| S0342 |
Atopaxar |
Atopaxar(E5555,ER-172594-00) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. |
Selective |
|
| S8067 |
Vorapaxar (MK-5348) |
Vorapaxar (SCH 530348, MK-5348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM. |
Selective |
PAR-1, Ki: 8.1 nM |
| S9916 |
SCH79797 dihydrochloride |
SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist, which can inhibit binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM. |
Selective |
PAR1, IC50: 70 nM |
| S2916 |
ML161 (Parmodulin 2) |
ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM. |
Selective |
PAR1, IC50: 0.26 μM |
