MAP4K2
MAP4K4
MAP4K6
MAP4K7

MAP4K7 选择性抑制剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S8392	NCB-0846	NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase, MAP4K7) with an IC50 value of 21 nM.	Selective	TNIK, IC50: 21 nM
S0268	DMX-5084	DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.	Pan	TNIK/MAP4K7, pIC50: 7.96