- PARP1
- PARP2
- PARP3
- Tankyrase-1
- Tankyrase-2
- PARP14
- PARP7
- TNKS1
- TNKS2
PARP14 选择性抑制剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S8992 | RBN012759 | RBN012759 is a potent and selective inhibitor of PARP14 with IC50 of <3 nM and 5 nM for human catalytic domain and mouse catalytic domain, respectively. RBN012759 contributes to anti-tumor immune response. | Selective | human PARP14, IC50: <3 nM; mouse PARP14, IC50: 5 nM |
| S0732 | GeA-69 | GeA-69 is a cell-permeable, selective allosteric inhibitor targeting macrodomain 2 (MD2) of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) with Kd of 860 nM. | Selective | PARP14-MD2, Kd: 860 nM |
