| S5422 |
Trimethyloctadecylammonium bromide |
Trimethyloctadecylammonium bromide (Octadecyltrimethylammonium bromide, OcTMAB, C18TAB) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ. |
Selective |
Dynamin I, IC50: 1.9 μM |
| S7162 |
Mdivi-1 |
Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis. |
Selective |
Dnm1 GTPase, IC50: 1 μM-10 μM |
| S7163 |
Dyngo-4a |
Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1 μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively.
|
Pan |
DynI (brain), IC50: 0.38 μM; DynI (rec), IC50: 1.1 μM |
