CDK1
CDK2
CDK3
CDK4
CDK5
CDK6
CDK7
CDK9
CLK
Cdc
CDK8
CDK12
CDK13
CDK19
CDK11
CDK/cyclin complexes

CDK11 选择性抑制剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S7648	OTS964	OTS964 is a potent TOPK inhibitor with high affinity and selectivity and IC50 value is 28 nM. OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11 with Kd of 40 nM. OTS964 treatment activates autophagy in glioma cells and induces apoptosis of human lung cancer cells in mouse xenografts.	Selective	CDK11B, Kd: 40 nM