| S1466 |
Calcitriol
|
Calcitriol作为vitamin D的激素活性形式，是一种非选择性vitamin D receptor的激活剂，对vitamin D receptor的结合亲和力(IC50=0.4 nM)是选择性VDRA paricalcitol的10倍以上。在溶液中不稳定，请现配现用！ |
-
Cell Commun Signal, 2025, 23(1):104
-
Cancer Sci, 2025, 116(7):1871-1882
-
Cureus, 2025, 17(4):e82934
|
|
| S5259 |
β-nicotinamide mononucleotide (NMN)
|
Nicotinamide mononucleotide (β-NM, NMN)是NAD+的关键前体之一，也是NAMPT反应的产物，通过烟酰胺单核苷酸腺苷酸转移酶转化为NAD+。 |
-
Nat Commun, 2025, 16(1):212
-
MedComm (2020), 2025, 6(3):e70075
-
PLoS Pathog, 2025, 21(5):e1013163
|
|
| S1709 |
Estradiol
|
Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol)是一种人类性激素和类固醇，也是主要的女性性激素。Estradiol 可通过 estrogen receptor β (ERβ) 通路来上调 IL-6 的表达。 |
-
Cancer Cell, 2025, 43(5):891-904.e10
-
Nat Commun, 2025, 16(1):758
-
Cell Rep Med, 2025, 6(7):102192
|
|
| S5992 |
Heparan Sulfate
|
Heparan sulfate (HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan) 是HS proteoglycans (HSPGs)的成分，是一种存在于细胞表面的线性多糖。Heparan sulfate 可影响小肠上皮细胞(IECs)与 Wnt 的结合亲和力，从而促进经典Wnt信号的激活并促进小肠隐窝上皮损伤后的再生。 |
-
Mol Ther Methods Clin Dev, 2025, 33(1):101426
-
iScience, 2024, 27(6):110120
-
bioRxiv, 2024, 2024.05.23.595417
|
|
| S2518 |
NAD+ (β-DPN)
|
NAD+ (β-DPN, β-NAD, β-Nicotinamide Adenine Dinucleotide,nicotinamide adenine dinucleotide)是一种辅酶，由Ribosylnicotinamide 5'-二磷酸与腺苷5'-磷酸通过焦磷酸键合而偶联而成的。 |
-
Nat Commun, 2022, 13(1):7335
-
New Phytol, 2022, 233(2):890-904
-
Cell Rep, 2021, 37(8):110038
|
|
| S5109 |
S-Adenosyl-L-methionine (Ademetionine)
|
Ademetionine (AdoMet, S-Adenosylmethionine, SAMe), also known as SAMe, is a specific form of the amino acid methionine known as S-adenosyl-methionine. It is essential for the formation of glutathione, a water-soluble peptide that helps the body fight free radicals. |
-
Pharmaceuticals (Basel), 2025, 18(9)1395
-
J Oral Microbiol, 2024, 16(1):2292375
-
Nat Metab, 2023, 10.1038/s42255-023-00861-4
|
|
| S9793 |
4-HNE (4-Hydroxynonenal)
|
4-HNE (4-Hydroxynonenal)是脂质过氧化的主要终产物之一，已被广泛接受为氧化应激的诱导剂。 |
-
Nat Commun, 2022, 13(1):5545
|
|
