- Carbonic Anhydrase I
- Carbonic Anhydrase II
- Carbonic Anhydrase IV
- Carbonic Anhydrase IX
- Carbonic Anhydrase XII
Carbonic Anhydrase II 选择性抑制剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S1375 | Dorzolamide HCl | Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. | Selective | Carbonic anhydrase II, Ki: 1.9 nM |
| S3178 | Brinzolamide | Brinzolamide (AL-4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. | Selective | CAII, IC50: 3.19 nM |
| S4039 | Methazolamide | Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. | Pan | hCAII, Ki: 14 nM |
