- HDAC1
- HDAC2
- HDAC3
- HDAC4
- HDAC5
- HDAC6
- HDAC7
- HDAC8
- HDAC9
- HDAC10
- HDAC11
- HD1
- HD2
HD1 选择性抑制剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S1484 | MC1568 | MC1568 is a selective HDAC inhibitor for maize HD1-A with IC50 of 100 nM in a cell-free assay. It is 34-fold more selective for HD1-A than HD1-B. | Selective | HD1-A (Maize), IC50: 100 nM; HD1-B (Maize), IC50: 3.4 μM |
| S2170 | Givinostat (ITF2357) | Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM in cell-free assays. Phase 2. | Pan | HD1-B, IC50: 7.5 nM; HD1-A, IC50: 16 nM |
