Decarboxylase
Decarboxylase产品
- 所有产品(15)
- Decarboxylase抑制剂 (12)
- Decarboxylase抗体 (1)
- Decarboxylase激活剂 (1)
| 目录号 | 产品名 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|---|
| S4582 | Eflornithine (DFMO) hydrochloride hydrate | Eflornithine (DFMO) hydrochloride hydrate通过对鸟氨酸脱羧酶的不可逆抑制作用，抑制多胺生物合成。它是一种化疗保护剂，可阻止血管生成。其生物半衰期为8小时。 | ||
| S2453 | Benserazide HCl | Benserazide HCl (Ro-4-4602)是一种外周性的芳香族L-氨基酸脱羧酶（AAAD）或DOPA脱羧酶抑制剂。在溶液中不稳定，请现配现用！ | ||
| S1891 | Carbidopa | Carbidopa 是一种芳香族-L-氨基酸脱羧酶抑制剂，IC50为29±2 μM。 | ||
| S0108 | AZ-33 | AZ-33 (LDHA Inhibitor 33)是一种 lactate dehydrogenase A (LDHA) 的有效抑制剂，其IC50值为0.5 μM。LDHA是参与厌氧糖酵解的关键酶，在人类恶性肿瘤中该酶经常失活。 | ||
| S3086 | Maleic acid | Maleic acid 可抑制 glutamate decarboxylase (GAD) 的活性，从而增强 Listeria monocytogenes 的酸敏感性。Maleic acid 会影响细胞外 GABA 的水平。 | ||
| E2354 | Valepotriate | Valepotriate从Valeriana jatamansi Jones中分离一种不稳定的环烯醚萜，通过显著增加GABAA、谷氨酸脱羧酶65 (glutamic acid decarboxylase 65)和Bcl-2的表达，以及降低caspase-3表达发挥抗癫痫作用。 | ||
| F0074New | GAD67 mAb | Anti-GAD67 Mouse mAb recognizes endogenous levels of total GAD67 protein. | ||
| S1642 | Methyldopa | Methyldopa 是DOPA 脱羧酶竞争性抑制剂，ED50为21.8 mg/kg。 | ||
| A5290 | GAD67 Rabbit Recombinant mAb | |||
| E0654 | D-Arginine | D-Arginine是精氨酸脱羧酶(arginine decarboxylase,ADC)的抑制剂，可调节腐胺的生物合成。 | ||
| S5448 | S(-)-Carbidopa | S(-)-Carbidopa is a peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism. | ||
| E1189 | TES-1025 | TES-1025是一种高效、选择性的人α-氨基-β-羧酸-ε-半醛脱羧酶（human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, ACMSD）抑制剂，其IC50为13 nM。 | ||
| S5444 | 4-Bromo-3-hydroxybenzoic acid | 4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with resultant inhibition of histamine formation in mammals. | ||
| S5579 | Chelidonic acid | Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid) 是在几种植物中发现的次级代谢产物，对实验动物的过敏性疾病具有治疗潜力。Chelidonic acid 通过阻断HMC-1细胞中的 NF-κB 和 caspase-1 来抑制 IL-6 的产生。Chelidonic acid 也是 glutamate decarboxylase 的抑制剂，其Ki值为1.2 μM。 | ||
| S5409 | Chelidamic acid hydrate | Chelidamic acid is a pharmaceutical intermediate as well as a cosmetic material due to its anti-inflammatory and whitening effect. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. | ||
| S4582 | Eflornithine (DFMO) hydrochloride hydrate | Eflornithine (DFMO) hydrochloride hydrate通过对鸟氨酸脱羧酶的不可逆抑制作用，抑制多胺生物合成。它是一种化疗保护剂，可阻止血管生成。其生物半衰期为8小时。 | ||
| S2453 | Benserazide HCl | Benserazide HCl (Ro-4-4602)是一种外周性的芳香族L-氨基酸脱羧酶（AAAD）或DOPA脱羧酶抑制剂。在溶液中不稳定，请现配现用！ | ||
| S1891 | Carbidopa | Carbidopa 是一种芳香族-L-氨基酸脱羧酶抑制剂，IC50为29±2 μM。 | ||
| S0108 | AZ-33 | AZ-33 (LDHA Inhibitor 33)是一种 lactate dehydrogenase A (LDHA) 的有效抑制剂，其IC50值为0.5 μM。LDHA是参与厌氧糖酵解的关键酶，在人类恶性肿瘤中该酶经常失活。 | ||
| S3086 | Maleic acid | Maleic acid 可抑制 glutamate decarboxylase (GAD) 的活性，从而增强 Listeria monocytogenes 的酸敏感性。Maleic acid 会影响细胞外 GABA 的水平。 | ||
| S1642 | Methyldopa | Methyldopa 是DOPA 脱羧酶竞争性抑制剂，ED50为21.8 mg/kg。 | ||
| E0654 | D-Arginine | D-Arginine是精氨酸脱羧酶(arginine decarboxylase,ADC)的抑制剂，可调节腐胺的生物合成。 | ||
| S5448 | S(-)-Carbidopa | S(-)-Carbidopa is a peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism. | ||
| E1189 | TES-1025 | TES-1025是一种高效、选择性的人α-氨基-β-羧酸-ε-半醛脱羧酶（human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, ACMSD）抑制剂，其IC50为13 nM。 | ||
| S5444 | 4-Bromo-3-hydroxybenzoic acid | 4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with resultant inhibition of histamine formation in mammals. | ||
| S5579 | Chelidonic acid | Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid) 是在几种植物中发现的次级代谢产物，对实验动物的过敏性疾病具有治疗潜力。Chelidonic acid 通过阻断HMC-1细胞中的 NF-κB 和 caspase-1 来抑制 IL-6 的产生。Chelidonic acid 也是 glutamate decarboxylase 的抑制剂，其Ki值为1.2 μM。 | ||
| S5409 | Chelidamic acid hydrate | Chelidamic acid is a pharmaceutical intermediate as well as a cosmetic material due to its anti-inflammatory and whitening effect. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. | ||
| A5290 | GAD67 Rabbit Recombinant mAb | |||
| E2354 | Valepotriate | Valepotriate从Valeriana jatamansi Jones中分离一种不稳定的环烯醚萜，通过显著增加GABAA、谷氨酸脱羧酶65 (glutamic acid decarboxylase 65)和Bcl-2的表达，以及降低caspase-3表达发挥抗癫痫作用。 | ||
| F0074New | GAD67 mAb | Anti-GAD67 Mouse mAb recognizes endogenous levels of total GAD67 protein. |
Decarboxylase抑制剂选择性比较
Tags: Decarboxylase inhibition | Decarboxylase pathway | Decarboxylase activation | Decarboxylase inhibitor review
