MALT1 选择性抑制剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S9896	Safimaltib	Safimaltib(JNJ-67856633,JNJ-6633) is a potent, selective, allosteric inhibitor of MALT1 protease.	Selective
S8898	MLT-748	MLT-748 is a potent, selective and allosteric inhibitor of MALT1 with IC50 of 5 nM, binding at the interface between the caspase and immunoglobulin (Ig3) domains by displacing Trp580 and locking the catalytic site in an inactive state.	Selective	MALT1, IC50: 5 nM
S7429	MI-2 (MALT1 inhibitor)	MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor with IC50 of 5.84 μM.	Selective	MALT1, IC50: 5.84 μM