- Bcl-2
- Bcl-B
- Bcl-w
- Bcl-xL
- Mcl-1
- Bax
- Bfl-1
- Bad
- Bcl-xL
Bfl-1 抑制剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S8061 | Sabutoclax | Sabutoclax (BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively. | Pan | Bfl-1, IC50: 0.62 μM |
| S2448 | Gambogic Acid | Gambogic Acid (Guttatic Acid, Guttic Acid, Beta-Guttiferrin) activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively. | Pan | Bfl-1, IC50: 1.06 μM |
