ASK1 选择性抑制剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S0067	GS-444217	GS-444217 (ASK1-IN-1) is a potent, selective, orally available and ATP-competitive inhibitor of ASK1 (apoptosis signal-regulating kinase 1) with IC50 of 2.87 nM.	Selective	ASK1, IC50: 2.87 nM
S8292	Selonsertib (GS-4997)	Selonsertib (GS-4997) is a highly selective and potent once-daily oral ASK1 inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.	Selective	ASK1, pIC50: 8.3
S8289	NQDI-1	NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic renal injury by modulating oxidative stress and cell death.	Selective	ASK1, IC50: 3 μM