HL60 |
Function assay |
2 uM |
48 hrs |
Induction of differentiation in human HL60 cells assessed as increase in CD11b positive cells at 2 uM incubated for 48 hrs by 7-AAD staining-based flow cytometric analysis |
31408809 |
SH-SY5Y |
Function assay |
10 uM |
72 hrs |
Induction of neurogenesis in human SH-SY5Y cells assessed as stimulation of neurite outgrowth at 10 uM incubated for 72 hrs by phase contrast microscopic analysis |
30996781 |
SH-SY5Y |
Function assay |
10 uM |
24 hrs |
Induction of neurogenesis in human SH-SY5Y cells assessed as upregulation of MAP-2 mRNA at 10 uM incubated for 24 hrs by RT-PCR analysis |
30996781 |
SH-SY5Y |
Function assay |
10 uM |
24 hrs |
Induction of neurogenesis in human SH-SY5Y cells assessed as upregulation of N-myc mRNA at 10 uM incubated for 24 hrs by RT-PCR analysis |
30996781 |
SH-SY5Y |
Function assay |
10 uM |
24 hrs |
Induction of neurogenesis in human SH-SY5Y cells assessed as upregulation of GAP43 mRNA at 10 uM incubated for 24 hrs by RT-PCR analysis |
30996781 |
NB4 |
Function assay |
10 to 30 uM |
6 days |
Induction of granulocytic differentiation in human NB4 cells assessed as increase in CD14 positive cells at 10 to 30 uM after 6 days by FITC staining based flow cytometry analysis |
30925338 |
HL60 |
Function assay |
10 to 30 uM |
6 days |
Induction of granulocytic differentiation in human HL60 cells assessed as increase in CD14-FITC positive cells at 10 to 30 uM after 6 days by flow cytometry analysis |
30925338 |
NB4 |
Function assay |
10 to 30 uM |
6 days |
Induction of granulocytic differentiation in human NB4 cells assessed as increase in CD11c-APC positive cells at 10 to 30 uM after 6 days by flow cytometry analysis |
30925338 |
HL60 |
Function assay |
10 to 30 uM |
6 days |
Induction of granulocytic differentiation in human HL60 granulocytic assessed as increase in CD11c-APC positive cells at 10 to 30 uM after 6 days by flow cytometry analysis |
30925338 |
NB4 |
Function assay |
10 to 30 uM |
6 days |
Induction of granulocytic differentiation in human NB4 cells assessed as increase in CD11b-APC-Cy7 positive cells at 10 to 30 uM after 6 days by flow cytometry analysis |
30925338 |
NB4 |
Function assay |
30 uM |
72 hrs |
Inhibition of colony formation in human NB4 cells at 30 uM preincubated for 72 hrs followed by compound washout and measured after 7 to 10 days |
30925338 |
HL60 |
Function assay |
30 uM |
72 hrs |
Inhibition of colony formation in human HL60 cells at 30 uM preincubated for 72 hrs followed by compound washout and measured after 7 to 10 days |
30925338 |
NB4 |
Antiproliferative assay |
1 to 30 uM |
3 days |
Antiproliferative activity against human NB4 cells assessed as reduction in viability at 1 to 30 uM after 3 days by SRB assay |
30925338 |
HL60 |
Antiproliferative assay |
1 to 30 uM |
3 days |
Antiproliferative activity against human HL60 cells assessed as reduction in viability at 1 to 30 uM after 3 days by SRB assay |
30925338 |
HL60 |
Function assay |
10 to 30 uM |
6 days |
Induction of granulocytic differentiation in human HL60 cells assessed as increase in CD11b-APC-Cy7 positive cells at 10 to 30 uM after 6 days by flow cytometry analysis |
30925338 |
SH-SY5Y |
Function assay |
0.001 to 1 uM |
8 hrs |
Transactivation of RARbeta in human SH-SY5Y cells assessed as increase in CYP26A1 mRNA expression at 0.001 to 1 uM measured after 8 hrs by RT-PCR analysis |
29439915 |
SH-SY5Y |
Function assay |
0.001 to 1 uM |
8 hrs |
Induction of neuronal differentiation in human SH-SY5Y cells assessed as increase in RARbeta mRNA expression at 0.001 to 1 uM measured after 8 hrs by RT-PCR analysis |
29439915 |
SH-SY5Y |
Function assay |
10 uM |
4 to 12 hrs |
Transactivation of RARbeta in human SH-SY5Y cells assessed as increase in CYP26A1 mRNA expression at 10 uM measured after 4 to 12 hrs by RT-PCR analysis |
29439915 |
SH-SY5Y |
Function assay |
10 uM |
4 to 12 hrs |
Induction of neuronal differentiation in human SH-SY5Y cells assessed as increase in RARbeta mRNA expression at 10 uM measured after 4 to 12 hrs by RT-PCR analysis |
29439915 |
TERA2.cl.SP12 |
Function assay |
10 uM |
7 days |
Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as increase in A2B5 expression at 10 uM measured after 7 days by immunofluorescence method |
29439915 |
TERA2.cl.SP12 |
Function assay |
10 uM |
7 days |
Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as effect on A2B5 expression at 10 uM after 7 days by flow cytometric analysis |
29439915 |
TERA2.cl.SP12 |
Function assay |
10 uM |
7 days |
Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as effect on TRA160 expression at 10 uM after 7 days by flow cytometric analysis |
29439915 |
TERA2.cl.SP12 |
Function assay |
10 uM |
7 days |
Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as effect on SSEA3 expression at 10 uM after 7 days by flow cytometric analysis |
29439915 |
SK-N-AS |
Cell cycle assay |
4 uM |
24 hrs |
Cell cycle arrest in human SK-N-AS cells assessed as accumulation at sub-G1 phase at 4 uM after 24 hrs by propidium iodide staining based flow cytometry |
28927789 |
SK-N-AS |
Cell cycle assay |
4 uM |
up to 72 hrs |
Cell cycle arrest in human SK-N-AS cells at 4 uM up to 72 hrs by propidium iodide staining based flow cytometry |
28927789 |
SH-SY5Y |
Function assay |
10 uM |
10 days |
Induction of neuronal differentiation in human SH-SY5Y cells assessed as extensive neurites formation at 10 uM followed by culture medium replacement for every three days for 10 days by inverted-phase microscopic analysis |
28863358 |
HL60 |
Function assay |
0.1 to 10 uM |
5 days |
Induction of cell differentiation in human HL60 cells at 0.1 to 10 uM measured after 5 days by NBT/MTT assay |
26832215 |
HL60 |
Function assay |
0.1 to 10 uM |
3 days |
Induction of cell differentiation in human HL60 cells at 0.1 to 10 uM measured after 3 days by NBT/MTT assay |
26832215 |
NB4 |
Antiproliferative assay |
1 uM |
96 hrs |
Antiproliferative activity against human NB4 cells assessed as decrease in cell viability at 1 uM after 96 hrs by trypan blue exclusion test |
26005022 |
HEK293 |
Function assay |
0.01 to 0.1 uM |
48 hrs |
Agonist activity at RARalpha (unknown origin) expressed in HEK293 cells assessed as transcriptional activation at 0.01 to 0.1 uM after 48 hrs by luciferase reporter gene assay |
25838141 |
HL60 |
Function assay |
0.1 uM |
72 hrs |
Induction of CYP26A1 expression in human HL60 cells at 0.1 uM after 72 hrs |
25684424 |
HL60 |
Function assay |
1 uM |
4 days |
Induction of RAR-mediated differentiation of human HL60 cells at 1 uM after 4 days by NBT assay |
24799257 |
F9 |
Function assay |
0.01 uM |
48 hrs |
Activation of RAR in mouse F9 cells assessed as increase in CYP26A1 mRNA level at 0.01 uM after 48 hrs by RT-PCR analysis |
24799257 |
SH-SY5Y |
Function assay |
10 uM |
6 days |
Induction of cell differentiation in human SH-SY5Y cells assessed as neural-like differentiation at 10 uM after 6 days using beta3-tubulin and NF200 staining by microscopic analysis |
24262378 |
NB4 |
Cell cycle assay |
1 uM |
24 hrs |
Cell cycle arrest in human NB4 cells assessed as increase in accumulation at pre-G1 phase at 1 uM after 24 hrs by FACS analysis |
20491440 |
P19 |
Function assay |
2 to 5 uM |
48 hrs |
Induction of neurite outgrowth in mouse P19 cells at 2 to 5 uM after 48 hrs by crystal violet staining |
19821610 |
U87 |
Function assay |
2 to 5 uM |
48 hrs |
Induction of neurite outgrowth in human U87 cells at 2 to 5 uM after 48 hrs by crystal violet staining |
19821610 |
Neuro2a |
Function assay |
2 to 5 uM |
48 hrs |
Induction of neurite outgrowth in mouse Neuro2a cells at 2 to 5 uM after 48 hrs by crystal violet staining |
19821610 |
SH-SY5Y |
Function assay |
2 to 5 uM |
48 hrs |
Induction of neurite outgrowth in human SH-SY5Y cells at 2 to 5 uM after 48 hrs by crystal violet staining |
19821610 |
SK-N-SH |
Function assay |
2 to 5 uM |
48 hrs |
Induction of neurite outgrowth in human SK-N-SH cells at 2 to 5 uM after 48 hrs by crystal violet staining |
19821610 |
LNCAP |
Antiproliferative assay |
10 uM |
48 hrs |
Antiproliferative activity against human LNCAP cells assessed as maximal effect at 10 uM after 48 hrs by MTT assay |
19375825 |
TERA2.cl.SP12 |
Function assay |
10 uM |
|
Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as increase in TUJ1 expression at 10 uM measured up to 3 weeks by immunofluorescence method |
29439915 |
SH-SY5Y |
Function assay |
10 uM |
|
Induction of neuronal differentiation in human SH-SY5Y cells assessed as decrease in cell proliferation at 10 uM followed by culture medium replacement for every three days for 10 days by inverted-phase microscopic analysis |
28863358 |
COS-7 |
Function assay |
|
24 hrs |
Transactivation of GAL4-fused mouse RARbeta-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assay, EC50=0.0012μM |
30792038 |
COS-7 |
Function assay |
|
24 hrs |
Transactivation of GAL4-fused mouse RARalpha-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assay, EC50=0.0012μM |
30792038 |
COS-7 |
Function assay |
|
24 hrs |
Transactivation of GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assay, EC50=0.0006μM |
30792038 |
COS-7 |
Function assay |
|
1 day |
Transactivation of mouse Gal4-fused RARalpha-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay, EC50=0.00151μM |
29288071 |
HEK293T |
Function assay |
|
16 to 24 hrs |
Transactivation of human Gal4-DBD-fused RARalpha-LBD expressed in HEK293T cells after 16 to 24 hrs by FRET based beta-lactamase reporter gene assay, EC50=0.00101μM |
29288071 |
COS-7 |
Function assay |
|
1 day |
Transactivation of mouse Gal4-fused RARbeta-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay, EC50=0.00052μM |
29288071 |
COS-7 |
Function assay |
|
1 day |
Transactivation of mouse Gal4-fused RARgamma-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay, EC50=0.00022μM |
29288071 |
PC3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay, GI50=12.64μM |
25701251 |
MCF7 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay, GI50=12.39μM |
25701251 |
DU145 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay, GI50=11.64μM |
25701251 |
LNCAP |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human LNCAP cells assessed as reduction in cell viability after 48 hrs by MTT assay, GI50=10.33μM |
25701251 |
MDA-MB-453 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MDA-MB-453 cells assessed as reduction in cell viability after 48 hrs by MTT assay, GI50=9.51μM |
25701251 |
T47D |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human T47D cells assessed as reduction in cell viability after 48 hrs by MTT assay, GI50=0.82μM |
25701251 |
HEK293T |
Function assay |
|
45 mins |
Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis, IC50=28.7μM |
23122865 |
COLO205 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay, IC50=37μM |
20405849 |
MT3 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human MT3 cells after 48 hrs by MTT assay, IC50=14μM |
20405849 |
HT-29 |
Cytotoxicity assay |
|
48 hrs |
Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50=4.3μM |
20405849 |
LNCAP |
Antiproliferative assay |
|
48 hrs |
Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay, IC50=0.5μM |
19375825 |
COS7 |
Function assay |
|
16 hrs |
Activity at human RARalpha ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16 hrs by Gal4 response element-driven luciferase reporter gene assay, EC50=0.017μM |
19058965 |
COS7 |
Function assay |
|
16 hrs |
Activity at human RARbeta ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16 hrs by Gal4 response element-driven luciferase reporter gene assay, EC50=0.012μM |
19058965 |
COS7 |
Function assay |
|
16 hrs |
Activity at human RARgamma ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16 hrs by Gal4 response element-driven luciferase reporter gene assay, EC50=0.0002μM |
19058965 |
MDA-MB-231 |
Growth inhibition assay |
|
5 days |
Growth inhibition of human MDA-MB-231 cells after 5 days by MTT assay, GI50=10.85μM |
18543902 |
PC3 |
Growth inhibition assay |
|
5 days |
Growth inhibition of human PC3 cells after 5 days by MTT assay, GI50=7.6μM |
18543902 |
Raji |
Function assay |
|
48 hrs |
Inhibition of TPA-induced Epstein-Barr virus early antigen activation in Raji cells after 48 hrs, IC50=0.0154μM |
17503850 |
F9 |
Function assay |
|
3 days |
Induction of terminal differentiation in mouse F9 cells assessed by measuring secreted plasminogen activator activity after 3 days, IC50=0.0001μM |
17489579 |
LNCaP |
Growth inhibition assay |
|
6 days |
Growth inhibition of human LNCaP cells after 6 days by MTT assay, IC50=10μM |
15615521 |
PC3 |
Growth inhibition assay |
|
6 days |
Growth inhibition of human PC3 cells after 6 days by MTT assay, IC50=2μM |
15615521 |
MCF7 |
Growth inhibition assay |
|
6 days |
Growth inhibition of human MCF7 cells after 6 days by MTT assay, IC50=0.58μM |
15615521 |
T47D |
Growth inhibition assay |
|
6 days |
Growth inhibition of human T47D cells after 6 days by MTT assay, IC50=0.006μM |
15615521 |
ASK |
Function assay |
|
1 hr |
Induction of morphological transformation of rat ASK cells into astrocytes after 1 hr by light microscopy, ED50=10μM |
2849641 |
AM-38 |
Growth inhibition assay |
|
|
Inhibition of human AM-38 cell growth in a cell viability assay, IC50=40.3084μM |
SANGER |
BT-549 |
Growth inhibition assay |
|
|
Inhibition of human BT-549 cell growth in a cell viability assay, IC50=40.4665μM |
SANGER |
CAL-72 |
Growth inhibition assay |
|
|
Inhibition of human CAL-72 cell growth in a cell viability assay, IC50=39.8973μM |
SANGER |
KYSE-410 |
Growth inhibition assay |
|
|
Inhibition of human KYSE-410 cell growth in a cell viability assay, IC50=39.8734μM |
SANGER |
Calu-6 |
Growth inhibition assay |
|
|
Inhibition of human Calu-6 cell growth in a cell viability assay, IC50=39.87μM |
SANGER |
GOTO |
Growth inhibition assay |
|
|
Inhibition of human GOTO cell growth in a cell viability assay, IC50=39.845μM |
SANGER |
TE-5 |
Growth inhibition assay |
|
|
Inhibition of human TE-5 cell growth in a cell viability assay, IC50=39.2767μM |
SANGER |
P30-OHK |
Growth inhibition assay |
|
|
Inhibition of human P30-OHK cell growth in a cell viability assay, IC50=39.6005μM |
SANGER |
GAMG |
Growth inhibition assay |
|
|
Inhibition of human GAMG cell growth in a cell viability assay, IC50=37.8254μM |
SANGER |
LU-134-A |
Growth inhibition assay |
|
|
Inhibition of human LU-134-A cell growth in a cell viability assay, IC50=36.6391μM |
SANGER |
KS-1 |
Growth inhibition assay |
|
|
Inhibition of human KS-1 cell growth in a cell viability assay, IC50=37.6794μM |
SANGER |
RH-1 |
Growth inhibition assay |
|
|
Inhibition of human RH-1 cell growth in a cell viability assay, IC50=36.1915μM |
SANGER |
SK-MEL-28 |
Growth inhibition assay |
|
|
Inhibition of human SK-MEL-28 cell growth in a cell viability assay, IC50=35.3569μM |
SANGER |
EGI-1 |
Growth inhibition assay |
|
|
Inhibition of human EGI-1 cell growth in a cell viability assay, IC50=35.2918μM |
SANGER |
SK-LU-1 |
Growth inhibition assay |
|
|
Inhibition of human SK-LU-1 cell growth in a cell viability assay, IC50=34.8315μM |
SANGER |
MSTO-211H |
Growth inhibition assay |
|
|
Inhibition of human MSTO-211H cell growth in a cell viability assay, IC50=34.8177μM |
SANGER |
KYSE-510 |
Growth inhibition assay |
|
|
Inhibition of human KYSE-510 cell growth in a cell viability assay, IC50=34.5335μM |
SANGER |
A204 |
Growth inhibition assay |
|
|
Inhibition of human A204 cell growth in a cell viability assay, IC50=34.3531μM |
SANGER |
BALL-1 |
Growth inhibition assay |
|
|
Inhibition of human BALL-1 cell growth in a cell viability assay, IC50=34.0459μM |
SANGER |
Mewo |
Growth inhibition assay |
|
|
Inhibition of human Mewo cell growth in a cell viability assay, IC50=33.8446μM |
SANGER |
NTERA-S-cl-D1 |
Growth inhibition assay |
|
|
Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay, IC50=32.8106μM |
SANGER |
A2780 |
Growth inhibition assay |
|
|
Inhibition of human A2780 cell growth in a cell viability assay, IC50=32.5555μM |
SANGER |
DoTc2-4510 |
Growth inhibition assay |
|
|
Inhibition of human DoTc2-4510 cell growth in a cell viability assay, IC50=31.9219μM |
SANGER |
CCRF-CEM |
Growth inhibition assay |
|
|
Inhibition of human CCRF-CEM cell growth in a cell viability assay, IC50=31.6673μM |
SANGER |
DOHH-2 |
Growth inhibition assay |
|
|
Inhibition of human DOHH-2 cell growth in a cell viability assay, IC50=30.5389μM |
SANGER |
Ramos-2G6-4C10 |
Growth inhibition assay |
|
|
Inhibition of human Ramos-2G6-4C10 cell growth in a cell viability assay, IC50=29.9893μM |
SANGER |
A549 |
Growth inhibition assay |
|
|
Inhibition of human A549 cell growth in a cell viability assay, IC50=29.046μM |
SANGER |
A673 |
Growth inhibition assay |
|
|
Inhibition of human A673 cell growth in a cell viability assay, IC50=28.2446μM |
SANGER |
NCI-H1623 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H1623 cell growth in a cell viability assay, IC50=28.1796μM |
SANGER |
CAMA-1 |
Growth inhibition assay |
|
|
Inhibition of human CAMA-1 cell growth in a cell viability assay, IC50=28.0179μM |
SANGER |
A4-Fuk |
Growth inhibition assay |
|
|
Inhibition of human A4-Fuk cell growth in a cell viability assay, IC50=26.7218μM |
SANGER |
SK-MEL-24 |
Growth inhibition assay |
|
|
Inhibition of human SK-MEL-24 cell growth in a cell viability assay, IC50=26.0032μM |
SANGER |
SK-MEL-1 |
Growth inhibition assay |
|
|
Inhibition of human SK-MEL-1 cell growth in a cell viability assay, IC50=23.4999μM |
SANGER |
LU-139 |
Growth inhibition assay |
|
|
Inhibition of human LU-139 cell growth in a cell viability assay, IC50=23.2003μM |
SANGER |
LB1047-RCC |
Growth inhibition assay |
|
|
Inhibition of human LB1047-RCC cell growth in a cell viability assay, IC50=23.0132μM |
SANGER |
JVM-3 |
Growth inhibition assay |
|
|
Inhibition of human JVM-3 cell growth in a cell viability assay, IC50=22.9733μM |
SANGER |
UM-UC-3 |
Growth inhibition assay |
|
|
Inhibition of human UM-UC-3 cell growth in a cell viability assay, IC50=22.677μM |
SANGER |
23132-87 |
Growth inhibition assay |
|
|
Inhibition of human 23132-87 cell growth in a cell viability assay, IC50=40.541μM |
SANGER |
CAKI-1 |
Growth inhibition assay |
|
|
Inhibition of human CAKI-1 cell growth in a cell viability assay, IC50=22.169μM |
SANGER |
CHL-1 |
Growth inhibition assay |
|
|
Inhibition of human CHL-1 cell growth in a cell viability assay, IC50=22.1242μM |
SANGER |
KYSE-450 |
Growth inhibition assay |
|
|
Inhibition of human KYSE-450 cell growth in a cell viability assay, IC50=21.8431μM |
SANGER |
J-RT3-T3-5 |
Growth inhibition assay |
|
|
Inhibition of human J-RT3-T3-5 cell growth in a cell viability assay, IC50=21.8087μM |
SANGER |
SW13 |
Growth inhibition assay |
|
|
Inhibition of human SW13 cell growth in a cell viability assay, IC50=21.4558μM |
SANGER |
KNS-42 |
Growth inhibition assay |
|
|
Inhibition of human KNS-42 cell growth in a cell viability assay, IC50=20.7488μM |
SANGER |
SK-N-AS |
Growth inhibition assay |
|
|
Inhibition of human SK-N-AS cell growth in a cell viability assay, IC50=20.4937μM |
SANGER |
COLO-829 |
Growth inhibition assay |
|
|
Inhibition of human COLO-829 cell growth in a cell viability assay, IC50=20.3353μM |
SANGER |
OAW-28 |
Growth inhibition assay |
|
|
Inhibition of human OAW-28 cell growth in a cell viability assay, IC50=20.3321μM |
SANGER |
KG-1 |
Growth inhibition assay |
|
|
Inhibition of human KG-1 cell growth in a cell viability assay, IC50=19.8775μM |
SANGER |
ME-180 |
Growth inhibition assay |
|
|
Inhibition of human ME-180 cell growth in a cell viability assay, IC50=19.8713μM |
SANGER |
HuO9 |
Growth inhibition assay |
|
|
Inhibition of human HuO9 cell growth in a cell viability assay, IC50=19.3158μM |
SANGER |
ES3 |
Growth inhibition assay |
|
|
Inhibition of human ES3 cell growth in a cell viability assay, IC50=18.8495μM |
SANGER |
HSC-3 |
Growth inhibition assay |
|
|
Inhibition of human HSC-3 cell growth in a cell viability assay, IC50=18.7211μM |
SANGER |
HC-1 |
Growth inhibition assay |
|
|
Inhibition of human HC-1 cell growth in a cell viability assay, IC50=18.4345μM |
SANGER |
697 |
Growth inhibition assay |
|
|
Inhibition of human 697 cell growth in a cell viability assay, IC50=17.899μM |
SANGER |
COLO-684 |
Growth inhibition assay |
|
|
Inhibition of human COLO-684 cell growth in a cell viability assay, IC50=16.9273μM |
SANGER |
NCI-H82 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H82 cell growth in a cell viability assay, IC50=16.9221μM |
SANGER |
NCI-H1770 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H1770 cell growth in a cell viability assay, IC50=16.9058μM |
SANGER |
P12-ICHIKAWA |
Growth inhibition assay |
|
|
Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay, IC50=16.493μM |
SANGER |
DEL |
Growth inhibition assay |
|
|
Inhibition of human DEL cell growth in a cell viability assay, IC50=15.3728μM |
SANGER |
NCI-H1092 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H1092 cell growth in a cell viability assay, IC50=15.2894μM |
SANGER |
KMOE-2 |
Growth inhibition assay |
|
|
Inhibition of human KMOE-2 cell growth in a cell viability assay, IC50=14.7887μM |
SANGER |
HCC1419 |
Growth inhibition assay |
|
|
Inhibition of human HCC1419 cell growth in a cell viability assay, IC50=15.2519μM |
SANGER |
MS-1 |
Growth inhibition assay |
|
|
Inhibition of human MS-1 cell growth in a cell viability assay, IC50=14.5539μM |
SANGER |
IGROV-1 |
Growth inhibition assay |
|
|
Inhibition of human IGROV-1 cell growth in a cell viability assay, IC50=13.1381μM |
SANGER |
NCI-H292 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H292 cell growth in a cell viability assay, IC50=12.2072μM |
SANGER |
NOMO-1 |
Growth inhibition assay |
|
|
Inhibition of human NOMO-1 cell growth in a cell viability assay, IC50=11.9634μM |
SANGER |
CHP-212 |
Growth inhibition assay |
|
|
Inhibition of human CHP-212 cell growth in a cell viability assay, IC50=10.8494μM |
SANGER |
KE-37 |
Growth inhibition assay |
|
|
Inhibition of human KE-37 cell growth in a cell viability assay, IC50=10.7515μM |
SANGER |
HCC2218 |
Growth inhibition assay |
|
|
Inhibition of human HCC2218 cell growth in a cell viability assay, IC50=10.3872μM |
SANGER |
GP5d |
Growth inhibition assay |
|
|
Inhibition of human GP5d cell growth in a cell viability assay, IC50=10.2637μM |
SANGER |
NCI-H1648 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H1648 cell growth in a cell viability assay, IC50=9.73617μM |
SANGER |
MEG-01 |
Growth inhibition assay |
|
|
Inhibition of human MEG-01 cell growth in a cell viability assay, IC50=9.61318μM |
SANGER |
SCC-15 |
Growth inhibition assay |
|
|
Inhibition of human SCC-15 cell growth in a cell viability assay, IC50=9.34762μM |
SANGER |
NKM-1 |
Growth inhibition assay |
|
|
Inhibition of human NKM-1 cell growth in a cell viability assay, IC50=8.41009μM |
SANGER |
NCI-H526 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H526 cell growth in a cell viability assay, IC50=7.68291μM |
SANGER |
EW-13 |
Growth inhibition assay |
|
|
Inhibition of human EW-13 cell growth in a cell viability assay, IC50=7.61078μM |
SANGER |
BPH-1 |
Growth inhibition assay |
|
|
Inhibition of human BPH-1 cell growth in a cell viability assay, IC50=7.43611μM |
SANGER |
A3-KAW |
Growth inhibition assay |
|
|
Inhibition of human A3-KAW cell growth in a cell viability assay, IC50=7.59637μM |
SANGER |
NB14 |
Growth inhibition assay |
|
|
Inhibition of human NB14 cell growth in a cell viability assay, IC50=7.1271μM |
SANGER |
ALL-PO |
Growth inhibition assay |
|
|
Inhibition of human ALL-PO cell growth in a cell viability assay, IC50=6.8745μM |
SANGER |
KYSE-180 |
Growth inhibition assay |
|
|
Inhibition of human KYSE-180 cell growth in a cell viability assay, IC50=6.7014μM |
SANGER |
QIMR-WIL |
Growth inhibition assay |
|
|
Inhibition of human QIMR-WIL cell growth in a cell viability assay, IC50=6.6155μM |
SANGER |
KY821 |
Growth inhibition assay |
|
|
Inhibition of human KY821 cell growth in a cell viability assay, IC50=5.70426μM |
SANGER |
EM-2 |
Growth inhibition assay |
|
|
Inhibition of human EM-2 cell growth in a cell viability assay, IC50=5.32811μM |
SANGER |
DB |
Growth inhibition assay |
|
|
Inhibition of human DB cell growth in a cell viability assay, IC50=4.76519μM |
SANGER |
RS4-11 |
Growth inhibition assay |
|
|
Inhibition of human RS4-11 cell growth in a cell viability assay, IC50=4.44737μM |
SANGER |
U-266 |
Growth inhibition assay |
|
|
Inhibition of human U-266 cell growth in a cell viability assay, IC50=4.11829μM |
SANGER |
ML-2 |
Growth inhibition assay |
|
|
Inhibition of human ML-2 cell growth in a cell viability assay, IC50=4.00439μM |
SANGER |
COR-L88 |
Growth inhibition assay |
|
|
Inhibition of human COR-L88 cell growth in a cell viability assay, IC50=3.85872μM |
SANGER |
KARPAS-45 |
Growth inhibition assay |
|
|
Inhibition of human KARPAS-45 cell growth in a cell viability assay, IC50=2.59581μM |
SANGER |
NCI-H209 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H209 cell growth in a cell viability assay, IC50=2.52132μM |
SANGER |
ECC10 |
Growth inhibition assay |
|
|
Inhibition of human ECC10 cell growth in a cell viability assay, IC50=2.38052μM |
SANGER |
NCI-H69 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H69 cell growth in a cell viability assay, IC50=2.26561μM |
SANGER |
L-363 |
Growth inhibition assay |
|
|
Inhibition of human L-363 cell growth in a cell viability assay, IC50=2.06964μM |
SANGER |
CTB-1 |
Growth inhibition assay |
|
|
Inhibition of human CTB-1 cell growth in a cell viability assay, IC50=1.60389μM |
SANGER |
ACN |
Growth inhibition assay |
|
|
Inhibition of human ACN cell growth in a cell viability assay, IC50=1.64999μM |
SANGER |
BV-173 |
Growth inhibition assay |
|
|
Inhibition of human BV-173 cell growth in a cell viability assay, IC50=1.59626μM |
SANGER |
JVM-2 |
Growth inhibition assay |
|
|
Inhibition of human JVM-2 cell growth in a cell viability assay, IC50=1.17316μM |
SANGER |
NBsusSR |
Growth inhibition assay |
|
|
Inhibition of human NBsusSR cell growth in a cell viability assay, IC50=1.44987μM |
SANGER |
MOLT-13 |
Growth inhibition assay |
|
|
Inhibition of human MOLT-13 cell growth in a cell viability assay, IC50=1.145μM |
SANGER |
NCI-H720 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H720 cell growth in a cell viability assay, IC50=1.02621μM |
SANGER |
LAMA-84 |
Growth inhibition assay |
|
|
Inhibition of human LAMA-84 cell growth in a cell viability assay, IC50=0.99635μM |
SANGER |
RPMI-8226 |
Growth inhibition assay |
|
|
Inhibition of human RPMI-8226 cell growth in a cell viability assay, IC50=0.99334μM |
SANGER |
CTV-1 |
Growth inhibition assay |
|
|
Inhibition of human CTV-1 cell growth in a cell viability assay, IC50=0.96282μM |
SANGER |
HCC1806 |
Growth inhibition assay |
|
|
Inhibition of human HCC1806 cell growth in a cell viability assay, IC50=0.72929μM |
SANGER |
HuO-3N1 |
Growth inhibition assay |
|
|
Inhibition of human HuO-3N1 cell growth in a cell viability assay, IC50=0.8316μM |
SANGER |
SK-NEP-1 |
Growth inhibition assay |
|
|
Inhibition of human SK-NEP-1 cell growth in a cell viability assay, IC50=0.66231μM |
SANGER |
KU812 |
Growth inhibition assay |
|
|
Inhibition of human KU812 cell growth in a cell viability assay, IC50=0.53609μM |
SANGER |
EW-3 |
Growth inhibition assay |
|
|
Inhibition of human EW-3 cell growth in a cell viability assay, IC50=0.48028μM |
SANGER |
HL-60 |
Growth inhibition assay |
|
|
Inhibition of human HL-60 cell growth in a cell viability assay, IC50=0.28491μM |
SANGER |
D-283MED |
Growth inhibition assay |
|
|
Inhibition of human D-283MED cell growth in a cell viability assay, IC50=0.28262μM |
SANGER |
NB13 |
Growth inhibition assay |
|
|
Inhibition of human NB13 cell growth in a cell viability assay, IC50=0.25664μM |
SANGER |
HH |
Growth inhibition assay |
|
|
Inhibition of human HH cell growth in a cell viability assay, IC50=0.19554μM |
SANGER |
ATN-1 |
Growth inhibition assay |
|
|
Inhibition of human ATN-1 cell growth in a cell viability assay, IC50=0.0303μM |
SANGER |
MC-IXC |
Growth inhibition assay |
|
|
Inhibition of human MC-IXC cell growth in a cell viability assay, IC50=0.15436μM |
SANGER |
MV-4-11 |
Growth inhibition assay |
|
|
Inhibition of human MV-4-11 cell growth in a cell viability assay, IC50=0.02099μM |
SANGER |
CV-1 |
Function assay |
|
|
Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor beta using transactivation assay, EC50=1.4μM |
ChEMBL |
CV-1 |
Function assay |
|
|
Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor gamma using transactivation assay, EC50=1.1μM |
ChEMBL |
CV-1 |
Function assay |
|
|
Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor alpha using transactivation assay, EC50=0.9μM |
ChEMBL |
F9 |
Function assay |
|
|
Cellular activity on the differentiation was quantified by measure of plasminogen activator in mouse embryonal teratocarcinoma F9 cells, AC50=0.2μM |
ChEMBL |
CV-1 |
Function assay |
|
|
Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor alpha using transactivation assay, EC50=0.007μM |
ChEMBL |
CV-1 |
Function assay |
|
|
Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor beta using transactivation assay, EC50=0.001μM |
ChEMBL |
CV-1 |
Function assay |
|
|
Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor gamma using transactivation assay, EC50=0.0007μM |
ChEMBL |
OHS-50 |
qHTS assay |
|
|
qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells |
29435139 |
LNCAP |
Growth inhibition assay |
|
|
Growth inhibition of human LNCAP cells by MTT assay, GI50=47.86μM |
25634130 |
PC3 |
Growth inhibition assay |
|
|
Growth inhibition of human PC3 cells by MTT assay, GI50=36.3μM |
25634130 |
CWR22Rv1 |
Growth inhibition assay |
|
|
Growth inhibition of human CWR22Rv1 cells by MTT assay, GI50=25.11μM |
25634130 |
SKBR3 |
Growth inhibition assay |
|
|
Growth inhibition of human SKBR3 cells by MTT assay, GI50=22.9μM |
25634130 |
MDA-MB-468 |
Growth inhibition assay |
|
|
Growth inhibition of human MDA-MB-468 cells by MTT assay, GI50=14.12μM |
25634130 |
MDA-MB-231 |
Growth inhibition assay |
|
|
Growth inhibition of human MDA-MB-231 cells by MTT assay, GI50=14.12μM |
25634130 |
BL-21 (BL3) |
Function assay |
|
|
Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitment, EC50=18μM |
24502334 |
NIH3T3 |
Function assay |
|
|
Activity at RARgamma expressed in mouse NIH3T3 cells by R-SAT assay, EC50=0.05012μM |
19239230 |
NIH3T3 |
Function assay |
|
|
Activity at RARbeta1 expressed in mouse NIH3T3 cells by R-SAT assay, EC50=0.02512μM |
19239230 |
NIH3T3 |
Function assay |
|
|
Activity at RARalpha expressed in mouse NIH3T3 cells by R-SAT assay, EC50=0.00631μM |
19239230 |
NIH3T3 |
Function assay |
|
|
Agonist activity at RARbeta2 expressed in mouse NIH3T3 cells by R-SAT assay, EC50=0.00631μM |
19239230 |
HaCaT |
Function assay |
|
|
Increase in transcriptional activity of RARalpha receptor epressed in human HaCaT cells co-transfected with DR5-tk-CAT reporter plasmid assessed as beta-galactosidase activity by CAT-ELISA |
18511283 |
MCF7 |
Antiproliferative assay |
|
|
Antiproliferative effect against human MCF7 cells, IC50=0.5845μM |
15615521 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing mouse Retinoid X receptor RXR beta, EC50=1.211μM |
12482435 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing human Retinoid X receptor RXR-alpha, EC50=1.015μM |
12482435 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing mouse Retinoid X receptor RXR gamma, EC50=0.961μM |
12482435 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR alpha, EC50=0.436μM |
12482435 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR beta, EC50=0.078μM |
12482435 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR gamma, EC50=0.019μM |
12482435 |
HL60 |
Function assay |
|
|
In vitro cytotoxicity against HL60 cells, IC50=11μM |
11128648 |
COS |
Function assay |
|
|
Transcriptional activation in COS cells expressing RAR-alpha, Relative EC30=0.0034μM |
10956201 |
COS |
Function assay |
|
|
Transcriptional activation in COS cells expressing RAR-beta, Relative EC30=0.0022μM |
10956201 |
COS |
Function assay |
|
|
Transcriptional activation in COS cells expressing RAR-gamma, Relative EC30=0.00026μM |
10956201 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing RAR alpha receptor, EC30=0.0011μM |
10762039 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing RAR beta receptor, EC30=0.00069μM |
10762039 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing RAR gamma receptor, EC30=0.00018μM |
10762039 |
CV-1 |
Function assay |
|
|
Relative transcriptional activation in CV-1 cells expressing RAR gamma receptor compared to ATRA, Relative EC30=0.001μM |
10762038 |
CV-1 |
Function assay |
|
|
Relative transcriptional activation in CV-1 cells expressing RAR beta receptor compared to ATRA, Relative EC30=0.001μM |
10762038 |
CV-1 |
Function assay |
|
|
Relative transcriptional activation in CV-1 cells expressing RAR alpha receptor compared to ATRA, Relative EC30=0.001μM |
10762038 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing RAR alpha receptor, EC30=0.00099μM |
10762038 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing RAR beta receptor, EC30=0.00093μM |
10762038 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing RAR gamma receptor, EC30=0.00022μM |
10762038 |
HL-60 |
Function assay |
|
|
Induction of HL-60 cells differentiation over 4 days, ED50=0.12μM |
9572893 |
HL-60 |
Cytostatic assay |
|
|
Cytostatic activity against HL-60 cells, IC50=11μM |
10585206 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR alpha, EC50=0.022μM |
9572893 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gamma, EC50=0.006μM |
9572893 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR beta, EC50=0.002μM |
9572893 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alpha, EC50=0.459μM |
8978832 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR beta, EC50=0.087μM |
8978832 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gamma, EC50=0.02μM |
8978832 |
embryonic limb bud cells |
Function assay |
|
|
Inhibition of Chondrogenesis in day 11 embryonic limb bud cells, IC50=0.031μM |
8784454 |
HL-60 |
Function assay |
|
|
Induction of transglutaminase (TGase) activity in HL-60 cells, EC50=0.005μM |
8784454 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR beta, EC50=1.394μM |
8709094 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR gamma, EC50=1.225μM |
8709094 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR alpha, EC50=1.084μM |
8709094 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alpha, EC50=0.563μM |
8709094 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR beta, EC50=0.105μM |
8709094 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gamma, EC50=0.033μM |
8709094 |
F9 |
Function assay |
|
|
In vitro promotion of plasminogen activator secretion from F9 (murine teratocarcinoma) cells, AC50=0.2μM |
8544175 |
CV-1 |
Function assay |
|
|
Binding affinity against retinoic Acid X beta receptors co-transfected into CV-1 cells, EC50=1.4μM |
8308867 |
CV-1 |
Function assay |
|
|
Binding affinity against retinoic Acid X gamma receptors co-transfected into CV-1 cells, EC50=1.1μM |
8308867 |
CV-1 |
Function assay |
|
|
Binding affinity against retinoic Acid X alpha receptors co-transfected into CV-1 cells, EC50=0.9μM |
8308867 |
CV-1 |
Function assay |
|
|
Binding affinity against retinoic Acid alpha receptors co-transfected into CV-1 cells, EC50=0.35μM |
8308867 |
CV-1 |
Function assay |
|
|
Binding affinity against retinoic Acid beta receptors co-transfected into CV-1 cells, EC50=0.08μM |
8308867 |
CV-1 |
Function assay |
|
|
Binding affinity against retinoic Acid gamma receptors co-transfected into CV-1 cells, EC50=0.01μM |
8308867 |
leukemia cells |
Function assay |
|
|
The concentration required to inhibit the binding of [3H]ATRA to retinoic acid receptor in human promyelocytic leukemia cells, IC50=0.00063μM |
7636879 |
mouse embryo limb bud cells |
Function assay |
|
|
In vitro inhibition of chondrogenesis in mouse embryo limb bud cells, IC50=0.031μM |
7636843 |
HL-60 cdm-1 |
Function assay |
|
|
Transglutaminase activity in HL-60 cdm-1 cells, EC50=0.005μM |
7636843 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alpha, EC50=0.007μM |
7490725 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR beta, EC50=0.001μM |
7490725 |
CV-1 |
Function assay |
|
|
Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gamma, EC50=0.0007μM |
7490725 |
F9 |
Function assay |
|
|
Ability to displace [3H]all-trans-retinoic acid from F9 embryonal carcinoma cells, was assessed in a F9 laminin release assay, ED50=0.0015μM |
2738885 |
F9 |
Function assay |
|
|
Ability to displace 3 uM retinoid and [3H]all-trans-retinoic acid in F9 embryonal carcinoma cells using F9 Plasminogen Activator releasing assay, ED50=0.0001μM |
2738885 |
T-47D cells |
Proliferation assay |
|
|
Inhibition of ER positive human breast cancer cell T-47D proliferation, IC50=0.2 μM |
12372520 |
human breast cancer cell SK-BR-3 |
Proliferation assay |
|
|
Inhibition of ER-negative human breast cancer cell SK-BR-3 proliferation, IC50=0.0017 μM |
12372520 |
SCC-4 |
Growth inhibition assay |
|
|
Inhibition of human SCC-4 cell growth in a cell viability assay, IC50=40.9788μM |
SANGER |
LU-135 |
Growth inhibition assay |
|
|
Inhibition of human LU-135 cell growth in a cell viability assay, IC50=41.0418μM |
SANGER |
NB10 |
Growth inhibition assay |
|
|
Inhibition of human NB10 cell growth in a cell viability assay, IC50=41.4859μM |
SANGER |
NB7 |
Growth inhibition assay |
|
|
Inhibition of human NB7 cell growth in a cell viability assay, IC50=41.6004μM |
SANGER |
RPMI-7951 |
Growth inhibition assay |
|
|
Inhibition of human RPMI-7951 cell growth in a cell viability assay, IC50=41.6006μM |
SANGER |
AU565 |
Growth inhibition assay |
|
|
Inhibition of human AU565 cell growth in a cell viability assay, IC50=41.7522μM |
SANGER |
HCE-4 |
Growth inhibition assay |
|
|
Inhibition of human HCE-4 cell growth in a cell viability assay, IC50=42.548μM |
SANGER |
BE-13 |
Growth inhibition assay |
|
|
Inhibition of human BE-13 cell growth in a cell viability assay, IC50=42.5818μM |
SANGER |
LCLC-103H |
Growth inhibition assay |
|
|
Inhibition of human LCLC-103H cell growth in a cell viability assay, IC50=42.8462μM |
SANGER |
NCI-H2126 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H2126 cell growth in a cell viability assay, IC50=43.1561μM |
SANGER |
PA-1 |
Growth inhibition assay |
|
|
Inhibition of human PA-1 cell growth in a cell viability assay, IC50=43.7456μM |
SANGER |
HSC-4 |
Growth inhibition assay |
|
|
Inhibition of human HSC-4 cell growth in a cell viability assay, IC50=44.5506μM |
SANGER |
DMS-79 |
Growth inhibition assay |
|
|
Inhibition of human DMS-79 cell growth in a cell viability assay, IC50=45.7028μM |
SANGER |
EKVX |
Growth inhibition assay |
|
|
Inhibition of human EKVX cell growth in a cell viability assay, IC50=45.9377μM |
SANGER |
NOS-1 |
Growth inhibition assay |
|
|
Inhibition of human NOS-1 cell growth in a cell viability assay, IC50=46.2764μM |
SANGER |
U-118-MG |
Growth inhibition assay |
|
|
Inhibition of human U-118-MG cell growth in a cell viability assay, IC50=46.3314μM |
SANGER |
Daoy |
Growth inhibition assay |
|
|
Inhibition of human Daoy cell growth in a cell viability assay, IC50=47.4651μM |
SANGER |
SBC-1 |
Growth inhibition assay |
|
|
Inhibition of human SBC-1 cell growth in a cell viability assay, IC50=47.5218μM |
SANGER |
CAL-51 |
Growth inhibition assay |
|
|
Inhibition of human CAL-51 cell growth in a cell viability assay, IC50=47.6001μM |
SANGER |
NY |
Growth inhibition assay |
|
|
Inhibition of human NY cell growth in a cell viability assay, IC50=48.7628μM |
SANGER |
BxPC-3 |
Growth inhibition assay |
|
|
Inhibition of human BxPC-3 cell growth in a cell viability assay, IC50=48.8002μM |
SANGER |
MOLT-16 |
Growth inhibition assay |
|
|
Inhibition of human MOLT-16 cell growth in a cell viability assay, IC50=49.2304μM |
SANGER |
NCI-H1155 |
Growth inhibition assay |
|
|
Inhibition of human NCI-H1155 cell growth in a cell viability assay, IC50=49.9855μM |
SANGER |