| S1466 |
Calcitriol (1,25-Dihydroxyvitamin D3)
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Calcitriol作为vitamin D的激素活性形式，是一种非选择性vitamin D receptor的激活剂，对vitamin D receptor的结合亲和力(IC50=0.4 nM)是选择性VDRA paricalcitol的10倍以上。在溶液中不稳定，请现配现用！ |
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Cell Commun Signal, 2025, 23(1):104
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Cancer Sci, 2025, 116(7):1871-1882
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Cureus, 2025, 17(4):e82934
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| S2298 |
Fisetin
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Fisetin 是有效的Sirtuin活化化合物(STAC)，可以调节Sirtuin。 |
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Sci Adv, 2025, 11(17):eads1875
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Mol Cancer, 2024, 23(1):222
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Cell Death Dis, 2024, 15(8):608
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| S5259 |
β-nicotinamide mononucleotide (NMN)
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Nicotinamide mononucleotide (β-NM, NMN)是NAD+的关键前体之一，也是NAMPT反应的产物，通过烟酰胺单核苷酸腺苷酸转移酶转化为NAD+。 |
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Nat Commun, 2025, 16(1):212
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MedComm (2020), 2025, 6(3):e70075
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PLoS Pathog, 2025, 21(5):e1013163
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| S1236 |
Leucovorin Calcium Pentahydrate (Folinic acid)
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Leucovorin (Folinic acid) Calcium Pentahydrate是一种亚叶酸, 用于改善叶酸下降的状况。在溶液中不稳定，请现配现用！ |
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J Exp Clin Cancer Res, 2025, 44(1):13
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iScience, 2024, 27(10):110862
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Cell Rep Med, 2023, 4(10):101200
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| S5726 |
Liothyronine (Triiodothyronine, T3)
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T3 (Triiodothyronine)是一种甲状腺激素，会影响人体的各种生理过程，包括生长发育、新陈代谢、体温和心率等。 |
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STAR Protocols, 2025, 103834
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STAR Protoc, 2025, 6(2):103834
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Cancers (Basel), 2024, 16(23)4069
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| S5992 |
Heparan Sulfate
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Heparan sulfate (HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan) 是HS proteoglycans (HSPGs)的成分，是一种存在于细胞表面的线性多糖。Heparan sulfate 可影响小肠上皮细胞(IECs)与 Wnt 的结合亲和力，从而促进经典Wnt信号的激活并促进小肠隐窝上皮损伤后的再生。 |
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Mol Ther Methods Clin Dev, 2025, 33(1):101426
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iScience, 2024, 27(6):110120
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bioRxiv, 2024, 2024.05.23.595417
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| S2935 |
Nicotinamide Riboside Chloride (NR-Cl)
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Nicotinamide Riboside Chloride是烟酰胺核糖(NR)的氯化物盐形式。NR是维生素B3的衍生物，可作为作为NAD或NAD+的前体。 |
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bioRxiv, 2025, 2025.07.10.663928
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bioRxiv, 2025, 2025.01.06.631511
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Front Physiol, 2023, 14:1164287
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| S5109 |
Ademetionine (S-Adenosylmethionine)
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Ademetionine (AdoMet, S-Adenosylmethionine, SAMe), also known as SAMe, is a specific form of the amino acid methionine known as S-adenosyl-methionine. It is essential for the formation of glutathione, a water-soluble peptide that helps the body fight free radicals. |
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Pharmaceuticals (Basel), 2025, 18(9)1395
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J Oral Microbiol, 2024, 16(1):2292375
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Nat Metab, 2023, 10.1038/s42255-023-00861-4
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| S9793 |
4-HNE (4-Hydroxynonenal)
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4-HNE (4-Hydroxynonenal)是脂质过氧化的主要终产物之一，已被广泛接受为氧化应激的诱导剂。 |
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Circulation, 2024, 1752-1769
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Nature Communications, 2022, 5545
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Nat Commun, 2022, 13(1):5545
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| S5324 |
6-OHDA (Oxidopamine hydrobromide)
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6-OHDA (Oxidopamine hydrobromide)是一种合成有机化合物，可作为具有潜在抗肿瘤活性的神经递质多巴胺（dopamine）的拮抗剂。6-OHDA (Oxidopamine hydrobromide) 可用于诱导帕金森病动物模型。在溶液中不稳定，请现配现用！ |
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Cancer Discovery, 2025, 202-226
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PLoS One, 2024, 19(12):e0316179
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Ther Adv Chronic Dis, 2021, 12:2040622321998139
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| S6010 |
Sodium L-lactate
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Sodium L-lactate被用作是一种食品添加剂、防腐剂、酸度调节剂和膨胀剂。 |
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Cell Commun Signal, 2025, 23(1):104
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J Transl Med, 2025, 23(1):69
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EMBO Rep, 2024, 25(12):5599-5619
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| S1031 |
3-Hydroxybutyric acid (BHB acid)
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3-Hydroxybutyric acid (BHB)是一种在I型糖尿病中升高的小分子代谢产物。 |
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BMC Med, 2022, 20(1):148
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BMC Medicine, 2022, 148
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| S5260 |
ATP (Adenosine 5'-triphosphate)
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ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) 是一种多功能的三磷酸核苷，是免疫和炎症反应中重要的内源性信号分子。 |
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Adv Sci (Weinh), 2025, 12(40):e09838
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Stem Cell Res Ther, 2025, 16(1):206
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Cell Rep, 2024, 43(2):113779
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