| S8393 |
HG-9-91-01 |
HG-9-91-01 (SIK inhibitor 1) is a potent and highly selective inhibitor of salt-inducible kinase (SIK) with IC50 of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3, respectively. |
Pan |
SIK1, IC50: 0.92 nM |
| S0051 |
YKL 06-061 |
YKL 06-061 is a potent and selective salt-inducible kinase (SIK) inhibitor with IC50 of 6.56 nM, 1.77 nM and 20.5 nM for SIK1, SIK2 and SIK3, respectively. |
Pan |
SIK1, IC50: 6.56 nM |
| S9646 |
YKL-05-099 |
YKL-05-099 is an inhibitor of salt-inducible kinase (SIK) with IC50 of ~10 nM, ~40 nM and ~30 nM for SIK1, SIK2 and SIK3, respectively. |
Pan |
SIK1, IC50: 10 nM |
| S8543 |
ARN-3236 |
ARN-3236 is a potent, orally available and selective inhibitor of salt-inducible kinase 2 (SIK2) with IC50 of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. ARN-3236 induces apoptosis in cancer cells. |
Pan |
SIK1, IC50: 21.63 nM |
