- SIRT1
- SIRT2
- SIRT3
- SIRT6
- SIRT5
SIRT3 抑制剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S8628 | 3-TYP | 3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor which is selective for Sirt3 over Sirt1 and Sirt2. The IC50 values for SITR1, SIRT2, SIRT3 are 88 nM, 92 nM, 16 nM respectively. | Pan | SIRT3, IC50: 16 nM |
| S4900 | Tenovin-6 | Tenovin-6 is a small molecule activator of p53 transcriptional activity and inhibits dihydroorotate dehydrogenase (DHODH). Tenovin-6 is also an inhibitor of SirT1 and SirT2. | Pan | SIRT3, IC50: 67 μM |
