-Phenylacetamide 2-Phenylacetamide 是从具有雌激素活性的 Lepidium apetalum Willd (LA) 的种子中分离出的主要化合物,可在子宫和MCF-7细胞中增加 Estrogen receptorα (ERα)ERβGPR30 的表达。
S4425 Rifamycin S Rifamycin S 是一种quinone和抗 Gram-positive bacteria(包括MRSA) 的抗生素,是一种用于治疗肺结核和麻风病的临床药物。Rifamycin S 可产生 reactive oxygen species (ROS),并抑制微粒体脂质过氧化 microsomal lipid peroxidation
S4436 Pleuromutilin Pleuromutilin (Drosophilin B, Mutilin 14-glycolate) 是新型抗生素的先导化合物,它通过结合细菌的50S核糖体亚基来抑制细菌蛋白质的合成。
S4494 Methionine Methionine (MRX-1024, D-Methionine) 是 GABAA receptor 的激活剂,可调节神经元活性。
S3588 Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) 是一种衍生自丙酮的氧化溶剂,已广泛用于工业化学品和化妆品中。Hexylene glycol 具有抗菌 antibacterial 和抗真菌 antifungal 的特性。
S3595 D-Gluconic acid D-Gluconic acid 是一种抗真菌 antifungal 药。
S6446 Sodium citrate dihydrate Sodium citrate dehydrate (Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate) 是一种首选的抗凝血剂。
S3594 Adipic acid Adipic acid (Hexanedioic acid) 是一种重要的二羧酸,可用于制造尼龙和聚氨酯塑料。
S3596 PVP (Polyvinylpyrrolidone) PVP (Polyvinylpyrrolidone)是一种惰性的、水溶性的、无毒的、耐温且pH稳定的、具有生物相容性的、可生物降解的聚合物,有助于封装和满足亲水性和亲脂性药物的需求。Polyvinylpyrrolidone 已被广泛测试并用作有效的伤口愈合促进剂。
S3598 Sucrose Sucrose (D-(+)-Saccharose) 是植物天然产生的一种常见糖,是一种二糖,由两个单糖:葡萄糖和果糖组成的分子。
S4424 Hyaluronidase Hyaluronidase (Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase) 是一种天然酶,可降解透明质酸,而透明质酸是细胞外基质的重要组成部分。它通过糖苷键的裂解来解聚透明质酸,并已用于眼科手术。
S0235 Lavendustin B Lavendustin B 抑制 HIV-1 integrase (IN) 与其同源的细胞辅助因子 lens epithelium-derived growth factor (LEDGF/p75) 的相互作用。Lavendustin B 是 Tyrosine Kinase 的抑制剂,也是 glucose transporter 1 (Glut1) 的竞争性抑制剂。
S9794 Melittin Melittin (MLT, Forapin, Forapine) 是 phospholipase A2 (PLA2) 的活化剂,可刺激低分子量PLA2的活性,但不会增加高分子量酶的活性。
S3168 cis-Resveratrol cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) 是Resveratrol的顺式异构体。Resveratrol 是一种天然的酚类化合物,具有抗氧化、抗炎、保护心脏和抗癌的特性。Resveratrol 是 pregnane X receptor (PXR) 的抑制剂,也是 Nrf2SIRT1 的激活剂,并可能诱导凋亡。Resveratrol 还可抑制多种靶标,包括 5-lipoxygenase (LOX)cyclooxygenase (COX)IKKβDNA polymerases αδ,IC50分别为2.7 μM、<1 μM、1 μM、3.3 μM和5 μM。
S3499 Monocaprylin Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) 对金黄色葡萄球菌和大肠杆菌具有优异的抗菌活性。
S0921 Wilforine Wilforine (WR) 是在wilfordii植株中发现的倍半萜吡啶生物碱,可显著地抑制 P-glycoprotein (P-gp) 的外排活性。
S3351 Sodium phenylpyruvate Sodium phenylpyruvate (Phenylpyruvic acid sodium salt) 可抑制氨基酸形成 amino acid formation 并降低氧气消耗。
S2995 4-Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid (4-HPPA) 是一种丰富的多酚结肠代谢产物,是一种有效的清除剂,可抑制 free radicalscyclooxygenase-2 (COX-2) 的水平,并有助于降低结肠癌发展的风险。
S6918 Oleandrin (PBI-05204) Oleandrin (PBI-05204, Foliandrin, Neriolin, Neriostene, Folinerin, Corrigen, Neriol) 是 Na+/K+-ATPase 的抑制剂,IC50值为0.62 μM。Oleandrin 可诱导凋亡并减少人胶质瘤细胞的体外迁移。
S6990 Phytohemagglutinin (PHA) Phytohemagglutinin (PHA)在毕赤酵母中利用天然信号肽或酿酒酵母α-因子前体序列表达,将蛋白质引导至分泌途径。Phytohemagglutinin 可通过增加凋亡蛋白 Bax 和激活 caspases-3 来诱导人HEp-2癌细胞的凋亡。
S3069 Deoxycholic acid sodium salt Deoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) 会特定地激活刺激棕色脂肪组织(BAT)的 TGR5 receptor (GPCR19) 的产热活动。
S3248 2'-Deoxyadenosine 5'-monophosphate 2'-Deoxyadenosine 5'-monophosphate (5'-dAMP) 是一种内源性代谢产物,仅在酸性条件下被光敏降解。
S3268 2'-Deoxycytidine 5'-monophosphate 2'-Deoxycytidine-5'-monophosphoric acid (dCMP) 是一种内源性代谢产物,可以用作描述由二次电子诱导的DNA链断裂机理的模型,并且主要通过C-O磷酸酯键的解离而分解。
S3318 N-Acetyl-L-arginine dihydrate N-Acetyl-L-arginine (Ac-Arg-OH) dihydrate 是一种内源性代谢产物。
S3319 Levoglucosan Levoglucosan (LG, LEV, Leucoglucosan, Glucosan, 1,6-anhydro-b-D-Glucose) 是一种内源性代谢产物。
S3324 Sodium 2-(1H-indol-3-yl)acetate Sodium 2-(1H-indol-3-yl)acetate (3-Indoleacetic acid sodium, Indole-3-acetic acid sodium, 3-IAA sodium) 是一种内源性代谢产物。
S3326 Phytic acid dipotassium salt Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)) 是一种稻谷提取物和消化物中的内源性代谢物,可抑制 β-secretase 1 (BACE1),其IC50值约为0.25 μM。
S3331 2-Aminoethylphosphonic acid 2-Aminoethylphosphonic acid (2-AEP, (2-Aminoethyl)phosphonic acid) 是一种丰富而普遍存在的天然膦酸酯,被许多原核谱系用作磷源。
S3335 Phospho(enol)pyruvic acid monopotassium salt Phospho(enol)pyruvic acid monopotassium salt (Potassium 1-carboxyvinyl hydrogenphosphate) 是一种内源性代谢产物。
S3343 Methyl β-D-Galactopyranoside Methyl β-D-Galactopyranoside (Methyl beta-D-galactoside, Methylgalactoside) 是一种内源性代谢物。
S3370 3-Methoxytyramine hydrochloride 3-Methoxytyramine (3-O-methyl Dopamine, 3MT) hydrochloride 是多巴胺的主要细胞外代谢产物,是一种神经调节剂,在某些情况下可能参与运动控制。
S3310 D-(+)-Galacturonic acid monohydrate D-(+)-Galacturonic acid monohydrate (D-Galacturonic acid hydrate, d-GalA, D-galUA) 是一种内源性代谢产物,可用于工程酿酒酵母中。
S3323 2-Hydroxycaproic acid 2-Hydroxyhexanoic acid (2-Hydroxyhexanoic acid) 是一种内源性代谢产物。
S2997 DL-Tartaric acid DL-Tartaric Acid (2,3-Dihydroxysuccinic acid) 是一种白色结晶有机酸,可从许多植物中,特别是罗望子树tamarinds和葡萄grapes中分离出来,并用作抗氧化剂和添加剂,以赋予酸味。
S3087 N-Acetyl-DL-methionine N-Acetyl-DL-methionine 是一种活性内源性代谢产物,可降低雄性Bom:NMRI mice的肝脏 glutathione 水平。
S3092 Glyoxylic acid monohydrate Glyoxylic acid monohydrate (2,2-Dihydroxyacetic acid) 是一种与大气有关的酮酸。
S3093 Pyrazole Pyrazole (1H-pyrazole) 是具有两个氮原子的五元杂芳族环,具有重要意义。Pyrazole 是设计和开发新药理学必不可少的支柱。
S3094 N-Acetyl-L-alanine N-Acetyl-L-alanine (NAAL, Ac-Ala-OH) 是一种活性内源性代谢产物。
S3157 3-Hydroxybenzaldehyde 3-Hydroxybenzaldehyde (3-HBA) 是自然界中常见的一种苯甲醛,由 3-hydroxybenzyl-alcohol 脱氢酶产生,并且是大鼠和人体中醛脱氢酶(ALDH)的底物。3-Hydroxybenzaldehyde 具有血管保护作用。
S3315 6-Hydroxyindole 6-Hydroxyindole (1H-indol-6-ol) 是一种内源性的有效且持久的 OATP1B1 的抑制剂,其IC50值约为10 μM。
S3334 Glycolaldehyde dimer Glycolaldehyde dimer (2,5-Dihydroxy-1,4-dioxane, 1,4-Dioxane-2,5-diol, DD) 是一种活性内源性代谢产物,当与甘氨酸(Gly)或硫酸铵(AS)反应时,具有中等吸收性和荧光性。
S3336 Heptadecanoic acid Heptadecanoic acid (C17:0) 是一种奇数链饱和脂肪酸,可显著地抑制细胞增殖和迁移,同时促进PC-9和PC‑9/GR细胞的凋亡。Heptadecanoic acid 与多种疾病相关,包括冠心病,前驱糖尿病和2型糖尿病以及多发性硬化症的发生率。
S3337 L-Histidinol dihydrochloride L-Histidinol dihydrochloride 是必需氨基酸L-组氨酸的结构类似物,是一种 protein biosynthesis 的可逆抑制剂,它引起培养中非致瘤和致瘤细胞的不同反应。
S3338 D-(-)-Lyxose D-(-)-Lyxose (D-Lyxose) 是一种活性内源性代谢产物。
S3345 Nα-Acetyl-L-lysine Nα-Acetyl-L-lysine (Ac-Lys-OH, N(alpha)-Acetyllysine) 是一种活性内源性代谢物。
S3347 3-Methylglutaric acid 3-Methylglutaric acid (MGA, 3MG acid) 是一种明显的C6二羧酸有机酸,可以用作单一的固态NMR标准化合物来执行除磁体匀场之外的所有校准步骤。
S3348 O-Acetyl-L-serine hydrochloride O-Acetyl-L-serine (OAS, O-Acetylserine, O-Acetyl-L-serine) hydrochloride (HCl) 是一种细菌和植物中氨基酸半胱氨酸生物合成的中间体,其显示出一种信号功能,不论植物的硫状态如何,它都能改变特定基因的转录水平。
S3358 4-Acetamidobutyric acid 4-Acetamidobutanoic acid (N-acetyl GABA) 是一种 Gamma-aminobutyric acid (GABA) 的衍生物,由GABA氮原子的单乙酰化产生。
S3360 Bis(2-ethylhexyl) phthalate Bis(2-ethylhexyl) phthalate (Dioctyl phthalate, DOP, Diplast O, ESBO-D 82, Ergoplast FDO, Ergoplast FDO-S, Etalon) 可诱导幼虫斑马鱼 Danio rerio 中的 DNA strand breaks 和基因表达改变。
S3095 Itaconic acid Itaconic acid 是一种巨噬细胞特异性 (Mϕ-specific) 代谢产物,可介导巨噬细胞代谢与腹膜肿瘤之间的交互作用。Itaconic acid 还是聚合物,化学品和燃料的前体,可以由许多真菌合成。
S3096 L-Histidine monohydrochloride monohydrate L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O) 是必需氨基酸L-组氨酸的结构类似物,是 protein biosynthesis 的可逆抑制剂,可引起培养中非致瘤细胞和致瘤细胞的不同反应。
S3098 N-Acetylglycine N-Acetylglycine (NAGly, Aceturic acid, Acetamidoacetic acid) 是许多食品的次要成分,没有遗传毒性或急性毒性。
S3097 5,6-Dimethylbenzimidazole 5,6-Dimethylbenzimidazole (5,6-DMB, Dimezol, Dimedazol, 5,6-Dimethyl-1H-benzo[d]imidazole, 5,6-Dimethyl-1H-benzimidazole) 是一种维生素B12的前体。
S3107 D-Pyroglutamic acid D-Pyroglutamic acid (D-5-Oxoproline, D-Pyr-OH, 5-oxo-D-proline, (R)-5-Oxopyrrolidine-2-carboxylic acid) 是一种有效的内源性代谢产物,可对抗由N-methyl-D-aspartate receptor拮抗剂 AP-5 诱导的被动回避行为的中断。
S3109 N-Acetyl-L-leucine N-acetyl-L-leucine 是一种有效的内源性代谢产物,通过在小脑和丘脑中起作用,加速单侧迷路切除后前庭代偿。
S3111 Pyridoxal hydrochloride Pyridoxal hydrochloride (HQ) 是一种活性内源性代谢产物。
S3365 (S)-(-)-1-Phenylethanol (S)-(-)-1-Phenylethanol ((S)-1-Phenylethanol, (S)-(-)-Phenylethanol) 是一种具有风味特性的1-Phenylethanol的对映异构体。
S3366 Monoethyl malonic acid Monoethyl malonic acid (Ethyl hydrogen malonate, Monoethyl malonate, 3-Ethoxy-3-oxopropanoic acid) 是 ethyl 3-ethoxypropionate (EEP) 的主要尿代谢产物。
S3320 (R)-3-Hydroxybutanoic acid (R)-3-Hydroxybutanoic acid (R-3HB, D-3-hydroxybutyric acid) 是PHB (poly[(R)-3-hydroxybutyrate])的单体,具有广泛的工业和医学应用。(R)-3-Hydroxybutanoic acid 也可以用作合成纯的可生物降解的PHB及其共聚酯的手性前体。
S3049 Calcium 2-hydroxy-4-(methylthio)butanoate Calcium 2-hydroxy-4-(methylthio)butanoate 是一种活性内源性代谢物。
S3135 2-Amino-1-phenylethanol 2-Amino-1-phenylethanol (2-APE) 是一种去甲肾上腺素类似物。
S3221 Thymidine 5'-monophosphate disodium salt Thymidine-5'-monophosphate (5'-Thymidylic acid) disodium salt 是一种活性内源性代谢物。
S3311 Myosmine Myosmine 是次要的烟草生物碱之一,并存在于各种食品中。Myosmine 对 a4b2 nicotinic acetylcholinergic receptors (nAChR) 具有低亲和力,Ki为3300 nM。
S3321 N-Methylnicotinamide N-Methylnicotinamide (MNA, Nicotinyl Methylamide, N-Methyl-3-pyridinecarboxamide) 是一种活性内源性代谢产物,可通过调节ADMA-DDAH轴改善内皮功能障碍并减轻动脉粥样硬化。
S3325 L-Cysteic acid monohydrate L-Cysteic acid monohydrate (CAM) 是一种活性内源性代谢物。
S3329 (L)-Dehydroascorbic acid (L)-Dehydroascorbic acid (DHA) 是一种l-Ascorbic acid (AsA)的氧化形式,其在硫醇的存在下可有效地清除非热等离子体诱导的羟基自由基,而自身不能清除羟基自由基。
S3342 Petroselinic acid Petroselinic acid (PSA) 是一种从香菜果实的植物油中分离出来的油酸的位置异构体。Petroselinic acid 可用于新槐糖脂的发酵。
S3344 Serotonin creatinine sulfate monohydrate Serotonin (5-Hydroxytryptamine) creatinine sulfate monohydrate 是一种活性内源性代谢产物。
S3346 1-Methylnicotinamide chloride 1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride 是烟酰胺的活性内源性代谢产物,具有抗炎和抗血栓形成的作用。1-Methylnicotinamide 可增强肿瘤血管的形成,并显著地增加 prostacyclin (PGI2) 的生成。
S3349 Phosphocholine chloride calcium salt tetrahydrate Phosphocholine (Phosphorylcholine) chloride calcium salt tetrahydrate 是一种活性内源性代谢物。
S3350 Cholesteryl linoleate Cholesteryl linoleate 是一种人鼻液中极性较低的脂质,助力固有的抗菌活性。
S3352 Tricosanoic acid Tricosanoic acid 是一种脂族羧酸,具有很强的生发作用。
S3353 Lithium acetoacetate Lithium acetoacetate (LiAcAc, Acetoacetic acid lithium salt, Lithium 3-oxobutanoate) 是一种活性内源性代谢产物,可影响细胞系的生长。Lithium acetoacetate 可用作乙酰乙酸盐标准品,用于测量生物样品中的乙酰乙酸。
S3354 DL-2,3-Diaminopropionic acid monohydrochloride DL-2,3-Diaminopropionic acid monohydrochloride (2,3-Diaminopropanoic acid hydrochloride) 是一种活性内源性代谢物。
S3356 Phosphonoacetic acid Phosphonoacetic acid (PAA) 是一种活性内源性代谢产物,具有限制 DNA biosynthesis 的潜力。Phosphonoacetic acid 具有抗病毒的活性。
S3357 Elaidic acid Elaidic acid 是一种主要的反式脂肪酸,可抑制细胞活力,并通过增强氧化应激 oxidative stress 来促进细胞的凋亡。Elaidic acid 可用作药物溶剂。
S3359 Isomaltulose hydrate Isomaltulose (Palatinose) hydrate 是一种 disaccharide carbohydrate,广泛应用于在运动期间维持血糖和水合作用。
S3361 (3-Carboxypropyl)trimethylammonium chloride (3-Carboxypropyl)trimethylammonium chloride (γ-Butyrobetaine, γBB hydrochloride) 是小鼠饮食中L-carnitine被肠道微生物分解的中间代谢产物。
S3362 D-Gulonic acid γ-lactone D-Gulonic acid γ-lactone (Gulonolactone, D-Gulono-1,4-lactone, 1,4-D-Gulonolactone) 是一种活性内源性代谢物。
S3367 cis-4-Hydroxy-D-proline cis-4-Hydroxy-D-proline (H-D-cis-Hyp-OH) 是一种内源性代谢产物,可用于研究D-丙氨酸脱氢酶的特异性和动力学。
S3368 Uridine-5'-diphosphate disodium salt Uridine-5'-diphosphate (UDP) disodium salt 是一种有效的、选择性的 P2Y6 receptor 的天然激动剂,其EC50值为300 nM,pEC50值为 6.52。Uridine-5'-diphosphate (UDP) disodium salt 也是 P2Y14 receptor 的拮抗剂,pEC50值为 7.28。
S3371 N-Acetyl-D-mannosamine N-Acetyl-D-mannosamine (ManNAc, N-acetyl-beta-mannosamine) 是唾液酸的前体,可改善年龄相关的突触传递和长期增强(LTP)的衰减。N-Acetyl-D-mannosamine 的治疗是认知功能障碍的潜在治疗应用。
S3088 (±)-Methyl Jasmonate (±)-Methyl Jasmonate (MeJA, Methyl jasmonate, Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate),是一种植物激素,在植物中起着至关重要的细胞调节剂的作用,是调节炎症性肠病(IBDs)的新候选药物,可调节 caspase 型蛋白酶家族主要类型的表达。
S3169 2'-Deoxyuridine 5'-monophosphate disodium salt 2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP) 是胸苷酸合酶的底物,并可被转化为deoxythymidine monophosphate (dTMP)。在甲基化步骤中,dUMP对dTMP的抑制作用是控制细菌和真核细胞生长的关键。
S3322 Nicotinuric acid Nicotinuric acid (NUA) 是烟酸的主要排毒产物,可以作为烟酸在肝脏生物转化中的简单定量指标。
S3332 D-Mannosamine hydrochloride D-Mannosamine hydrochloride ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride) 是一种活性的内源性代谢产物。
S3040 Isocitric acid trisodium salt Isocitric acid (DL-Isocitric acid) trisodium salt 是一种活性的内源性代谢产物。
S3089 12-Hydroxydodecanoic acid 12-Hydroxydodecanoic acid (G12) 是一种活性内源性代谢产物。
S3341 Palmitoleic acid Palmitoleic acid (POA, Palmitoleate) 可通过依赖于PPARα的 AMPKFGF-21 活化来刺激肝脏中葡萄糖的摄取。
S2989 Nα-Acetyl-L-asparagine Nα-Acetyl-L-asparagine (N-Acetylasparagine, (S)-2-acetamido-4-amino-4-oxobutanoic acid) 是一种存在于人脑中的内源性代谢产物。
S2991 Thiamine monophosphate chloride dihydrate Thiamine monophosphate chloride dihydrate (Vitamin B1 Monophosphate Chloride, Sineurina, Phosphothiamine) 是一种内源性代谢物。
S2992 Sodium mesoxalate monohydrate Sodium mesoxalate monohydrate (sodium 2,2-dihydroxymalonate) 是一种内源性代谢产物。
S2993 D-Saccharic acid potassium salt D-Saccharic acid potassium salt (D-Glucaric acid potassium, Potassium bisaccharate) 是一种内源性代谢产物。
S2999 Acetic acid octyl ester Acetic acid octyl ester (Octyl acetate) 是野生 parsnip (Pastinaca sativa) 的外壳或油管中精油的主要成分之一。Acetic acid octyl ester 具有抗氧化活性。
S3006 Methyl isoeugenol Methyl isoeugenol (Methylisoeugenol) 是从 Acori Tatarinowii Rhizoma 分离得到的丁香酚类似物异丁香酚。Methyl isoeugenol 是一种对Z. diversus极具吸引力的诱剂,可作为监控和雄性灭计划中的引诱剂。
S3009 Menthone Menthone 是薄荷精油(Mentha piperita L.)的主要挥发性成分之一。Menthone 可用作抗氧化剂,具有良好的补偿作用,可显着减少精子细胞中的 DNA damages
S3091 Methyl acetoacetate Methyl acetylacetate (MAA, Acetoacetate methyl ester, Methyl 3-oxobutanoate, Methyl 3-oxobutyrate, Methyl acetoacetate, Methyl acetylacetate) 是一种内源性代谢产物,可用作合成药物的化学试剂。
S2998 Isophorone Isophorone (IPHO) 是一种α,β-不饱和环状酮,是一种透明的液体,带有樟脑样的气味。Isophorone 可用作聚合物的前体。
S3313 Nudifloric Acid Nudifloric acid (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid),是从一种抗氧化、抗癌、抗炎、抗糖尿病、抗肥胖、抗血管生成和抗伤害感受活动飞虫草 Cordyceps bassiana 中分离出来的。
S3317 cis-3-Hexenyl hexanoate Cis-3-Hexenyl hexanoate ((Z)-3-hexenyl hexanoate) 是一种植物挥发物,可将热带和果肉风味与柑橘和绿色细腻感带入各种水果风味。
S3327 Disodium 5'-inosinate monohydrate Disodium 5'-inosinate monohydrate (Inosine 5'-monophosphate disodium salt hydrate) 是一种内源性代谢物。
S3333 (2R,3R)-(-)-2,3-Butanediol (2R,3R)-(-)-2,3-Butanediol ((2R,3R)-Butane-2,3-diol) 是内源性代谢产物。
S2990 Dihydroxyfumaric acid hydrate Dihydroxyfumaric acid hydrate (DHF) 是一种内源性代谢物。Dihydroxyfumaric acid hydrate (DHF) 的二酯衍生物已专门用作有机合成中的亲电子试剂。
S2988 DL-5-Hydroxylysine hydrochloride DL-5-Hydroxylysine hydrochloride 是一种内源性代谢产物,是5-羟基赖氨酸D-和L-对映体的外消旋混合物,可用作自由基诱导的蛋白质氧化的潜在靶标。
S2994 DL-Homocysteine DL-Homocysteine 是一种弱神经毒素,会影响脑中 kynurenic acid (KYNA) 的产生。DL-Homocysteine 可抑制KYNA生物合成酶、kynurenine aminotransferases (KATs) I和II的活性。
S3099 δ-Valerolactone δ-Valerolactone (Tetrahydro-2H-pyran-2-one, 5-Valerolactone, oxan-2-one) 是一种内源性代谢物。
S3328 N-Formyl-L-methionine N-Formyl-L-methionine (For-Met-OH) 是一种内源性代谢产物。
S6955 Insulin (human) Insulin (human) (Insulin regular) 是一种调节葡萄糖水平的多肽激素。Insulin 通常用于治疗糖尿病患者的高血糖症。效价(potency):29 units/mg。
S2986 9-Methoxycanthin-6-one 9-Methoxycanthin-6-one 是存在于完整的植物部分和不同外植体的愈伤组织中的具有抗肿瘤活性的成分。
S3108 2,5-Dimethylpyrazine 2,5-Dimethylpyrazine (NSC 49139) 是一种内源性代谢产物。
S2996 L-DAB HBR L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) 是一种 GABA (Gamma-aminobutyric acid) transaminase 的抑制剂,IC50值大于500 μM。L-DAB HBR 表现出抗肿瘤活性。
S3029 Malonic acid Malonic acid (MOA) 是气溶胶中的主要dicarboxylic acids (DCAs)之一,通过实验和计算得出,它是一种强酸。Malonic acid (MOA) 可充当形成基于SA-A的纯簇的中介桥。
S3086 Maleic acid Maleic acid 可抑制 glutamate decarboxylase (GAD) 的活性,从而增强 Listeria monocytogenes 的酸敏感性。Maleic acid 会影响细胞外 GABA 的水平。
S3090 trans-Aconitic acid trans-Aconitic acid (TAA) 是Echinodorus grandiflorus(一种在巴西用于治疗类风湿性关节炎的药用植物)的叶子中的丰富成分。
S3101 2-Deoxy-D-ribose 2-Deoxy-D-ribose (Thyminose, Deoxyribose) 是一种内源性代谢产物。
S3118 L-Homoserine L-Homoserine (L-Hse) 是苏氨酸,蛋氨酸和赖氨酸的重要生物合成中间体。
S3123 3-Methyl-2-buten-1-ol 3-Methyl-2-buten-1-ol (Prenol, Prenyl alcohol, Dimethylallyl alcohol) 是一种内源性代谢产物。
S3143 Pyruvic acid Pyruvic acid (Acetylformic acid) 是一种重要的有机化学中间体,在心肌细胞的病理生理和治疗中发挥作用。Pyruvic acid 可显着提高 lactate dehydrogenase (LDH)creatine kinase (CK) 的水平,并降低 Ca2+Mg2+-ATPase 和 Na+K+-ATPase 的水平。
S3084 Guanosine 5'-triphosphate trisodium salt Guanosine 5'-triphosphate (5'-GTP, Guanosine triphosphate, H4GTP) trisodium salt 是鼠细胞中成肌细胞分化的增强剂。Guanosine 5'-triphosphate trisodium salt 可上调miRNA(特别是miR133a和miR133b)和肌原性调节因子,并诱导人肌原性前体细胞在细胞外环境中释放出被鸟苷基分子(主要是鸟苷)填充的外泌体。
S3125 N-Formylglycine N-Formylglycine (2-formamidoacetic acid, For-Gly-OH, FGly) 是一种内源性代谢产物。
S3126 Sodium 2-hydroxybutanoate Sodium 2-hydroxybutanoate (Sodium 2-hydroxybutyrate, Sodium DL-2-hydroxybutyrate)是由2-氨基丁酸转化而成的一种中间代谢物。
S3127 2,4-Dihydroxypyrimidine-5-carboxylic acid 2,4-Dihydroxypyrimidine-5-carboxylic Acid (Uracil 5-carboxylic acid, Isoorotic acid, 5-Carboxyuracil) 是一种内源性代谢产物。
S3128 N-Acetyl-D-galactosamine N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) 是一种内源性代谢物。
S3131 L-(-)-Glucose L-Glucose (L-(-)-Glucose) 是D-葡萄糖的对映异构体。L-Glucose 可促进食物摄取,而细胞不能将其用作能量来源,因为它不能被己糖激酶磷酸化。
S3134 D-(-)-Tartaric acid D-(-)-Tartaric acid 是酒石酸的非天然异构体,它是具有广泛的工业和科学应用的重要手性化学构件。
S3141 Maleimide Maleimide 显示出荧光猝灭能力,并且可以作为荧光探针用于硫醇分析物的特异性检测。Maleimide 还用于生产抗体偶联药物(ADC),用于癌症研究。
S3142 Potassium sorbate Potassium sorbate (Sorbic acid potassium) 是一种无毒的食品防腐剂,它是从 Sorbus aucuparia 中分离出来的。Potassium sorbate 是大多数霉菌,酵母菌和某些细菌的有效抑制剂。
S3145 Pimelic acid Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) 是源自脂肪酸合成途径的枯草芽孢杆菌中生物素的前体。
S3152 Glutaric acid Glutaric acid (GA) 是一种有吸引力的C5二羧酸,在生物化学工业中具有广泛的应用。
S3159 Citraconic acid Citraconic acid (CA) 是一种存在于野生大豆中的甲基支链脂肪酸。
S3316 5-Hydroxy-1-tetralone 5-hydroxy-1-tetralone 是一种荧光标记 fluorescent labeling 的试剂,用于从少量生物样品中测定糖鞘脂。
S3330 Maleamic acid Maleamic acid ((Z)-4-Amino-4-oxobut-2-enoic acid) 是一种内源性代谢产物。
S3339 3-(2-Hydroxyphenyl)propionic acid 3-(2-Hydroxyphenyl)propanoic acid (Melilotic acid, Melilotate, 2-hydroxybenzenepropanoic acid) 是一种内源性代谢产物。
S2987 4-Methyl-2-oxovaleric acid 4-Methyl-2-oxovaleric acid (Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate) 是由星形胶质细胞释放至神经元,可以通过氨基转移酶重新形成亮氨酸。4-Methyl-2-oxovaleric acid 可降低骨骼肌中蛋白质的降解速率。4-Methyl-2-oxovaleric acid 可通过抑制 alpha-ketoglutarate dehydrogenase (oxoglutarate dehydrogenase complex, OGDC) 的活性来发挥 oxidative phosphorylation (OXPHOS) 的解偶联剂和代谢抑制剂的功效。
S3266 L-Anserine nitrate salt L-Anserine nitrate salt 是一种存在于大多数动物组织中的二肽,具有抗氧化、抗交联和抗糖基化的作用。L-Anserine 可防止内质网应激诱导物诱导的神经毒性。
S1273 Amarogentin Amarogentin (AG) 是一种主要从 SwertiaGentiana 根中提取的裂环烯醚苷,具有抗氧化、抗肿瘤和抗糖尿病的作用。Amarogentin 是苦味受体 TAS2R1 的激动剂,可抑制LAD-2细胞中substance P诱导的新合成的 TNF-α 的产生。Amarogentin 通过 G2/M 细胞周期的阻滞和 PI3K/Akt 信号通路诱导人胃癌细胞(SNU-16)的凋亡。Amarogentin (AG) 可与 AMP-activated protein kinase (AMPK) 的α2亚基相互作用,并激活三聚体激酶,其EC50值为277 pM。
S0923 Isoliquiritin apioside Isoliquiritin apioside (ISLA, ILA) 是一种分离自 Glycyrrhizae radix rhizome (GR) 的成分,可显著地降低PMA诱导的 matrix metalloproteinase (MMP) 的活性增加并抑制了PMA-诱导 mitogen-activated protein kinase (MAPK)NF-κB 的活化。Isoliquiritin apioside 在恶性癌细胞和EC中具有抗转移和抗血管生成的能力,并且没有细胞毒性。
S2869 Adamantane Adamantane 是一种无色结晶的、带有类似樟脑气味的化合物,首次获得是从石油中分离出的。Adamantane 可用于治疗 influenza A virus 感染。
S9690 Caerulein (FI-6934) Caerulein (Ceruletide, Cerulein, FI-6934) 是一种 cholecystokinin (CCK) receptor 的激动剂,也是一种安全有效的胆囊代谢药,是小肠和胰腺外分泌的兴奋剂。
S6924 D-Luciferin sodium salt D-Luciferin (D-(-)-Luciferin, Firefly luciferin) sodium salt 是萤光素酶的天然底物,可催化生物发光昆虫产生光。
S3290 Procyanidin B2 (PCB2) Procyanidin B2 (PCB2) 是一种存在于常见食品中的天然类黄酮,具有抗炎、抗氧化和抗癌活性。Procyanidin B2 可激活 PPARγ 并诱导小鼠巨噬细胞M2极化。Procyanidin B2 可显著抑制百草枯在大鼠模型中肺组织中 NLRP3 炎性小体的活化。
S9700 Tapinarof Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) 是一种 aryl hydrocarbon receptor (AhR) 的天然激动剂,可诱导永生化角质形成细胞(HaCaT)中AhR的核易位,EC50值为0.16 nM。Tapinarof 可以以剂量依赖的方式诱导CD4+ T细胞的凋亡,其IC50值为5.2 μM。
S6919 Brevilin A Brevilin A (6-O-Angeloylplenolina) 是一种从Centipeda minima分离得到的倍半萜内酯,是 STAT3 的选择性抑制剂,可通过阻断JAKs酪氨酸激酶结构域 JH1 来减弱 JAKs 的活性。Brevilin A 可通过线粒体途径和 PI3K/AKT/mTOR 失活来诱导结肠腺癌细胞CT26的凋亡和自噬。
S0924 Pteryxin Pteryxin ((+)-Pteryxin) 是一种在 Apiaceae 伞形科中发现的二氢吡喃香豆素衍生物,也是一种有效的 butyrylcholinesterase (BChE) 的抑制剂,IC50值为12.96 μg/ml。Pteryxin 可抑制LPS诱导的小鼠腹膜巨噬细胞中 nitric oxide 的产生,其IC50值为20 μM。Pteryxin 具有治疗阿尔茨海默氏病 (AD) 的潜力。
S0973 Wilforgine Wilforgine 是 Tripterygium wilfordii Hook. F.中主要的生物活性倍半萜生物碱之一,可在M. separata larvae的肌肉中诱导显微结构和超微结构变化,其发挥作用的位置是肌肉系统中的 calcium receptors or channels
S3254 Plantagoside Plantagoside 是一种从 Plantago asiatica 的种子中分离出的黄烷酮葡糖苷,是一种特异性的、非竞争性的 alpha-mannosidase 的抑制剂,IC50值为5 μM。
S3253 Xylobiose Xylobiose (1,4-β-D-Xylobiose, 1,4-D-Xylobiose) 是由木糖单体形成的二糖,是一种天然的底物,可以被来源于 Selenomonas ruminantium (SXA)的β-D-木糖苷酶/α-L-阿拉伯呋喃糖苷酶水解。
S3252 Xylotriose Xylotriose (1,4-b-D-Xylotriose, 1,4-beta-D-xylotriose) 是一种天然的木寡糖底物,可以被来源于 Selenomonas ruminantium (SXA)的催化有效的β-D-木糖苷酶水解。
S3222 Raspberry ketone glucoside Raspberry ketone glucoside (RKG) 是来源于树莓果实的天然产物,是一种抗氧化剂antioxidant,对黑色素 melanin 的合成具有抑制作用。
S3223 L-Quebrachitol L-Quebrachitol (L-QCT) 是可从许多植物中分离出来的天然产物,促进增殖和细胞DNA合成。L-Quebrachitol 可上调 bone morphogenetic protein-2 (BMP-2)runt-related transcription factor-2 (Runx2)mitogen-activated protein kinase (MAPK) 相关调控基因和 Wnt/β-catenin 信号通路,同时下调 nuclear factor-κB(NF-κB) 配体 (RANKL) 受体激活剂的mRNA水平。
S3226 Dehydroabietic acid Dehydroabietic acid (DAA, DHAA) 是一种天然的二萜树脂酸,衍生自针叶植物(如 PinusPicea)通过抑制 SrcSykTAK1 介导的通路来产生抗炎活性。
S3278 Kaempferol-3-O-neohesperidoside Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) 是一种从Primula latifolia Lapeyr. 和 Primula vulgaris Hudson 的叶提取物中分离出的类黄酮,通过 PI3K - GSK-3 信号通路和 MAPK - PP1 通路来刺激大鼠比目鱼肌中的糖原合成 glycogen synthesis
S3289 Daphnoretin Daphnoretin (Dephnoretin, Thymelol) 是一种从Wikstroemia indica C.A. Mey.中提取的具有生物活性的化合物,是 protein kinase C (PKC) 的激活剂。Daphnoretin 通过调节 Akt 信号通路的活性,来抑制肿瘤细胞的增殖、侵袭和迁移,促进其凋亡。
S3295 Taxifolin 7-rhamnoside Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside) 是一种从 Hypericum japonicum 中分离出的类黄酮,其具有对抗耐甲氧西林金黄色葡萄球菌 (MRSA).的临床分离株的抗菌活性。
S3224 Cinobufagin Cinobufagin (Cinobufagine) 是 Venenum Bufonis 的活性成分,可抑制肿瘤发展。Cinobufagin 可提高 ATMChk2 并降低 CDC25CCDK1cyclin B。Cinobufagin 抑制 PI3KAKTBcl-2,同时增加裂解的 caspase-9caspase-3 水平。由此诱导细胞周期停滞在G2/M期及凋亡。
S3230 L-Fucitol L-Fucitol (1-Deoxy-D-galactitol) 是一种分离自 Myristica fragrans (Nutmeg) 的半乳糖醇类似物,可抑制大肠杆菌K12的半乳糖醇阳性菌株。
S3236 Mesaconitine Mesaconitine 是Aconiti tuber附子块茎中的附子生物碱之一,通过从细胞外空间流入Ca2+来增加内皮细胞中的[Ca2+]i水平。
S3238 Resibufogenin Resibufogenin (Bufogenin, Recibufogenin) 是huachansu华蟾素中具有抗癌作用的成分,通过上调 receptor-interacting protein kinase 3 (RIP3) 和磷酸化 mixed lineage kinase domain-like protein 的Ser358位点来触发坏死病。Resibufogenin 可通过诱导 reactive oxygen species (ROS) 积累发挥细胞毒性作用。Resibufogenin 可诱导凋亡和 caspase-3caspase-8 活性。Resibufogenin 增加 Bax/Bcl-2 表达,并抑制 cyclin D1cyclin EPI3Kp-AKTp-GSK3ββ-catenin 的蛋白表达。
S3245 Nodakenetin Nodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素,可抑制 α-glucosidasePTP1Brat lens aldose reductase (RLAR)AChEBChEβ-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 BaxBcl-2 的蛋白质表达,并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。
S3251 Goitrin Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) 是板蓝根 Radix isatidis 的主要成分之一,广泛用于治疗发烧、清热的传统中药。Goitrin 具有抗病毒和抗内毒素活性。
S3262 Scopolin Scopolin 是一种从 Arabidopsis thaliana (Arabidopsis) 中分离的香豆素,它通过激活 SIRT1 介导的信号级联反应来减轻肝脏脂肪变性,SIRT1介导的信号通路是脂质稳态的有效调节剂。
S3267 Nicotiflorin (Kaempferol-3-O-rutinoside) Nicotiflorin (Kaempferol-3-O-rutinoside)是从 Carthamus tinctorius 中提取的黄酮,可改变受伤神经元的形状和结构,减少凋亡细胞,下调 p-JAK2p-STAT3caspase-3Bax 的表达,并降低Bax免疫反应性,并增加 Bcl-2 蛋白表达和免疫反应性。
S3271 Caudatin Caudatin (Cauldatin),一种来源于 Cynanchum auriculatum (C. auriculatum) 的C-21类固醇激素,可通过触发细胞周期阻滞和凋亡,在体外和体内均有效地抑制人神经胶质瘤的生长。
S3273 Hypericin Hypericin (Hyp, HY) 是一种在 common St. John's Wort (Hypericum species) 中发现的天然物质,具有抗抑郁、抗肿瘤和抗病毒 (人类免疫缺陷病毒HIV和丙型肝炎病毒HCV) 活性。Hypericin 对 MAO (monoaminoxidase)PKC (protein kinase C)dopamine-beta-hydroxylasereverse transcriptasetelomeraseCYP (cytochrome P450)
S3291 Myristicin Myristicin (Myristicine) 是一种在 Myristica fragrans 的种子 Nutmeg 中的萜烯样活性成分,是 monamine oxidase (MAO) 的弱抑制剂和 CYP1A2 的机理抑制剂。
S3296 Hispidulin Hispidulin (Dinatin) 是一种在许多传统中草药中存在的天然活性成分,对癌蛋白激酶 Pim-1 具有抑制活性,其IC50值为2.71 μM。Hispidulin 通过 mitochondrial dysfunction 来诱导凋亡,并可抑制HepG2癌细胞中的 P13k/Akt 的信号通路。Hispidulin 通过激活 AMPK 信号通路发挥抗骨质疏松和骨吸收减弱的作用。
S3300 Desoxyrhaponticin Desoxyrhaponticin (DC, DES) 是一种来自中国传统的营养食品 Rheum tanguticum Maxim. ex Balf. (rhubarb) 的对称二苯代乙烯配糖体,是 fatty acid synthase (FAS/FASN) 的抑制剂。Desoxyrhaponticin (DC, DES) 也是竞争性的 glucose 摄取的抑制剂,在兔肠膜囊泡和大鼠肠翻肠中的IC50值分别为148.3 μM和30.9 μM。Desoxyrhaponticin 对人癌细胞具有凋亡作用。
S3301 Cynarin Cynarin (Cynarine) 是一种来自artichoke洋蓟的植物化学成分,具有多种药理特性,包括自由基清除、抗氧化剂、抗组氨酸和抗病毒活性。Cynarin 可阻断T细胞受体的 CD28 和抗原呈递细胞的 CD80 之间的相互作用。Cynarin 可触发 Nrf2 的核易位,恢复 glutathione (GSH)reactive oxygen species (ROS) 的平衡,并抑制线粒体去极化。
S3305 Medicagenic acid Medicagenic acid (Castanogenin) 是一种分离自 Herniaria glabra L. 的具有生物活性的三萜类五环糖苷,对 xanthine oxidase、collagenase、elastase 和 tyrosinase 具有低抑制活性。
S3240 Phaseoloidin Phaseoloidin 是一种来自烟草毛状线虫的高纯酸糖苷,有助于植物抵抗鳞翅目草食动物。Phaseoloidin 具有抗补体 anti-complement 的作用。
S3242 Loureirin B Loureirin B (LB, LrB),是从Dracaena cochinchinensis中提取的类黄酮,是 PAI-1 的抑制剂,其IC50值为26.10 μM。Loureirin B 可下调TGF-β1刺激的成纤维细胞中的 p-ERKp-JNK。Loureirin B 主要通过增加Pdx-1、MafA、细胞内ATP水平来促进胰岛素分泌,抑制 KATP 电流,Ca2+ 进入细胞内。
S3246 Picfeltarraenin IB Picfeltarraenin IB 是从 Picriafel-terrae 中分离出的葫芦素糖苷,是 acetylcholinesterase (AChE) 的抑制剂。Picfeltarraenin IB 可用于治疗疱疹感染,癌症和炎症。
S3260 3'-hydroxy Puerarin 3'-hydroxy Puerarin 是从 Puerariae Lobatae Radix 中分离出的异黄酮。
S3264 Atractyloside potassium salt Atractyloside potassium salt (ATR potassium salt) 是一种从 Xanthium sibiricum (Cang'erzi) 果实中分离出的毒性二萜糖苷,是一种有效的、特异性的 mitochondrial ADP/ATP carriers的抑制剂。Atractyloside potassium salt 可抑制大鼠心脏线粒体膜的 chloride channels
S3269 Acetylcorynoline Acetylcorynoline 是衍生自中草药 Corydalis bungeana 的主要生物碱成分,具有抗炎特性。Acetylcorynoline 可能通过降低 egl-1 的表达来抑制细胞凋亡通路,并增加 rpn5 的表达来增强 proteasomes 的活性。
S3270 Genipin 1-O-beta-D-gentiobioside Genipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) 是从栀子 Gardenia jasminoides Ellis 中分离到的一种生物活性类环烷苷,具有保肝、抗炎、抗氧化和抗血栓形成的功能。
S3275 Senkyunolide I Senkyunolide I (SEI, SENI) 是一种从 Ligusticum chuanxiong 中提取的口服活性化合物,具有止痛、抗偏头痛、神经保护、抗氧化和抗凋亡的活性。Senkyunolide I (SEI, SENI) 可上调 Erk1/2 的磷酸化,并诱导 Nrf2 的核易位,伴随着HO-1和NQO1的表达增强。Senkyunolide I (SEI, SENI) 可提高 Bcl-2/Bax 的比例,并抑制裂化的 caspase 3caspase 9 的表达。
S3297 Hosenkoside A Hosenkoside A 是从 impatiens balsamina 种子中分离出来的一种生物活性的葡糖苷。
S3303 Cyperotundone Cyperotundone (CYT) 是在 Chuanxiong Rhizoma 和 Cyperi Rhizoma (CRCR) 中治疗偏头痛的有效成分。
S3307 Galangin 3-methyl ether Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin) 分离自 Lychnophora markgravii 的地上部分,具有很强的抗细菌和抗真菌作用。
S3308 Caftaric acid Caftaric acid (CA, Caffeoyl tartaric acid) 是一种具有抗氧化和抗炎作用的天然产物。
S3276 Hosenkoside K Hosenkoside K 是从 impatiens balsamina 种子中分离出来的一种生物活性的葡糖苷。
S6906 Capric acid Capric acid (DA, Decanoic acid, Decylic acid) 是在椰子油和棕榈油中天然存在的中链甘油三酯的成分,可通过直接抑制 AMPA receptor 来控制癫痫发作。癸酸还是 PPARs 的调节配体。由于其特殊的熔化范围,产品可能是固体、液体或半固体状态。
S6899 Licochalcone D Licochalcone D (Lico D, LCD, LD) 是一种从中草药甘草 Glycyrrhiza inflata 中分离出的类黄酮,具有抗氧化、抗炎和抗癌的特性。Licochalcone D 可抑制LPS信号通路中NF-κB p65的磷酸化。Licochalcone D 可抑制 JAK2EGFRMet (c-Met) 活性,并诱导ROS依赖性的凋亡。Licochalcone D 还可诱导 caspases 的活化和 poly (ADP-ribose) polymerase (PARP) 的裂解。
S3265 9''-Methyl salvianolate B 9''-Methyl salvianolate B (9'-methyllithospermate B, 9'-Methyl lithospermate B, 9'''-Methyl salvianolate B) 是丹参 Radix Salviae Miltiorrhizae 的乙醇提取物中的活性成分。
S6885 Ailanthone Ailanthone (AIL, Δ13-Dehydrochaparrinone) 是一种来自臭椿Ailanthus altissima的天然通过抗肝癌(HCC)成分,可通过降低 cyclinsCDKs 的表达、提高 p21p27 的表达来诱导G0/G1期细胞周期阻滞。Ailanthone 可触发DNA损伤,其特征为 ATM/ATR 通路的激活。Ailanthone 可在Huh7细胞中诱导线粒体介导、涉及 PI3K/AKT 信号通路的细胞凋亡。Ailanthone 也是全长 Androgen Receptor (AR-FL)和组成型活性截断AR剪接变体(AR-Vs, AR1-651)的抑制剂,对应的IC50值分别为69 nM和309 nM。
S0917 Allosecurinin Allosecurinine (Phyllochrysine) 是一种从 M.indicaM.discoidea 分离的具有抗真菌活性的Securinega生物碱。
S0906 6-Methoxydihydrosanguinarine 6-Methoxydihydrosanguinarine 是一种从 M. cordata 果实中分离出的生物碱,6-Methoxydihydrosanguinarine 对 MCF-7 和 SF-268 细胞系具有强的细胞毒性,IC50 值分别为 0.61 μM 和 0.54 μM。
S3287 Rosamultin Rosamultin 是一种从 Potentilla anserina L. 分离的19 α-hydroxyursane-type三萜,可抑制 HIV-1 protease。Rosamultin 对H2O2诱导的氧化损伤和细胞凋亡具有保护作用。
S6340 Guanidinoacetic acid Guanidinoacetic acid (Guanidino acetic acid, GAA, Glycocyamine, Guanidinoacetate) 正在作为一种饮食制剂被研究。Guanidinoacetic acid 对体育锻炼的男性和女性均具有潜在的人体工程学益处。
S3220 Trigonelline Trigonelline (Trigenolline) 是一种植物生物碱,是咖啡和葫芦巴的主要成分,具有抗脱粒、抗糖尿病、抗氧化、抗炎和神经保护的作用。 Trigonelline 可抑制FcεRI介导的细胞内信号通路,例如 PLCγ1PI3KAkt 的磷酸化。Trigonelline (Trigenolline) 还可抑制RBL-2H3细胞中 microtubule 的形成。
S3235 Sinapine Sinapine 是一种从十字花科物种的种子中分离出来的生物碱,具有抗氧化、抗肿瘤和放射防护的作用。Sinapine 通过下调 P-glycoprotein 来抑制Caco-2细胞的增殖。
S3261 Myrislignan Myrislignan 是一种分离自Myristica fragrans Houtt的木脂素并具有抗炎活性。Myrislignan 可抑制 interleukin-6 (IL-6)tumour necrosis factor-α (TNF-α)。Myrislignan 剂量依赖性地抑制LPS刺激的巨噬细胞中 inducible NO synthase (iNOS)cyclooxygenase-2 (COX-2) 的表达。Myrislignan 可抑制 NF-κB 信号通路的激活。
S3279 Polyphyllin B (Formosanin C) Polyphyllin B (Formosanin C, FC) 是一种从Paris formosana分离得到的薯蓣皂苷,也是一种具有抗肿瘤活性的免疫调节剂。Polyphyllin B (Formosanin C, FC) 可诱导凋亡。
S3280 Linderene Linderene (Lindenenol) 是从Lindera pulcherrima中分离出来的呋喃倍半萜类,具有抗菌和抗氧化活性。
S3281 Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside (Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobiosiden, Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside) 是一种Descurainiae Semen的活性成分。
S3298 Caulophylline (N-Methylcytisine) Caulophylline (N-Methylcytisine, Caulophyllin, NMC) 是一种具有抗炎活性的三环喹喔啉生物碱。Caulophylline 可与鱿鱼视神经节的 nicotinic acetylcholine receptors (nAChR) 结合,Kd值为50 nM。Caulophylline 可显著地降低 myeloperoxidase (MPO) 的活性,并通过抑制 IκBIKK 磷酸化来阻断 NF-κB 的活化。
S3302 β,β-dimethyl-acryl-alkannin β,β-dimethyl-acryl-alkannin (AN-I, β,β-Dimethylacrylalkannin) 是一种从 Arnebia nobilis Reichb.f. 的根中分离出来的萘醌,有潜力成为抗衰老成分。
S3304 Stylopine Stylopine ((R,S)-Stylopine, Tetrahydrocoptisine) 可降低LPS刺激引起的 nitric oxide (NO)prostaglandin E2 (PGE2)tumor necrosis factor-alpha (TNF-alpha)interleukin-1beta (IL-1beta)IL-6 的生成,以及 cyclooxygenase-2 (COX-2) 的活性。Stylopine 是 Chelidonium majus L 的叶子的主要成分。
S3306 1,1,1,1-Kestohexaose 1,1,1,1-Kestohexaose 是crested wheatgrass叶中的主要DP 6果聚糖。
S3205 Perillaldehyde Perillaldehyde (Perilladehyde, Perillal, PAE, PA) 是紫苏 Perilla frutescens(一种传统的抗氧化剂)的主要成分,可抑制BaP诱导的 AHR 的活化和 ROS 的产生,抑制 BaP/AHR 介导的 CCL2 chemokine 的释放,并激活 NRF2/HO1 抗氧化剂途径。
S3227 5,7-Dimethoxyflavone 5,7-Dimethoxyflavone (5,7-DMF) 是一种 cytochrome P450 (CYP) 3As 的抑制剂,可显著地降低肝脏中CYP3A11和CYP3A25的表达。5,7-Dimethoxyflavone (5,7-DMF) 也是一种有效的 Breast Cancer Resistance Protein (BCRP, ABCG2) 的抑制剂。5,7-Dimethoxyflavone (5,7-DMF) 是Kaempferia parviflora的主要成分之一,具有抗肥胖、抗炎和抗肿瘤作用。
S3237 Deoxyaconitine 3-Deoxyaconitine 是一种从 Aconitum Carmichaeli Debx 的根中分离出来的二萜类生物碱。
S3241 Loureirin A Loureirin A 是一种黄酮类化合物,从被称为龙血的来源于Dracaena cochinchinensis的红色树脂中提取出来。Loureirin A 可通过破坏 PI3K/Akt 信号传导来抑制血小板platelet活化。Loureirin A 可抑制 Akt 磷酸化。
S3247 Icariside I Icariside I (Icarisid I) 是 Epimedii Folium 的主要成分之一,可显着刺激细胞增殖和成骨细胞分化。
S3249 Corypalmine Corypalmine ((R)-(+)-Corypalmine),一种从 Stephania cepharantha 分离的生物碱,是 prolyl endopeptidase/oligopeptidase (PREP/POP) 的抑制剂,IC50值为128.0 μM。
S3255 Pectolinarigenin Pectolinarigenin 是 Cirsium chanroenicum 中的一种抗炎活性成分,是 cyclooxygenase-2 (COX-2)5-lipoxygenase (5-LOX) 的双效抑制剂。
S3256 Tectochrysin Tectochrysin (Techtochrysin, NSC 80687) 是Alpinia oxyphylla Miquel的主要类黄酮之一。Tectochrysin 可显著地增加DR3DR4Fas的表达,并抑制 NF-κB 的活性。Tectochrysin 可诱导细胞凋亡。
S3257 Rebaudioside B Rebaudioside B (Reb B) 是一种从甜叶菊 Stevia rebaudiana 分离的次要甜菊醇糖苷(SGs)之一,并且比许多主要SG具有更好的口感品质。
S3259 Rebaudioside D Rebaudioside D (Reb D) 是在甜叶菊 Stevia rebaudiana (Bertoni) 的叶子中发现的几种糖苷(SGs)之一,这种糖已被鉴定为潜在的甜味剂。
S3272 Steviol (Hydroxydehydrostevic acid) Steviol (Hydroxydehydrostevic acid, Hydroxy Dehydrostevic Acid, NSC 226902) 是甜味化合物甜菊糖的主要代谢产物,可抑制 CFTR 的活性,降低 AQP2 的表达并促进AQP2降解。
S3274 Glucosyl-vitexin Glucosyl-vitexin (Glucosylvitexin) 是小米中主要的C-糖基黄酮,可抑制 thyroid peroxidase (TPO) 的活性。
S3282 Rebaudioside M Rebaudioside M 是一种从甜叶菊Stevia rebaudiana Bertoni中分离的天然无热量潜在甜味剂,可应用于食品和饮料产品。
S3283 Marmesin Marmesin (S-(+)-Marmesin, (+)-Marmesin, (S)-Marmesin) 是一种具有 COX-25-LOX 双重抑制作用的天然香豆素。
S3284 Tracheloside Tracheloside 是一种从 Carthamus tinctorius 的种子中分离得到的木脂素糖苷,具有抗雌激素作用。Tracheloside 可显著地降低 alkaline phosphatase (AP)(一种雌激素诱导性标记酶) 的活性,IC50为 0.31 μg/ ml。Tracheloside 通过刺激 ERK1/2 来促进角质形成细胞的增殖。
S3285 Dihydrolycorine Dihydrolycorine 是lycorine的衍生物,它是从 Lycoris radiata 草药中分离出来的生物碱。Dihydrolycorine 可阻断腹水细胞中的蛋白质合成并在体内稳定HeLa细胞多核糖体。Dihydrolycorine 具有降压和神经保护的作用。
S3299 Demethyleneberberine Demethyleneberberine (DMB) 是黄柏Cortex Phellodendri Chinensis (CPC) 的成分,可显著地缓解体重减轻并降低 myeloperoxidase (MPO) 活性,同时显著地减少促炎细胞因子的生成,例如 interleukin (IL)-6tumor necrosis factor-α (TNF-α),并抑制 NF-κB 信号通路的激活。Demethyleneberberine (DMB) 可以通过激活 AMPK 途径改善NAFLD (非酒精性脂肪肝疾病)。
S0553 Butyl isobutyl phthalate  Butyl isobutyl phthalate (BIP) 是一种从 Laminaria japonica 的根状茎中分离出来的,α-glucosidase 的非竞争性抑制剂,其IC50值为38 μM。Butyl isobutyl phthalate 具有显著的降血糖作用和治疗糖尿病的潜力。
S3206 5a-Pregnane-3,20-dione 5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) 是一种内源性的孕酮代谢物。5a-Pregnane-3,20-dione 可使肌动蛋白actin解聚,并降低 actinvinculin 的表达。5a-Pregnane-3,20-dione 可通过影响粘附和细胞骨架分子来参与促进乳腺瘤形成和转移。
S2440 Vindesine sulfate Vindesine sulfate是一种提取自 Catharanthus roseus的长春花生物碱,是一种有效的有丝分裂 mitosis 的抑制剂,并具有抗肿瘤的活性。Vindesine 与有丝分裂纺锤体的微管蛋白结合,可导致微管结晶和有丝分裂阻滞或细胞死亡。
S0949 Cucurbitacin IIb Cucurbitacin IIb (CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A) 可抑制 STAT3JNKErk1/2 的磷酸化,而增强 IκBNF-κB 的磷酸化,阻止 NF-κB 的核易位并降低 IκBαTNF-α 的mRNA表达水平。Cucurbitacin IIb 是从Hemsleya amabilis 中分离出来的,具有抗炎活性并可诱导凋亡。
S6852 Gossypol Gossypol (BL 193) 是一种从棉籽和根中分离出来的口服活性的多酚。Gossypol 是一种 5α-reductase 13α-hydroxysteroid dehydrogenase 的有效抑制剂,在无细胞试验中,对应的IC50值分别为3.33 μM和0.52 μM。Gossypol 还可抑制BH3肽与Bcl蛋白的结合,对 Bcl-XLBcl-2 的IC50值分别为0.4 μM和10 μM。Gossypol 在各种癌细胞中可诱导凋亡和细胞的生长抑制。
S3210 3'-Hydroxy-4'-methoxyacetophenone 3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) 是一种具有消炎潜能的活性多刺疟原虫提取物。
S3213 Veratryl alcohol Veratryl alcohol (VA, Veratrole alcohol, 3,4-Dimethoxybenzyl alcohol) 是一种木质素降解真菌的次生代谢产物,是木质素过氧化物酶 Lignin peroxidase (LiP) 的天然底物。
S3214 Veratraldehyde (3,4-Dimethoxybenzaldehyde) Veratraldehyde (3,4-dimethoxybenzaldehyde, VD, VAD, VAld, Verapamil Related Compound E, Methylvanillin) 是一种香兰素的衍生物,是从薄荷,生姜,波旁香草和树莓等水果中发现并分离出来的化学物质。Veratraldehyde 由于其令人愉悦的木质香气而被广泛用作调味剂和增香剂。Veratraldehyde 还可用作氧化还原循环剂。
S3215 2-O-α-D-Glucopyranosyl-L-ascorbic acid 2-O-α-D-Glucopyranosyl-l-ascorbic acid (AA-2G),是抗坏血酸ascorbic acid (AA)的葡糖苷衍生物,在酶水解为抗坏血酸ascorbic acid后显示出维生素C的活性。AA-2G的抗肿瘤活性是由AA-2G快速水解释放的AA产生的ROS引起的。
S3203 D-Alanine D-alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) 是一种 glycine site of the N-methyl-d-aspartate (NMDA) receptor 的内源性激动剂。
S3293 Gardenoside Gardenoside 是一种从Gardenia栀子属果实中提取的天然化合物,具有保肝作用。Gardenoside 可抑制 TNF-αIL-1βIL-6NFκB 的活化。Gardenoside 还对游离脂肪酸(FFA)诱导的细胞脂肪变性具有抑制作用。Gardenoside 可通过调节 P2X3P2X7 受体来减轻慢性压迫性损伤大鼠的疼痛。
S3292 Falcarindiol Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) 是一种天然的聚乙炔化合物,存在于伞形科的许多植物中。Falcarindiol 可抑制LPS刺激的 inducible nitric oxide synthase (iNOS)tumor necrosis factor alpha (TNFα)interleukin-6 (IL-6)interleukin-1 beta (IL-1β) 的表达。Falcarindiol 可减弱LPS诱导的 JNKERKSTAT1STAT3 信号分子的激活。
S3263 Agarotetrol Agarotetrol 是一种在沉香树的水提取物中高浓度的酮衍生物。Agarotetrol 可通过加热产生LAC而有助于沉香木的香味。
S3216 Uridine 5'-diphosphoglucose disodium salt Uridine-5'-diphosphoglucose (UDPG, UDP-Glc, UDP-D-Glucose, UDP-α-D-Glucose) 可激活神经免疫系统GPCR P2Y(14) receptor。Uridine-5'-diphosphoglucose 是动物组织和某些微生物中含葡萄糖的寡糖,多糖,糖蛋白和糖脂的前体。
S7904 2',3'-cGAMP Sodium Salt 2',3'-cGAMP Sodium Salt (2'-3'-cyclic GMP-AMP Sodium)是响应哺乳动物细胞质中的DNA产生的,并能以高亲和力结合 STING,且有效地诱导 interferon-β (IFNβ)。2',3'-cGAMP 结合 STING 的Kd值为3.79 nM。
S6630 Dimethylcurcumin (ASC-J9) Dimethylcurcumin (ASC-J9, Dimethyl curcumin, GO-Y025)是一种 androgen receptor (AR) 降解促进剂,可通过降解全长和剪接变异体的雄激素受体来抑制去势抵抗性前列腺癌的生长。
S2766 Glycerol Glycerol (Glycerin)是一种透明,无色和粘稠的液体,可用作润肤剂,溶剂或甜味剂。Glycerol 可改变了聚丙烯酰胺核蛋白凝胶的分离特性,防止电泳过程中核小体和其他蛋白质-DNA 复合物的解离。
S8587 Withaferin A (WFA) Withaferin A (WFA)可通过对硫代烷基化敏感的氧化还原机制阻止肿瘤坏死因子诱导的IκB激酶β的激活,从而有效地抑制 NF-κB 激活。Withaferin A 可与中间丝状体蛋白(IF) vimentin 结合,并具有抗肿瘤和抗血管生成活性。Withaferin A 是一种从 Withania somnifera 分离的甾体内酯。
S2653 9-amino-CPT (9-Aminocamptothecin) 9-amino-CPT (9-Aminocamptothecin, 9-AC, Aminocamptothecin, 9-amino-20(S)-camptothecin)是一种 Topoisomerase I 抑制剂并具有有效的抗癌活性。9-amino-CPT (9-Aminocamptothecin) 是喜树碱的一种具有活性的、不溶于水的衍生物。
S8620 6-Diazo-5-oxo-L-norleucine 6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON)是一种从链霉菌中分离出来的抗生素,一种 glutaminase 的拮抗剂对cKGA(肾脏型谷氨酰胺酶)的IC50值约为1 mM。6-Diazo-5-oxo-L-norleucine 具有止痛,抗菌,抗病毒和抗癌的特性。
S2654 Neoruscogenin Neoruscogenin 是从 R. rhizoma 中分离的天然皂苷元。Neoruscogenin 是一种有效且高亲和力的 RAR-related orphan receptor alpha (RORα or nuclear receptor NR1F1) 的激动剂。
S8970 HQNO HQNO (2-heptyl-4-hydroxyquinoline-N-oxide)是一种由 P. aeruginosa 分泌的天然喹诺酮。HQNO 也是一种 electron transport chain 的有效抑制剂,其对呼吸链的泛醇-亚铁色素c氧化还原酶区段(Complex III)的Kd值为64 nM。在50 μM menadione存在下,HQNO 还是细菌和线粒体的 Type II NADH : quinone oxidoreductase (NDH-2) 的抑制剂,在50 μM menadione存在的条件下,其IC50值为7.3 μM。
S7895 Thapsigargin Thapsigargin 是一种有效的、非竞争性的 the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) 的抑制剂,对carbachol诱导的[Ca2+]i瞬变在存不存在KCl预刺激条件下的IC50值分别为0.353 nM和0.448 nM。Thapsigargin 可诱导细胞凋亡。Thapsigargin 提取自植物Thapsia garganica
S7905 3',3'-cGAMP 3',3'-cGAMP (3',3'-cyclic GMP-AMP, Cyclic GMP-AMP, cGAMP)可激活内质网(ER)内源性受体 stimulator of interferon genes (STING) ,从而诱导抗病毒状态和I型IFN的分泌。
S7821 Bufalin Bufalin (BF)是 类固醇受体共激活剂 SRC-3、SRC-1Na+/K+-ATPase 的有效抑制剂。Bufalin 可与Na+/K+-ATPase的亚基α1、α2和α3结合,其Kd值分别为42.5 nM、45 nM和40 nM。Bufalin 是一种从中药蟾酥中分离出来的,具有抗癌活性的,类地高辛免疫反应的主要成分。
S7862 Rottlerin Rottlerin (Mallotoxin, NSC 56346, NSC 94525)是一种从 Mallotus Philippinensis 纯化出来的天然化合物,一种特效的 Protein kinase 的抑制剂,对PKCδ(来自杆状病毒感染的Sf9昆虫细胞)、PKCδ(来自猪脾)和CaM kinase III的IC50值分别为3 μM、6 μM和5.3 μM。Rottlerin 还可以抑制PKCα、PKCγ、PKCβ、PKCη、CKII和PKA,其IC50值分别为30 μM、40 μM、42 μM、82 μM、30 μM和78 μM。
S2447 Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222) Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) 是一种有效的微管蛋白聚合抑制剂,IC50为3.4 μM。
S6790 Ellipticine hydrochloride Ellipticine Hydrochloride (NSC 71795, PZE)是一种有效的 DNA topoisomerase II 的抑制剂,并通过其与 cytochromes P450 (CYP)peroxidases 的氧化作用介导形成共价DNA加合物。Ellipticine Hydrochloride 是从澳大利亚的夹竹桃科常绿乔木中分离出来的具有抗肿瘤活性的天然产物。
S8964 Actinomycin D (Dactinomycin) Actinomycin D (Dactinomycin, Act D, RASP-101)是一种从链霉菌属的土壤细菌中分离出来的重要的多肽抗生素。Actinomycin D (Dactinomycin) 可抑制 DNA repair,并使 cell cycle 停滞在G1期,其IC50值分别为0.42 μM和0.4 nM。Actinomycin D (Dactinomycin) 是 autophagy 的激活剂,可在高危慢性淋巴细胞性白血病中诱导p53依赖性细胞的死亡并延长生存期。此产品为危化品(急性毒性/易燃/皮肤腐蚀),请在穿戴防护面罩、防护手套和防护服后使用。
S2288 Rubitecan Rubitecan (9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000) 是一种 拓扑异构酶I topoisomerase I 的抑制剂,从中国喜树的树皮和叶子中提取。Rubitecan 也是一种具有抗肿瘤活性的口服喜树碱。
S2009 Indirubin-3'-monoxime Indirubin-3'-monoxime (Indirubin-3'-oxime)是一种选择性的CDK抑制剂,对CDK1-cyclinB, CDK2-cyclinA, CDK2-cyclinE, CDK4-cyclinD1, CDK5-p35的IC50分别为 0.18 μM, 0.44 μM, 0.25 μM, 3.33 μM, 0.065 μM。Indirubin-3'-monoxime是一种直接、选择性的5-lipoxygenase抑制剂,IC50为7.8-10 µM。
S1031 3-Hydroxybutyric acid (BHB) 3-Hydroxybutyric acid (BHB)是一种在I型糖尿病中升高的小分子代谢产物。
S2342 Phloretin (RJC 02792) Phloretin (RJC 02792, NSC 407292, Dihydronaringenin)是一种二氢查尔酮,含有多元酚。
S9440 Naringenin chalcone Naringenin chalcone (Chalconaringenin, Isosalipurpol, trans-2'4'6'4-tetrahydroxychalcone) is the main active component of tomato skin extract, has been proposed as an antioxidant, an anti-inflammatory, and a regulator of fat and sex hormone metabolism.
S2325 Morin Hydrate Morin hydrate (Aurantica) 是一种化学化合物,用来检测溶液中的铝或锡的存在,因为Morin hydrate与铝或锡可以形成特有的荧光配位络合物。
S6670 GPNA (L-γ-Glutamyl-p-nitroanilide) GPNA (L-γ-Glutamyl-p-nitroanilide)是一种有效的谷氨酰胺 (Gln) 转运蛋白ASCT2(SLC1A5) 的选择性抑制剂,Ki为55 µM。
S2210 Sphingosine 鞘氨醇,Sphingosine (2-amino-4-trans-octadecene-1,3-diol, C18 Sphingosine),是具有不饱和烃链的18个碳原子的氨基醇,它形成鞘脂的主要部分,鞘脂是一类细胞膜脂质,其中包括鞘磷脂,一种重要的磷脂。
S6674 Cytosporone B Cytosporone B是天然存在的核孤儿受体Nur77(NR4A1) 激动剂,EC50为0.278 nM。
S6474 3,5-diiodo-L-thyronine (3,5-T2) 3,5-diiodo-L-thyronine (3,5-T2, NSC 90469)是甲状腺激素的内源性代谢产物。 3,5-Diiodo-l-thyronine是治疗肥胖和肝脏脂肪变性的潜在降血脂药。此产品溶解度不佳,细胞实验请谨慎选择!
S9218 Phytolaccagenin Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae.
S6653 Nigericin sodium salt Nigericin sodium salt是从Streptomyces hygroscopicus衍生的抗生素,通过充当H+,K+和Pb2+的离子载体起作用。Nigericin可以激活NLRP3炎性体以诱导促炎和免疫刺激过程。
S3911 Veratramine Veratramine (NSC 17821, NSC 23880), a major alkaloid from Veratrum nigrum L., has distinct anti-tumor and anti-hypertension effects. It is a good membrane permeant, undergoes rapid passive diffusion, and has a good stability in the gastrointestinal tract during its absorption.
S9403 Ecliptasaponin A Ecliptasaponin A, a natural triterpenoid glucoside, has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-mesenchymal transition.
S3928 Baccatin Ⅲ Baccatin Ⅲ is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It exhibits immunomodulatory and anticancer chemotherapeutic activities.
S4938 Cedrol Cedrol是一种天然存在的倍半萜烯醇,是有效的、竞争性的抑制剂,抑制CYP2B6介导的安非他酮羟化酶(bupropion hydroxylase),Ki值为0.9 μM。它还能抑制CYP3A4介导的咪达唑仑羟基化,Ki为3.4 μM。对CYP2C8, CYP2C9和CYP2C19的活性仅有微弱的抑制作用。
S3942 Cardamonin Cardamonin (Alpinetin chalcone)天然存在于良姜属物种的果实中,具有抗炎和抗肿瘤活性。它是一种新型的hTRPA1离子通道拮抗剂,IC50为454 nM,而不与TRPV1和TRPV4相互作用。
S3756 Methyl salicylate Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.
S3763 Cinnamaldehyde Cinnamaldehyde is a flavonoid that is naturally synthesized by the shikimate pathway. Its supplementation can improve glucose and lipid homeostasis in diabetic animals; a TRPA1 agonist.
S4787 Methyl syringate Methyl syringate (Syringic Acid Methyl Ester), a plant phenolic compound, is a specific and selective TRPA1 agonist.
S3867 (E)-Cardamonin (E)-Cardamonin (Alpinetin chalcone, cardamomin) is a naturally occurring chalcone with strong anti-inflammatory activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-κB inhibitor.
S4714 (-)-Menthol (-)-Menthol (L-Menthol, Levomenthol, Menthomenthol, Menthacamphor) 是薄荷醇的左旋异构体,常被用作冷却剂,可激活TRPM8。
S2332 Neohesperidin Neohesperidin (NSC 31048) 是一种抗氧化剂,在1,1-diphenyl-2-picryldydrazyl(DPPH)自由基清除测定中,IC50为22.31 μg/ml。
S5755 Methyl Eugenol Methyl eugenol (4-allylveratrole, eugenyl methyl ether, O-methyleugenol), as a constituent in leaves, fruits, stems, and/or roots, is used as a flavoring agent, as a fragrance and as an anesthetic in rodents.
S2935 Nicotinamide Riboside Chloride Nicotinamide Riboside Chloride是烟酰胺核糖(NR)的氯化物盐形式。NR是维生素B3的衍生物,可作为作为NADNAD+的前体。
S3607 Sarsasapogenin Sarsasapogenin (SAR, Parigenin)是一种甾体皂甙元,能够诱发ROS的产生并激活unfolded protein response (UPR)信号通路。SAR能够有效地抑制NF-κBMAPK的激活,在LPS刺激的巨噬细胞中抑制IRAK1、TAK1和IκBα的磷酸化。
S2425 Apocynin Apocynin是一种选择性NADPH氧化酶抑制剂,IC50 为10 μM.
S6751 Brevianamide F Brevianamide F, belonging to a class of naturally occurring 2,5-diketopiperazines, is the simplest member and the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by the fungi A.fumigates and Aspergillus sp..
S6359 Purine Purine是一种杂环芳香有机化合物,在DNA和RNA中均发挥关键作用。它还是很多生物分子,如ATP、GTP、cAMP、NADH和辅酶A的重要组成成分。
S2353 Sapogenins Glycosides Sapogenins glycosides (Saponins)是糖苷配基或非糖类,属于天然产品Saponins部分家族。
S3627 Tryptamine Tryptamine是一种单胺生物碱,可能作为神经调节剂和神经递质发挥作用。它是hTAAR1的激动剂,还是非选择性的serotonin receptor激动剂和羟色胺-去甲肾上腺素-多巴胺释放剂(SNDRA)。
S5153 Tetrahydroberberine Tetrahydroberberine (Canadine) is an isoquinoline alkaloid with micromolar affinity for dopamine D2 (antagonist, pKi = 6.08) and 5-HT1A (agonist, pKi = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors.
S3823 Schizandrol A Schizandrol A is one of the effective components in the dried fruit of Schizandra chinensis Bail and works by increasing dopamine, a neurotransmitter, in the brain.
S5642 Homovanillic acid Homovanillic acid (Vanillacetic acid) is a major catecholamine metabolite that is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.
S9087 Tenuifolin Tenuifolin, a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.
S3937 Pterostilbene Pterostilbene is a natural dietary compound and the primary antioxidant component of blueberries. It has been implicated in anticarcinogenesis, modulation of neurological disease, anti-inflammation, attenuation of vascular disease, and amelioration of diabetes.
S6428 Wilforlide A Wilforlide A是雷公藤多甙中的活性化合物,是用于治疗自身免疫疾病的传统中药。
S5850 Vasicine Vasicine,可分离自A. vasica,是一种生物碱。它是天然的cholinesterase(胆碱酯酶)抑制剂,在临床前模型中具有抗胆碱酯酶活性,可用于阿尔茨海默病的治疗药物开发。
S7956 Brusatol Brusatol (NSC 172924),可分离自B. javanica果实,是一种NRF2抑制剂。
S3781 Ginkgolide C Ginkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. It is an activator of MMP-9.
S9513 Senkyunolide A Senkyunolide A is one of the major bioactive ingredients in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments.
S6049 (+)-(S)-Carvone (+)-(S)-Carvone是一种主要存在于香菜和莳萝种子油中的单萜,用于化妆品、食品和药品制备中。
S6700 Castor oil Castor oil是一种从蓖麻中提取的甘油三酯,经常用于实验动物的止泻生物测定。 它已被用来研究对大鼠晶状体状况的影响。 Castor oil还被用作Castor oil引起的腹泻大鼠模型的测试试剂,以研究Saccharomyces boulardii的剂量反应关系和作用机制。
S8870 Epibrassinolide Epibrassinolide是一种可从多种植物中分离而来的油菜素类固醇,减少毒性,在植物应激反应下刺激其健康生长。
S6701 Corn Oil Corn oil 是一种精炼植物油,用作脂溶性化合物(包括toxins)的输送载体。 它还用于在小鼠体内输送tamoxifen (TAM)、在大鼠体内输送curcumin以及在小鼠体内输送 [3H]retinol。
S9326 Scopolamine Scopolamine (Skopolamin) is a tropane alkaloid derived from plants of the nightshade family, specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties.
S3860 Allicin Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S6493 n-Butylidenephthalide n-Butylidenephthalide ((Z)-Butylidenephthalide, 3-Butylidenephthalide, Butylidenephthalide) 可从当归的氯仿提取物中分离出来,它具有多种生物活性,如减少心绞痛、血小板聚集、增殖、非特异性痉挛。
S6601 (±)-Equol (±)-Equol是大豆异黄酮、黄豆苷和黄豆苷元的一种代谢物。
S3687 Urea Urea (Carbonyldiamide, Ureophil) 是一种溶解度高的有机化合物,源自肝脏中由氨基酸脱氨基作用形成的氨。它是蛋白质分解代谢中的主要最终产物。
S3839 1-Deoxynojirimycin 1-Deoxynojirimycin (duvoglustat, moranolin) is a potent α-glucosidase inhibitor and most commonly found in mulberry leaves. It has therapeutic potency against diabetes mellitus.
S3190 m6A (N6-methyladenosine) m6A (N6-methyladenosine)是碱基修饰的腺苷类似物,在天然RNAs中作为稀有核苷。N6-methyladenosine(m6A)是mRNA的第五种碱基。
S2370 Ursolic Acid Ursolic acid (NSC 167406, NSC-4060, Prunol, Urson, Malol)是一种五环三萜酸,在化妆品中使用。
S6426 Hesperidin methylchalcone Hesperidin methylchalcone源于柑橘,具有强效的抗氧化活性。
S3821 Nuciferine Nuciferine (Sanjoinine E, (-)-Nuciferine, VLT 049) is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn and possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities.
S9227 Sinensetin Sinensetin (Pedalitin Permethyl ether), a natural polymethoxylated flavone, has potent antiangiogenesis activity.
S3973 L-SelenoMethionine L-SelenoMethionine (SeMet), a naturally occurring amino acid, is a major food-form of selenium. It has been used as a supplement, and exhibits some important functions like cancer prevention and antioxidative defense.
S2324 Sodium Monensin (NSC 343257) Sodium Monensin (NSC 343257)从 Streptomyces cinnamonensis中分离的, 是一种众所周知的天然的聚醚 类离子载体抗生素的代表。
S2348 Rotenone Rotenone是一种植物杀虫剂,是线粒体电子传递mitochondrial electron transport的抑制剂。Rotenone 可抑制 NADH/DB oxidoreductaseNADH oxidase,对应的IC50值分别为28.8 nM和5.1 nM。Rotenone 可通过增强线粒体活性氧的产生来诱导凋亡。
S2265 Artesunate Artesunate是一种抗疟类药,作用于小细胞肺癌细胞系H69,IC50为< 5 μM。它是一种潜在的STAT3抑制剂,在体外对癌细胞有选择性细胞毒性作用;是有效的EXP1抑制剂。
S6176 Scyllo-Inositol Scyllo-Inositol (Scyllitol, Cocositol, Quercinitol, AZD 103, Scyllo-Cyclohexanehexol)是一种天然存在的植物糖醇,在椰树中含量最为丰富。
S6292 (S)-2-Hydroxysuccinic acid (S)-2-Hydroxysuccinic acid (L-Malic acid)是天然存在的苹果酸同分异构体,主要于酸性和未成熟的水果中被发现。
S6346 L-(+)-Arabinose L-(+)-Arabinose (DL-Arabinose, Pectinose) 是一种用于鉴定、区分戊糖异构酶的底物。
S6061 DL-m-Tyrosine DL-m-Tyrosine是一种有效的、广谱的植物毒素,从某些细叶羊茅的根部流出。
S6163 Traumatic acid Traumatic acid (Trans-2-dodecenedioic acid)是一种植物激素,首次于损伤的绿豆中分离。它是一种有效的伤口愈合剂,是前列腺素合成的中间物。
S6264 Rutin hydrate Rutin (Quercetin-3-O-rutinoside, Rutoside, Sophorin) 是在多种植物如柑橘中所发现的一种配糖。
S6112 Oxalacetic acid Oxalacetic acid (Oxaloacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid)是三羧酸循环的中间物,它与乙酰辅酶A经柠檬酸合酶催化反应生成柠檬酸盐。它还参与糖原异生、尿素循环、乙醛酸循环、氨基酸合成和脂肪酸合成等过程。Oxaloacetate是Complex II的抑制剂。
S6221 Methyl cinnamate Methyl cinnamate 是花椒(Zanthoxylum armatum)的活性成分,是一种广泛使用的具有抗菌和 tyrosinase 抑制剂活性的天然香料化合物。Methyl cinnamate 通过激活3T3-L1前脂肪细胞中的 CaMKK2--AMPK 信号通路来抑制脂肪细胞分化。
S6008 p-Hydroxybenzaldehyde p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol),存在于兰花Gastrodia elataGaleola faberi和香草中,是一种羟基苯甲醛,可与NAD+和H20反应生成4-hydroxybenzoate、NADH和两质子。
S6011 Acetamide Acetamide (ethanamide, Acetic acid amide) 是一种有机化合物,可被用作塑化剂和工业溶剂。
S6018 2,3,4-Trihydroxybenzoic acid 2,3,4-Trihydroxybenzoic acid是转筋草中的酚组分,具有抗氧化活性。
S6043 3-Indoleacetonitrile 3-Indoleacetonitrile是一种植物生长激素,是光照诱导的生长素抑制性激素。
S6045 L-Arabinitol L-Arabinitol (L-lyxitol)是一种糖醇,存在于所有生物中。在很多食物如甘薯、鹿果、乌头叶菜豆和欧洲栗中都有发现。
S6047 Lactose Lactose是一种天然存在于奶及乳制品中的二糖。
S6071 3,5-Dimethoxyphenol 3,5-Dimethoxyphenol (Phloroglucinol dimethyl ether)是一种发现于红豆杉叶中的毒素代谢物。
S6076 Phenylacetylglutamine Phenylacetylglutamine is a product formed by the conjugation of phenylacetate and glutamine. It is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound.
S9564 p-Hydroxy-cinnamic Acid p-Hydroxy-cinnamic Acid在体外具有抗疟活性和体内抗骨质疏松活性。
S2254 4-Demethylepipodophyllotoxin(NSC-122819,VM-26) 4-Demethylepipodophyllotoxin (NSC-122819, VM-26, DMEP) is an antimitotic agent which binds to monomeric tubulin, preventing micro-tubule polymerization. It is a potent inhibitor of microtubule assembly.
S2442 Inosine Inosine (NSC 20262, INO 495) 是一种核苷,由次黄嘌呤通过β-N9-糖苷键结合到核糖环上形成。
S2280 Chlorogenic Acid Chlorogenic acid (NSC 407296, Heriguard) 是一种羟基肉桂酸,是天然存在的有机化合物。
S6250 L-Lactic acid L-Lactic acid是一种天然产物,可被用作食物添加剂。
S6275 (−)-β-Pinene (−)-β-Pinene (Nopinene)是存在于很多植物中的天然有机化合物。它对滨藜第三龄幼虫具有致死性(LD50 = 65 μg/larva)、抑制感染性支气管炎病毒的肤质(IC50 = 1.32 mM),在Vero细胞中毒性浓度CC50大于10 mM。
S6287 3-Methylbutanoic acid 3-Methylbutanoic acid (Isovaleric acid, Delphinic acid, 3-Methylbutyric acid, Isopentanoic acid, β-methylbutyric acid)是一种天然脂肪酸,广泛存在于多种植物和精油中。
S6296 Octanoic acid Octanoic acid (caprylic acid)天然存在于多种哺乳动物的乳汁(奶)中,是椰子油和棕榈仁油中的微量组分。它被用于生产香水酯类,也用于制作染料。
S6303 trans-2-Hexenal Trans-2-hexenal (Leaf aldehyde)是α,β不饱和羰基化合物,可保护植物免受有害物质侵染。
S5887 Khellin Khellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin)分离自阿密茴(伞形科)种子,被用于治疗多种疾病。
S2331 Neohesperidin Dihydrochalcone (Nhdc) Neohesperidin dihydrochalcone(Nhdc, NCI-c60764) 是源于柑橘类的一种人造甜味剂。
S9432 Ginkgolic Acid Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).
S9445 Ginkgolic Acid (C13:0) Ginkgolic Acid (C13:0) 是银杏中的一种天然抗龋剂,对变形链球菌(S. mutans)具有抗菌活性,并能抑制与其致龋性相关的特定毒力因子。银杏酸是一种有效的 sumoylation 抑制剂,据报道可抑制 histone acetylation transferase (HAT)
S2360 Solanesol (Nonaisoprenol) Solanesol (Nonaisoprenol, Betulanonaprenol) is a long-chain polyisoprenoid alcohol compound with inhibitory activities toward FAK. It mainly accumulates in solanaceous crops, including tobacco, tomato, potato, eggplant, and pepper plants.
S2369 Troxerutin Troxerutin 是一种黄酮醇类,是一种黄酮类化合物。
S5934 (-)-Fenchone Fenchone是苦艾酒中的组分,是茴香中的香精油。在食物和香水中,它被用做调料(香料)。
S6055 (S)-(−)-Limonene (S)-(−)-Limonene是一种发现于橘皮油中的香料单萜,天然存在于草本精油、茶树油和松节油中。
S6058 β-Caryophyllene β-Caryophyllene是一种天然存在的双环倍半萜烯,是很多精油的组分之一。它是非类固醇的抗炎药物、香料和代谢物。
S6059 cis-3-Hexen-1-ol cis-3-Hexen-1-ol (Leaf alcohol)是一种重要的芳香族化合物,用于果蔬香精和香水中,也是捕食性昆虫的引诱剂。
S6118 Terpinen-4-ol Terpinen-4-ol是一种天然存在的单萜,是茶树油的主要活性成分,具有多种生物活性如抗真菌活性。
S6150 Farnesyl Acetate (mixture of isomers) Farnesyl Acetate是一种香料化合物,可在一些食物如蓝莓中发现。
S6162 2-Octenoic acid 2-Octenoic acid (2-Octenoate)是一种正常的有机酸,由脂族醛通过肝脏微粒体氧化产生。它是天然存在于尿液和血浆中的代谢物。
S6164 (-)-Citronellal (-)-Citronellal是香茅油的组分,用于活性化合物的合成。
S6185 Arachidonic acid Arachidonic acid (Arachidonate)是非饱和必需脂肪酸,在动物和人类肝脏、脑部和腺器官脂肪中都有发现。它是前列腺素、凝血噁烷和白细胞三烯的生物合成的前体化合物。
S6208 Diethyl malonate Diethyl malonate天然存在于葡萄和草莓中,用于合成其他化合物。
S9476 Dendrobine Dendrobine是一种分离自石斛的植物碱,用于对石斛兰Dendrobium的质量控制和鉴别。
S9551 Uvaol Uvaol是一种从橄榄渣油的非甘油酯组分发现的五环三萜,具有促炎-抗炎活性。
S4792 N-Acetylneuraminic acid N-Acetylneuraminic acid (Neu5Ac, NeuAc, Acido aceneuramico, Acide aceneuramique, Acidium aceneuramicum, Sialic acid, NANA) is the predominant sialic acid found in mammalian cells. Sialic acids are negatively charged monosaccharides attached to the end of sugar chains, giving rise to a wide variety of glycoproteins and glycolipids in biological fluids and cell membranes.
S5526 β-Alanine β-Alanine (beta-Alanine, 3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.
S4676 Gluconolactone Gluconolactone是一种天然存在的聚羟基酸,具有螯合金属离子、保湿、抗氧化活性。
S5851 4'-Methoxychalcone 4'-Methoxychalcone存在于柑橘属植物中,是一种查耳酮衍生物,具有多种药理活性,如抗肿瘤和消炎活性。
S9481 Blinin Blinin可从Conyza blinii中分离,在中国的西南地区被用作民间药物。
S9557 Isobergapten Isobergapten是一种香豆素,具有调节植物生长活性。
S9560 Anisodamine Hydrobromide Anisodamine (6-Hydroxyhyoscyamine)是天然存在的阿托品(atropine)衍生物,具有消炎活性。它能抑制α1-adrenergic receptorsmAChRs
S5865 Hyaluronic acid (Hyaluronan) Hyaluronic acid (Hyaluronan)是一种带阴离子的、非硫酸化的粘多糖,在结缔组织、上皮和神经组织中广泛分布。它常用于皮肤护理。
S9193 Aristolochic acid A Aristolochic acid A (Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736)是一种致癌、致突变和具有肾毒性的试剂,来源于马兜铃科的开花植物。Aristolochic acid A 可显著降低 activator protein 1 (AP-1)nuclear factor-κB (NF-κB) 的活性。
S9563 Evodine Evodine是一种天然产物(源于吴茱萸),在中国药典中被记载作为吴茱萸质量评估的生物标志物。Evodine 也是一种有效的 P-gp 的抑制剂。
S9554 Bakkenolide A Bakkenolide A (Fukinanolid)分离自毛裂蜂斗菜,具有抗癌活性,可对炎性细胞因子的形成发挥保护作用。
S9552 Farrerol Farrerol是杜鹃花中一种重要的活性成分,具有抗氧化和消炎活性。
S9487 Praeruptorin C Praeruptorin C是源于白花前胡干燥根的天然产物,具有抑制破骨细胞形成和吸收的作用。它常常在中药中被用于治疗上呼吸道感染,是解热、镇咳和促黏液溶解的试剂。
S9484 Darutoside Darutoside源于植物提取物,通过减少炎症反应和修复胶原发挥有效的再生活性。
S9480 Raspberry Ketone Raspberry ketone (p-Hydroxybenzyl acetone, Frambinone, Oxyphenylon, Rheosmin, Rasketone)是一种天然存在的酚类化合物,是红莓中的主要芳香化合物。
S9473 Nuzhenide Nuzhenide (Specnuezhenide)是橄榄仁中的重要成分,属于糖脂类。
S9474 Acetylharpagide Acetylharpagide是来源于金疮小草(Ajuga decumbens)的一种单体化合物,广泛用于治疗传染性和炎症性疾病。
S5846 Apocarotenal Apocarotenal是一种类胡萝卜素,可存在于菠菜和柑橘类水果中,是维他命A的前体。
S9475 Hupehenine Hupehenine是来源于湖北贝母鳞茎的甾体生物碱,具有抑制乙酰胆碱、拮抗毒蕈碱性受体、抑制胆碱酯酶的潜力。
S9479 Complanatoside A Complanatoside A是分离自沙苑子(Astragalus complanatus)中的一种黄酮苷,可被用作沙苑子的质量控制指标。
S9488 Praeruptorin D Praeruptorin D是前胡中的成分,具有抗肿瘤和消炎活性。
S9491 (+)-Guaiacin (+)-Guaiacin存在于草药和香料中,属于木脂素类。
S9555 Vincristine Vincristine (Leurocristine, NSC-67574, 22-Oxovincaleukoblastine) 是长春花中的生物碱,具有抗肿瘤活性。Vincristine 可抑制有丝分裂纺锤体中的微管 microtubule 形成,其结合微管的Ki值为85 nM。
S9562 Pomolic acid Pomolic acid是一种分离自野鸦椿(Euscaphis japonica)的五环三萜,可有效地抑制细胞生长和诱导凋亡。
S9192 Vitexin Vitexin (Apigenin-8-C-glucoside), an naturally occuring apigenin flavone glycoside, acts as a platelet aggregation and alpha-glucosidase inhibitor and shows antineoplastic activity.
S3964 Mucic Acid Mucic Acid (Schleimsaure, Saccharolactic acid, Tetrahydroxyadipic acid, D-Glucaric acid, Galactaric acid) is the dicarboxylic sugar acid resulting from oxidation glactose with dilute nitric acid. It is a substrate of galactarate O-hydroxycinnamoyltransferase.
S5928 Zerumbone Zerumbone,分离自姜科植物,是一种天然存在的膳食化合物,具有多种生化活性,如抗增殖、抗氧化、消炎和抗癌活性。
S5794 Glycochenodeoxycholic acid Glycochenodeoxycholic acid (Glycochenodeoxycholate, Chenodeoxycholylglycine, Glycine chenodeoxycholate)是由鹅去氧胆酸盐和甘氨酸在肝脏中形成的胆汁盐。它是一种去垢剂,能溶解脂肪,促进吸收。
S5820 L-Hydroxyproline L-Hydroxyproline (trans-4-Hydroxy-L-proline)是一种胶原特异的氨基酸。它被用作骨转换和肝纤维化的诊断标记物。
S5824 Cinnamyl alcohol Cinnamyl alcohol是一种存在于肉桂中的天然产物。
S5821 Linoleic acid Linoleic acid (9,12-octadecadienoic acid)是一种必需脂肪酸,用于合成花生四烯酸,存在于细胞膜脂质中。
S5823 L-Pyroglutamic acid L-pyroglutamic acid (L-pyroglutamate, 5-Oxoproline, pidolic acid)是一种天然营养物,是来源于谷氨酸的氨基酸。它是谷胱甘肽循环的代谢物,能通过5-羟脯氨酸酶转化为谷氨酸。
S5828 L-Abrine L-Abrine (N-Methyl-L-tryptophan)是相思子根部的毒性清蛋白,可抑制核糖体。
S9367 Adenosine disodium triphosphate hydrate Adenosine disodium triphosphate hydrate (ATP disodium) is the sodium salt form of adenosine triphosphate (ATP), a complex organic chemical that provides energy to drive many processes in living cells.
S5805 Allopregnanolone Allopregnanolone是一种神经类固醇,在脑内由黄体酮合成而来,是高效的GABAA receptor正向别构调节剂。
S5771 Sulforaphane Sulforaphane 是一种天然存在的异硫氰酸盐,存在于十字花科蔬菜如西兰花、卷心菜、羽衣甘蓝。它是 Nrf2 的诱导物。Sulforaphane 也是 histone deacetylase (HDAC)NF-κB 的抑制剂。Sulforaphane 可增加 heme oxygenase-1 (HO-1),并降低 reactive oxygen species (ROS) 的水平。Sulforaphane 诱导细胞周期停滞和凋亡。
S9334 2-Pentylfuran 2-Pentylfuran (2-Amylfuran)是天然存在的香料成分。
S9383 Methyl palmitate Methyl palmitate (Methyl hexadecanoate, Palmitic acid methyl ester), a kind of fatty acid methyl ester, could be found in many plants and possesses acaricidal activity.
S9453 2-Undecanol 2-Undecanol (Methyl nonyl carbinol, 2-Hydroxyundecane, 2-Hendecanol) is a fatty alcohol lipid molecule.
S9454 Undecanoic acid Undecanoic acid (Undecylic acid) is a medium chain length monocarboxylic acid that appears to be involved in the control of triacylglycerol synthesis.
S9385 Ligustilide Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. 在溶液中不稳定,请现配现用!
S9033 Incensole acetate Incensole acetate, isolated from Boswellia Resin, is a novel anti-inflammatory compound that inhibits NF-κB activation.
S9043 6-Shogaol 6-Shogaol, a naturally occuring product found in ginger, has anti-inflammatory and anticancer properties.
S9071 Nootkatone Nootkatone, a natural ingredient that occurs in grapefruit and certain other plants, has antioxidant and anti-inflammatory effects.
S9094 Pogostone Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.
S9118 Beta-Asarone Beta-Asarone, found in certain plants such as Acorus and Asarum, could pass the blood-brain barrier and exerts neuroprotection effects.
S9140 Pulegone Pulegone, a naturally occurring organic compound, is a fragrance and flavour ingredient.
S9142 Sparteine Sparteine, which could be extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent.
S9236 α-Cyperone α-Cyperone (alpha-cyperone) 是香附子Cyperus rotundus的主要活性成分,表现出了如抗毒力、抗原毒性和抗菌活性等生物活性。α-Cyperone (alpha-cyperone) 与COX-2IL-6Nck-2Cdc42Rac1 的表达下调有关。
S9263 3-n-Butylphathlide 3-n-Butylphathlide, initially isolated from the seeds of Apium graveolens Linn., has shown significant neuroprotective effects.
S5370 10-Hydroxydecanoic acid 10-Hydroxydecanoic acid, a minor constituent of royal jelly, is a saturated fatty acid that has cytotoxic effects.
S9450 1-Undecanol 1-Undecanol (Undecyl alcohol, 1-Hendecanol), found naturally in many foods such as fruits (including apples and bananas), butter, eggs and cooked pork, is used as a flavoring ingredient.
S5761 Citric acid Citric acid is a weak organic acid that occurs naturally in citrus fruits. It is an intermediate in the citric acid cycle.
S5763 D-Mannose D-mannose is a naturally occurring simple sugar that may help your body cleanse the urinary tract and maintain a healthy bladder lining.
S5391 α-Boswellic acid α-Boswellic acid is a naturally occuring triterpenoic acid.
S5757 Isoeugenol Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
S5759 Methyl linoleate Methyl linoleate (Linoleic acid methyl ester), found in cloves, is a fatty acid methyl ester of linoleic acid which is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes.
S5756 Methyl Stearate Methyl Stearate (Methyl Octadecanoate, Stearic Acid methyl ester), found in cloves, is an antifoaming agent and fermentation nutrient.
S5577 6-Biopterin 6-Biopterin ( L-Biopterin, L-Erythro-Biopterin) is a natural product that has been considered as a growth factor for some insects.
S5743 γ-Linolenic acid γ-Linolenic Acid (18:3, n-6), the Δ6-desaturase product of linolenic acid, is an unsaturated fatty acid found primarily in vegetable oils.
S5600 Flavokawain A Flavokawain A 是一种从 kava 提取的凋亡诱导剂和抗癌剂。 Flavokawain A 可以下调抗凋亡蛋白,例如 XIAP、 survivin 和 Bcl-xL,从而改变凋亡与抗凋亡分子之间的平衡、诱导肿瘤细胞死亡。
S5732 Sebacic acid Sebacic acid (1,8-Octanedicarboxylic acid) is a saturated, straight-chain naturally occurring dicarboxylic acid
S5733 Stearic acid Stearic acid (Octadecanoic acid, Isostearic acid, Cetylacetic acid) is a natural saturated fatty acid found in animal and vegetable fats. It could be used as a food additive and used in soaps, cosmetics and detergents.
S9375 2'-Hydroxyacetophenone 2'-Hydroxyacetophenone is a flavouring ingredient.
S9379 Dihydrocoumarin Dihydrocoumarin, a compound found in Melilotus officinalis (sweet clover) and Dipteryx odorata Willd (tonka beans), is added as a flavoring agent to a wide variety of foods, including soft drinks, yogurt, and muffins, and is used as a common fragrance in cosmetics, lotions, and soaps.
S9382 Thymine Thymine (5-methyluracil) is one of the four nucleobases in the nucleic acid of DNA.
S9333 Gibberellins A4/A7 Gibberellins A4/A7是赤霉素A4与赤霉素A7的混合物。赤霉素A4/A7促进种子节间伸长和打破某些休眠。赤霉素A4/A7是一种内源植物生长调节剂,促进细胞生长和伸长。
S5691 Terpinyl Acetate Terpinyl Acetate (alpha-Terpinyl), a naturally occuring compound found in several essential oils, is a flavouring agent.
S5616 4-Methylcatechol 4-Methylcatechol (P-Methylcatechol, 3,4-Dihydroxytoluene, Homocatechol) is an inducer of nerve growth factor. It is used to synthesize antimicrobial and antioxidant.
S5684 Lapachol Lapachol (Tecomin, CI75490, Bethabarra wood, Greenhartin), a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.
S5640 Ethyl caffeate Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
S5680 (-)-Verbenone (-)-Verbenone (2-Pinen-4-one), an important component of the essential oil from rosemary, is an insect pheromone with a spicy odor and camphoraceous fragrance.
S5617 Myristic Acid Myristic acid (Tetradecanoic acid) is a fatty acid that occurs naturally in some foods. Myristic acid inhibits the phosphorylation of poly E4Y by Src with an Ki of 35 μM.
S9046 Berberine Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.
S9047 Leonurine Hydrochloride Leonurine (SCM-198), a natural alkaloid extracted from Herba leonuri, is a promising anti-glycation agent with vasodilator, antioxidative, cardioprotective and neuroprotective effects.
S9037 Tenacissoside H Tenacissoside H, a natural compound found in M. tenacissima, exerts anti-inflammatory and anti-tumor effects.
S9027 Corynoxine Corynoxine, a natural oxindole alkaloid, is a new autophagy enhancer.
S9041 Corosolic acid Corosolic acid (Glucosol, Colosic acid, 2α-Hydroxyursolic acid) is one of the pentacyclic triterpenoids isolated from Lagerstroemia speciose and has been reported to exhibit anti-cancer and anti-proliferative activities in various cancer cells.
S9035 Isovitexin Isovitexin (saponaretin, Apigenin-6-C-glucoside), an active component of many traditional Chinese medicines, has various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.
S9032 Sanguinarine Sanguinarine (Pseudochelerythrine, Sanguinarin, Sanguinarium), a benzophenanthridine alkaloid known as an anti-inflammatory agent, is a potent inhibitor of NF-κB activation.
S9036 (20R)Ginsenoside Rh2 (20R)Ginsenoside Rh2, a natural compound found in Panax ginseng, shows antiviral and anticancer activities. It is a matrix metalloproteinase (MMP) inhibitor.
S9024 AKBA (3-O-Acetyl-11-keto-β-boswellic acid) AKBA (3-O-Acetyl-11-keto-β-boswellic acid), the major active ingredient of the gum resin from Boswellia serrata and Boswellia carteri Birdw., exerts anti-inflammatory therapeutic effects and noncompetitively inhibits 5-lipoxygenase, topoisomerase, and leukocyte elastase.
S9044 Ginsenoside F2 Ginsenoside F2, a ginsenoside found in Panax species, is an autophagic initiater with anti-cancer, and anti-obesity activities.
S9042 Wedelolactone Wedelolactone, a medicinal plant-derived natural compound, is an inhibitor of IKK that is critical for activation of NF-κB by mediating phosphorylation and degradation of IκBα. Wedelolactone is also an inhibitor of caspase-11.
S9030 Tenacissoside I Tenacissoside I is a natural compound found in M. tenacissima at relatively high level.
S5677 Xanthopterin Hydrate Xanthopterin, isolated from butterfly wings and found in many other sources, replace folic acid in the nutrition of many animal species.
S9353 L-serine L-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
S9349 D-(+)-Raffinose pentahydrate Raffinose is a trisaccharide composed of galactose, glucose, and fructose.
S9341 3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S9344 DL-Methionine DL-Methionine is an amino acid that has a role in the defence of oxidative stress.
S9004 Chondroitin 4-sulfate Chondroitin 4-sulfate is an important structural component of cartilage and has been used as a dietary supplement to treat symptoms of joint discomfort.
S9373 Neryl acetate Neryl acetate (Nerol, Acetic acid neryl ester, cis-Geranyl), a chemical compound found in citrus oils, is a flavouring agent.
S9339 S-(-)-Cotinine S-(-)-Cotinine, a constituent of tobacco products and the major metabolite of nicotine, stimulates nicotinic receptors to evoke the release of DA in a calcium-dependent manner from superfused rat striatal slices.
S9372 Ethyl palmitate Ethyl palmitate (Ethyl hexadecanoate, Palmitic acid ethyl ester) is a long-chain fatty acid ethyl ester that is used as a hair- and skin-conditioning agent.
S4937 4'-Hydroxychalcone 4'-Hydroxychalcone (P-Cinnamoylphenol),存在于草药、香料和茶叶中,是一种刺甘草查尔酮。它具有多种生物活性,能够抑制TNF-α诱导的NF-κB通路激活、并激活BMP信号通路。
S3622 Diammonium Glycyrrhizinate Diammonium glycyrrhizinate (DG)是一种传统的中草药,从甘草中提取纯化而来。它具有抗炎活性,对生物氧化具有抗性、对膜具有保护性。DG通过抑制NF-κB、TNF-α和细胞间黏附分子1来减少炎症损伤。
S3769 Palmatine Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.
S3788 Carvacrol Carvacrol (Cymophenol), monoterpenic phenol isomeric with thymol, has diverse activities such as antimicrobial, antitumor, an-timutagenic, antigenotoxic, analgesic, antispasmodic, anti-inflammatory, angiogenic, antiparasitic, antiplatelet, AChE inhibitory, antielastase, insecticidal, antihepatotoxic and hepatoprotective activities.
S5176 Fructose Fructose (D-(-)-Fructose, Fruit sugar, levulose, fructosteril, D-fructofuranose, D-arabino-hexulose) is a simple ketonic monosaccharide found in many plants.
S5178 4-Hydroxy-2,5-dimethyl-3(2H)furanone 4-Hydroxy-2,5-dimethyl-3(2H)furanone (furaneol, HDMF) is a naturally occurring substance found in a variety of fruits and has been shown to have antimicrobial activity.
S5592 Vitamin A (Retinol) Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs.
S5591 Ectoine Ectoine ( THP(B)) is a natural amino acid derivate with membrane stabilizing and inflammation reducing capacities. It is produced by bacteria living under extreme harsh environmental conditions where it serves as osmoregulatory compatible solute.
S4888 Guanine Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA.
S5505 2’-deoxyuridine 2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.
S5503 O-Acetyl-L-carnitine hydrochloride O-Acetyl-L-carnitine (Acetyl-L-carnitine, O-acetyl-L-carnitine, O-Acetylcarnitine) can be synthesis or is naturally found in healthy humans. It could help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs.
S9368 ADP ADP (Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate) is an important organic compound in metabolism and is essential to the flow of energy in living cells.
S5550 Ethyl gallate Ethyl gallat (Phyllemblin, gallic acid ethyl ester), which could be found naturally in a variety of plant sources, is a food additive with antimicrobial activity.
S9390 Astragaloside II Astragaloside II, extracted from Astragalus membranaceus, has been reported to promote tissue wound repair and could be a potential adjunctive agent in cancer chemotherapy, enhancement of osteogenesis, and modulation of T cell activation.
S9166 Griffonilide Griffonilide is a natural product that has been reported to induce bone remodeling activity resulting in structural changes.
S9169 Polygalasaponin F
S9198 Obtusifolin Obtusifolin is anthraquinone found in the seeds of Cassia obtusifolia, has inhibitory effects on platelet aggregation and aldose reductase.
S9220 Stylopine hydrochloride Stylopine (Tetrahydrocoptisine, Coptisine), a major component of the leaf of Chelidonium majus L., is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.
S9241 Polygalaxanthone III Polygalaxanthone III 是一种天然产物,具有镇静,减轻感冒,消除痰液和消肿的功效。Polygalaxanthone III 抑制 CYP2E1 催化的氯唑沙宗6-羟基化反应,IC50值为50.56 μM。
S9259 Lithospermic acid Lithospermic acid, an active component isolated from Salvia miltiorrhiza radix, is known to have multiple pharmacological actions such as antihypertensive and antioxidant effects.
S9262 Raddeanin A Raddeanin A (Raddeanin R3, NSC382873), a triterpenoid saponin from Anemone raddeana Regel, displays moderate inhibitory activity against histone deacetylases (HDACs) and has high antiangiogenic potency, antitumor activity.
S9264 Decursin Decursin is a pyranocoumarin obtained from the roots of Angelica gigas Nakai that exhibits anti-cancer, anti-inflammatory and neuroprotective activities.
S9306 Corynoxeine Corynoxeine, which could be isolated from Uncaria rhynchophylla, is a useful and prospective compound in the prevention and treatment for vascular diseases. It is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation.
S9310 Isorhychophylline Isorhynchophylline (IsoRhy, 7-Isorhyncophylline) is a major tetracyclic oxindole alkaloid isolated from the Chinese herbal medicine Uncaria rhynchophylla (Miq.)Jacks (Gouteng in Chinese). It acts as a neuronal autophagy inducer with therapeutic potential for cardiovascular and central nervous system diseases.
S9414 Cyasterone Cyasterone is the main phytoecdysteroid component found in Cyathula capitata. It is a natural EGFR inhibitor and maybe a promising anti-cancer agent.
S9448 D-(+)-Turanose D(+)-Turanose is a naturally occuring compound. It is a reducing disaccharide.
S5745 Glyceryl 1,3-dipalmitate Glyceryl 1,3-dipalmitate acts as a metabolite of saccharomyces cerevisiae, plant and human.
S9507 (−)-Norepinephrine (−)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline)是一种天然存在的神经递质和激素。它是adrenergic receptors的激动剂,对α1, α2A和β1肾上腺素受体的Ki值分别为330 nM、56 nM和740 nM。
S9505 Oleanonic Acid Oleanonic Acid (3-Ketooleanolic Acid, 3-Oxooleanolic acid), extracted from Pistacia terebinthus galls, is a cell cycle inhibitor and used as antitumor agents.
S5686 Tryptanthrin Tryptanthrin is a natural alkaloidal compound having basic indoloquinazoline moiety. It has broad spectrum of biological activities including anticancer activity, anti-inflammatory, antiprotozoal, antiallergic, antioxidant, and antimicrobial.
S5690 Triacanthine Triacanthine, which could be isolated from the leaves of G. triacanthos, shows hypertensive activity, also cardiotonic, antispasmodic and a respiratory analeptic.
S5554 Lanatoside C Lanatoside C 是具有抗病毒和抗肿瘤活性的强心苷。Lanatoside C 通过减弱 MAPK,Wnt,JAK-STAT和PI3K/AKT/mTOR信号通路,诱导G2/M细胞周期停滞并诱导自噬和细胞凋亡。
S5312 Urolithin A Urolithin A (3,8-Dihydroxy Urolithin, 2',7-Dihydroxy-3,4-benzocoumarin), 是鞣花酸的代谢产物,是一种首创的天然化合物,口服后可在体外和体内诱导线粒体自噬。
S3817 Harmine hydrochloride Harmine (Telepathine)是属于β-咔啉家族化合物的一种荧光harmala生物碱,是一种高细胞渗透性的 DYRK1A 的激酶口袋结合ATP的竞争性抑制剂,与DYRK2结合IC50值高约60倍。Harmine 还可以抑制 monoamine oxidases (MAOs), PPARγcdc-like kinases (CLKs)。Harmine 抑制 5-HT2A serotonin receptor 的Ki值为397 nM。
S5318 Acacetin Acacetin (Linarigenin, 5,7-dihydroxy-4'-methoxyflavone, 4'-Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects.
S9345 Disodium 5'-Inosinate Disodium 5'-Inosinate, widely distributed in all animal and plant tissues, is used as a flavor enhancer.
S9059 4'-O-Glucosylvitexin 4'-O-Glucosylvitexin is a kind of flavonoid fraction from the leaves of Crataegus pinnatifida.
S9364 6-Hydroxycoumarin 6-Hydroxycoumarin demonstrates cytotoxic effect against the cancer cell lines.
S9365 Disodium uridine-5'-monophosphate Disodium uridine-5'-monophosphate is a nucleotide that is a major component of ribonucleic acid.
S9366 5'-Adenylic acid AMP, also known as 5'-Adenylic acid and Adenosine monophosphate, is a nucleotide that is found in RNA. It is used as a dietary supplement to boost immune activity, and is also used as a substitute sweetener to aid in the maintenance of a low-calorie diet.
S9369 Xanthosine Xanthosine (Xanthine riboside) is an intermediate in purine metabolism, formed from IMP, and forming GMP.
S9370 Adenosine Cyclophosphate Adenosine Cyclophosphate (Cyclic adenosine monophosphate, cAMP, cyclic AMP, 3',5'-cyclic adenosine monophosphate) is useful for improving myocardial hypoxia, dilating coronary artery and strengthening myocardiac contraction.
S9384 Sophocarpine Monohydrate Sophocarpine, a naturally occurring tetracyclic quinolizidine alkaloid derived from Sophora alopecuroides L, has shown promising therapeutic properties, including anti-inflammatory, anti-nociceptive, and antivirus activities.
S9386 Polygalacic acid Polygalacic acid 是从远志属植物(Polygala paenea L.)分离出的三萜类四羟酸。Polygalacic acid (0-100μM; 24h) 可以显著降低 MMP-3、MMP-9、MMP-13 和 COX-2 的mRNA表达,这些因子的表达由IL-1β诱导可显著增加,并呈现出剂量依赖性。
S9387 Maackiain Maackiain (Demethylpterocarpin) is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects.
S9388 (+)-Praeruptorin A Praeruptorin A is a coumarin compound naturally occurring in the roots of Peucedanum praeruptorum Dunn., a commonly used traditional Chinese medicine for the treatment of certain respiratory diseases and hypertension. Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation. (+)-Praeruptorin A is one of enantiomers.
S9389 Phorbol Phorbol is a natural, plant-derived organic compound that exerts a broad range of biological activities.
S9401 3,6'-Disinapoyl sucrose 3,6'-Disinapoyl sucrose (Disinapoyl sucrose), an oligosaccharide ester natural product originating from the root of wild Polygala tenuifolia, has neuroprotective effects and antidepressive activity in rats.
S9400 Rhynchophylline Rhynchophylline (Mitrinermine), an active component isolated from species of the genus Uncaria, acts as a calcium channel blocker and is widely used in traditional Chinese medicine mainly for treating ailments of central nervous and cardiovascular systems, such as lightheadedness, convulsions, numbness, and hypertension.
S9398 Crassicauline A Crassicauline A, a diterpenoid alkaloid in Aconitum herbs, is an analgesic drug clinically used in China.
S9397 Alliin Alliin (S-allyl cysteine sulfoxide, ACSO, 3-(Allylsulphinyl)-L-alanine) is a sulfoxide that is a natural constituent of fresh garlic.
S9396 Geraniin Geraniin, a hydrolysable polyphenol derived from Nephelium lappaceum L. fruit rind, has been shown to possess significant antioxidant activity in vitro.
S9392 Praeruptorin B Praeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities.
S9402 (20R)-Protopanaxadiol (20R)-Protopanaxadiol, isolated from the roots of Panax ginseng, has protective effect on myocardial ischemia.
S9404 Pristimerin Pristimerin is a naturally occurring triterpenoid that has been shown to suppress the proliferation of various cancer cell lines at the concentration (IC50) range of 0.2-4 μM, including those of breast, glioma, prostate, pancreatic, ovarian, colon.
S9405 Sesamoside Sesamoside, a main chemical ingredient iridoid glycoside from Lamiophlomic rotata, has analgesic and anti-inflammatory effects in animal studies.
S9406 Sauchinone Sauchinone, one of the active lignan isolated from the roots of Saururus chinensis, possesses diverse pharmacological properties, such as hepatoprotective, anti-inflammatory and anti-tumor effects.
S9407 Angoroside C Angoroside C, an important phenylpropanoid glycoside of the traditional Chinese medicine Scrophulariae Radix, possesses the effects of preventing ventricular remodeling, reducing pulmonary oedema, and reducing blood pressure, as well as having the properties of anti-platelet aggregation, hepatoprotection and anti-nephritis, etc.
S9408 Beta-Elemonic acid Beta-Elemonic acid (3-Oxotirucallenoic Acid), a known triterpene isolated from Boswellia (Burseraceae), exhibits anti‑inflammatory effects.
S9409 Kavain Kavain, the main kavalactone found mostly in the roots of the kava plant, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels.
S9410 Euphorbia factor L1 Euphorbia factor L1, a diterpenoid isolated from Euphorbia lathyris, inhibits osteoclastogenesis and induces osteoclast apoptosis.
S9411 Liensinine Liensinine, an important functional compound in lotus seeds, has anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities.
S9412 Flavokawain B Flavokawain B is a natural chalcone first isolated from extracts of kava roots that induces apoptosis in cancer cells.
S9413 Yangonin Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
S9416 Triptonide Triptonide, isolated from the roots of Tripterygium wilfordii, can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin. It is also an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent.
S9417 Homoplantaginin Homoplantaginin (Hispidulin-7-glucoside) 是中草药丹参中的主要类黄酮,具有抗炎和抗氧化作用。Homoplantaginin 可抑制 TNF-αIL-6 mRNA 表达,IKKβNF-κB 磷酸化。
S9420 Sinoacutine Sinoacutine (Salutaridine), isolated from the Chinese drug Ching-fengteng, elicits mild antitussive properties.
S9421 Demethylnobiletin Demethylnobiletin (5-Demethylnobiletin)是一种在柑橘类水果中发现的独特的类黄酮,具有潜在的化学预防人类癌症的作用。5-Demethylnobiletinin 是 5-LOX 的直接抑制剂,IC50值为0.1 μM,且不影响COX-2的表达。5-Demethylnobiletinin 具有抗炎活性,可抑制大鼠中性粒细胞中 leukotriene B 4(LTB4) 的形成和人中性粒细胞中elastase弹性蛋白酶 (elastase) 的释放,IC50为0.35 μM。
S9422 Diosbulbin B Diosbulbin B is the main hepatotoxic compound in Airpotato yam, which is traditionally used for treating thyroid disease and cancer.
S9423 Narcissoside
S9425 Trifolirhizin Trifolirhizin, a natural pterocarcan flavonoid extracted from Sophora flavescens, has many pharmacological activities, such as hepatoprotective, anti-inflammatory, anti-proliferation, and skin-whitening.
S9427 Tabersonine Tabersonine is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus and shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity.
S9428 Brazilin Brazilin (Natural Red 24) is a red pigment obtained from the wood of the brazilwood family. It is used to dye fabric and has diverse biological activities, including neuroprotective, anti-inflammatory, antibacterial, and antioxidant properties.
S9429 6α-Hydroxygeniposide 6α-Hydroxygeniposide, an iridoid glycoside, is a chemical constituents of Pittosporum glabratum Lindl.
S9430 Tomatidine Hydrochloride Tomatidine Hydrochloride, a natural steroidal alkaloid, possesses potent antibacterial activity and has anti-inflammatory effects in macrophages.
S9431 Dehydrocorydalin Dehydrocorydalin is an alkaloidal component isolated from Rhizoma corydalis. It has anti-inflammatory and anti-tumor effects and can protect the cardiovascular system.
S9433 Tubeimoside II Tubeimoside II (Tubeimoside B), a natural triterpenoid saponin isolated from herb, show anti-inflammatory, antitumor, and antitumor-promoting effects.
S9434 8-Gingerol 8-Gingerol is a bioactive ingredient of ginger root (Zingiber officinale), a medicinal plant having anti-nausea, anti-inflammatory, and anti-carcinogenic properties and a carminative effect.
S9435 Secoxyloganin Secoxyloganin is a secoiridoids that is extensively used in synthetic and biosynthetic studies of monoterpene indole alkaloids and related natural products.
S9436 Pinoresinol dimethyl ether Pinoresinol dimethyl ether, which could be isolated from the wood of the basal tree Humbertieae, show a variety of activities as the inhibitor of cyclic AMP phosphodiesterase.
S9437 Echinatin Echinatin is a licorice extract that displays antioxidant properties and anti-inflammatory activities.
S9438 Isosakuranetin Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found in Citrus species.
S9120 Scutellarein Scutellarein (6-Hydroxyapigenin), extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities.
S9439 Kaurenoic acid Kaurenoic acid (kaurenoate, kaur-16-en-18-oic acid) is a natural diterpenoid found in the herbs of Croton antisyphiliticus. Kaurenoic acid has anti-inflammatory activity, the mechanisms may through inhibition of iNOS and COX-2 expression.
S9441 Sibiricose A5 Sibiricose A5, which could be isolated from traditional Chinese medicine Polygalae Radix, shows potent antioxidant activity.
S9442 Bergaptol Bergaptol (5-Hydroxypsoralen, 5-Hydroxyfuranocoumarin)是在柠檬、佛手柑等柑橘精油中发现的天然呋喃香豆素。Bergaptol 是有效的 CYP3A4 酶脱苄基活性抑制剂,IC50值为24.92 μM。
S9443 Schisantherin B Schisantherin B is one bioactive of lignans isolated from Schisandra chinensis (Turcz.) Baill which has been commonly used as a traditional herbal medicine.
S9444 Tomatine Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S9446 Dihydrokavain Dihydrokavain (Marindinin) is a kavalactone source from kava beverages used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
S9447 1F-Fructofuranosylnystose 1F-Fructofuranosylnystose is a kind of Fructooligosaccharides which are naturally occurring sugars with potentially beneficial nutritional effects.
S9503 Fraxetin Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.
S9502 Madecassic acid Madecassic acid (Brahmic acid) 是最早从积雪草中分离的天然三萜,具有多种消炎和抗糖尿病作用,阻断巨噬细胞中的 NF-κB 活化并导致 iNOSCOX-2TNF-alphaIL-1betaIL-6 抑制。
S9001 Malic acid Malic acid (Hydroxybutanedioic acid, 2-Hydroxysuccinic acid) is a common, naturally occurring ingredient in many foods. It is the main acid found in apples and other fruits.
S9002 L-Fucose Fucose (6-Deoxy-L-Galactose, L-fucopyranose) is found on N-linked glycans on the mammalian, insect and plant cell surface. L-Fucose is claimed to have application in cosmetics, pharmaceuticals, and dietary supplements.
S9006 Perillartine Perillartine (Perilla sugar, Peryllartine) is a sweetener.
S9014 AstragalosideⅠ AstragalosideⅠ, is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.
S5083 Lentinan Lentinan (A823605, Bromoduline),分离纯化自香菇子实体水煮提取物,是一种真菌多糖免疫调制剂,具有抗肿瘤活性。
S9272 Koumine Koumine, a Gelsemium alkaloid, possesses analgesic, anti-inflammatory and neurosteroid modulating activities.
S9273 Timosaponin BII Timosaponin BII (BII, Prototimosaponin AIII) is a steroidal saponin showing potential anti-dementia and antioxidant activity.
S9274 Isochlorogenic acid B Isochlorogenic acid B, naturally isolated from Laggera alata, has antioxidative and hepatoprotective properties.
S9275 Isoguanosine Isoguanosine (Crotonoside)抑制 FLT3 和 HDAC3/6 治疗AML。Isoguanosine 是巴豆(Croton tiglium)种子中天然存在的鸟苷的活性异构体。
S9276 Alisol B Alisol B, a triterpene from Alismatis rhizoma, induces Bax up-regulation and nuclear translocation, the activation of initiator caspase-8 and caspase-9, and executor caspase-3, suggesting the involvement of both extrinsic and intrinsic apoptosis pathways.
S9277 Alisol A Alisol A is one of the major active triterpenes isolated from Rhizoma Alismatis (RA), a famous Traditional Chinese Medicine widely used for diuretic, hypolipidemic, anti-nephrolithic, anti-atherosclerotic, anti-inflammatory and anti-diabetic purposes.
S9278 Saikosaponin C Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities.
S9279 Euphorbia factor L3 Euphorbia factor L3 (5,15-Diacetyl-3-benzoyllathyrol), belonging to the lathyrane diterpenoids isolated from Caper Euphorbia Seed, shows potent cytotoxicity and induces apoptosis via the mitochondrial pathway in A549 cells.
S9280 Demethoxycurcumin Demethoxycurcumin, a natural demethoxy derivative of curcumin, has anti-oxidant, anti-inflammatory, anti-cancer, and anti-angiogenesis properties.
S9281 Peimine Peimine (Verticine, Wanpeinine A) is a major biologically active component of Fritillaria ussuriensis, exhibits anti-inflammatory and pain suppression properties at the cellular level.
S9267 Epimedin A Epimedin A is a major component of Herba Epimedii with bioactivities.
S9268 Epmedin B Epmedin B (Epimedin B) is a component extracted from Epimedii Folium and may have antiosteoporotic activity.
S9269 Epmedin C Epmedin C (Epimedin C, Baohuoside VI), a flavonoid isolated from the herbs of Epimedium brevicornum Maxim, exhibits immunostimulatory and anticancer activities.
S9270 Dracohodin perochlorate Dracohodin perochlorate, extracted from Dragon's blood, is widely used in traditional Chinese medicine, especially in wound healing.
S9271 Pulchinenoside A Pulchinenoside A (Anemoside A3), a natural triterpenoid saponin, is a AMPARs and NMDAR modulator.
S9282 Isochlorogenic acid A Isochlorogenic acid A (3,5-dicaffeoylquinic acid), isolated from Brazilian propolis and Suaeda glauca, exhibits hepatoprotective and cytotoxic activities.
S9283 Aristolone Aristolone, which could be extracted from essential oil of Elyonurus hensii, is likely to induce an antalgic activity.
S9284 Aloesin Aloesin (Aloe resin B) is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro.
S9285 Fargesin Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.
S9286 Neobavaisoflavone Neobavaisoflavone, isolated from seeds of Psoralea corylifolia, exhibits inhibitory activity against DNA polymerase and platelet aggregation.
S9287 Genkwanin Genkwanin (Apigenin 7-methyl ether) is one of the major non-glycosylated flavonoids in herbs. It has a variety of pharmacological effects including anti-inflammatory, anti-bacterial, antiplasmodial, radical scavenging, chemopreventive and inhibiting 17β-Hydroxysteroid dehydrogenase type 1 activities.
S9288 Casticin Casticin (Vitexicarpin), as the major active substance in Lithospermum erythrorhyzon, had been reported to mediate multiple pharmacological activities such as antioxidation, antiviral, cardiovascular protection, antineoplastic and anti-inflammation.
S9289 Astragalin Astragalin (kaempferol-3-glucoside, Kaempferol 3-O-glucoside, Kaempferol 3-D-glucoside), a flavonoid from leaves of persimmon and green tea seeds, has anti-tumor, anti-inflammatory and anti-oxidant activities.
S9290 Linarin Linarin (Acaciin, Buddleoside, Acacetin-7-O-rutinoside), a natural flavonoid cpompound, has pharmacological effects, including anti-inflammatory, neuro-protective, cardioprotective and antioxidative effects.
S9291 Isopimpinellin Isopimpinellin (5,8-Dimethoxypsoralen) is a natural product synthesized by numerous plant species. It may acts as an anticarcinogen.
S9292 Dictamnine Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
S9293 Isoliquiritin Isoliquiritin (Neoisoliquritin) is a flavonoid glycoside compound from licorice possessing a broad spectrum of pharmacological activities including antioxidant, anti-inflammatory, and anti-depression activities.
S9294 Gelsemine Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., is a highly toxic compound and may be a glycine receptor agonist with significantly higher binding affinity for some of these receptors than its native agonist, glycine.
S9295 Dauricine Dauricine, a plant metabolite isolated from the Asian vine Menispermum dauricum, plays a variety of biological roles in the human body, from inhibiting cancer cell growth to blocking cardiac transmembrane Na+, K+, and Ca2+ ion currents.Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF‐κB signaling pathway in colon cancer cells.
S9296 Fraxin Fraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis.
S9297 Kirenol Kirenol is a biologically active substance isolated from Herba Siegesbeckiae. It has been reported to possess anti-oxidant, anti-inflammatory, anti-allergic, anti-adipogenic, and anti-arthritic activities.
S9298 Corylin Corylin, a main compound isolated from Psoralea corylifolia L. (Fabaceae), has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties.
S9300 Methylprotodioscin Methyl protodioscin, a bioactive natural compound isolated from Dioscorea collettii Makino (Dioscoreaceae), has numerous pharmacological activities, including anti-inflammation, lipid-lowering, and anticancer activities.
S9301 Verbenalin Verbenalin (Verbenalol β-D-glucopyranoside, Verbenalol glucoside, Cornin), an iridoid glycoside found in Verbena officinalis, has been reported to exhibit uterine stimulant activity and demonstrated cardioprotection against experimental myocardial ischemic injury.
S9302 Polyphyllin VI Polyphyllin VI derived from Paris polyphylla possess anti-cancer activities.
S9303 Saikosaponin B2 Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.
S9304 Platycodin D Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anti-inflammatory, anti-allergic, cholesterol-lowering and neuroprotective properties.
S9305 Toosendanin Toosendanin, a triterpenoid extracted from Melia toosendan Sieb et Zucc, possesses broad biological actions from blocking neurotransmission and antibotulism to inducing cell differentiation and apoptosis.
S9307 Shanzhiside methyl ester Shanzhiside methylester is a principle effective iridoid glycoside of L. rotata and serves as a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist.
S9308 Pulsatilla saponin D Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla koreana, targets c-Met and exerts antiangiogenic and antitumor activities.
S9309 Micheliolide Micheliolide, a sesquiterpene lactone isolated from Michelia compressa and Michelia champaca, inhibits various inflammatory response and may serve as a neuroprotective agent in neuroinflammation-related neurodegenerative disorders.
S9311 Germacrone Germacrone, a major activity component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antimicrobial activities.
S9312 Cyanidin-3-O-glucoside chloride Cyanidin-3-O-glucoside chloride (Kuromanin, Chrysontemin, Glucocyanidin) is a natural product with anti-oxidant and neuroprotective effects.
S9313 Atractylenolide III Atractylenolide III, a major component of Atractylodes rhizome, has anti-inflammatory and anti-angiogenesis activities.
S9314 Atractylenolide II Atractylenolide II (AT-II, Asterolide, 2-Atractylenolide), a major sesquiterpenoids isolated from the dried Rhizome of Atractylodes macrocephala, shows a wide range of biological and pharmacological activities, for example, against insomnia and anxiety, neuroprotective, platelet activation and anti-cancer effect.
S9315 Praeruptorin A Praeruptorin A, a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. Praeruptorin A inhibits p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation. Praeruptorin A can significantly upregulates multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction.
S9316 Polyphyllin II Polyphyllin II, a natural compound extracted from Rhizoma of Paris polyphyllin, shows hemolytic activity.
S9317 Forsythoside A Forsythoside A, one of the main active ingredients in Forsythiae fructus, has been shown to possess anti-bacterial and immunomodulatory properties.
S9318 (20R)-Ginsenoside Rh1 (20R)-Ginsenoside Rh1, isolated from the root of Panax Ginseng, exhibits various pharmacological activities including vasorelaxation, antioxidation, anti-inflammation, and anticancer.
S9319 Cryptochlorogenic acid Cryptochlorogenic acid (4-Caffeoylquinic acid, 4-O-Caffeoylquinic acid), a phenolic acid found in various plant species, including Artemisia, honeysuckle, and H. sabdariffa, possesses antioxidant properties.
S9322 Neodiosmin Neodiosmin (Diosmetin-7-neohesperidoside, Diosmetin-7-O-neohesperidoside), a flavone glycoside isolated from C. aurantium, is a strong antioxidant with potential applications in foods, beverages, and pharmaceutical preparations.
S9324 Alnustone Alnustone, a naturally occuring compound found in the rhizomes of Curcuma xanthorrhiza, exhibits anti-inflammatory, antihepatotoxic and antiemetic activities.
S9329 Orcinol Orcinol (5-Methylresorcinol; 3,5-ToluenediolOrcin; 5-Methyl-1,3-benzenediol; 3,5-Dihydroxytoluene), occurs in many species of lichens including Roccella tinctoria and Lecanora, exhibits antimutagenic, antioxidant, antibacterial, radical-scavenging effects.
S9343 Sequoyitol Sequoia alcohol (Sequoyitol) is isolated from Taxus natural organic compounds, it can be used to treat diabetes and other indications.
S9347 Allitol Allitol (Allodulcitol) is a rare polyol found in nature that is useful not only as a sweetener, but also as the raw material for production of chemical compounds.
S9348 D-(+)-Trehalose Anhydrous Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.
S9350 Ethyl 4-Methoxycinnamate Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S9354 Oxalic acid Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.
S5636 Methyl furan-2-carboxylate Methyl furan-2-carboxylate (Methyl pyromucate, Methyl 2-furoate) is found in cocoa and cocoa products. It is used in food flavouring and preparation of sesquiterpene lactone.
S3814 Tubeimoside I Tubeimoside I (Lobatoside H, TBMS1), a triterpenoid saponin, isolated from the tubers of Bolbostemma paniculatum, shows potent antitumor and antitumor-promoting effects.
S8068 Chaetocin Chaetocin,一类来自毛壳菌属的天然产物,是一类 histone methyltransferase 抑制剂,其对dSU(VAR)3-9,小鼠G9a和粗糙链孢霉 DIM5的IC50分别为0.8 μM, 2.5 μM和3 μM。Chaetocin是一种抗癌药物并是 thioredoxin reductase (TrxR) 的抑制剂。
S3790 Methyl gallate Methyl Gallate (Methylgallate, Gallic acid methyl ester, Gallicin) is a plant polyphenol with antioxidant, anticancer, and anti-inflammatory activities.
S9188 Magnoflorine chloride Magnoflorine (Escholine, Thalictrine, Corytuberine methochloride), isolated from the rhizome of Sinomenium acutum and from Pachygone ovata, is usually used as an anxiolytic chemical with anti-oxidant, α-tyrosinase inhibitory and anti-inflammationary activities.
S9189 Oroxin A Oroxin A (Baicalein 7-O-glucoside), an active component isolated from the herb Oroxylum indicum (L.) Kurz, activates PPARγ and inhibits α-glucosidase, exerting antioxidant activity.
S9190 Oroxin B Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.
S9191 Loganic acid Loganic acid (Loganate) is a naturally occurring iridoid monoterpeneglusoside involved in the biosynthesis of indole alkaloids in Vinca rosea.
S9194 Toddalolactone Toddalolactone, a natural coumarin, inhibits the activity of recombinant human Plasminogen activator inhibitor-1 (PAI-1) in a dose-dependent manner, yielding an IC50 value of 37.31 ± 3.23 μM.
S9195 Maltotetraose Maltotetraose, found in many foods, belongs to the class of organic compounds known as oligosaccharides.
S9196 Calceolarioside B Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.
S9199 Pseudoginsenoside F11 Pseudoginsenoside F11, a natural product found in American ginseng but not in Asian ginseng, is a novel partial PPARγ agonist.
S9200 Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S9203 Notopterol Notopterol is a kind of furanocoumarin that possesses anti-inflammatory, analgesic, and anticancer activities.
S9204 Oroxylin A Oroxylin A (6-Methoxybaicalein) is a flavonoid isolated from Scutellaria root that exhibits multiple pharmacological activities, including anti-oxidative, anti-inflammatory, anti-viral and anti-tumor properties.
S9205 Hydroxygenkwanin Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, has anti-oxidant ability and can act as tissue factor (TF) inhibitor to prevent thrombosis.
S9206 Hydroprotopine Hydroprotopine (W1171) is a kind of natural herbal extract.
S9514 Rotundic acid Rotundic acid (Rutundic acid)是一种天然化合物,对人肝细胞癌(HepG2)、恶性黑色素瘤(A375)、SCLC(NCI-H446)、乳腺癌(MCF-7)和结肠癌(HT-29)细胞系表现出细胞毒活性。Rotundic acid 通过调节 AKT/mTOR and MAPK pathways 诱导细胞周期停滞、DNA损伤和细胞凋亡。
S9207 Gypenoside XVII Gypenoside XVII (GP-17, Gynosaponin S), a ginsenoside found in Panax species, has neuroprotective effects and is widely used to prevent cardiovascular disease.
S9208 Ginsenoside Rb3 Ginsenoside Rb3 是从人参中提取的天然产物,在心血管疾病包括心肌的缺血/再灌注(I/R)损伤中起着重要作用。在人肾293T细胞中检测了Ginsenoside Rb3(0.1-10 μM)对肿瘤坏死因子TNF-α诱导的 nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) 荧光素酶报告基因的抑制作用,IC50值为8.2 μM。在用10 ng/mL TNF-α处理后的HepG2细胞中,Ginsenoside Rb3 还以剂量依赖性的方式抑制 cyclooxygenase-2 (COX-2)inducible nitric oxide synthase (iNOS) 信使mRNA的诱导诱导表达。
S9209 Tritetradecanoin Tritetradecanoin, found in Myristica fragrans Houtt., is used as an antiadhesion agent and lubricating agent.
S9210 Ginsenoside Rk1 Ginsenoside Rk1, one of the main elements of Sung Ginseng, has been confirmed as a new endothelial barrier enhancer recently and has anti-cancer activity.
S9211 Eriocitrin Eriocitrin (eriodictyol 7-rutinoside, Eriodictyol glycoside, Eriodictioside) is a flavone glycoside mainly found in lemon with antioxidant activity.
S9213 Jujuboside A Jujuboside A, isolated from Semen Ziziphi Spinosae, exerts anti-oxidant, anti-inflammatory activities, and reduces the cell apoptosis.
S9214 Jujuboside B Jujuboside B, one of the saponins isolated from the seeds of Zizyphus jujuba var. spinosa, is used in traditional chinese medicine for treating cardiovascular diseases and neurodegenerative diseases.
S9215 Pinoresinol diglucoside Pinoresinol diglucoside, one of the major lignans isolated from Eucommia ulmoides Oliver bark, has various pharmacological functions, including antihypertension and prevention of osteoporosis.
S9216 Esculentoside A Esculentoside A, isolated from the Chinese herb phytolacca esculenta, possesses a broad inhibitory effect on a panel of pro-inflammation molecules with less toxicity.
S9217 Complanatuside Complanatuside, a flavonoid compound isolated from Astragalus complanatus and Lysimachia christinae, has anti-inflammation, lipid-lowering and hepatoprotective effects.
S9219 Huperzine B Huperzine B, a natural alkaloid existed in Lycopodium plants, is a novel acetylcholinesterase inhibitor and has neuroprotective effects.
S9221 Ferulaldehyde Ferulaldehyde (Coniferaldehyde, Ferulyl aldehyde) is a natural intermediate of polyphenol metabolism of intestinal microflora.
S9222 Dipotassium glycyrrhizinate Dipotassium glycyrrhizinate (Neubormitin) 是从甘草根中分离出来的一种广泛使用的抗炎药。
S9223 Talatisamine Talatisamine, a delphinine type alkaloid extracted from Aconitum talassicum, is a newly identified K+ channel blocker with hypotensive and antiarrhythmic activities.
S9224 Dehydroandrographolide Succinate Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
S9226 Steviolbioside Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S9228 Schisandrin C Schisandrin C, a dibenzocyclooctadiene lignan isolated from the fruits of Schisandra chinensis (Turcz.) Baill, has many characteristics including anti-inflammation, anti-tumor, and anti-oxidation.
S9229 Linderane Linderane, isolated from Lindera strychnifolia vill., is an indirect PDE3 activator and possesses multiple biological effects, including superoxide anion radical-scavenging and antioxidative activity and protective activity against gastritis, gastric ulcers and backache.
S9230 Vaccarin Vaccarin, a major flavonoid glycoside found in Semen vaccariae, exhibits extensive biological activities including vascular endothelial cell protective effects.
S9231 Schisanhenol Schisanhenol (Gomisin K3) is a compound derived from the fruit of a traditional Chinese herb Schisandra rubriflora, exhibiting strong inhibition toward UGT2B7.
S9232 Crocin II Crocin II (Crocin B, Crocetin gentiobiosylglucosyl ester, Tricrocin), a carotenoid chemical compound that is found in the flowers crocus and gardenia, is an antioxidant and neural protective agent.
S9233 Imperialine Imperialine (Sipeimine, Kashmirine) is an alkaloid found in the bulbs of species of the genus Fritillaria.
S9234 Schaftoside Schaftoside, a bioactive compound found in the Herba Desmodii Styracifolii, exhibits pancreatic lipase inhibitory activity. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission.
S9235 Didymin Didymin (Neoponcirin, Isosakuranetin-7-O-rutinoside) is a citrus-derived natural compound that kills p53 wild-type as well as drug-resistant p53-mutant neuroblastoma cells in culture. It possesses antioxidant, anti-inflammation and anti-cancer properties.
S9237 Berberrubine Berberrubine (Beroline, 9-Berberoline), an isoquinoline alkaloid isolated from many medicinal plants, possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects.
S9238 Polygalic acid Polygalic acid (Senegenic acid), a triterpenoid saponin, shows expectorant, emetic and stimulant effects.
S9239 Isocorynoxeine Isocorynoxeine (7-Isocorynoxeine)是一种在钩藤(Uncaria rhynchophylla)中发现的主要生物碱,对心、脑血管系统具有广泛的有益作用。Isocorynoxeine 可抑制 5-HT2A receptor 介导的电流反应,IC50值为72.4 μM。
S9240 Isofraxidin Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
S9242 Narirutin Narirutin (Naringenin-7-O-rutinoside, Isonaringin), a flavanone abundant in citrus fruits, possesses anti-inflammatory and anti-oxidative effects.
S9243 Protosappanin B Protosappanin B (FT-0689654, Q-100961), extracted from Lignum Sappan, possesses anti-inflammation and anti-oxidation properties.
S9244 8-O-acetyl shanzhiside methyl ester 8-O-acetyl shanzhiside methyl ester (Barlerin, ND01), isolated from the leaves of Lamiophlomis rotata Kudo, promotes angiogenesis, which leads to the improvement of functional outcome after stroke.8-O-Acetyl shanzhiside methyl ester can inhibts NF-κB.
S9245 Phellodendrine chloride Phellodendrine chloride, isolated from the Phellodrndron amurensis, exhibits immunosuppressive and anti-inflammatory activities.
S9246 Tiliroside Tiliroside, a glycosidic flavonoid, possesses anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activities.
S9247 Isoliensinine Isoliensinine is an alkaloid produced by the edible plant Nelumbo nucifera. It possesses anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities.
S9248 Homoorientin Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.
S9249 Securinine Securinine, a major natural alkaloid product from the root of the plant Securinega suffruticosa, acts as a γ-amino butyric acid (GABA) receptor antagonist.
S9250 Isosilybin Isosilybin (Silymarin, Isosilybinin, Q-100795)是一种在水飞蓟(S. marianum)果实提取物中发现的黄烷醇,具有抗氧化和抗癌活性。Isosilybin 抑制 CYP3A4 诱导,IC50为74 μM。
S9251 Oxypeucedanin Oxypeucedanin is a major coumarin aglycone that can be extracted from Ostericum koreanum. It is a kind of open-channel blocker of the hKv1.5 channel.
S9252 Corydaline Corydaline is a bioactive alkaloid with various anti-acetylcholinesterase, anti-allergic, and anti-nociceptive activities found in the medicinal herb Corydalis Tubers.
S9253 Coixol Coixol (6-methoxybenzoxazolone, MBOA) acts as a central muscle relaxant with an anti-convulsant effect.
S9254 Skimmin Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent.
S9255 Isoscopoletin Isoscopoletin (7-Methoxyesculetin) is a member of the class of compounds known as hydroxycoumarins. Isoscopoletin can be found in coriander and eggplant, which makes isoscopoletin a potential biomarker for the consumption of these food products.
S9256 Isobavachin Isobavachin is a flavonoid compound obtained from Psoralea Corylifolia Linn.
S9257 Acetylshikonin Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma. It is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s.
S9258 (+)-Isocorynoline Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.
S9260 Nodakenin Nodakenin ((+)-Marmesinin), a coumarin compound, acts as an AChE inhibitor that inhibits AChE activity in a dosedependent manner with an IC50 value of 84.7 μM.
S9265 7-Epitaxol 7-Epitaxol (7-Epipaclitaxel) is the major derivative of taxol found in cells. Taxol (paclitaxel) is a well-known natural-source cancer drug.
S9266 Ginsenoside Rc Ginsenoside Rc, isolated from Panax ginseng, may exert various activities including anti-cancer, anti-inflammatory, antiobesity, and anti-diabetic effects.
S9186 Liensinine perchlorate Liensinine is the active constituent of plumula nelambinis with anti-hypertension.
S9187 Phillygenin Phillygenin (Sylvatesmin), a bioactive intergradient in Osmanthus fragrans, has anti-inflammatory, anti-obesity and antipyretic activities. It could reduce blood lipid levels and low density lipoprotein.
S9517 Liriope muscari baily saponins C Liriope muscari baily saponins C, extracted from the roots of Liriope muscari (Decne.) Baily, induces autophagy and has an anti-thrombotic activity.
S9201 Levistilide A Levistilide A (Diligustilide), a natural compound isolated from the traditional Chinese herb Ligusticum chuanxiong Hort, is a potential P-gp modulator and used for treating cancer.
S9512 1,3-Dicaffeoylquinic acid 1,3-Dicaffeoylquinic acid (Cynarin; Cinarine; 1,5-Dicaffeoylquinic acid) is a phenolic compound found in artichoke. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.
S9114 Polyphyllin I Polyphyllin I 是从巴黎茶树素中提取的小分子单体,用于治疗传染病和癌症。 Polyphyllin I 抑制U251细胞增殖并诱导其凋亡。 Polyphyllin I 是 JNK 信号传导途径的激活剂,具有潜在的抗神经胶质瘤作用。
S9115 Wogonoside Wogonoside (Oroxindin, Wogonin 7-O-glucuronide, Glychionide B), the main flavonoid component derived from the root of Scutellaria baicalensis Georgi, displays anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities.
S9116 Chikusetsusaponin IVa Chikusetsusaponin IVa (Calenduloside F) 是三萜类皂苷的主要活性成分,具有多种药理活性,包括对各种癌细胞的细胞毒活性,抗炎活性,预防龋齿和诱导人五味子霉素肾毒性。Chikusetsusaponin IVa 也是一种新型的 AMPK 激活剂。
S9117 (20S)Ginsenoside Rg2 (20S)Ginsenoside Rg2, a constituent existing in red ginseng, has been reported to exert strong inhibitory action on various cancer cells.
S9119 Leonuride Leonuride (Ajugol), an active alkaloid that is extracted from Traditional Chinese Medicine Herba leonuri, is a terpene glycoside that can be used for some gynecological disease.
S9121 Irigenin Irigenin, an O-methylated isoflavone, can be isolated from the rhizomes of the leopard lily (Belamcanda chinensis), and Iris kemaonensis.
S9122 Tectorigenin
S9123 Eriodictyol Eriodictyol, a flavonoid extracted from yerba santa, has anti-inflammatory and antioxidant activities and taste-modifying properties.
S9125 Apigetrin Apigetrin (Cosmetin, Cosmosioside, Thalictiin, Cosmosin, Apigenin 7-glucoside), a flavonoid found in many plant leaves and seeds, has been known to possess antimutagenic, anti-cancer, antioxidant and anti-inflammatory properties.
S9126 Schizandrol B Schizandrol B (Gomisin A, Besigomsin, Wuweizi alcohol B, Gamma-Schisandrin), extracted from the fruit of Schisandra chinensis Baill., exhibits potent antitumor activities.
S9127 Carnosol Carnosol is a naturally occurring phenolic diterpene found in rosemary. It has anti-oxidant, anti-inflammatory and anti-cancer activities.
S9128 Isoacteoside Isoacteoside, a phenylethanoid isolated from Monochasma savatieri Franch. ex Maxim., is an anti‐inflammatory herb widely used in traditional Chinese medicine.
S9129 20(S)-Ginsenoside Rh1 20(S)-Ginsenoside Rh1 (Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1)是从红参中提取的主要生物活性化合物之一,在世界范围内,红参已越来越多地用于增强认知和身体健康。它具有抗发炎、抗氧化、免疫调节作用和对神经系统有积极作用的有效特性。20(S)-Ginsenoside Rh1 可抑制 PPAR-γTNF-αIL-6IL-1β 的表达。
S9130 Rubusoside Rubusoside is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties.
S9131 Punicalagin Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.
S9132 Harpagide Harpagide, isolated from the secondary roots of Harpagophytum procumbens (Hp), has valuable medicinal properties, such as anti-inflammatory, analgesic and potential antirheumatic effects.
S9133 Chicoric acid Chicoric acid (Dicaffeoyltartaric acid), identified in many plants, exerts various properties include anti-cancer, anti-obesity, antiviral, and anti-diabetic effects.
S9134 Spinosin Spinosin (Flavoayamenin), a flavone-C-glycoside, is a bioactive ingredient isolated from a traditional Chinese herb Zizyphi Spinosi Semen. It acts as a plant metabolite and an anxiolytic drug.
S9135 Artemisic acid Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.
S9136 Neochlorogenic acid Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
S9137 Erianin Erianin, a natural product derived from Dendrobium chrysotoxum, has been used as an analgesic in traditional Chinese medicine and is a potential anti-tumor agent. Erianin can inhibit IDO-induced tumor angiogenesis.
S9138 Picfeltarraenin IA Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system.
S9141 Berbamine Berbamine (BA, BBM) 是一种从中草药黄芦木中分离而来的双苄基异喹啉类天然产物。它是bcr/abl的新型抑制剂,具有有效的抗白血病活性,是NF-κB的抑制剂。Berbamine (BA, BBM) 通过靶向 Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) 抑制癌细胞的生长,并诱导人骨髓瘤细胞凋亡。
S9143 Ammonium Glycyrrhizate Ammonium glycyrrhizate (Glycamil, Glycyrram) is an ammonium salt extract isolated from licorice root and is commonly used as a flavoring agent and is also used in fragrances, and skin and hair care products.
S9144 Solasonine Solasonine, a natural glycoalkaloid compound, has anti-inflammation and anti-tumor properties.
S9145 Solamargine Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum, induces potent, non-selective cytotoxicity and P-gp inhibition.
S9146 Anwuligan Anwuligan (Macelignan), a natural compound isolated from Myristica fragrans Houtt, has antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. It also shows antioxidant, free radical scavenging, and neuroprotective activities.
S9148 Peiminine Peiminine (Verticinone, Zhebeinone, Raddeanine), a biologically active component extracted from Fritillaria walujewii Regel, has been reported to have potent anti-inflammatory, antitussive, and expectorant effects. It induces autophagic cell death thus represses colorectal carcinoma tumor growth.
S9149 Benzoylpaeoniflorin Benzoylpaeoniflorin, a natural product isolated from Chinese paeony root, could inhibit COX-1 and COX-2 in vitro.
S9150 Daurisoline Daurisoline, a bis-benzylisoquinoline alkaloid isolated from the rhizomes of Menispermum dauricum, is a potent autophagy blockers with antiarrhythmic effects.
S9151 Praeruptorin E Praeruptorin E, isolated from Peucedanum praeruptorum Dunn., is a cardiotonic agent with selective cardiac calcium channel agonistic effect.
S9152 Epiberberine Epiberberine, a natural protoberberine alkaloid, is a potent inhibitor against both ureases with IC50 values of 3.0±0.01μM for HPU (ureases from Helicobacter pylori) and 2.3±0.01μM for JBU (ureases from jack bean).
S9153 Betulinicaldehyde Betulinicaldehyde (Betulinal, Betunal), isolated from the bark of tectona grandis., is an anti-tumor agent.
S9154 Chelidonine Chelidonine (Stylophorin, Helidonine), a major bioactive, isoquinoline alkaloid ingredient in Chelidonium majus, exhibits anti-inflammatory properties and acetylcholinesterase and butyrylcholinesterase inhibitory activity.
S9155 Aurantio-obtusin Aurantio-obtusin is a natural effective compound isolated from Semen Cassiae, which possesses hypotensive and hypolipidemic effects.
S9156 Chonglou Saponin VII Chonglou Saponin VII (Dioscinin, Polyphyllin-VII, Paris saponin-VII), a kind of steroidal saponins from Chonglou (Rhizoma Paridis Chonglou), inhibits EMT and reduces the invasion of ovarian cancer cells via the GSK-3β/β-catenin signaling pathway.
S9157 Neoandrographolide Neoandrographolide, a principle diterpenoids isolated from A. paniculata, exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities.
S9159 momordin-Ic Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.
S5742 Deferoxamine mesylate Deferoxamine mesylate是Deferoxamine的甲磺酸盐,它可形成铁络合物并用作螯合剂。Deferoxamine 是一种铁死亡的抑制剂,可在体外低氧和高血糖状态下稳定 HIF-1α 的表达并改善HIF-1α的活性。Deferoxamine 可降低 beta-amyloid (Aβ) 的沉积并诱导自噬。请不要用生理盐水或者PBS配制储存液,可能会产生沉淀。
S9160 Ziyu-glycoside I Ziyuglycoside I is one of the major active ingredients in Sanguisorba officinalis and could be used as an active ingredient for cosmetics.
S9161 Ziyuglycoside II Ziyuglycoside II is an active compound of Sanguisorba officinalis L. that has anti-inflammation, antioxidation, antibiosis, and homeostasis properties.
S9162 Rubimaillin Rubimaillin (Mollugin), found in the Chinese medical plant Rubia cordifola, is a dual inhibitor of acetyl-CoA cholesterol acyltransferase 1 (ACAT1) and acetyl-CoA cholesterol acyltransferase 2 (ACAT2), but is more selective for the ACAT2 isozyme.
S9163 Rhapontigenin Rhapontigenin (Protigenin), produced from rhapontin isolated from a methanol extract of Rheum undulatum roots by enzymatic transformation, is a selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM).
S9164 Curdione Curdione, one of the major components of Curcuma zedoaria, shows an excellent antithrombotic activity in vivo.
S9165 Poncirin Poncirin (Isosakuranetin-7-neohesperidoside), extracted from trifoliate orange, has anti-bacterial and anti-inflammatory activities.
S9167 Columbin Columbin, a diterpenoid furanolactone, is a potential anti-inflammatory drug.
S9168 Periplogenin Periplogenin (Desoxostrophanthidin, 5-beta-Hydroxydigitoxigenin), isolated from Lagenaria siceraria, has potent anti-psoriatic effects in vitro and in vivo.
S9171 Harpagoside Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects.
S9172 Phellodendrine Phellodendrine, a quaternary ammonium alkaloid extracted from the dried bark of Phellodendrom chinensis Schneid and Phellodendrom amurense Rupr, has the effect of suppressing cellular immune response, reducing blood pressure and antinephritis.
S9173 Sec-O-Glucosylhamaudol Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) is one of the major bioactive compounds of the Saposhnikoviae Radix.
S9174 Xanthotoxol Xanthotoxol (8-Hydroxypsoralen, 8-Hydroxypsoralene, 8-Hydroxyfuranocoumarin, Psoralen), a biologically active linear furocoumarin found in a large number of plants, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
S9175 Macranthoidin A Macranthoidin A, found in the herbs of Lonicera japonica Thunb., has anti-inflammation activity.
S9176 Pimpinellin Pimpinellin is a furocoumarin that acts as antagonist of proteins with GABA receptor activity.
S9177 Gypenoside XLIX Gypenoside XLIX, a naturally occurring gynosaponin, is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator.
S9178 Sinapine thiocyanate Sinapine thiocyanate is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities.
S9179 Catharanthine hemitartrate Catharanthine hemitartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine.
S9180 Tussilagone Tussilagone, isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is used as a traditional oriental medicine for asthma and bronchitis. It shows anti-inflammatory activity in in vitro studies.
S9181 Periplocin Periplocin (Periplocoside)是从传统草药皮质骨膜中提取的,具有心脏和抗癌活性。Periplocin 可以显著地促进成纤维细胞L929细胞的增殖、迁移和刺激胶原蛋白的产生,这取决于 Na/K-ATPase 介导的Src/ERK和PI3K/Akt信号通路的激活,从而促进伤口愈合 。
S9182 Crebanine Crebanine, an aporphine alkaloid isolated from the crude hexane extract of the dried tuber of Stephania venosa, exhibits anti-cancer effects.
S9183 Ruscogenin Ruscogenin, a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been reported to exert significant anti-inflammatory and anti-thrombotic activities.
S9184 Forsythoside B Forsythoside B 是从中药民间植物轮枝(Lamiophlomis rotata Kudo)的叶子中分离出来的一种苯乙胺类苷。Forsythoside B 具有有效的神经保护作用,并具有抗发炎、抗氧化和防腐特性。Forsythoside B 可以抑制 TNF-alphaIL-6IκB 并调节 NF-κB
S9185 Nitidine Chloride Nitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity.
S9455 Isorhamnetin 3-O-neohesperoside Isorhamnetin 3-O-neohesperoside is the major active substance of Puhuang, a traditional herb medicine widely used in clinical practice to tackle many chronic diseases. It has significant biological and pharmacological activities, including antioxidant, antiatherogenic and antimicrobial effects.
S9511 Crocin I Crocin-I是藏红花素家族的主要成员之一,具有抗抑郁活性,并可改善慢性皮质酮诱导的小鼠脂质代谢破坏和肠道菌群失调。
S9515 Polyphyllin VII Polyphyllin VII (Y-0166), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocellular carcinoma and osteosarcoma.
S5129 D-Aspartic acid D-Aspartic acid (D-Asp, Aminosuccinic acid, asparagic acid, asparaginic acid) is an endogenous amino acid occurring in several tissues and cells of both invertebrates and vertebrates. It can regulate testosterone synthesis and may act on a stimulatory receptor (NMDA).
S9055 Salvianolic acid A Salvianolic acid A (Dan Phenolic Acid A), a water-soluble compound extracted from Radix Salvia miltiorrhiza (Danshen), is an antioxidant and free radical scavenging compound that also acts as an inhibitor of the protein-protein interaction mediated by SH2 domains of Src-family kinases Src and Lck.
S9052 Auraptene Auraptene (7-geranyloxycoumarin)是源自柑橘类植物的天然香豆素,具有重要的药理特性,包括抗癌,抗炎,抗幽门螺杆菌,抗原毒性和神经保护作用。Auraptene 可抑制 matrix metalloproteinase 2 (MMP-2) 以及关键的炎症介质,包括 IL-6IL-8chemokine (C-C motif) ligand-5(CCL5)
S9045 Triptophenolide Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A.
S9061 Hydroxy safflor yellow A Hydroxy safflor yellow A, a monomer extracted from Carthamus tinctorius L., possesses various kinds of bio-activities, including anti-oxidation, anti-inflammatory actions, anti-platelet aggregation, anti-tumor and anti-myocardial injury effects.
S9062 4-Hydroxyisoleucine 4-Hydroxyisoleucine, an atypical branched-chain amino acid derived from fenugreek, has effects on the glucose and lipid metabolism, stimulates glucose-dependent insulin secretion and reduces insulin resistance in muscle and/or liver.
S9063 Harringtonine Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
S9064 Trilobatin Trilobatin (P-Phlorizin), a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
S9065 Songorine Songorine, a ubiquitous alkaloid in the genus Aconitum, is a novel antagonist of the GABAA receptor in rat brain and has antiarrhythmic, antinociceptive, anti-inflammatory, regenerative and CNS-modulating properties.
S9066 Specnuezhenide Specnuezhenide (Nuezhenide), one of the main ingredients of Chinese medicine, has anti-angiogenic and vision improvement effects.
S9067 Pseudoprotodioscin Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9068 Trillin Trillin (Disogluside, Diosgenin glucoside) is an active ingredient isolated from Trillium tschonoshii Maxim and acts as a potential anti-inflammatory drug for chronic hepatic inflammation.
S9069 Jatrorrhizine chloride Jatrorrhizine chloride (Neprotine, Yatrorhizine) is the hydrochloride salt form of jatrorrhizine, which is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
S9070 Isoxanthohumol Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
S9072 Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S9073 Lithospermoside Lithospermoside (Griffonin), extracted from the roots of Lithospermum purpurocaeruleum and L.officinale (Borginaceae), and Thalictrum rugosum and T. dasycarpum (Ranunculaceae), has anti-oxidant, anti-tumor promoting activities.
S9074 Buddlejasaponin IVb Buddlejasaponin IVb (Saikosaponin 1b), a major component of Pleurospermum kamtschaticum, exerts anti-inflammatory and cytotoxic effects against cancer cells.
S9075 Mulberroside A Mulberroside A 是从 Morus alba 根的乙醇提取物中分离出的,具有抗酪氨酸酶和抗氧化活性,并被广泛用作化妆品中的活性成分。Mulberroside A 降低 TNF-αIL-1βIL-6 的表达并抑制 NALP3caspase-1NF-κB 的激活以及 ERKJNKp38 的磷酸化。
S9076 Typhaneoside Typhaneoside is a flavonoid glycoside plant extract that has an inhibitory effect on the proliferation of human umbilical arterial smooth muscle cell(HUASMC).
S9077 Plantamajoside Plantamajoside (Y0160, C10485), a hydroxycinnamic acid, is used as a biomarker in chemotaxonomical studies, and is a compound with numerous biological applications and considerable pharmacological potential.
S9078 Epigoitrin Epigoitrin (Goitrin, BA-51-090278), the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.
S9079 Ginsenoside Rb2 Ginsenoside Rb2 (Ginsenoside C) is a ginsenoside found in Panax ginseng that has a role as a plant metabolite, an antiviral agent and a hypoglycemic agent.
S9080 Anhydroicaritin Anhydroicaritin (Cycloicaritin), a prenylated flavonoid natural product, is commonly recognized as one of the effective compounds of Epimedii Herba and exhibits a variety of biological activities, such as activation of cancer cell apoptosis and inhibition of growth, protection against beta amyloid-induced neurotoxicity, and promotion of neuronal and cardiac cellular differentiation. It is a potent inhibitor of transcription factor SREBPs.
S9081 Anemoside B4 Anemoside B4 (Pulchinenoside B4, Chinensioside A, Pulchinenoside C, Pulsatilla saponin B4), extracted from the herb of Pulsatilla chinensis (Bge.) Regel, is a potential antiviral constituent and inhibits the secretion of IL-10.
S9082 Manninotriose Manninotriose, found in many foods, is a novel and important player in the RFO metabolism of red dead deadnettle.
S9083 Rhapontin Rhapontin (Ponticin, Rhaponticin, Rhapontigenin glucoside), a stibene-type glycoside distributed widely in medicinal plants of Rheum genus (Polygonaceae), has anti-inflammatory effect and anti-proliferative activity.
S9084 Rhoifolin Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
S9085 Corynoline Corynoline is one of the major active components of many ethnopharmacological plants and exhibits anti-tumor, anti-inflammatory and hepatoprotective activities, etc.
S9111 Isorhamnetin Isorhamnetin (3-methylquercetin, 3'-Methoxyquercetin, Isorhamnetol), a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.
S9112 Kaempferitrin Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
S9113 Ononin Ononin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects.
S9101 Ingenol Ingenol, a plant-derived diterpenoid, is a weak PKC activator and possesses important anticancer activity.
S9019 Quillaic acid Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and shows strong anti-inflammatory activity.
S9020 Dihydrotanshinone I Dihydrotanshinone I (15,16-dihydrotanshinone I) is a naturally occurring compound extracted from Salvia miltiorrhiza Bunge, also known as Chinese sage, red sage root, and the Chinese herbal Dan Shen. It is a potent inhibitor of the HuR:RNA interaction, active in the low nanomolar range, mainly by limiting the association rate of HuR with RNA.
S9021 (20R)Ginsenoside Rg3 (20R)Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It has a role as an antioxidant and a plant metabolite.
S9022 20S-Ginsenoside Rg3 20S-Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It exihits neuromodulatory, cognition enhancing, anti-inflammatory, antioxidative, anti-angiogenic, and anticancer activities.
S9023 20S-Ginsenoside Rh2 20S-Ginsenoside Rh2 is a ginsenoside found in Panax species and inhibits cancer development, progression, and metastasis.
S9026 Hastatoside Cimifugin is a bioactive component of Saposhnikovia divaricata, a Chinese herb for treating allergy.
S9029 Prim-o-glucosylcimifugin Prim-O-glucosylcimifugin (Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside) 是防风(Radix Saposhnikovia)中的主要成分,长期以来一直应用于传统中医药中治疗发热、风湿和癌症,它表现出潜在的抗癌活性。在LPS激活的 RAW 264.7 巨噬细胞,Prim-O-glucosylcimifugin 可以浓度依赖性的方式下调 NO synthase (iNOS)cyclooxygenase 2 (COX-2) 的mRNA和蛋白质表达。
S9031 Gambogenic acid Gambogenic Acid, identified from Gamboge, is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects. Gambogenic acid acts is also an effective inhibitor of EZH2 that specifically and covalently binds to Cys668 within the EZH2-SET domain, and triggers EZH2 ubiquitination.
S9034 Isochlorogenic acid C Isochlorogenic acid C (3,4-Dicaffeoylquinic acid; 4,5-Dicaffeoylquinic acid), which is a di-O-caffeoyl derivative of chlorogenic acid, is a well-known antioxidant from herbal plants and shows anti-viral effects against EV71.
S9039 Albiflorin Albiflorin, a natural product isolated from Paeoniae Radix, is a novel 5-HT and NE reuptake inhibitor with high selectivity.
S9040 Maslinic acid Maslinic Acid (Crategolic Acid, 2α-Hydroxyoleanoic Acid), a Natural Triterpene, exerts a wide range of biological activities, i.e. antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. MA significantly suppresses the DNA-binding activity of NF-κB p65 in LPS-induced RAW 264.7 cells.
S9054 Pectolinarin Pectolinarin 是Cirsium setidens的一种主要化合物,具有抗炎活性。Pectolinarin 可抑制 IL-6IL-8 的分泌以及 PGE2NO 的产生。Pectolinarin 通过 PI3K/Akt 信号通路的失活来诱导凋亡。
S9050 Boldine Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.
S9049 Parishin A Parishin A, isolated from the rhizomes of Gastrodia elata, has good neuroprotective effects against brain disorders.
S9060 Nystose Nystose (1,1-Kestotetraose, Fungitetraose), a constituent of seeds of onions and roots of Asparagus, is a low-calorie sweetening agent for food and chewing gum.
S9092 Norisoboldine Norisoboldine (Laurelliptine), a natural aryl hydrocarbon receptor (AhR) agonist, attenuates ulcerative colitis (UC) and induces the generation of Treg cells.
S9093 Nardosinone Nardosinone, isolated from Nardostachys root, an important Chinese herbal medicine, is an enhancer of nerve growth factor and possesses a wide range of pharmacological effects, including sedative, adaptogen-like, anti-depressive, anti-leukemic, anti-tumorous, and anti-trypanosomal activities.
S9097 Alisol B Acetate Alisol B acetate, a triterpene from Alismatis rhizoma, induces Bax up-regulation and nuclear translocation, the activation of initiator caspase-8 and caspase-9, and executor caspase-3, suggesting the involvement of both extrinsic and intrinsic apoptosis pathways.
S9098 Dehydrodiisoeugenol Dehydrodiisoeugenol, a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae), acts as a potent anti-inflammatory agent and shows various pharmacological activities, including anti-lipid peroxidation, anti-bacteial function, and hepatic drug metabolism enzyme inhibition.
S9099 Orientin Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
S9100 Fraxinellone Fraxinellone is a natural product isolated from the D. dasycarpus plant, which has been shown to exhibit neuroprotective and anti-inflammatory activities.
S9102 Magnolin Magnolin is a natural compound abundantly found in Magnolia flos targeting ERK1 (IC50=87 nM) and ERK2 (IC50=16.5 nM) and inhibits cell transformation induced by tumor promoters such as epidermal growth factor (EGF).
S9103 Ginsenoside Ro Ginsenoside Ro (Chikusetsusaponin V), one of the high-abundance saponins in ginseng, is widely used as a dietary supplement and has many health-promoting effects.
S9104 Maltopentaose Maltopentaose is a substrate for energy metabolism and carbon for E. coli.
S9105 Ginsenoside CK Ginsenoside CK is a ginsenoside found in Panax species and has a role as a plant metabolite, an antineoplastic agent, a hepatoprotective agent, an anti-allergic agent and an anti-inflammatory agent.
S9108 Timosaponin A3 Timosaponin A3 (Filiferin B, AneMarsaponin A3), one of the major steroidal saponin components isolated from Anemarrhena asphodeloides, displays promising pharmacological activity in improving learning, memory, and antineoplastic activity.
S9056 Tuberostemonine Tuberostemonine, a natural product found in Stemona phyllantha and Stemona tuberosa, is an alkaloid and a metabolite.
S9053 Irisflorentin Irisflorentin derived from the roots of Belamcanda chinensis (L.) DC. is an herb which has been used for the treatment of inflammatory disorders in traditional Chinese medicine.
S9051 Asperuloside Asperuloside, an iridoid glycoside found in Herba Paederiae, is a component from traditional Chinese herbal medicine and exerts anti-inflammatory effect.
S9048 (+)-Gallocatechin (+)-Gallocatechin, found notably in green tea, has moderate affinity to the human cannabinoid receptor and acts as an antioxidant.
S9057 Sinigrin Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.
S9058 Gallocatechin gallate Gallocatechin galleate (GCG) is a polyphenol originally derived from a variety of sources, including green tea, coffee, safflower, and almonds.
S9086 Dihydrocapsaicin Dihydrocapsaicin (6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589), found in pepper (C. annuum), is a potential nutriceutical.
S9088 Calycosin-7-O-beta-D-glucoside Calycosin-7-O-beta-D-glucoside, an isoflavone glycoside isolated from A. mongholicus and A. membranaceus, has antioxidant, anti-inflammatory, and neuroprotective biological activities.
S9089 Magnoflorine Magnoflorine (Escholin, Thalictrin), an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase.
S9090 Corilagin Corilagin, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. It is an inhibitor of TNF-α.
S9091 10-Gingerol 10-Gingerol is a bioactive compound found in ginger with anti-inflammatory and antioxidant activity.
S9095 Senegenin Senegenin (Tenuigenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity.
S9096 ligustroflavone Ligustroflavone (Nuezhenoside), isolated from the leaves of Turpinia montana, shows high antioxidant capacity and is reported to be an AMPK activator.
S9106 Eleutheroside E Eleutheroside E, a principal component of Eleutherococcus senticosus (ES), has anti-inflammatory effects by inhibiting NF-κB and protecting against myocardial infarction.
S9107 Glycitein Glycitein is an aglycone isoflavone found in soy and red clover and exhibits a wide variety of beneficial properties, including neuroprotective, antioxidative, anticancer, anti-osteoporotic, and anti-atherosclerotic activities.
S9109 1-Kestose 1-Kestose (1F-beta-D-Fructosylsucrose), a fructooligosaccharide, could efficiently stimulates Faecalibacterium prausnitzii as well as Bifidobacteria in humans.
S9110 Morin Morin (Al-Morin, Aurantica, Calico Yellow, Toxylon pomiferum), a constituent of various woods, has a role as an antioxidant, a metabolite, an antihypertensive agent, a hepatoprotective agent, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent, an antibacterial agent, a DNA topoisomerase inhibitor and an angiogenesis modulating agent.
S4700 4-Aminobutyric acid (GABA) 4-Aminobutyric acid (4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid)是一种天然存在的神经递质,具有抑制中枢神经系统的活性。
S5580 Arabic gum Arabic gum, derived from exudates of Acacia senegal or Acacia seyal trees, is a complex polysaccharide indigestible to both humans and animals and considered as a safe dietary fiber.
S3774 Dehydroandrographolide Succinate Potasium Salt Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.
S9008 20-Deoxyingenol 20-Deoxyingenol is a natural compound isolated from the seeds of Euphorbia lathyris L.
S5145 Protoporphyrin IX (PPIX) Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.
S5288 Estropipate Estropipate (Piperazine estrone sulfate, Estrone sulfate piperazine salt, Pipestrone) is a natural estrogenic substance composed of estrone sulfate and piperazine and is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms.
S3917 Tetrahydrocurcumin Tetrahydrocurcumin (Tetrahydrodiferuloylmethane, Tetrahydro Curcumin), a major metabolite of curcumin, possesses strong antioxidant and cardioprotective properties.
S5675 Yamogenin Yamogenin, a sapogenin found in fenugreek, inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes.
S5373 Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
S5676 Zearalenone Zearalenone (F2 toxin, RAL) is a non-steroidal estrogenic mycotoxin that acts by binding the estrogen receptor (ER).
S5678 trans-Zeatin-riboside Zeatin Riboside is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process, and activate gene expression and metabolic activity.
S5705 Raceanisodamine Raceanisodamine (7β-Hydroxyhyoscyamine) is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.
S3843 Madecassoside Madecassoside (Asiaticoside A)是积雪草草药的主要活性三萜烯成分,积雪草是一种传统中药,用于治疗创伤修复和疤痕管理。
S5560 Midecamycin Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S5559 Tetrahydropalmatine Tetrahydropalmatine, a plant alkaloid used as an ingredient in dietary supplement products, is a potent and selective D1 receptor antagonist.
S5466 Saikosaponin A Saikosaponin A is a triterpene saponin derived from the medicinal plant, Bupleurum chinensis DC. (Umbelliferae). It has a variety of pharmacological benefits, including anti-inflammatory, immunomodulatory, and anti-bacterial activities.
S5622 Prohydrojasmon Prohydrojasmon is a newly launched plant growth regulator, which has jasmonic acid activity.
S5493 Atropine sulfate Atropine Sulfate (Sulfatropinol, Atropette, Tropintran) is the sulfate salt of atropine, which is a natural alkaloid anticholinergic agent and has potent antimuscarinic effects.
S5102 Stachyose Stachyose is a natural sugar found in many foods like beans and vegetables.
S4545 Warfarin Warfarin是一种广泛使用的抗凝剂,用来抗血栓形成和血栓栓塞、阻止血管中血凝块的形成和迁移。此产品为危化品(急性毒性/易燃/皮肤腐蚀),请在穿戴防护面罩、防护手套和防护服后使用。
S3991 Ketoisophorone Ketoisophorone (4-Oxoisophorone), also known as 4-Oxoisophorone, is the major component of saffron spice.
S3992 D-(+)-Trehalose dihydrate Trehalose是一种非还原糖,提高植物和动物对脱水的抵抗力。
S3993 Ethyl Vanillate Ethyl vanillin (Bourbonal, Ethylprotal) 是一种香草醛类似物,可用作调味剂和杀真菌剂,具有很强的抗氧化活性。Ethyl Vanillate 抑制 17β-HSD2 的IC50值为1.3 µM。
S3994 Methyl Cholate Methyl Cholate (Cholic acid methyl ester) is methyl ester form of Cholic acid that is a primary bile acid mainly produced by the liver.
S3995 Guaiazulene Guaiazulene (Azulon, Vetivazulen) 是一种双环倍半萜烯,是一些精油的组成成分。
S3996 Thioctic acid Thioctic acid (DL-α-Lipoic acid)是环状二硫抗氧化剂,可与其还原性二硫酚形式相互转换。
S3998 (+)-α-Lipoic acid (+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid)是thioctic acid的生理形式之一,是一种强效的抗氧化剂,可减轻糖尿病神经性症状。它比其外消旋体具有更优越的抗氧化性。R(+)-α-lipoic acid 是线粒体酶复合物的必要辅助因子。R(+)-α-lipoic acid 抑制 NF-κB 依赖性HIV-1 LTR 活化。
S5157 Thymol Thymol (2-isopropyl-5-methylphenol, IPMP), a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro.
S5161 1-Octacosanol 1-Octacosanol (n-Octacosanol, Octacosyl alcohol, Octanosol, Montanyl alcohol, Cluytyl alcohol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. It is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties.
S5172 1-Triacontanol 1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.
S5143 Citropten Citropten (5,7-Dimethoxycoumarin, Citroptene, Limettin, Limetin) is a natural organic compound which belongs to coumarins and derivatives class.
S5142 D-(+)-Melezitose Melezitose (D-Melezitose, (+)-Melezitose, D-melicitose, (+)-melicitose, melicitose) is a nonreducing trisaccharide sugar that is produced by many plant sap eating insects.
S5141 Pyrithioxin Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
S5132 Casanthranol Casanthranol is a purified mixture of te antranol glycosides derived from Cascara sagrada.
S5128 Orsellinic acid ethyl ester Orsellinic acid (Ethyl Orsellinate), a phenolic acid, is of importance in the biochemistry of lichens, from which it can be extracted.
S4954 Djenkolic Acid Djenkolic Acid (Jengkolic acid, Djenkolate, S,S'-Methylenebiscysteine) is a naturally occurring sulfur-containing amino acid extracted from djenkol beans. It is toxic to humans, often causing kidney failure.
S4827 Manganese chloride Manganese chloride在自然界中以矿物质形式存在。它常被用作其他锰化合物的合成前体。
S4969 Tropine Tropine (Pseudotropine, 3alpha-Tropanol) 是一种天然存在的莨菪烷生物碱,是多种具有生物活性的生物碱合成的中间体,这些生物碱大多具有有效的神经学作用。
S4940 Maltol Maltol (Larixinic acid, Palatone, Veltol)是一种天然有机化合物,可作为香味增强剂和调味剂。
S4859 TriacetonaMine TriacetonaMine (Tempidon, Tmpone, Odoratine, Vincubine),作为一种哌啶酮(Piperidinone),是一种具有极弱酸性的化合物,存在于绿色植物和茶中。
S4864 2-Furoic acid 2-Furoic acid (2-Furancarboxylic acid, Pyromucic acid, 2-Carboxyfuran, α-furancarboxylic acid, α-furoic acid)是一种广泛用于食品生产的有机化合物,作为防腐剂和增味剂。
S4949 Nonanoic acid Nonanoic acid (Pelargonic acid, Nonoic acid) 是一种天然存在于蔬菜和动物脂肪中的脂肪酸。
S4862 Squalene Squalene (Spinacene, Supraene, trans-Squalene),自然存在于植物、动物和人体中,是一种添加在疫苗中佐剂,用于增强免疫反应。
S4943 Isovanillin Isovanillin (5-Formylguaiacol, 3-Hydroxy-p-anisaldehyde, 3-Hydroxy-4-methoxybenzaldehyde)是醛脱氢酶(aldehyde oxidase)的可逆性抑制剂。它被广泛用作药物中间体,应用于食物和饮料行业、化学合成香料和化学分析领域。
S4951 L-Threonine L-Threonine是一种必需氨基酸,处于活化形式。它对于胶原蛋白、弹性蛋白和牙釉质的形成十分重要,连同天冬氨酸、甲硫氨酸一起发挥滋养肝脏、抗脂肪肝的作用。
S4952 Fumaric acid Fumaric acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) 是三羧酸循环中的中间产物。细胞利用三羧酸循环从食物中产生能量(ATP形式)。Fumaric acid还是尿素循环的产物。
S4953 Usnic acid Usnic acid (Usniacin)是存在于lichen(地衣)中的一种呋喃二酮,广泛应用于化妆品、除臭剂、牙膏和药用霜、中草药成品中。它具有抗病毒、抗原生动物、抗增殖和抗炎、止痛活性。Usnic acid 可通过抑制VEGFR2介导的 AKTERK1/2 信号通路来抑制乳腺肿瘤血管生成和生长。
S4960 Jasmone Jasmone是一种天然有机化合物,分离自茉莉花油的挥发成分。
S4957 Linalool Linalool (Phantol)是一些芳香剂中的香精油的主要成分。它是NMDA receptors的竞争性拮抗剂。
S4941 Farnesol Farnesol是一种天然的倍半萜烯醇,有效地治疗抗代谢障碍、具有抗炎、抗氧化、抗肿瘤和抗菌活性。
S5122 Abietic Acid Abietic acid (Sylvic acid, Abietate, Rosin Acid), an abietane diterpenoid, inhibited soybean 5-lipoxygenase with an IC50 of 29.5 ± 1.29 μM.
S5126 Aleuritic Acid Aleuritic Acid (Aleuritolic acid, 9,10,16-trihydroxy-palmitic acid), a major constituent acid of lac resin (shellac), is isolated from the resin and mainly used in the perfumery industry as a starting material for the preparation of "musk" aroma compounds as well as medicinal and bioactive compounds.
S5134 D(-)-Arabinose D-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast.
S5135 Hydroferulic acid Hydroferulic acid (Dihydroferulic acid, Dihydroconiferylic acid) is classified as a member of the phenylpropanoic acids. It is slightly soluble in water and acidic.
S4828 Sodium carbonate Sodium Carbonate (Disodium carbonate, Soda Ash, Carbonic acid disodium salt) 是碳酸的二钠盐形式,具有碱化特性。
S4939 cis-Aconitic acid Cis-Aconitic acid (cis-aconitate, Achilleic acid, Citridinic acid, Equisetic acid, Pyrocitric acid)是三羧酸循环中的中间产物,由柠檬酸脱水形成。
S4946 2,3-Dihydroxybenzoic acid 2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) 是一种天然酚类,存在于西印度醋栗和水生蕨类Salvinia molesta,也是人体中阿司匹林的代谢产物。它是一种潜在的铁螯合药物,具有抗菌特性。
S4893 Cytosine Cytosine (4-Amino-2-hydroxypyrimidine, Cytosinimine)是存在于DNA和RNA中的四种主要碱基中的一种,被细胞用于储存和传输遗传信息。
S4958 Glycocholic acid Glycocholic acid (Cholylglycine, Glycocholate) 是一种天然的次级胆汁酸,参与脂肪的乳化。
S4820 Diastase Diastase是天然存在的、可催化淀粉分解为麦芽糖的酶。
S4959 Skatole Skatole (3-methylindole, Scatole)是一种具有轻度毒性的白色结晶有机化合物,天然存在于排泄物中,具有相当广泛的抑菌作用。
S4963 Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin)是从茜草根和其他茜草科植物家族中分离出的天然色素。它具有抗血管生成、抗菌、抗氧化活性。Purpurin 可有效地抑制CYP1A1、CYP1A2 和 CYP1B1。
S4966 4-Methylesculetin 4-methylesculetin是香豆素衍生物,具有强大的抗氧化和抗炎活性。4-Methylesculetin 可抑制 myeloperoxidase (MPO) 活性并降低 IL-6 水平。
S4968 Cholesteryl Acetate Cholesteryl Acetate (Acebrochol, Cholesterol, Cholesterin),天然存在于不同液体、器官和食物中,是一种正常的人类胆甾醇酯。
S4830 Maltose Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose),一种能够提供能量的非必需营养物,是糖原和淀粉的肠道消化过程中的中间产物,存在于发芽的谷物或其他植物、蔬菜中。
S5160 4-Methoxysalicylic acid 4-Methoxysalicylic acid (2-Hydroxy-p-anisic Acid), an arabinose derivative, is used in the synthesis of 1,3,4-oxadiazole derivatives.
S5162 Isovanillic acid Isovanillic acid (Acide isovanillique, 3-Hydroxyanisic acid, 3-Hydroxy-p-anisic acid), a metabolite of isovanillin, is a selective inhibitor of aldehyde oxidase.
S5163 7-Methoxycoumarin 7-Methoxycoumarin (Herniarine), also known as Herniarin, is a methoxy derivative of coumarin and substrate for dealkylase. It has been used in the synthesis of anti-first-pass effect compounds and detergents.
S3950 Maltitol Maltitol (Maltisorb, 4-O-α-glucopyranosyl-D-sorbitol) is a sugar alcohol (polyol) used as a sugar substitute. It is especially useful in the production of sweets, including sugarless hard candies, chewing gum, chocolates.
S3951 Tannic acid Tannic acid (Gallotannic acid) 是一种多酚化合物,是一种具有抗血管生成,抗炎和抗肿瘤活性的 CXCL12/CXCR4 的抑制剂。
S5113 Propyl gallate Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.
S4799 Indole-3-acetic acid Indole-3-acetic acid (indolylacetic acid, 1H-Indole-3-acetic acid, indoleacetic acid, heteroauxin, IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.
S5167 Benzyl cinnamate Benzyl cinnamate (Cinnamein, Benzylcinnamoate, Benzyl 3-phenylpropenoate, Cinnamic acid benzyl ester), a flavouring agent isolated from various plant species, is used in heavy oriental perfumes and as a fixative.
S5168 Anthraquinone Anthraquinones (Anthradione, anthracenedione, dioxoanthracene) are the main active constituents in herbs often used to relieve constipation.
S5174 Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.
S5175 (-)-Ambroxide Ambroxide, a naturally occurring terpenoid, is one of the key constituents responsible for the odor of ambergris and an autoxidation product of ambrein.
S4762 2,4-Dihydroxyacetophenone 2,4-Dihydroxyacetophenone (Resacetophenone, 4-Acetylresorcinol) is a plant metabolite that can act as a qualitative reagent for ferric iron.
S4765 Syringaldehyde Syringaldehyde (Syringic aldehyde) is an organic compound that occurs naturally in trace amounts. It possesses worthy bioactive properties and is, therefore, used in pharmaceuticals, food, cosmetics, textiles, pulp and paper industries, and even in biological control applications.
S4768 Melibiose Melibiose (Galalpha1-6Glcbeta) is a nondigestible disaccharide that consists of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage.
S5110 Safflower Yellow Safflower Yellow (Safflor Yellow, SY), the main active constituent of the traditional Chinese medicine Safflower, is known as a neuroprotective agent that indirectly attenuates neuroinflammation.
S5116 Bilibubin Bilibubin (Bilirubin) is a tetrapyrrole and a breakdown product of heme catabolism that acts as a physiological, chain-breaking antioxidant.
S4769 L-5-Hydroxytryptophan 5-Hydroxytryptophan (5-HTP, L-oxitriptan), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
S4770 Creatine phosphate disodium salt Phosphocreatine, also known as creatine phosphate (CP) or PCr (Pcr), is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle and the brain to recycle adenosine triphosphate, the energy currency of the cell.
S4771 β-thujaplicin β-Thujaplicin (β-TH, Hinokitiol, 4-Isopropyltropolone) is a toxic tropolone derivative present in the heartwood of western red cedar (Thuja plicata) and is used as a preservative and antimicrobial additive in a number of commercial goods. Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.
S4772 alpha-Asarone Alpha (α)-asarone (trans-Asarone) is one of the main pharmacologically active compounds present in Acorus calamus Linn (Acoraceae), Acorus tatarinowii Schott (Acoraceae), and Acorus gramineus Solander. It has anticonvulsant, neuroprotective, anxiolytic and nootropic effects.
S4774 Xanthurenic Acid Xanthurenic acid (xanthurenate, 8-Hydroxykynurenic acid, 4,8-Dihydroxyquinaldic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).
S4777 Plumbagin Plumbagin (Plumbagine, Plumbaein, Plumbagone), a quinoid constituent isolated from the root of the medicinal plant Plumbago zeylanica L, exerts anticancer and antiproliferative activities in animal models and in cell culture.
S3896 (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine is an intermediate in organic synthesis.
S3897 (-)-Arctigenin (-)-Arctigenin, a lignan found in certain plants of the Asteraceae, exerts biological activities including anti-inflammatory, antiviral and anticancer.
S4781 Xanthoxyline Xanthoxylin (Brevifolin), isolated from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree), is a cytotoxic and fungicidal compound with the characteristics of a typical phytoalexin.
S3899 Hederagenin Hederagenin (Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E) is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. Hederagenin inhibits LPS-stimulated expression of iNOS, COX-2, and NF-κB.
S3900 Betulonic acid Betulonic acid (Liquidambaric acid), derived from betulinol, a pentacyclic styrene, has shown a highly specific anti-prostate cancer activity in in vitro cell cultures.
S4783 Benzyl isothiocyanate Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.
S3902 Ursonic acid Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents.
S4784 Phloracetophenone Phloracetophenone, or 2,4,6-trihydroxyacetophenone (THA), the aglycone component of phloracetophenone glucoside, is a naturally occurring compound obtained from the rhizome of Curcuma comosa (Family Zingiberaceae).
S3903 Lycorine Lycorine (Galanthidine, Amarylline, Narcissine, Licorine, Belamarine) is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.
S3904 Isoimperatorin Isoimperatorin, a natural furanocoumarin that can be isolated from a variety of plant parts, has analgesic, antimicrobial, vascular relaxing and anticancer activities.
S3905 Iso-Steviol Isosteviol (ISV) is mainly obtained by acid hydrolysis of stevioside, the sweet food additive extracted from the plant Stevia Rebaudiana Bertoni (Bertoni). It possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, and antioxidant effects.
S4788 L-α-Phosphatidylcholine L-α-phosphatidylcholine, a surfactant and a constituent of the liposomal carrier system, has shown hepatoprotection in the various hepatotoxicity model.
S4791 S-allyl-L-cysteine S-Allyl cysteine (SAC, S-Allylcysteine), a natural constituent of fresh garlic, has antioxidant and anticancer properties in animals.
S4793 Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
S4809 3-Indolepropionic acid 3-Indolepropionic acid (IPA, indole-3-propionic acid), a gut microbial metabolite, is a potent neuroprotective antioxidant and plant auxin.
S5124 DL-Citrulline L-Citrulline (Citrulline, Cit) is a naturally occurring nonessential amino acid which is the key intermediate in the urea cycle.
S5136 Calcium folinate (Leucovorin calcium) Calcium folinate is a metabolically active, reduced form of folic acid that is rapidly absorbed and extensively metabolized in the liver to other folic acid derivatives. Solutions are unstable and should be fresh-prepared.
S3980 Pyridoxine Pyridoxine (Pyridoxol, Vitamin B6, Gravidox), also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement. It is a cofactor for both glutamic acid decarboxylase and GABA transaminase.
S3967 Flavone Flavone (2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron), a class of flavonoids, mainly found in spices and red or purple plant foods with antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders etc.
S3975 Protocatechuic acid Protocatechuic acid (PCA, 3,4-Dihydroxybenzoic acid, Protocatechuate), a dihydroxybenzoic acid, is a type of widely distributed naturally occurring phenolic acid.
S3976 Acetylvanillin Acetylvanillin (Acetovanillin, Vanillin acetate, 4-Acetoxy-3-methoxybenzaldehyde, 4-Formyl-2-methoxyphenyl acetate) is found in pulses and is a flavouring material.
S3977 (-)-Borneol (-)-Borneol (L-Borneol), one of enantiomers of borneol, has a camphoraceous and evident woody odor.
S4821 Glycine Glycine (2-Aminoacetic acid, Aminoacetic acid, Glycocoll) is a non-essential, non-polar, non-optical, glucogenic amino acid that is primarily found in gelatin and silk fibroin. It is involved in the body's production of DNA, phospholipids and collagen, and in release of energy.
S4826 Aluminium hydroxide Aluminium hydroxide (Aluminic), found in nature as the mineral gibbsite, is amphoteric (i.e., it has both basic and acidic properties). It is used to treat symptoms of increased stomach acid, such as heartburn, upset stomach, sour stomach, or acid indigestion; also reduce phosphate levels in people with certain kidney conditions.
S3986 L-Arabinose L-Arabinose (L-Ara) 是一种植物糖,不存在于动物中。它是细胞壁的成分之一,可能用于天然药物的合成。
S3987 L-Tryptophan L-tryprophan是必需氨基酸,是一种天然的情绪调节剂,为婴幼儿正常生长、成人氮平衡所必需。
S3989 L-​Histidine L-​Histidine (Glyoxaline-5-alanine) 是一种α-氨基酸,是人类生长和组织修复所必需,被用于蛋白质的生物合成。
S3990 Trans-Anethole Trans-anethole (4-Propenylanisole)是苯丙烯衍生物,存在于多种香精油、包括茴香油中。它具有神经调节、抗焦虑、抗氧化、抗真菌、抗炎症和免疫调节活性。
S4972 Choline Glycerophosphate Choline Glycerophosphate (Glycerophosphorylcholine) 是胆碱衍生物,是胞浆中两种主要的胆碱储存形式之一。
S4981 Cyclogalegenol Cyclogalegenol (Astramembrangenin, Cyclosieversigenin) 是astragaloside A的糖苷配基衍生物,存在于多种紫云英属物种中,可能可激活端粒酶
S4982 2,2':5',2''-Terthiophene 2,2':5',2''-Terthiophene是来源于金盏花的天然产物,具有受紫外线增强的抗菌活性。
S4983 Sorbic acid Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S2323 Methyl-Hesperidin Methyl-Hesperidin 是一种在柑橘类水果中广泛存在的黄酮苷(黄酮)(C28H34O15),其苷元形式被称为橙皮素。
S5090 4-Isopropylbenzyl Alcohol 4-Isopropylbenzyl Alcohol (Cumic alcohol, Cuminyl alcohol, Cuminic alcohol),分离自赤桉,是一种具有杀虫作用的化合物。
S5091 Geranyl acetate Geranyl acetate (Geraniol acetate, Geranyl ethanoate) 是一种天然有机化合物,主要用作面霜和肥皂的香料或是调味成分。
S5089 4-Isopropylbenzaldehyde 4-Isopropylbenzaldehyde (Cuminaldehyde, Cuminic aldehyde, Cuminal),一种天然有机化合物,是一种药物中间体,具有宜人的香味,有助于香精油中的香气。
S5086 p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde),茴芹种子提取物,具有抗真菌活性,对很多酵母和实验室培养基、果泥和果汁中的霉菌菌株具有活性。
S5220 D-Pantethine Pantethine (Bis-pantethine, Pantetina, Pantomin, Pantosin)是一种天然产物,在体内由泛酸(维生素B5)通过半胱胺的加入合成,被用作一种食品添加剂,降低血胆固醇和三酸甘油脂。
S3982 Batyl alcohol Batyl alcohol (Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
S5156 4-Methoxysalicylaldehyde 4-Methoxysalicylaldehyde (2-Hydroxy-4-methoxybenzaldehyde), a naturally occurring product, has a range of industrial applications in the preparation of organic compounds, drugs and therapeutic agents.
S5154 Tetrahydropiperine Tetrahydropiperine (Cosmoperine), 来源于胡椒碱,可用于治疗惊厥,癫痫,缓解疼痛和昆虫防治。
S5155 Raffinose Raffinose (Melitose, Melitriose) is a complex carbohydrate, a trisaccharide composed of galactose, fructose, and glucose. It can be broken apart into galactose and sucrose via the enzyme alpha-galactosidase.
S5226 L-carnosine L-carnosine (Karnozin) is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.
S3970 Vindoline Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly.
S5570 Arachidic acid Arachidic acid (eicosanoic acid, Icosanoic Acid) is a natural saturated fatty acid used for the production of detergents, photographic materials and lubricants.
S3971 Fusidine Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
S5562 2-Hydroxybenzyl alcohol 2-Hydroxybenzyl alcohol (Salicyl alcohol, Salicain, Diathesin, Saligenin, Saligenol, o-Methylolphenol, α,2-Toluenediol), which can be found in a number of food items such as red huckleberry, rye, jerusalem artichoke, and ceylon cinnamon, is precursor of salicylic acid and is formed from salicin by enzymatic hydrolysis by Salicyl-alcohol beta-D-glucosyltransferase or by acid hydrolysis.
S5335 Corey Lactone Diol Corey Lactone Diol is a pharmaceutical intermediate.
S5336 Hecogenin Hecogenin (Hocogenin), a steroid saponin isolated from Agave sisalana, is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM.
S5338 L(-)-Sorbose L(-)-Sorbose (L(-)-Sorbopyranose) is a ketose sugar that is commonly used in the commercial synthesis of ascorbic acid.
S5343 Vanillic acid Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a flavoring agent which is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects.
S5337 Rauwolscine hydrochloride Rauwolscine hydrochloride (Isoyohimbine, α-Yohimbine, corynanthidine) is the hydrochloride salt form of Rauwolscine, a specific and potent α2 antagonist with Ki of 12 nM.
S5342 Dihydrojasmone Dihydrojasmone, belonging to the family of ketones, is an aroma compound for perfumery uses.
S5339 4-Allylanisole 4-Allylanisole (Estragole, p-Allylanisole, Methyl chavicol) is a natural organic compound that is a component of various trees and plants. It is used in the preparation of fragrances.
S3785 Notoginsenoside R1 Notoginsenoside R1 (Sanchinoside R1) is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways.
S5345 Nerolidol Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.
S5347 2-Phenylethylamine 2-Phenylethylamine (β-Phenylethylamine, benzeneethanamine, β-aminoethylbenzene) is a natural monoamine alkaloid that functions as a monoaminergic neuromodulator or a neurotransmitter in the human central nervous system.
S5348 Pherocon (4-(4-Acetoxyphenyl)-2-butanone) Pherocon (4-(4-Acetoxyphenyl)-2-butanone, 4-(p-Acetoxyphenyl)-2-butanone, 4--(3-Oxobutyl)phenyl acetate) is a standard melon fly attractant for detection programs.
S5440 Berberine Sulfate Berberine sulfate (Umbellatine), an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
S3772 5-Hydroxymethylfurfural 5-Hydroxymethylfurfural (5-HMF) is an important bio-sourced intermediate, formed from carbohydrates such as glucose or fructose and used for production of fuels and chemical intermediates.
S3792 Guggulsterone E&Z Guggulsterone is one of the active constituent of Commiphora mukul. It occurs in two isomeric forms, namely Z-GS and E-GS. Guggulsterone act as antagonist ligands for the bile acid receptor, farnesoid X receptor, and as active ingredients responsible for the hypolipidemic activity.
S5407 Squalane Squalane (Perhydrosqualene, Dodecahydrosqualene) is a naturally occuring lipid in both plants and animals. It is usually used as an emollient and moisturizer in cosmetics manufacturing.
S3805 Stevioside Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana (Bertoni) Bertoni.
S5583 Cinnamyl acetate Cinnamyl acetate (3-Phenylallyl acetate) is a naturally occuring compound used as a flavouring agent.
S5584 Citronellol Citronellol (Dihydrogeraniol, (±)-β-Citronellol), a constituent of rose and geranium oils, is used in perfumes and insect repellents. Citronellol can cause necrotic apoptosis of NCI-H1299 cells by up-regulating TNF-α, RIP1 / RIP3 activities, and down-regulating caspase-3 / caspase-8 activities. Citronellol also results in a biphasic increase in ROS production at 1 h and at 12 h in NCI-H1299 cells.
S5419 1,4-Cineole 1,4-Cineole (Isocineole) is a flavor constituent of Citrus aurantifolia and Piper cubeba.
S3894 Cycloastragenol Cycloastragenol (CAG, TA-65, Cyclogalegigenin, Astramembrangenin) is a saponin comprising a group of oil glucosides naturally present in a number of plants. It is a potent telomerase activator in neuronal cells.
S5380 7-Hydroxyflavone 7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2. It also has excellent antioxidant properties and great potential to be applied as medicines.
S3895 Sophoridine Sophoridine (5-Epidihydrosophocarpine, Dihydro-5-episophocarpine), a natural product obtained from medicinal plants, has a variety of pharmacological effects, including anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems.
S5381 Behenic Acid Behenic Acid (docosanoic acid) is a long-chain saturated fatty acid that exists naturally as a triglyceride in canola. It act as a lubricant that helps restore the skin's natural oils and improve overall levels of hydration.
S3849 D-Galactose D-Galactose (D-Galactopyranose, D-(+)-Galactose) is an aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.
S3850 Glucosamine sulfate Glucosamine sulfate (D-Glucosaminesulfate, D-Glucosamine sulphate) is a dietary supplement commonly used in the treatment of osteoarthritis. It is a type of glycosaminoglycan, which is a naturally occurring major component of joint cartilage and joint fluid.
S3851 Camphor Camphor (2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa) is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora and used topically as a skin antipruritic and as an anti-infective agent.
S3852 L-Theanine L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
S3854 Tetrahydropalmatine hydrochloride Tetrahydropalmatine (THP, Gindarine, 1-Tetrahydropalmitine) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo), but also in other plants such as Stephania rotunda. It is a potent muscle relaxant.
S3855 Ethyl ferulate Ethyl ferulate (Ferulic acid ethyl ester) is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiproliferative activities.
S3856 Allantoin Allantoin (Glyoxyldiureide, 5-Ureidohydantoin), produced from uric acid, is a major metabolic intermediate in most organisms including animals, plants and bacteria.
S3857 4-Hydroxybenzyl alcohol 4-hydroxybenzyl alcohol (P-Methylolphenol, 4-Methylolphenol), an important phenolic constituent of Gastrodia elata Blume (GEB), has been shown to have many beneficial effects in different animal models of neurological disorders, such as, headaches, convulsive behavior, dizziness, and vertigo.
S3858 Lawsone Lawsone (Hennotannic acid, 2-hydroxy-1,4-naphthoquinone) is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).
S3859 Vanillyl Alcohol Vanillyl alcohol (4-Hydroxy-3-methoxybenzyl alcohol, Vanillin alcohol, Vanillic alcohol, 3-Methoxy-4-hydroxybenzyl alcohol), derived from vanillin, is used to flavor food.
S5618 Hippuric acid Hippuric Acid (2-Benzamidoacetic acid, Benzoylglycine) is an acyl glycine produced by the conjugation of benzoic acid and glycine, found as a normal component in urine as a metabolite of aromatic compounds from food.
S3862 Gallic acid trimethyl ether Gallic acid trimethyl ether (Eudesmic acid, Tri-O-methylgallic acid, Benzoic acid, 3,4,5-Trimethoxybenzoic acid) is an O-methylated trihydroxybenzoic acid that is found in olive.
S3864 Dulcitol Dulcitol (Galactitol, D-Galactitol, Dulcose) is a naturally occurring product of plants obtained following reduction of galactose.
S3865 Taurochenodeoxycholic acid Taurochenodeoxycholic acid (Taurochenodeoxycholic acid (Taurochenodeoxycholate, TCDCA, Chenodeoxycholyltaurine)), a bile acid formed in the liver of most species, is used as a cholagogue and choleretic.
S3866 Galanthamine Galanthamine (Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is a phenanthrene alkaloid and a reversible, competitive acetylcholinesterase inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. It is studied as a treatment for Alzheimer's disease and other central nervous system disorders.
S3868 Harmine Harmine (Telepathine)是属于β-咔啉家族化合物的一种荧光harmala生物碱,是一种高细胞渗透性的 DYRK1A 的激酶口袋结合ATP的竞争性抑制剂,与DYRK2结合IC50值高约60倍。Harmine 还可以抑制 monoamine oxidases (MAOs), PPARγcdc-like kinases (CLKs)。Harmine 抑制 5-HT2A serotonin receptor 的Ki值为397 nM。
S3870 D-Pinitol D-pinitol (Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol) is a naturally occurring compound derived from soy and has significant pharmacological activitites such as inhibition of the T-helpercell-1 response, antiviral, larvicidal, antiinflammatory, antihyperlipidemic, cardioprotective, inhibition of ovalbumin-induced airway inflammation and antioxidant.
S3872 Guaiacol Guaiacol (O-methoxyphenol, 2-hydroxyanisole, O-methylcatechol) is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a precursor to various flavorants, such as eugenoland vanillin. Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.
S5461 Cimicifugoside Cimicifugoside is a triterpenoid originating from the rhizomes of Cimicifuga simplex, and acts to inhibit the subcellular transport of nucleosides.
S5454 Saikosaponin D Saikosaponin D, a calcium mobilizing agent (SERCA inhibitor), is a type of Saponin derivative, which is a component extracted from Bupleurum falactum. Saikosaponin D has anti-cancer activities.
S3981 Sinapinic Acid Sinapinic acid (Sinapic acid) 是一种天然的小羟基肉桂酸,属于苯基丙烷类,通常在MALDI质谱中用作基质。Sinapinic acid (Sinapic acid) 作为 HDAC 的抑制剂,IC50为2.27 mM,并且还抑制 ACE-1 活性。
S3983 Caryophyllene oxide Caryophyllene oxide是存在于多种植物精油中的氧化萜类化合物,在食物、药物和化妆品中被用作防腐剂,具有消炎、抗癌和增强皮肤渗透活性。
S3984 Nordihydroguaiaretic acid (NDGA) Nordihydroguaiaretic acid (NDGA)是一种天然存在的酚类防老剂。它是公认的脂肪氧合酶 lipoxygenase抑制剂,具有抗氧化、清除自由基的活性。Nordihydroguaiaretic acid (NDGA) 是一种具有细胞毒性的 insulin-like growth factor-I receptor (IGF-1R)/HER2 的抑制剂,可诱导细胞凋亡。Nordihydroguaiaretic acid (NDGA) 可抑制 p300 并激活自噬。Nordihydroguaiaretic acid (NDGA) 可保护细胞免于铁死亡。
S5105 Proanthocyanidins Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.
S5148 2-Methylenebutyrolactone 2-Methylenebutyrolactone (Tulipalin A, MBL, α-methylene-γ-butyrolactone),也被称作α-methylene-γ-butyrolactone (MBL) 或Tulipalin A,是一种倍半萜内酯,被认为是最常见乙烯基单体甲基丙烯酸甲酯(MMA)的环状类似物。
S5150 Phytosterols Phytosterols,也被称作植物甾醇或醇酯,存在于植物中,结构类似于人体中胆固醇。
S5151 Gipsoside Gipsoside是一种来自gypsophila paniculata L.的三萜皂苷。
S3956 Tetramethylpyrazine Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S3957 Gamma-Oryzanol Gamma-oryzanol (GO), a nutriactive phytochemical naturally occurring in crude rice bran oil, is an antioxidant compound used to treat hyperlipidemia, disorders of menopause and to increase the muscle mass.
S3959 (+)-Borneol (+)-Borneol is one of enantiomers of borneol which is a valuable medical material, senior aromatic spice, and chemical material and has been used in food and also folk medicine.
S3962 Dihydroactinidiolide Dihydroactinidiolide is known to be a bioactive molecule in animals. It is a component of pheromones in insects, such as red fire ants and in mammals such as the Cat and the Red Fox.
S3963 DL-Glutamine DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.
S3968 Histamine Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.
S5120 Elemicin Elemicin (3,4,5-trimethoxyallylbenzene) is a constituent of the oleoresin and the essential oil of Canarium luzonicum.
S5121 Phytol Phytol (Trans-Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.
S5139 Methyl Dihydrojasmonate Methyl dihydrojasmonate (Hedione, Kharismal) is a flavouring ingredien with the smell vaguely similar to jasmin.
S5138 Citral Citral (Geranialdehyde) is an α,β-unsaturated aldehyde present in the oils of several plants. It is an aroma compound used in perfumery for its citrus effect and is also used as a flavor and for fortifying lemon oil.
S4754 Betulin Betulin (BE, betulinol, betuline, betulinic alcohol), also known as betulinol, betuline, or betulinic alcohol, is a pentacyclic lupane-type triterpenoid naturally distributed in many plants and displays a broad spectrum of biological and pharmacological properties such as anticancer and chemopreventive activity.
S3955 Uric Acid Uric Acid (2,6,8-Trioxypurine, 2,6,8-Trihydroxypurine, 2,6,8-Trioxopurine), a normal component of urine, is a product of the metabolic breakdown of purine nucleotides.
S4766 Gibberellic acid Gibberellic acid (Gibberellin, Gibberellin A3, GA3, GA), a plant hormone stimulating plant growth and development, is a tetracyclic di-terpenoid compound.
S3948 Spermine Spermine (4,9-Diaza-1,12-dodecanediamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.
S2283 Cinchonine(LA40221) Cinchonine (LA40221)是一种生物碱,是cinchonidine的立体异构体和假对映异构体。.
S3654 Tauroursodeoxycholic Acid (TUDCA) Tauroursodeoxycholic acid (TUDCA)是乌索脱氧胆酸的牛磺酸共轭产物,在多种神经退行性疾病,如阿尔茨海默病、帕金森疾病和亨廷顿疾病中,可作为线粒体稳定剂和抗凋亡试剂。
S3752 isoleucine Isoleucine (Ile) is a non-polar, uncharged (at physiological pH), aliphatic amino acid that is used in the biosynthesis of proteins.
S3753 L-Leucine Leucine ((S)-Leucine, Leu) is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing.
S3653 Spermidine trihydrochloride Spermidine (4-Azaoctamethylenediamine) 是一种从腐胺和dcSAM中,通过亚精胺合成酶合成的天然聚胺。它是新型的自噬诱导剂,负向调控N-methyl-d-aspartate (NMDA)
S3754 4-Hydroxybenzoic acid 4-Hydroxybenzoic acid (p-hydroxybenzoic acid, PHBA, para-Hydroxybenzoic acid, 4-hydroxybenzoate), also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. It is the most widely distributed aromatic organic acid in the vegetable kingdom.
S3893 Bornyl acetate Bornyl acetate (Isobornyl, Bornyl acetic ether, 2-Camphanol), the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic.
S3758 Sinomenine hydrochloride Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.
S3755 Betaine Betaine (trimethylglycine, glycine betaine, lycine, oxyneurine), a methyl derivative of glycine first isolated from sugar beets, has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscle gain and fat loss because of its abilities to promote protein synthesis in the body.
S3757 2'-Deoxyinosine 2’-Deoxyinosine (Guanine deoxyriboside, Deoxyinosine) is the nucleoside form of hypoxanthine. It is a product of DNA damage that is formed from 2’-deoxyadenosine by adenosine deaminase or reactive nitrogen species. 2’-deoxyinosine enhances apoptosis induced by 5-fluorouracil in HT-29 and SW620 cancer cells.
S3770 Sodium Aescinate Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic. Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.
S3681 Vitamin E Acetate Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant.
S3853 Perillyl alcohol Perillyl alcohol (Perilla alcohol, Isocarveol) is a monoterpene isolated from the essential oils of lavendin, peppermint, spearmint, cherries, celery seeds, and several other plants.
S3871 Muscone Muscone (3-Methylcyclopentadecanone, Methylexaltone)是一种增香成分,一种有机化合物,是麝香气味的主要来源,也是一种有效的消炎剂。Muscone 可显著地下调LPDM诱导的炎症细胞因子水平,并抑制BMDM中 NF-κBNLRP3 炎性小体的活化。Muscone 还可以显著地降低炎性细胞因子inflammatory cytokines (IL-1β, TNF-α, IL-6) 的水平。
S3762 Methylnonylketone Methylnonylketone (2-Undecanone, IBI-246), also known as 2-Undecanone and IBI-246, is a natural non-toxic insect repellant compound.
S3789 Tiglic acid Tiglic acid (Cevadic acid, Sabadillic acid, Tiglinic acid) is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. It is used in making perfumes and flavoring agents.
S3791 Succinic acid Succinic acid (1,4-Butandioic Acid, 1,2-Ethanedicarboxylic acid, Amber acid, Asuccin, Butanedioic acid) is a crystalline organic acid which occurs in living tissue as an intermediate in glucose metabolism.
S3793 Phytic acid Phytic acid (Inositol polyphosphate, Inositol hexakisphosphate) is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining.
S3794 Palmitic acid Palmitic acid (Hexadecanoic acid, Cetylic acid) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.
S3795 Phloretic acid Phloretic acid (Desaminotyrosine, Hydro-p-coumaric acid, Phloretate, 3-(4-Hydroxyphenyl)propanoic acid) is a naturally occurring phenolic compound which can be produced by the hydrogenation of p-coumaric acid or synthesized from phloretin, a by-product of apple tree leaves.
S3796 Rebaudioside A Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste.
S3797 Helicide Helicide (4-formylphenyl-O-β-d-allopyranoside), a main active constituent from seeds of the Chinese herb Helicia nilagirica, has been reported to exert a sedative, analgesic and hypnotic effect, and is used clinically to treat neurasthenic syndrome, vascular headaches and trigeminal neuralgia.
S3799 Gentisic acid Gentisic acid (2,5-dihydroxybenzoic acid, 5-Hydroxysalicylic acid, Hydroquinonecarboxylic acid, DHB), an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.
S3802 Trigonelline Hydrochloride Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.
S3803 Angelic acid Angelic acid ((Z)-2-Methylbut-2-enoic acid) is a monocarboxylic unsaturated organic acid that is mostly found in the plants of the family Apiaceae.
S3812 Monocrotaline Monocrotaline (MCT, Crotaline) is an 11-membered macrocyclic pyrrolizidine alkaloid (PA) that causes a pulmonary vascular syndrome in rats characterized by proliferative pulmonary vasculitis, pulmonary hypertension, and cor pulmonale.
S3886 Quinic acid Quinic acid (Chinic acid, Kinic acid) is a crystalline acid obtained from cinchona bark, coffee beans, and other plant products and made synthetically by hydrolysis of chlorogenic acid.
S3887 α-L-Rhamnose monohydrate α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.
S3742 Cholic acid Cholic acid是一种天然胆汁酸,在水中不可溶,用来治疗具有合成胆汁酸遗传缺陷的患者。
S3679 Flavanone Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one)具有较强的抗氧化和清除自由基活性,可能可减少某些慢性疾病的风险、阻滞一些心血管疾病以及某些癌症。Flavanones还具有抗病毒、抗菌、消炎活性,对毛细管脆性有一定改善效果、抑制人血小板凝聚、抗溃疡、降低过敏反应。
S4808 L-Cystine L-Cystine is the oxidized dimer form of the amino acid L-cysteine which is a non-essential amino acid of the human body. It is required for wound healing and formation of epithelial tissue.
S4811 VitaMin U Vitamin U (Methylmethioninesulfonium Chloride, Cabagin-U, Smethylmethionine) is a vitamin found in green vegetables. It is used in the treatment of peptic ulcers, colitis, and gastritis and has an effect on secretory, acid-forming, and enzymatic functions of the intestinal tract.
S5107 Riboflavin phosphate sodium Riboflavin phosphate sodium (Flavin mononucleotide, riboflavin-5'-phosphate, FMN, Vitamin B2 Phosphate Sodium Salt) is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as prosthetic group of various oxidoreductases including NADH dehydrogenase as well as cofactor in biological blue-light photo receptors.
S5108 Tylosin Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.
S3626 Sesamol Sesamol (1,3-Benzodioxol-5-ol, 3,4-Methylenedioxyphenol)是一种天然有机化合物,是油中主要的抗氧化成分,具有化学防癌、抗诱变剂和抗毒肝素活性。它能诱导癌细胞和心血管细胞凋亡。
S3625 Tyramine Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) 是一种来源于氨基酸酪氨酸的天然微量胺,是一种儿茶酚胺释放试剂。
S3624 Quinolinic acid Quinolinic Acid (pyridine-2,3-dicarboxylic acid, QUIN)是犬尿氨酸途径中的具有神经活性的代谢物,是N-methyl-D-aspartate (NMDA)受体的激动剂。
S3629 Syringic acid Syringic acid (NSC 2129, SYRA) 是一种有效的抗氧化中草药,是一种新兴的营养食品。它具有潜在的抗血管生成、抗糖基化、抗高血糖、神经保护和增强记忆的活性。
S3630 Methyl Vanillate Methyl Vanillate是枳椇子成分之一,在体外能激活Wnt/β-catenin信号通路并诱导成骨分化。
S5362 Citicoline Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a naturally occurring compound that acts as nutrient with a broad spectrum of benefits for conditions associated with symptoms of neurological dysfunction. As an endogenous compound, it is also an essential intermediate in the synthesis of cell membrane phospholipids and its formation is the rate-limiting step in phosphatidylcholine synthesis.
S5368 Lactitol Lactitol is a versatile, reduced calorie sweetener derived from natural milk sugar, used in a wide variety of sweetening applications.
S4955 Acetosyringone Acetosyringone (Acetosyringenin) is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions.
S5571 L-Asparagine L-Asparagine (2-Aminosuccinamic acid, alpha-aminosuccinamic acid) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
S5594 α-Terpineol α-Terpineol, a natural monoterpene, is the major component of essential oils of several species of aromatic plants such as Origanium vulgare L. and Ocimum canum Sims which are widely used for medicinal purposes. It is widely used in the manufacturing of cosmetics, soaps, perfumes, antiseptic agents and is considered one of the most frequently used fragrance compounds.
S5576 Benzyl acetate Benzyl acetate (Acetic acid benzyl ester, Benzyl ethanoate, Phenylmethyl), usually found in alcoholic beverages, is a flavouring agent.
S5585 Citronellal Citronellal (Rhodinal, 2,3-Dihydrocitral), a monoterpenoid found in oil of citronella, lemon, and lemon grass, has insect repellent properties and is used in perfumes.
S3675 Umbelliferone Umbelliferone (7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone) is a 7-hydroxycoumarin that is a pharmacologically active agent. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with anti-inflammatory, anti-hyperglycaemic, molluscicidal and anti-tumor activities.
S3677 Cinnamic acid Cinnamic acid (Benzenepropenoic acid, Isocinnamic acid, trans-Cinnamic acid, Phenylacrylic acid), a naturally occurring aromatic fatty acid of low toxicity, induces cytostasis and a reversal of malignant properties of human tumor cells in vitro.
S3661 2-Methoxy-1,4-naphthoquinone 2-Methoxy-1,4-naphthoquinone, isolated from the leaves of Impatiens glandulifera, specifically suppressed the expression of PKC βI, δ, and ζ in a concentration-dependent manner in Raji cells.
S3652 3-Nitropropionic acid (3-NP) 3-Nitropropionic acid (3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.
S5513 Calcium D-saccharate tetrahydrate Calcium D-saccharate tetrahydrate (Calcium Saccharate, D-Saccharic acid calcium salt, D-Glucaric acid calcium salt) is the calcium salt form of glucaric acid, a natural substance found in many fruits and vegetables, with potential anti-cancer property.
S5518 D-Glucose 6-phosphate disodium salt D-Glucose 6-phosphate disodium salt is the disodium salt form of D-Glucose 6-phosphate, a common form of glucose within the cell, participating in two major metabolic pathways: glycolysis and the pentose phosphate pathway. It can be coverted to glycogen or starch for storage.
S2416 Chondroitin sulfate Chondroitin sulfate是一种硫酸化糖胺多糖(GAG),组成交替糖分包括乙酰半乳糖胺和葡萄糖醛酸。
S5327 Meisoindigo Meisoindigo (N-Methylisoindigotin, Methylisoindigotin, Dian III), a derivative of Indigo naturalis, is an active compound of a Chinese anti-leukemia medicine that has been effectively used in the treatment of chronic myelogenous leukemia (CML).
S5599 Sodium cholate Sodium cholate (NaCh) is the sodium salt of the naturally occurring cholic acid, a bile salt produced by the liver, with strong solubilization capacity of water-insoluble substances.
S5575 2-Benzoxazolinone 2-Benzoxazolinone (BOA, 2-Hydroxybenzoxazole), a well-known allelochemical with strong phytotoxicity, is a potential herbicidal candidate and probably functions via interfering with auxins or disrupting membrane integrity.
S5579 Chelidonic acid Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid) 是在几种植物中发现的次级代谢产物,对实验动物的过敏性疾病具有治疗潜力。Chelidonic acid 通过阻断HMC-1细胞中的 NF-κBcaspase-1 来抑制 IL-6 的产生。Chelidonic acid 也是 glutamate decarboxylase 的抑制剂,其Ki值为1.2 μM。
S5588 Creatine Creatine (Methylguanidoacetic acid) 是一种天然存在于脊椎动物中的含氮有机酸。Creatine 可以通过抑制 IFN-γ receptorsJAK2 的相互作用来抑制 JAK-STAT1 信号传递,以ATP非依赖性的方式促进三磷酸腺苷(ATP)的循环,从而抑制下游促炎基因表达。
S5614 (+)-Longifolene (+)-Longifolene is a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins.
S5595 3-Carene 3-Carene (Carene, Delta-3-Carene)是在从松树中提取的精油中的双环单萜。 3-Carene对 COX-2 过表达和LPS诱导的Raw264.7巨噬细胞迁移具有强大的药理作用。3-Carene被证明可显着刺激 alkaline phosphatase 的活性和表达 ,是成骨细胞分化的早期标志。
S5376 Decyl aldehyde Decyl aldehyde (Decanal, Capraldehyde, Decanaldehyde) is a naturally occuring organic compound that is used in fragrances and flavoring.
S5551 6-Paradol 6-Paradol is a minor constituent of ginger, mainly formed from 6-gingerol via 6-shogaol, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities.
S5379 Fenchyl Alcohol Fenchyl Alcohol is used as a flavoring agent to provide a pine, herbal, lemon, or floral taste to food and drink.
S5530 Geraniol Geraniol is a terpene alcohol occurring in the essential oils of several aromatic plants used in the flavour and fragrance industries. It also exhibits insecticidal and repellent properties and used as a natural pest control agent exhibiting low toxicity.
S5237 Dihydroartemisinic acid Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
S5516 Ellagic Acid hydrate Ellagic acid is a potent inhibitor of protein kinase CK2 with IC50s of 0.04, 2.9 and 3.5 μM for CK2, Lyn and PKA respectively. It shows potent antioxidant, anti-mutagenic and antidepressant properties.
S3612 Rosmarinic acid Rosmarinic acid (RA, Rosemary acid) 是一种天然的羟化化合物。它具有阻止补体结合、抑制脂肪氧合酶和环氧煤活性的功能,通过抑制NF-κB激活信号中IKK-β的活性、抑制CCL11和CCR3的表达。
S3609 Berbamine dihydrochloride Berbamine (BA, BBM) dihydrochloride 是一种从中草药黄芦木中分离而来的双苄基异喹啉类天然产物。它是bcr/abl的新型抑制剂,具有有效的抗白血病活性,是NF-κB的抑制剂。Berbamine (BA, BBM) dihydrochloride 通过靶向 Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) 抑制癌细胞的生长,并诱导人骨髓瘤细胞凋亡。
S5459 Aucubin Aucubin (Rhinanthin), an iridoid glycoside existing in medicinal plants, has been reported to show an anti-inflammatory activity by suppression of TNF-α production in murine macrophages.
S5471 Monotropein Monotropein, an iridoids glycoside isolated from the roots of Morinda officinalis How, has been demonstrated to exhibit anti-inflammatory activity.
S5452 Sanguinarine chloride Sanguinarine, a plant alkaloid, is a potent and specific protein phosphatase (PP) 2C inhibitor.
S5458 Verbascoside Verbascoside (Acteoside, Kusaginin), a phenylpropanoid glycoside from lemon verbena, has several biological properties such as anti-inflammatory, antimicrobial, antitumor, and antioxidant.
S5467 Asarinin Asarinin (Sesamin, Fagarol, Pseudocubebin, Episesamin, Eleutheroside B4), isolated as a racemate from the shrub Zanthoxylum alatum, is usually used as a dietary fat-reduction supplement.
S5455 Akebia saponin D Akebia saponin D (Asperosaponin VI), the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
S5553 Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S5529 Galangin Galangin (3,5,7-trihydroxyflavone; Norizalpinin), a naturally occuring flavonoid found in herbs, is a well-known antioxidant and also an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor.
S5453 Hyperoside Hyperoside (Hyperin, Quercetin 3-galactoside), a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.Hyperoside can inhibit activation of the NF-κB signaling pathway.
S5460 Vitexin-2-O-rhaMnoside Vitexin-2-O-rhamnoside (2''-O-Rhamnosylvitexin, Apigenin-8-C-glucoside) is one of the main components of flavonoid of the leaves of Crataegus pinnatifida Bge. var major N. E. Br. It has many biological and pharmacological activities, such as antioxidation and treating heart disease.
S5468 Kaempferol-3-O-glucorhamnoside Kaempferol 3-neohesperidoside (Kaempferol 3-neohesperidoside), isolated from the herbs of Delphinium grandiflorum L., has insulin-like properties in terms of glucose lowering.
S5465 Morroniside Morroniside, an iridoid glycoside, is the main active ingredient from Cornus officinalis Sieb. et Zucc. and Sambucus williamsii Hance. It has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption.
S5463 Curcurbitacin IIA Curcurbitacin IIA (Cucurbitacin Iia, CuIIa, Hemslecin A, Dihydrocucurbitacin Q1) 是从园果雪胆中分离得到的三萜烯,可诱导癌细胞凋亡。Cucurbitacin IIa 可降低癌细胞中生存素 survivin 的表达,降低磷酸化组蛋白 H3 的水平,增加裂解的 PARP 的水平。
S5469 Bavachin Bavachin (Corylifolin) is a phytoestrogen purified from natural herbal plants such as Psoralea corylifolia. It acts as a weak phytoestrogen by binding and activating the ER.
S5462 5-O-Methylvisammioside 5-O-Methylvisammioside is a naturally occuring product isolated from Saposhnikovia Divaricata and has analgesic, antipyretic, anti-inflammatory and anti-platelet aggregation effects.
S5451 Ferulic acid methyl ester Ferulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer.
S5456 Isobavachalcone Isobavachalcone (Corylifolinin), a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
S5512 Juglone Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone)是一种天然萘醌,存在于黑核桃等植物中,对多种植物具有中等的抗真菌活性和促生长作用。它有时可以用作除草剂,作为布料和油墨的染料,以及作为食品和化妆品的着色剂。在溶液中不稳定,请现配现用!
S3880 Schisantherin A Schisantherin A (Gomisin C, Schisanwilsonin H, Arisanschinin K)是一种五味子红素,具有止咳、镇静、消炎、抗骨质疏松、神经保护、增强认知和心脏保护活性。Schisantherin A 也可通过IκBα降解抑制p65-NF-κB向核内移位。
S3882 Brassinolide Brassinolide是来源于Brassica napus pollen的植物类脂醇,可促进细胞延长、细胞分裂,从而调节植物生长和发育。
S2376 Ammonium Glycyrrhizinate Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt)是来自Licorice root的一种独特产品,具有极高的甜味。Ammonium Glycyrrhizinate 是 HMGB1 的直接抑制剂,具有抗炎、抗肿瘤、抗糖尿病的作用。Ammonium Glycyrrhizinate 可抑制几种不相关的DNA和RNA病毒的生长和细胞病理。Ammonium Glycyrrhizinate 还可抑制 hepatic delta 4-5-reductase11 beta-hydroxysteroid dehydrogenase
S2291 Diosgenin Diosgenin 是一种类固醇皂甙元,为半合成孕激素的前体,在早期与口服避孕药一起使用。
S3776 Sophoricoside Sophoricoside (SOPH)是一种分离自槐花(豆科)的异黄酮,具有多种药理作用,如消炎、抗癌、抑制免疫力等效应。
S5249 Coptisine chloride Coptisine (Q-100696, NSC-119754)是一种分离自黄连的吲哚联啶生物碱,具有抗糖尿病、抗菌、抗病毒、抗肝癌和抗白血病效应。Coptisine chloride 也是一种有效的非竞争性 IDO 的抑制剂,对应的IC50值和Ki值分别为6.3 μM和5.8 μM。
S3879 Kaempferide Kaempferide (4'-Methylkaempferol, 4'-O-Methylkaempferol, Kaempferol 4'-methyl ether) 是一种从山柰根中提取的天然产物,具有多种生物活性,包括抗癌、抗炎、抗氧化、抗菌抗病毒等活性。
S5049 Thiocolchicoside Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) 是一种天然存在的配糖体,来源于嘉兰百合的花种中,具有抗炎和止痛活性,同时具有显著的惊厥作用。它也是GABAA receptor的拮抗剂。
S8279 Shikonin Shikonin是一种 Pyruvate kinase M2 (PKM2) 有效的、特异的抑制剂。它是紫草的主要成分,紫草是一种中草药,具有多种生物活性。在细胞荧光淬灭试验中,Shikonin也是TMEM16A氯离子通道的抑制剂。Shikonin 通过抑制 tumor necrosis factor-α (TNF-α) 发挥抗炎作用,并可通过抑制 proteasome 来阻止 nuclear factor-κB (NF-κB) 信号途径的激活。
S3822 Schisandrin A Schisandrin A (Sch A, Deoxyschizandrin, Wuweizisu A) is an active component of Schisandrae Fructus with liver-protective, antitumor, and antioxidant activities. It is an agonist of the adiponectin receptor 2 (AdipoR2) with the IC50 value of 3.5 μM.
S4738 Arctiin Arctiin (Arctigenin-4-Glucoside, NSC 315527) 是脂联素受体1的激动剂,具有抗肿瘤活性。
S3807 Dehydroandrographolide Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.
S8132 Deguelin Deguelin,一种从植物中分离出来的天然产物,是PI3K/Akt的抑制剂。
S3824 Quercitrin Quercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities.
S2383 Gastrodin Gastrodin (Gastrodine) 是一种多元酚,是4-羟基苄醇的葡糖苷。
S2387 Lappaconite HBr Lappaconite HBr是从Aconitum sinomontanum Nakai 提取的一种生物碱,具有抗炎作用。
S3910 4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S3832 Euphorbiasteroid Euphorbiasteroid (Euphorbia factor L1)是Euphorbia lathyris L.的成分之一,通过激活AMPK信号通路抑制3T3-L1细胞的脂肪形成,并通过促进Bcl-2/Bax信号通路诱导HL-60细胞凋亡。
S4884 Trans-Zeatin Trans-Zeatina ((E)-Zeatin) 是植物生长激素的成员之一,属于细胞分裂素,可调节细胞分裂、发育和营养加工。Trans-Zeatina ((E)-Zeatin) 可抑制UVB诱导的 MMP-1 表达,c-Jun 活化和 ERKJNK 磷酸化和 p38 MAP kinases (MAPKs) 呈剂量依赖性。
S2250 EGCG ((-)-Epigallocatechin Gallate) EGCG ((-)-Epigallocatechin Gallate)是从绿茶中分离的一种有效的抗氧化剂Polyphenol flavonoid。抑制telomeraseDNA methyltransferase, 阻滞EGF受体HER-2受体的激活,抑制脂肪酸合成酶以及谷氨酸脱氢酶的活性。
S2290 DHA (Dihydroartemisinin) DHA (Dihydroartemisinin)是一种Artemisinin 的半合成衍生物,从传统中药Artemisia annua分离而来的。Dihydroartemisinin 可通过抑制 NF-κB 激活来诱导自噬和凋亡。
S7409 Anisomycin Anisomycin (Flagecidin, Wuningmeisu C) 是一种从Streptomyces griseolus提取的抗菌性抗生素,抑制蛋白质合成,也是一种 JNK 激活剂。Anisomycin 可促进自噬与凋亡。
S2295 Emodin Emodin 是Rhubarb, Buckthorn 和 Japanese Knotweed (Fallopia japonica)中的一种泻药树脂,是6-甲基-1,3,8-三羟蒽醌.
S2320 Luteolin Luteolin (Luteoline, Luteolol, Digitoflavone)是一种非选择性的PDE抑制剂,作用于PDE1-5Ki分别为15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM和9.5 μM。
S3818 Tectoridin Tectoridin (Shekanin), an isoflavone isolated from flowers of Pueraria thunbergiana, has several pharmacological effects including anti-cancer, anti-inflammatory, antioxidant, and hepatoprotectivy.
S2302 Glycyrrhizin (NSC 167409) Glycyrrhizin (NSC 167409, Glycyrrhizic Acid)是一种直接的高迁移率族蛋白1(HMGB1)的抑制剂,抑制依赖于HMGB1的炎症分子表达和氧化应激反应。调节p38和p-JNK信号通路,而不影响p-ERK信号通路。同时也能抑制11 beta-hydroxysteroid dehydrogenase
S4603 Gallic acid Gallic acid (3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid)是一种在多种食物和草药中发现的有机酸,是有效的抗氧化剂。
S3841 Eleutheroside B Eleutheroside B (syringin, Syringoside, Lilacin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties.
S3845 Panaxadiol Panaxadiol (20(R)-Panaxadiol) is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. It inhibits Ca2+ channels, decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential.
S3847 Panaxatriol Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities.
S3848 Hydroxytyrosol Acetate Hydroxytyrosol acetate (HTy-Ac), an extra virgin olive oil (EVOO) polyphenol, exhibits antioxidant and anti-inflammatory effects.
S3778 Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S3912 Cephalotaxine Cephalotaxine is a naturally occurring alkaloid which is the structural motif of a number of compounds and has shown promising anti-cancer properties.
S3930 Liquiritin Liquiritin (LIQ, Liquiritoside, Liquiritigenin-4'-O-glucoside) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.
S4758 Crocin Crocin (Alpha-Crocin, Gardenia Yellow)是藏红花中的一种水溶性类胡萝卜色素,被用于调味品和着色食品中的香料。在传统中药中,被用作止痛剂或镇定剂。
S3874 Curcumenol Curcumenol, a sesquiterpene isolated from Curcuma zedoaria, is known to possess a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation.
S3877 Lysionotin Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.
S3809 Imperatorin Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.
S3892 Isopsoralen Isopsoralen (Angelicin), also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses.
S3908 4'-Demethylpodophyllotoxin 4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.
S3938 Bisdemethoxycurcumin (BDMC) Bisdemethoxycurcumin (BDMC)是一种天然纯在的姜黄素去甲氧基衍生物,具有多种生物活性,如消炎和抗癌活性。
S3890 Leonurine Leonurine, an active alkaloid extracted from Traditional Chinese Medicine Herba leonuri, exerts several biological effects, such as antidiabetic, cardiovascular, and bovine mastitis protection.
S3816 Dehydroevodiamine Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.
S5144 Neferine Neferine ((R)-1,2-Dimethoxyaporphine) 是 Nelumbo nucifera 的天然成分,具有抗肿瘤功效。Neferine 可诱导肾癌细胞凋亡。Neferine 通过激活肌肉细胞中的 Akt/mTOR 通路和 Nrf2 来防止自噬。Neferine 可抑制 NF-κB 的激活。Neferine具有多种治疗作用,例如抗糖尿病,抗衰老,抗微生物,抗血栓形成,抗心律不齐,抗炎甚至抗HIV。
S4761 Thymoquinone Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa with anti-inflammatory and anti-oxidant effects.
S3906 Astragalus polyphenols Astragalus polyphenols(2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside) is a wonderful immune enhancing herb that has strong anti-viral activity and produces extra interferon in the body. It contains rich polyphenol with various effects including antioxidant and antiinflammatory actions.
S3907 Bulleyaconi cine A Bulleyaconi cine A (Bulleyaconitine A, BLA) is an active ingredient of Aconitum bulleyanum plants and classified as an "aconitine-like" alkaloid. It is a potent use-dependent blocker for both Nav1.7 and Nav1.8 Na+ currents.
S3909 Catalpol Catalpol (Catalpinoside, Digitalis purpurea L), an iridoid glucoside contained richly in the roots of the small flowering plant species Rehmannia glutinosa Libosch, has been shown to have antioxidation, anti-inflammation, anti-apoptosis and other neuroprotective properties and plays a role in neuroprotection against hypoxic/ischemic injury, AD and PD in both in vivo and in vitro models.
S3922 (-)-epigallocatechin (-)-Epigallocatechin, widespread in plants, has been shown to exhibit anti-tumor, anti-cancer and anti-inflammatory functions.
S3923 Ginsenoside Rg1 Ginsenoside Rg1 (Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1)是人参的主要活性成分之一,被确定为原人参三醇型,对多种癌症具有药理作用,例如神经保护和抗肿瘤作用。Ginsenoside Rg1 可降低 cerebral Aβ 水平并减少 NF-κB 核转移。
S3924 Ginsenoside Rb1 Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.
S3925 (-)-Epicatechin gallate (-)-Epicatechin gallate (ECG) 是一种 cyclooxygenase-1 (COX-1) 的抑制剂,IC50值为7.5 μM。
S3926 Forsythin Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.
S2317 L-(+)-Rhamnose Monohydrate L-(+)-Rhamnose Monohydrate 是一种天然存在的脱氧糖。
S3901 Astragaloside IV Astragaloside IV (AST-IV, AS-IV) is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. AS-IV suppresses activation of p-Akt, p-mTOR, p-NF-κB and p-Erk1/2.
S3915 Gracillin Gracillin, a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica, has been reported to exert antitumor activity.
S3916 Macranthoidin B Macranthoidin B (Macranthoiside I) is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae.
S3920 7β-Hydroxylathyrol 7β-Hydroxylathyrol (7beta-Hydroxylathyrol, 7-Hydroxylathyrol) is natural occuring product extracted from the seeds of Euphorbia lathyris L.
S3921 Lathyrol Lathyrol is a natural product that is used for cancer treatment.
S3931 Ginsenoside Rd Ginsenoside Rd (Panaxoside Rd, Sanchinoside Rd), a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.
S3765 Picroside II Picroside II (6-Vanilloylcatalpol, Vanilloyl catalpol) is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
S3875 Alpinetin Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number of biological properties, such as antibacterial, antitumor and other important therapeutic activities.
S3878 Bavachinin Bavachinin (7-O-Methylbavachin) ia a novel natural pan-PPAR agonist from the fruit of the traditional Chinese glucose-lowering herb malaytea scurfpea. It shows stronger activities with PPAR-γ than with PPAR-α and PPAR-β/δ (EC50 = 0.74 μmol/l, 4.00 μmol/l and 8.07 μmol/l in 293T cells, respectively).
S3881 Scopoletin Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.
S3883 Protopine Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.
S3884 Jatrorrhizine Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
S3800 Lycorine hydrochloride Lycorine (Galanthidine, Amarylline, Narcissine, Licorine), a natural alkaloid extracted from the Amaryllidaceae plant family, has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. It is an HCV inhibitor with strong activity.
S3801 Sodium Lauryl Sulfoacetate Sodium Lauryl Sulfoacetate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
S3804 Alpha-Mangostin Alpha-mangostin is the main xanthone purified from mangosteen and has health promoting benefits including anti-bacterial, anti-inflammatory, anti-oxidant, anti-cancer and cardioprotective activities. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. Alpha-mangostin is also an agonist of human STING.
S3808 Mangiferin Mangiferin (Alpizarin, Chinomin, Hedysarid) is a bioactive compound that demonstrates many health perspectives and has been used to prepare medicinal and food supplements. Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50.
S3810 Scutellarin Scutellarin (Breviscapine, Breviscapin, Scutellarein-7-glucuronide)是从中草药黄芩Scutellaria baicalensis和灯盏细辛Erigeron breviscapus中提取的主要活性类黄酮,具有许多药理作用,例如抗氧化、抗肿瘤、抗病毒和抗炎活性。Scutellarin 可以下调HCC细胞中的 STAT3/Girdin/Akt 信号传导,并抑制破骨细胞中RANKL介导的 MAPKNF-κB 信号通路。
S3811 Ginsenoside Re Ginsenoside Re (Ginsenoside B2, Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc)是三七的提取物、人参中的主要人参皂苷,属于20(S)-原人参三醇组 (protopanaxatriol group)。它具有多种体外和体内作用,包括血管舒张作用,抗氧化剂,抗高血脂和血管生成作用。Ginsenoside Re 会降低 β-amyloid protein (Aβ) 并通过抑制 JNKNF-κB 起到抗炎的作用。
S3891 Vincamine Vincamine (Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan), an indole alkaloid found in the leaves of V. minor and C. roseus, is a peripheral vasodilator that increases blood flow to the brain.
S3813 Bakuchiol Bakuchiol ((S)-(+)-Bakuchiol) is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has anti-inflammatory and antimicrobial activities.
S3919 Hederacoside C Hederacoside C (HDC, Kalopanaxsaponin B) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.) and used to treat respiratory disorders.
S3837 Echinocystic acid Echinocystic acid (EA), a natural triterpone enriched in various herbs, displays a range of pharmacological activities including anti-inflammatory and antioxidant effects.
S3844 Rosavin Rosavin, a cinnamyl alcohol glycoside found in the plant Rhodiola rosea, possesses antidepressant and anxiolytic activities.
S3846 Eupatilin Eupatilin (NSC 122413), a major flavonoid from Artemisia plants, possesses various beneficial biological effects including anti-inflammation, anti-tumor, anti-cancer, anti-allergy, and anti-oxidation activity.
S3779 cis-Anethole Anethole ((Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole) has two isomers, the cis(Z) isomer being 15-38 times more toxic to animal than the trans(E) isomer. cis-Anethole is found in anise and Only a low level is permitted in flavours.
S3782 Neomangiferin Neomangiferin (Mangiferin 7-glucoside), a natural xanthone C-glycoside mainly obtained from the well-known traditional Chinese medicine rhizoma of Anemarrhena asphodeloides, exhibits antidiabetic activity and antiosteoporotic action.
S3783 Echinacoside Echinacoside, a natural polyphenolic compound, has various biological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative actions.
S3777 Gentiopicroside Gentiopicroside (GE, Gentiopicrin), a naturally occurring iridoid glycoside, inhibits CYP2A6 and CYP2E1 with IC50 values of 21.8μg/ml and 594μg/ml, respectively in human liver microsomes, and dose not inhibit CYP2C9, CYP2D6, CYP1A2 or CYP3A4 activities.
S3784 Obacunone (AI3-37934) Obacunone (AI3-37934, CCRIS 8657), a natural compound present in citrus fruits, has been demonstrated for various biological activities including anti-cancer and anti-inflammatory properties. It significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM; also a novel activator of Nrf2.
S3786 Glabridin Glabridin (Q-100692, KB-289522, LS-176045), one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory.
S3787 Picroside I Picroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
S3780 Secoisolariciresinol diglucoside Secoisolariciresinol diglucoside (SDG), a plant lignan isolated from flaxseed, has strong antioxidant activity, cardioprotective effects, reduces the blood levels of low-density lipoprotein cholesterol, and reduces the risk of hormone related cancer.
S3914 α-Hederin α-hederin is a water-soluble pentacyclic triterpenoid saponin which has shown hemolytic and apoptotic properties.
S3929 Liquiritigenin Liquiritigenin (4',7-Dihydroxyflavanone), the most active estrogenic compound from the root of Glycyrrhizae uralensis Fisch, selectively binds to ERβ with an IC50 value of 7.5 μM and activates multiple ER regulatory elements and native target genes with Erβ but not ERα.
S3932 Astilbin Astilbin (Isoastilbin, Neoastilbin, Neoisoastilbin, Taxifolin 3-O-rhamnoside), a flavonoid compound isolated from the rhizome of Smilax glabra Roxb, displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities.
S3764 Isoferulic Acid Isoferulic acid (Hesperetic acid, Hesperetate, Isoferulate), a major active ingredient of Cimicifuga heracleifolia, shows anti-inflammatory, antiviral, antioxidant, and antidiabetic properties.
S3766 Tanshinone IIA sulfonate sodium Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA isolated as the main pharmacologically active natural compound from a traditional Chinese herbal medicine, the dried root of Salvia miltiorrhiza Bunge known as Danshen. Sodium tanshinone IIA sulfonate (STS) is a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium tanshinone IIA sulfonate (STS) inhibits the activity of CYP3A4 and store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC).
S3771 Stachydrine Stachydrine (Proline betaine, L-stachydrine, Methyl hygrate betaine) is a quaternary ammonium derivative of proline that occurs widely in Medicago species. It is an osmoprotective compound found in urine. Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.
S3773 Tyrosol Tyrosol (4-Hydroxyphenylethanol, 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethanol) is an antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
S3775 Ligustrazine hydrochloride Ligustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S5101 Tabersonine hydrochloride Tabersonine, an ingredient extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1−42) aggregation and toxicity.
S2318 Lappaconitine Lappaconitine (LC) is a natural diterpenoid alkaloid (DTA), acting as a human heart sodium channel blocker and possessing a wide range of biological activities, including anti-arrhythmic, anti-inflammatory, antioxidative, anticancer, epileptiform etc.
S3815 Mogroside V Mogroside V is a natural cucurbitane glycoside which has a sweetening strength of 250 times that of sucrose and is derived from mature fruit of luo-han-guo (Siraitia grosvenorii, monk fruit).
S3819 Decursinol angelate Decursinol angelate is a cytotoxic and protein kinase C activating agent from the root of Angelica gigas.
S3820 Dehydroevodiamine hydrochloride Dehydroevodiamine (DHE), a major phytochemical in fruits of Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.
S3825 Glycitin Glycitin (Glycitein-7-β-O-glucoside), a natural isoflavone isolated from legumes, has antibacterial, antiviral and estrogenic activities and may exerts preventative effects on alcoholism, cardiovascular and cerebrovascular diseases and some types of cancer.
S3826 Hydroxytyrosol Hydroxytyrosol (3,4-dihydroxyphenylethanol) is one of the main phenolic components of olive oil with excellent antioxidant, antimicrobial and anticarcinogenic activities.
S3827 Royal jelly acid Royal jelly acid (10-Hydroxy-trans-2-decenoic acid, 10H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysaccharide (LPS)- and interferon (IFN)-γ-stimulated macrophage responses, inhibition of T-cell proliferation and anti-rheumatoid activity.
S3828 Orcinol glucoside Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.
S3829 Isoalantolactone Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.
S3834 Astaxanthin Astaxanthin (β-Carotene-4,4'-dione, Trans-Astaxanthin), a xanthophyll carotenoid, is a nutrient with unique cell membrane actions and diverse clinical benefits with excellent safety and tolerability.
S3835 Loganin Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
S3836 6-Gingerol 6-Gingerol is the active constituent of fresh ginger known to exhibit a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
S3838 Carnosic acid Carnosic acid (Salvin) is a phenolic diterpene, endowed with antioxidative and antimicrobial properties. It is increasingly used within food, nutritional health and cosmetics industries.
S3840 Baohuoside I Baohuoside I (Icariside II) is a flavonoid isolated from Epimedium koreanum Nakai with anti-inflammatory and anti-cancer activities. It may exert cytotoxic effect via the ROS/MAPK pathway.
S3842 Isoquercitrin Isoquercitrin (Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside), a flavonoid compound with anticancer activity isolated from Bidens bipinnata L, is an inhibitor of Wnt/β-catenin that acts downstream of the β-catenin nuclear translocation.
S3833 Amentoflavone Amentoflavone (Didemethyl Ginkgetin) is a biflavonoid originally isolated from Selaginella with antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective activities.
S3943 Lycopene Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. It is a natural antioxidant.
S3960 Higenamine hydrochloride Higenamine (Norcoclaurine, (+-)-Demethylcoclaurine), also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants.
S3941 Pinocembrin Pinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone)是制药工业中多功能黄酮类分子,它具有很多药学活性,如抗菌、消炎、抗氧化和抗癌活性。
S5104 Tea polyphenol Tea polyphenols are chemical compounds such as flavanoids and tannins found naturally in tea. Several biological properties have been associated to tea polyphenols (TP), including antioxidant, anti-carcinogenic and antimicrobial activities.
S3939 4'-Methoxyresveratrol 4-Methoxyresveratrol is a stibenoid found in the Chinese herb Gnetum cleistostachyum. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.
S3940 3'-Hydroxypterostilbene 3'-Hydroxypterostilbene (3'-HPT)是苦马豆和紫檀木心中的活性成分之一,可能对治疗不同类型的恶性血液肿瘤有效。3'-Hydroxypterostilbene 可通过诱导凋亡和自噬,从而有效地抑制人结肠癌细胞的生长,对COLO 205,HCT-116和HT-29 cells的IC50值分别为9.0 µM、40.2 µM和70.9 µM。3'-Hydroxypterostilbene 会抑制 PI3K/Akt/mTOR 信号通路中的p70S6K 和 p38MAPK信号通路,而激活ERK1/2, JNK1/2 信号通路。
S3614 Lupeol Lupeol (Clerodol, Monogynol B, Fagarasterol, Farganasterol) 是一种显著的白桦脂酸型三萜烯,存在于植物、真菌和动物中,具有抗癌、抗原生动物、化学预防、消炎作用。
S3747 Levothyroxine (L-Thyroxine) sodium Levothyroxine (L-T4, L-Thyroxine) 是源于甲状腺的主要激素,是甲状腺激素受体α和β的激动剂。
S3668 Thymopentin Thymopentin (TP5) has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells.
S3608 Demethylzeylasteral (T-96) Demethylzeylasteral (T-96)是从Tripterygium wilfordii Hook F.中分离出的活性成分,能够抑制UDP-glucuronosyltransferase (UGT)的亚型UGT1A6UGT2B7,具有免疫抑制活性。
S3610 Cordycepin Cordycepin (3'-Deoxyadenosine) is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities.
S3613 Scoparone Scoparone (6,7-dimethoxycoumarin, Aesculetin dimethyl ether, 6,7-Dimethylesculetin, Escoparone)是一种天然的有机化合物,是从中草药猪毛蒿中提取而来,具有抗凝、降血脂、抗氧化和抗炎作用。
S3615 Dehydrocostus Lactone Dehydrocostus lactone (DHE)是一种天然的倍半萜内酯,抑制IKKβ活性、IκBα的磷酸化和降解、共激活子p300的招募、p50/p65 NF-κB的核转位及它们结合于COX2启动子上的能力。DHE具有抗炎、抗溃疡、抗肿瘤作用和免疫调节活性。
S3616 Asiaticoside Asiaticoside (Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol) 是Centella asiatica(积雪草)中的主要活性成分,通过抑制紫外线A诱导的ROS生成、阻止紫外线A依赖性的光老化。它还能通过MITF减少DNA结合。
S3606 Fangchinoline Fangchinoline是双苄基异喹啉类生物碱,是HIV-1的新型抑制剂,具有缓解疼痛、降低血压和抗菌活性。
S4752 Corticosterone Corticosterone是主要的压力激素,一种肾上腺皮质类固醇,具有作为盐皮质激素和糖皮质激素的活性。
S8291 Atractylenolide I Atractylenolide I 是A. macrocephala根茎的主要类倍半萜烯类化合物。具有广谱的药理活性,如抗炎、促消化、抗氧化作用。
S4742 Rebaudioside C Rebaudioside C (Dulcoside B) 属于甜菊糖苷(Steviol Glycosides)家族。它是甜叶菊Stevia rebaudiana Bertoni中的天然组分,是糖尿病患者和控制碳水化合物的治疗饮食中的天然甜味剂。
S4743 Wogonin Wogonin (Vogonin),在植物中发现的天然活性黄酮类化合物,是CDK9的抑制剂。在抑制CDK9的浓度下,对CDK2、CDK4和CDK6没有抑制作用。也可抑制N-acetyltransferase
S4741 Danshensu Danshensu (Salvianic acid A),是一种传统中药中的中草药,具有潜在的抗肿瘤和抗血管生成的效果。Danshensu 可抑制 CYP2E1CYP2C9,对应的IC50值分别为36.63 μm和 75.76 μm。
S4739 Oxyresveratrol Oxyresveratrol (Tetrahydroxystilbene, 2,3',4,5'-tetrahydroxystilbene)是从Morus alba L.发现的天然化合物,对酪氨酸酶的多巴氧化酶活性具有有效抑制作用,能催化黑色素生物合成的限速步骤。
S4746 (20S)-Protopanaxadiol 20(S)-Protopanaxadiol (PPD, 20-Epiprotopanaxadiol),人参皂苷在肠道的主要代谢物,是人参中的活性成分之一。20(S)-Protopanaxadiol 可在耐多种药物的癌细胞中抑制 P-glycoprotein
S4735 Salvianolic acid B Salvianolic acid B (Sal B, Lithospermate B, Lithospermic acid B)是一种抗氧化剂和自由基清除化合物,是从丹参中提取出来的最丰富的生物活性化合物。
S8318 Alantolactone Alantolactone,一种天然的桉烷类倍半萜内酯,能诱导activin/SMAD3信号、干扰Cripto-1/activin受体ⅡA型受体的相互作用。
S4707 Oleic Acid 油酸 Oleic acid (Oleate, 9-Octadecenoic Acid, Elaidoic acid)是一种天然存在于多种动物和植物脂肪和油类中的脂肪酸。它常被用作制作油酸和乳液,并作为一种药物溶剂。
S4722 (+)-Catechin (+)-Catechin (Cianidanol, Catechinic acid, Catechuic acid) 是抗氧化类黄酮,主要以(+)-catechin和(-)-epicatechin的形式存在于木本植物中。
S4723 (-)Epicatechin (−)Epicatechin (L-Epicatechin, (-)-Epicatechol)是一种类黄酮,在可可、绿茶、红酒中常见。具有强的抗氧化、胰岛素类似作用,能改善心脏健康。
S4726 Lauric Acid Lauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid)是饱和中链脂肪酸,在多种植物、动物油脂中都天然存在,是椰子油和棕榈仁油的主要成分。
S4719 Kynurenic acid Kynurenic acid (Quinurenic acid, Kynurenate)是色氨酸通过犬尿氨酸途径代谢的天然代谢物,是一种广谱的兴奋性氨基酸拮抗剂。它是NMDAR, kainate receptor和AMPA receptor的拮抗剂。
S4711 Esculetin Esculetin (Cichorigenin, Aesculetin)是在很多种天然植物产物中发现的香豆素衍生物,具有抗水肿、抗炎、抗肿瘤的生物和药理学特性,能抑制脂肪氧合酶。
S4728 3,3'-Diindolylmethane 3,3'-Diindolylmethane(DIM) 是indole-3-carbinol的主要消化产物,而indole-3-carbinol是十字花科蔬菜中一种潜在的抗癌物质。3,3'-Diindolylmethane(DIM) 是一种纯粹的 androgen receptor (AR) 的强拮抗剂。
S4708 Palmitoylethanolamide Palmitoylethanolamide (PEA, Palmidrol, N-palmitoylethanolamine) 是一种内源性的脂肪酸酰胺,能在体外选择性激活PPAR-α,EC50为3.1±0.4 μM。
S4690 Escin Escin (Aescin) 是在欧洲七叶树中所发现的皂苷混合物,具有抗炎、血管收缩的、血管保护作用。
S4686 Vitamin E Vitamin E (D-alpha-Tocopherol) 是一种脂溶性的维生素,具有有效的抗氧化特性。它是有效的过氧化氢自由基清除剂并在很多组织中,非竞争性地抑制环氧酶活性。同时通过抑制VEGF基因转录,抑制血管生成和肿瘤休眠。
S4706 Eugenol Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol)是一种自然存在的香味化合物,发现于丁香油和其他植物中。Eugenol通过增加组胺释放和细胞免疫发挥其生理作用。
S4539 Salicylic acid Salicylic acid (2-Hydroxybenzoic acid)是一种水杨酸,植物中的天然化合物,是乙烯生物合成环氧酶活性的抑制剂。
S4507 17-Hydroxyprogesterone 17-Hydroxyprogesterone (17-OHP)是一种内源性孕激素,是其他类固醇激素生物合成过程中的化学中间体。
S7867 Oleuropein Oleuropein 是一种从橄榄叶中分离出的抗氧化多酚。Oleuropein 具有抗氧化、抗炎和抗动脉粥样硬化的作用,并在体外抑制脂肪细胞的分化。Oleuropein 抑制 PPARγ 活性。Oleuropein 通过直接抑制PPARγ转录活性发挥抗脂肪形成作用。Oleuropein 还可抑制aromatase。Oleuropein 可诱导凋亡。Phase 2。
S7594 Abscisic Acid (Dormin) Abscisic Acid (Dormin, Abscisin II)是一种植物激素,参与许多植物发育过程,调节离子平衡和新陈代谢,并且抑制植物发芽和幼苗生长。
S7582 Anacardic Acid Anacardic Acid (6-pentadecylsalicylic Acid)是一个有效的p300及p300/CBP相关因子 histone acetyltranferases的抑制剂,也具有抗细菌和抗微生物活性,抑制前列腺素合成,并抑制酪氨酸酶和脂肪氧合酶。
S8036 Butein Butein,一种从漆树中分离的植物多酚,可以抑制酪氨酸激酶NF-κBSTAT3EGFR活化。
S7025 Embelin Embelin (Embelic Acid, NSC 91874),从矮地茶中分离的一种醌类化合物,是一种细胞凋亡的X染色体抑止剂(XIAP)的抑制剂,无细胞试验中IC50为4.1 μM。
S4033 Sennoside A Sennoside A (NSC 112929),一种从大黄根茎中分离得到的刺激性泻药,在肠道中引起通便作用。
S4018 Sennoside B Sennoside B,一种从大黄根茎中分离得到的刺激性泻药,抑制PDGF刺激的细胞增殖。
S2252 (+)-Usniacin (+)-Usniacin (D-Usnic Acid)是在一些地衣中发现的天然存在的二苯并呋喃类衍生物。
S2253 3-Indolebutyric acid (IBA) 3-Indolebutyric acid(IBA)是一种植物激素,用于使许多商业植物生根园艺产品。
S2424 Hypoxanthine Hypoxanthine是天然存在的嘌呤类衍生物,是尿酸合成的中间产物,由腺嘌呤核苷酸代谢而来,为黄嘌呤前体。
S2374 5-hydroxytryptophan (5-HTP) 5-Hydroxytryptophan (5-HTP, NSC-92523),在Vitamin B6存在时,通过酶芳香族-L-氨基酸脱羧酶脱羧成羟色胺(5-hydroxytryptamine 或5-HT)。
S2256 4-Methylumbelliferone (4-MU) 4-Methylumbelliferone (4-MU)是透明质酸(HA)合成抑制剂,IC50为0.4 mM。
S2375 Aloin (Barbaloin) Aloin (Barbaloin)是有效的酪氨酸酶抑制剂,作用于HeLaS3细胞,IC50为97 μM。
S2258 Esculin Esculin (Aesculin) 是一种在Horse chestnuts中发现的葡萄糖苷。
S2377 Biochanin A Biochanin A (4-Methylgenistein) 是O-甲基异黄酮,是黄酮类的一种天然有机化合物。
S2259 Aloe-emodin Aloe-emodin (NSC 38628, Rhabarberone) 是一种干扰素诱导剂,作用于JEV,IC50为1 μg/mL,作用于EV71,IC50为0.33 μg/mL。
S3071 Vanillin Vanillin (FEMA 3107),香草醛,是一种食品添加剂。
S2260 Amygdalin Amygdalin 最初从Prunus dulcis树的种子中分离的一种糖苷,也被称为苦杏仁。
S2379 Dioscin Dioscin (Collettiside III, Saponin) 是皂苷提取的,Polygonatum Zanlanscianense Pamp分离的,抑制MDA-MB-435, H14, HL60, 和 HeLa 细胞系,IC50分别为 2.6, 0.8, 7.5, 和 4.5 μM。
S2261 Andrographolide Andrographolide是一种Labdane类二萜,是药用植物Andrographis paniculata的主要生物活性成分
S2380 Diosmetin Diosmetin (Luteolin 4-methyl ether)是在Spearmint, Oregano, 和许多其他植物中发现的生物类黄酮。
S2262 Apigenin Apigenin是一种有效的CYP2C9抑制剂,Ki为2 μM.。
S2263 Arbutin Arbutin (Uva, p-Arbutin, β-Arbutin) 是一种酪氨酸酶 tyrosinase 抑制剂,对Monophenolase和Diphenolase的IC50值分别为0.9 mM 和 0.7 mM。
S2382 Evodiamine Evodiamine (Isoevodiamine)是Evodiae Fructus中提取的一种生物碱。它能通过抑制IkB kinase活性抑制NF-κB的激活。
S2384 Hematoxylin Hematoxylin (Hydroxybrazilin)易与某些金属离子,尤其是Fe(III)和Al(Ⅲ)盐,形成有色络合物。
S2266 Asiatic Acid Asiatic acid (Dammarolic acid, Asiantic acid)是积雪草苷的糖苷配基,从植物积雪草中分离而来的,常用于伤口愈合。
S2386 Indirubin (NSC 105327) Indirubin (NSC 105327) 是一种有效的细胞周期依赖性激酶和GSK-3β抑制剂,IC50约为 5 μM和0.6 μM。
S2267 Azomycin Azomycin (2-Nitroimidazole) 是Nocardia mesenterica产生的抗生素。
S2268 Baicalein Baicalein是CYP2C9和脯氨酰肽链内切酶抑制剂。
S2269 Baicalin Baicalin是脯氨酰寡肽酶的抑制剂,也是肉碱棕榈酰转移酶1(CPT1) 的变构激活剂。 Baicalin可降低 NF-κB 的表达。
S2389 Naringin Dihydrochalcone Naringin Dihydrochalcone 是一种新型甜味剂,是来自柚皮苷的一种人工甜味剂。也是一种CYP enzymes的抑制剂。
S1643 Ursodiol Ursodiol (Ursodeoxycholic acid, UDCA) 降低胆固醇吸收,并用于溶解(胆固醇)胆结石,IC50为0.22 μM。
S2270 Bergenin Bergenin (Cuscutin)是三羟基酸苷和4-O-甲基没食子酸的C-苷。
S2390 Polydatin Polydatin (Piceid) 是从多年生草本Polygonum Cuspidatum Sieb.et Zucc的根茎提取的一种结晶组分。
S2271 Berberine chloride Berberine chloride是异喹啉类生物碱的季铵盐。Berberine chloride 可激活 caspase 3caspase 8,分裂 poly ADP-ribose polymerase (PARP) 和释放 cytochrome c。Berberine chloride 可降低 c-IAP1Bcl-2Bcl-XL 的表达。Berberine chloride 可通过 JNKp38 MAPK 的持续磷酸化以及产生 ROS 来诱导凋亡。Berberine chloride 是一个 topoisomerase III 的双效抑制剂。Berberine chloride 也是一个潜在的自噬调节剂。
S2391 Quercetin Quercetin是蔬菜水果和白酒中的天然黄酮类化合物,是一种体外重组Sirt1蛋白的激活剂同时也是PI3K抑制剂,IC50为2.4 – 5.4 μM。Quercetin 可诱导凋亡和保护性的自噬。Phase 4。
S3600 Schisandrin B Schisandrin B是中草药五味子(Turcz.)中含量最丰富的二苯并环辛二烯木酚素。它是一种安全的ATRP-gp抑制剂。
S2273 β-Sitosterol β-Sitosterol (SKF 14463, 22,23-Dihydrostigmasterol)是一种植物甾醇,与胆固醇具有相似的化学结构。
S2392 Sesamin Sesamin (Fagarol, Fsesamin) 是从Fagara植物的树皮和芝麻油中分离的一种木脂素。
S2448 Gambogic Acid Gambogic Acid (Guttatic Acid, Guttic Acid, Beta-Guttiferrin)激活caspasesEC50为0.78 - 1.64 μM,且完全抑制Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1Mcl-1IC50分别为1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM 和 0.79 μM。
S2276 Bilobalide Bilobalide 是一种存在于Ginkgo biloba中的有生物活性的萜内酯。
S2277 Caffeic Acid Caffeic Acid是一种羟基肉桂酸,是一种天然存在的有机化合物。
S2281 Chrysin Chrysin (NSC 407436) 是一种天然存在的Flavone,是由Passiflora caerulea花化学提取而来的。
S2282 Cinchonidine Cinchonidine是一种生物碱,在有机化学中用于不对称合成。
S2422 Ipriflavone (Osteofix) Ipriflavone (Osteofix)是小分子物质,用于抑制骨吸收。
S2285 Cryptotanshinone (Tanshinone C) Cryptotanshinone (Tanshinone C)是一种STAT3抑制剂,无细胞试验中IC50为4.6 μM,强烈抑制STAT3 Tyr705磷酸化,对STAT3 Ser727作用效果弱,对STAT1和STAT5没有作用效果。Cryptotanshinone 可诱导ROS依赖的自噬和线粒体介导的凋亡。
S2423 (S)-10-Hydroxycamptothecin (S)-10-Hydroxycamptothecin (10-HCPT)是DNA拓扑异构酶I抑制剂,具有有效的抗肿瘤活性。
S2437 Rotundine Rotundine是一种选择性多巴胺D1受体拮抗剂, IC50为166 nM。
S2287 Cytisine Cytisine (Baphitoxine, Sophorine)是一种烟碱型乙酰胆碱受体激动剂。
S2289 Daidzin Daidzin (Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside),一种植物天然有机化合物,也是一种异黄酮,是有效的、选择性的人类线粒体醛脱氢酶抑制剂,选择性抑制ALDH-I(Ki=20 nM);而对ALDH-Ⅱ的效力至少低500倍(Ki=10 μM)。
S2385 Hordenine Hordenine是一种苯乙胺生物碱 具有抗菌特性。
S2394 Naringenin Naringenin (NSC 34875, S-Dihydrogenistein, NSC 11855, Salipurol)是来自于食用植物的一种天然的主要黄酮类化合物,有益人体健康,具有生物活性,是一种抗氧化剂,自由基清除剂,抗炎,碳水化合物代谢启动子及免疫系统的调制剂。
S2292 Diosmin Diosmin 是一种 aryl hydrocarbon receptor (AhR) 的激动剂。Diosmin 是一种半合成Phlebotropic药物,也是一种在各种柑橘类水果中发现的类黄酮。
S1973 Cyclocytidine HCl Cyclocytidine (NSC 145668) 是Cytarabine的前体药物,是一种嘧啶核苷类似物,抑制DNA synthesis,主要用于治疗白血病。
S2296 Enoxolone Enoxolone (Glycyrrhetin) 是一种通过甘草酸水解得到的β-香树脂醇型五环三萜衍生物。
S2395 Rheochrysidin Rheochrysidin (Physcione)是大承气汤的主要成分之一,用于治疗炎症。
S2297 Ergosterol Ergosterol是甾醇,是vitamin D2的生物前体(一种维生素原)。
S2396 Salidroside Salidroside (Rhodioloside) 是一种糖苷类化合物,作用于SACC-2细胞增殖,IC50为4.99±0.23 μg/mL。
S2298 Fisetin Fisetin 是有效的Sirtuin活化化合物(STAC),可以调节Sirtuin
S2397 Palmatine chloride Palmatine chloride 是Palmatine的盐酸盐,是一种小檗碱类生物碱。
S2299 Formononetin Formononetin (Formononetol, Biochanin B)是Astragalus根部的一种植物雌激素,是O-甲基异黄酮。
S2398 Coenzyme Q10 (CoQ10) Coenzyme Q10 (CoQ10) 组成电子传递链,并参与细胞有氧呼吸。在溶液中不稳定,请现配现用!
S2300 Ferulic Acid Ferulic Acid (Fumalic) 是一种羟基肉桂酸,是在Ferula assafoetida L或Ligusticum chuanxiong中发现的一种有机化合物。Ferulic acid 是一种新型的 fibroblast growth factor receptor (FGFR) 抑制剂,对FGFR1和FGFR2的IC50分别为3.78 μM和12.5 μM。
S2399 Dihydromyricetin Dihydromyricetin (Ampelopsin, Ampeloptin)是具有良好性能的天然抗氧化剂。
S2301 Genistin (Genistoside) Genistin (Genistoside, Genistine, Genistein 7-glucoside, Genistein glucoside)是在很多可以食用植物(如大豆和野葛)中发现的一种异黄酮。Genistin 通过调节 Estrogen Receptor α (ERα) 信号传导途径来减弱细胞生长并促进凋亡细胞死亡。
S2400 Rheic Acid Rhein (Monorhein, NSC 38629, Rheinic) 是Rhubarb的组成部分,是从Rheum coreanum Nakai新鲜根茎分离得到的,具有抗炎和抗肿瘤活性。Rhein 是一种FTO (mRNA N6-methyladenine demethylase)的抑制剂,并且还可抑制 AlkB repair enzymes
S2401 Sodium Danshensu Sodium Danshensu是丹参素的单钠盐,是从Salvia miltiorrhiza Bge中分离的天然酚酸,是咖啡酸衍生物。
S2303 Gossypol Acetate Gossypol Acetate (Gossypol Acetic acid, Pogosin, AT101) 是多酚醛,可渗透细胞,是一些脱氢酶(如乳酸脱氢酶、NAD-linked enzymes)的抑制剂。
S2402 Cyclovirobuxine D Cyclovirobuxine D (Cyclovirobuxin D, Cyclovirobuxine, Bebuxine, CVB-D) 是从Buxus microphylla中提取的活性化合物,用于治疗急性心肌缺血。
S2304 Gramine Gramine (Donaxine) 是一种从巨型芦苇中分离出的天然吲哚生物碱,是一种活性脂联素受体(AdipoR)激动剂,对AdipoR2和AdipoR1的IC50分别为3.2 µM和4.2 µM。 禾胺也是人和小鼠 β2-Adrenergic receptor (β2-AR) 激动剂。
S2403 Tetrandrine Tetrandrine是来源于千金藤根部的一种双苯基异喹啉,一种钙离子通道抑制剂。
S2306 Gynostemma Extract Gynostemma Extract (Gynostemma Pentaphyllum, Gypenoside)是一种从Gynostemma pentaphyllum提取而得的皂甙。
S2308 Hesperetin Hesperetin是一种生物类黄酮,更具体而言,是一种二氢黄酮。
S2309 Hesperidin Hesperidin (Cirantin)是在柑橘类水果中广泛存在的黄酮苷。
S2404 Isoliquiritigenin Isoliquiritigenin 是Glycyrrhiza glabra根系分泌的一种类黄酮,能抑制醛糖还原酶,IC50为320 nM。具有抗肿瘤活性。
S2405 Sophocarpine Sophocarpine 是人类ether-à-go-go相关基因(HERG)抑制剂,IC(50)为0.2 mM。
S2311 Hyodeoxycholic acid (HDCA) Hyodeoxycholic (HDCA, NSC 60672) acid 是一种次要的胆汁酸,是肠道细菌的代谢产物之一。
S2406 Chrysophanic Acid Chrysophanic Acid (Chrysophanol) 是Dianella longifolia中的一种天然蒽醌,是一种EGFR/mTOR通道抑制剂。
S2312 Icariin Icariin是一种cGMP特异性的PDE5抑制剂,IC50为0.432 μM,作用于PDE5比作用于PDE4选择性高167倍。
S2407 Curcumol Curcumol是常见的传统中药,具有抗肿瘤活性。
S2313 Indole-3-carbinol Indole-3-carbinol是通过降解硫代葡萄糖酸盐芸苔葡萄糖硫苷而来的,广泛存在于十字花科蔬菜中。它能够抑制NF-κBIκBα激酶的激活。
S2314 Kaempferol Kaempferol是一种黄酮,是ERRαERRγ的反向激动剂。抑制topoisomerase I催化的DNA再连接和fatty acid synthase的活性。
S1450 Nanchangmycin Nanchangmycin是一种聚醚抗生素,与Dianemycin结构相似,非常有效地防治广谱的有害线虫和昆虫,而对哺乳动物和植物没有作用效果。
S2316 Kinetin Kinetin (6-Furfuryladenine) 是一种细胞分裂素,是一类植物激素,促进细胞分裂。通常用于植物组织培养,诱导愈伤组织形成(与生长素联用),且诱导再生芽的发生。
S2319 Limonin Limonin又称Limonoate D-ring-lactone 和 Limonoic acid di-delta-lactone,化学上属于Furanolactone类化合物。
S2415 Astragaloside A Astragaloside A是从黄芪中分离的一种纯化的皂苷,广泛应用于治疗心血管疾病。
S2321 Magnolol Magnolol (NSC 293099) 是一种在Houpu magnolia (Magnolia officinalis) 树皮中发现的生物活性化合物。它能抑制TNFα诱导的NF-κB的激活。
S2322 (+)-Matrine (+)-Matrine是一种在植物Sophora属中发现的生物碱,具有多种药理作用,包括抗癌作用,是κ阿片受体激动剂。
S3032 Bindarit Bindarit是天然化合物,具有特定抗炎活性,因为选择性抑制炎症趋化因子亚家族,包括单核细胞趋化蛋白MCP-1/CCL2, MCP-3/CCL7, 和 MCP-2/CCL8。
S2326 Myricetin Myricetin, 一种具有抗氧化和抗肿瘤活性的天然黄酮,是新型的MEK1抑制剂,抑制JB6 P+小鼠表皮细胞的转化。它还能抑制PI3Kγ,Kd=0.17 μM。
S2327 Myricitrin Myricitrin (Myricitrine) 是一种化学化合物,可从Myrica cerifera (Bayberry属, 小乔木,原产于北美)的根皮中分离得到。
S2439 Guanosine Guanosine是一种嘌呤核苷。
S2329 Naringin Naringin (Naringoside) 是一种黄酮苷,是葡萄柚中的主要的类黄酮,具有柚子汁的苦味。具有抗氧化,降血脂,抗肿瘤活性,并且对cytochrome P450有抑制作用。
S2333 Nobiletin Nobiletin是O-甲基黄酮,是从柑橘果皮如橘子分离的一种黄酮类化合物。具有抗炎和抗肿瘤活性。
S2334 Oleanolic Acid Oleanolic Acid (Caryophyllin)是一种天然存在的三萜类,广泛分布于食用和药用植物,与桦木酸相关,具有相对无毒的,抗肿瘤,保肝,及抗病毒的特性。
S2335 Oridonin Oridonin是从Rabdosia rubescens中分离的对映贝壳杉烷二萜,是一种具有抗肿瘤、抗细菌和抗感染效果的传统中药。Oridonin 抑制AKT1AKT2的激酶活性,对应的IC50值分别为8.4 μM 和 8.9 μM。
S2336 Orotic acid (6-Carboxyuracil) Orotic acid (6-Carboxyuracil) 是杂环化合物,是一种酸。
S2337 Osthole Osthole 是一种香豆素类化合物。
S2338 Oxymatrine Oxymatrine (Matrine N-oxide)是一种从Sophora flavescens的根部分离的喹唑啉生物碱,具有抗炎症、抗纤维化、抗肿瘤活性,抑制iNOS表达和TGF-β/Smad通路。被用于治疗病毒性肝炎、癌症、病毒性心肌炎、胃肠出血和皮肤疾病。
S2339 Paeonol Paeonol (Peonol) 是从中草药牡丹皮和Cynanchum paniculatum中提取的主要成分。
S3603 Betulinic acid Betulinic acid (ALS-357, Lupatic acid, Betulic acid)是一种天然的五环三萜类化合物,具有抗病毒,抗疟药,抗发炎和抗肿瘤的特性。有文献报道,Betulinic acid也是 NF-κB 的活化剂。
S2341 (-)-Parthenolide (-)-Parthenolide, Nuclear Factor-κB抑制剂,可特异性地耗尽HDAC1蛋白,而不影响其他I/II类 HDACs。促进MDM2的泛素化并激活p53的细胞功能。
S2343 Phlorizin Phlorizin (Phloridzin) 是有毒的2'-葡萄糖苷根皮素,属于二氢查尔酮,是一种黄酮类化合物。Phlorizin 是一种非选择性的 SGLT 的抑制剂,对hSGLT1 和 hSGLT2的Ki值分别为300 nM 和 39 nM。Phlorizin 也是 Na+/K+-ATPase 的抑制剂。
S3604 Triptolide Triptolide是一种三环氧二萜类化合物,是从中草药雷公藤中提取的免疫抑制剂。它是一种NF-κB抑制剂,抑制NF-κB转录活性,破坏p65/CBP的相互作用,减少p65蛋白。Triptolide (PG490) 可抑制 heat shock transcription factor 1 (HSF1) 的反式激活。Triptolide 可抑制 MDM2 并通过一个p53非依赖性通路来诱导凋亡。
S2344 Piperine Piperine (1-Piperoylpiperidine) 是一种生物碱,是造成黑胡椒和长胡椒辛辣的原因,也用于一些传统医学领域,且作为杀虫剂。
S2346 Puerarin Puerarin (Kakonein) 是一种5-HT2C受体和苯二氮位点拮抗剂。
S2347 Quercetin Dihydrate Quercetin (Sophoretin) 是一种多酚类黄酮,存在于多种植物性食品中,例如苹果,洋葱,浆果和红酒,由于其神经系统和抗癌作用而被用于许多不同的文化中。Quercetin (Sophoretin) 作为天然类黄酮,是重组SIRT1PI3K抑制剂的刺激物,对PI3Kγ,PI3Kδ和PI3Kβ的IC50分别为2.4μM,3.0μM和5.4μM。
S2349 Rutaecarpine Rutaecarpine (Rutecarpine) 是从 Evodia rutaecarpa和相关草药中分离的indolopyridoquinazolinone生物碱。是一种新型的COX2抑制剂。
S2350 Rutin Rutin (Rutoside)是在许多植物中发现的一种黄酮苷,包括Buckwheat; Tobacco; Forsythia; Hydrangea; Viola, 等。
S2351 Salicin Salicin (Salicoside, Salicine)是一种醇-β-糖苷,含有D-葡萄糖。是柳树皮产生的一种抗炎剂。它是一种天然的、非选择性的COX1COX2抑制剂。
S2354 Sclareol Sclareol 是一种芳香化合物,在Clary sage(Salvia sclarea)中发现而因此命名,被归类为双环二萜醇。
S2355 Sclareolide Sclareolide (Norambreinolide) 是一种倍半萜内酯天然产物,来源于各种植物,包括Salvia sclarea, Salvia yosgadensis, 和 cigar tobacco。
S2356 Shikimic Acid Shikimic acid (Shikimate) 通常所知的是其阴离子形式Shikimate,在植物和微生物中,是一种重要的生化中间体。
S2357 Silibinin (NSC 651520) Silibinin (NSC 651520, Silybin, Silibinin A, Silymarin I, Flavobin)是Silymarin的主要活性成分。
S2358 Silymarin Silymarin (Silybin B)是一种强效的新型自由基清除剂,用于治疗急性脑梗死患者。
S2359 Sinomenine Sinomenine (Cucoline, Kukoline) 是一种传统中草药,用于治疗风湿病和关节炎。
S2361 Stigmasterol Stigmasterol 是一种不饱和植物甾醇,具有抗癌,解热,抗炎和免疫调节作用。
S2362 Synephrine Synephrine (Oxedrine)是从苦橘及其他柑橘属植物中提取的一种不饱和的植物甾醇,常用于减肥。
S2363 Tangeretin Tangeretin (Tangeritin)是一种天然的多甲氧基黄酮,集中在柑橘的果皮中,已知具有抗增殖、抗侵袭、抗转移和抗氧化活性。
S2364 Tanshinone I Tanshinone I 由丹参分离而来的。
S2365 Tanshinone IIA Tanshinone IIA (Tanshinone B) 是丹参和Salviae miltiorrhizae Radix中最丰富的二萜醌类,用于治疗心血管疾病和炎症性疾病。是天然的monoacylglycerol lipase抑制剂。
S2366 Taxifolin (Dihydroquercetin) Taxifolin(Dihydroquercetin)是一种二氢黄酮醇类,是一种黄酮类化合物。是I型VEGFR2 kinase的抑制剂。
S2368 Theobromine Theobromine (3,7-Dimethylxanthine)是黄嘌呤生物碱,作为一种支气管扩张剂,血管扩张剂。
S2371 Vanillylacetone Vanillylacetone (NSC 15335) 在化学结构上与其他香料,如Vanillin 和 Eugenol类似,用来作为一种香味味添加剂。Vanillylacetone (Zingerone) 可减轻氧化应激和炎症,下调NF-κB介导的信号通路。Zingerone 充当抗有丝分裂剂,并抑制神经母细胞瘤细胞的生长。
S2372 Xanthone Xanthone (Genicide)是一种有机化合物,可以由加热水杨酸苯酯制备而得到。
S2373 Yohimbine HCl Yohimbine (Antagonil) 是一种瞳孔放大剂,用于治疗阳痿,也是一种春药。
E2709 Halofuginone hydrobromide Halofuginone (RU-19110) hydrobromid, a febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity.
E2741 7-ketocholesterol 7-Ketocholesterol (7-Oxocholesterol) 是一种生物活性甾醇和重要的胆固醇氧化产物,是 HMG-CoA 还原酶细胞色素 P450 7A1 的强抑制剂。 它增强巨噬细胞的氧化应激、内质网应激和细胞凋亡。
E2456 Soyasaponin Bb Soyasaponin Bb是一种从Phaseolus vulgaris中分离出来的大豆皂苷,是一种醛糖还原酶 (aldose reductase, AKR1B1)差异抑制剂 (ARDI)。
S4745 L-Phenylalanine L-Phenylalanine是一种必需氨基酸,是NMDAR甘氨酸和谷氨酸结合位点的竞争性拮抗剂,Kb为573μM。它广泛用于食品调味剂和药品生产。
E0755 Guvacoline hydrochloride Norarecoline hydrochloride (Guvacoline hydrochloride)是一种在槟榔(Areca triandra)中发现的吡啶类生物碱,可作为心房和回肠毒蕈碱受体的完全激动剂。
E0760 Neotuberostemonine Neotuberostemonine (NTS) 是对叶百部(Stemona tuberosa)中的主要镇咳生物碱之一,能够通过抑制巨噬细胞的募集和M2极化对BLM诱导的肺纤维化起到显著的保护作用。
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