Mineralocorticoid Receptor
Mineralocorticoid Receptor产品
- 所有产品(5)
- Mineralocorticoid Receptor抑制剂 (1)
- Mineralocorticoid Receptor拮抗剂 (4)
| 目录号 | 产品名 | 产品描述 | 文献引用 | 实验数据 |
|---|---|---|---|---|
| S1707 | Eplerenone | Eplerenone是一类mineralocorticoid receptor 拮抗剂，阻断了醛固酮的作用，用于控制高血压。 | ||
| E1239 | Apararenone | Apararenone (MT-3995) 是一种选择性的长效非甾体盐皮质激素受体(mineralocorticoid receptors, MR)拮抗剂。 | ||
| S5273 | Canrenone | Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases. | ||
| S9702 | Finerenone | Finerenone (FIN, BAY 94-8862) 是一种高度选择性的、口服活性的 mineralocorticoid receptor (MR) 的非甾体拮抗剂，IC50值为18 nM。Finerenone 具有研究诸如2型糖尿病和慢性肾脏病等心肾疾病的潜力。 | ||
| E0704 | Esaxerenone (CS-3150) | Esaxerenone (CS-3150)是一种选择性非甾体盐皮质受体(nonsteroidal mineralocorticoid receptor, MR)拮抗剂，与盐皮质受体结合，抑制(3)H-醛固酮与盐皮质受体结合，IC50为9.4 nM。Esaxerenone (CS-3150)增加蛋白尿恢复到正常水平的可能性，并减少蛋白尿进展到更高水平。 | ||
| E0704 | Esaxerenone (CS-3150) | Esaxerenone (CS-3150)是一种选择性非甾体盐皮质受体(nonsteroidal mineralocorticoid receptor, MR)拮抗剂，与盐皮质受体结合，抑制(3)H-醛固酮与盐皮质受体结合，IC50为9.4 nM。Esaxerenone (CS-3150)增加蛋白尿恢复到正常水平的可能性，并减少蛋白尿进展到更高水平。 | ||
| S1707 | Eplerenone | Eplerenone是一类mineralocorticoid receptor 拮抗剂，阻断了醛固酮的作用，用于控制高血压。 | ||
| E1239 | Apararenone | Apararenone (MT-3995) 是一种选择性的长效非甾体盐皮质激素受体(mineralocorticoid receptors, MR)拮抗剂。 | ||
| S5273 | Canrenone | Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases. | ||
| S9702 | Finerenone | Finerenone (FIN, BAY 94-8862) 是一种高度选择性的、口服活性的 mineralocorticoid receptor (MR) 的非甾体拮抗剂，IC50值为18 nM。Finerenone 具有研究诸如2型糖尿病和慢性肾脏病等心肾疾病的潜力。 |
Mineralocorticoid Receptor抑制剂选择性比较
Tags: Mineralocorticoid Receptor inhibitor|Mineralocorticoid Receptor agonist|Mineralocorticoid Receptor activator|Mineralocorticoid Receptor inducer|Mineralocorticoid Receptor antagonist|Mineralocorticoid Receptor signaling pathway|Mineralocorticoid Receptor assay kit
