MicroRNA

MicroRNA产品

  • 所有产品(8)
  • MicroRNA抑制剂 (3)
  • MicroRNA激活剂 (1)
  • MicroRNA调节剂 (2)
目录号 产品名 产品描述 文献引用 实验数据
S1288 Camptothecin (CPT) Camptothecin (CPT)是一种特异性的DNA拓扑异构酶I (Topo I)抑制剂,IC50为0.68 μM。Camptothecin 在癌细胞中可通过microRNA-125b介导的线粒体信号通路来诱导凋亡。Phase 2。
Nat Commun, 2024, 15(1):4430
Exp Mol Med, 2024, 56(3):656-673
EMBO Rep, 2024,
F0519New Argonaute-2 Rabbit mAb AGO2,Ago2/eIF2C2,Argonaute 2,Argonaute-2,EIF2C2,RIPAb+ Ago2 - RIP Validated
F0622New Argonaute 1 Rabbit mAb
S3084 Guanosine 5'-triphosphate trisodium salt Guanosine 5'-triphosphate (5'-GTP, Guanosine triphosphate, H4GTP) trisodium salt 是鼠细胞中成肌细胞分化的增强剂。Guanosine 5'-triphosphate trisodium salt 可上调miRNA(特别是miR133a和miR133b)和肌原性调节因子,并诱导人肌原性前体细胞在细胞外环境中释放出被鸟苷基分子(主要是鸟苷)填充的外泌体。
E3687 Radix Actinidiae Extract Radix Actinidiae Extract来源于藤梨根Radix Actinidiae,即猕猴桃Actinidia chinensis Planch.的根,可通过调控微小核糖核酸(miRNA)的表达发挥抗癌作用。
S3309 Solasodine Solasodine (Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine) 是一种存在于茄科植物中的有毒的生物碱化合物。Solaso​​dine 可降低 matrix metalloproteinase-2 (MMP-2)MMP-9matrix metalloproteinase (EMMPRIN) 的细胞外诱导剂的mRNA水平,但会增加 reversion-inducing cysteine-rich protein with kazal motifs (RECK)。Solaso​​dine 下调致癌的 microRNA-21 (miR-21),已知其靶向RECK。Solaso​​dine 还可以减少 PI3K/Akt 信号传导途径并下调miR-21的表达。
S9067 Pseudoprotodioscin Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9665 Motixafortide (BL-8040) Motixafortide (BL-8040, BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140) 是一种 CXCR4 的拮抗剂,IC50值约为1 nM。BL-8040 通过改变的miR-15a/16-1的表达,下调 ERKBCL-2MCL-1cyclin-D1,诱导AML胚的凋亡。
S1288 Camptothecin (CPT) Camptothecin (CPT)是一种特异性的DNA拓扑异构酶I (Topo I)抑制剂,IC50为0.68 μM。Camptothecin 在癌细胞中可通过microRNA-125b介导的线粒体信号通路来诱导凋亡。Phase 2。
Nat Commun, 2024, 15(1):4430
Exp Mol Med, 2024, 56(3):656-673
EMBO Rep, 2024,
S3309 Solasodine Solasodine (Purapuridine, Solancarpidine, Solasodin, Salasodine, Salasdine) 是一种存在于茄科植物中的有毒的生物碱化合物。Solaso​​dine 可降低 matrix metalloproteinase-2 (MMP-2)MMP-9matrix metalloproteinase (EMMPRIN) 的细胞外诱导剂的mRNA水平,但会增加 reversion-inducing cysteine-rich protein with kazal motifs (RECK)。Solaso​​dine 下调致癌的 microRNA-21 (miR-21),已知其靶向RECK。Solaso​​dine 还可以减少 PI3K/Akt 信号传导途径并下调miR-21的表达。
S9067 Pseudoprotodioscin Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S3084 Guanosine 5'-triphosphate trisodium salt Guanosine 5'-triphosphate (5'-GTP, Guanosine triphosphate, H4GTP) trisodium salt 是鼠细胞中成肌细胞分化的增强剂。Guanosine 5'-triphosphate trisodium salt 可上调miRNA(特别是miR133a和miR133b)和肌原性调节因子,并诱导人肌原性前体细胞在细胞外环境中释放出被鸟苷基分子(主要是鸟苷)填充的外泌体。
E3687 Radix Actinidiae Extract Radix Actinidiae Extract来源于藤梨根Radix Actinidiae,即猕猴桃Actinidia chinensis Planch.的根,可通过调控微小核糖核酸(miRNA)的表达发挥抗癌作用。
S9665 Motixafortide (BL-8040) Motixafortide (BL-8040, BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140) 是一种 CXCR4 的拮抗剂,IC50值约为1 nM。BL-8040 通过改变的miR-15a/16-1的表达,下调 ERKBCL-2MCL-1cyclin-D1,诱导AML胚的凋亡。
F0519New Argonaute-2 Rabbit mAb AGO2,Ago2/eIF2C2,Argonaute 2,Argonaute-2,EIF2C2,RIPAb+ Ago2 - RIP Validated
F0622New Argonaute 1 Rabbit mAb

MicroRNA抑制剂选择性比较

Tags: MicroRNA inhibitor|MicroRNA agonist|MicroRNA activator|MicroRNA inducer|MicroRNA antagonist|MicroRNA signaling pathway|MicroRNA assay kit
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