DYRK1
DYRK2
DYRK3

DYRK2 选择性抑制剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S3406	LDN-192960	LDN-192960 (Compd 1) is a potent inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50 of 10 nM and 48 nM, respectively.	Selective	DYRK2, IC50: 48 nM
S3817	Harmine hydrochloride	Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγ and cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptor with Ki of 397 nM.	Pan	DYRK2, IC50: 1.9 μM