TNKS1 抑制剂
| 目录号 |
产品名 |
产品描述 |
Selective / Pan |
IC50 / Ki |
| S6739 |
MN 64 |
MN-64 is a potent inhibitor of TNKS1 and TNKS2 with IC50 value of 6 and 72 nM, respectively. |
Pan |
TNKS1, IC50: 6 nM |
| S1180 |
XAV-939 |
XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β. |
Pan |
TNKS1, IC50: 11 nM |
| S7239 |
G007-LK |
G007-LK is a potent and selective tankyrase inhibitor with IC50 of 46 nM and 25 nM for TNKS1/2, respectively.
|
Pan |
TNKS1, IC50: 46 nM |
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