- CXCR1
- CXCR2
- CXCR4
- CXCR3
CXCR3 选择性拮抗剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S8682 | AMG 487 | AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8.0 nM and 8.2 nM, respectively. | Selective | CXCR3-CXCL10, IC50: 8.0 nM; CXCR3-CXCL11, IC50: 8.2 nM |
