TrxR 选择性抑制剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S4307	Auranofin	Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.	Selective	TrxR, IC50: 88 nM