PDK1 选择性抑制剂
| 目录号 |
产品名 |
产品描述 |
Selective / Pan |
IC50 / Ki |
| S2949 |
KPLH1130 |
KPLH1130 is a specific inhibitor of pyruvate dehydrogenase kinase (PDK) that blocks macrophage polarization and attenuates proinflammatory responses. |
Selective |
PDK, Ki: 10 μM |
| S0983 |
JX06 |
JX06 is a selective covalent inhibitor of PDK1 in cells. JX06 dose-dependently inhibits PDK1, PDK2 and PDK3 with IC50 0.049 μM, 0.101 μM and 0.313 μM, respectively. |
Pan |
PDK1, IC50: 0.049 μM |
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