PTEN

PTEN产品

• 所有产品(7)
• PTEN抑制剂 (3)
• PTEN抗体 (1)
• PTEN激活剂 (2)
• 新PTEN产品

目录号	产品名	产品描述	文献引用	实验数据
S7310	SF1670	SF1670是一种高度有效且专一的PTEN的抑制剂，其IC50 为 2 μM。	J Biol Chem, 2024, S0021-9258(24)01808-8 Fish Shellfish Immunol, 2024, 146:109384 eNeuro, 2023, 10(9)ENEURO.0185-23.2023
S8651	bpV (HOpic)	bpV (HOpic) (Bisperoxovanadium (HOpic))是一种有效的PTEN抑制剂，IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。	Cell Rep, 2024, 43(4):114005 Res Sq, 2024, rs.3.rs-4603170 Protein Cell, 2023, 14(5):350-368
S8174	VO-Ohpic trihydrate	VO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂，IC50为35 nM。	Nature, 2024, 631(8019):170-178 Aging (Albany NY), 2023, 15(6):2275-2292 Stem Cell Res Ther, 2020, 11(1):140
S9190	Oroxin B	Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.	Environ Pollut, 2023, 323:121306 Theranostics, 2022, 12(2):910-928 J Cancer, 2021, 12(7):2140-2150
S0918	Ginkgolic acid C17:1	Ginkgolic acid C17:1 (GAC 17:1) 通过废除上游的 JAK2 和 Src 来抑制 STAT3 的组成性激活。Ginkgolic acid C17:1 可以诱导 PTEN 和 SHP-1 的大量表达。Ginkgolic acid C17:1 诱导肿瘤细胞凋亡。
A5040	PTEN Rabbit Recombinant mAb	PTEN Antibody detects endogenous levels of PTEN.
F0499New	Phospho-PTEN (Ser380/Thr382/383) Rabbit mAb	Phospho-PTEN (Ser380),Phospho-PTEN (Ser380/Thr382/383),PTEN (phospho S380)
S7310	SF1670	SF1670是一种高度有效且专一的PTEN的抑制剂，其IC50 为 2 μM。	J Biol Chem, 2024, S0021-9258(24)01808-8 Fish Shellfish Immunol, 2024, 146:109384 eNeuro, 2023, 10(9)ENEURO.0185-23.2023
S8651	bpV (HOpic)	bpV (HOpic) (Bisperoxovanadium (HOpic))是一种有效的PTEN抑制剂，IC50为14 nM。它对PTP-β和PTP-1B的IC50值分别约是对PTEN的IC50的350倍和1800倍。	Cell Rep, 2024, 43(4):114005 Res Sq, 2024, rs.3.rs-4603170 Protein Cell, 2023, 14(5):350-368
S8174	VO-Ohpic trihydrate	VO-Ohpic是一种有效的PTEN (phosphatase and tensin homolog)抑制剂，IC50为35 nM。	Nature, 2024, 631(8019):170-178 Aging (Albany NY), 2023, 15(6):2275-2292 Stem Cell Res Ther, 2020, 11(1):140
A5040	PTEN Rabbit Recombinant mAb	PTEN Antibody detects endogenous levels of PTEN.
S9190	Oroxin B	Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.	Environ Pollut, 2023, 323:121306 Theranostics, 2022, 12(2):910-928 J Cancer, 2021, 12(7):2140-2150
S0918	Ginkgolic acid C17:1	Ginkgolic acid C17:1 (GAC 17:1) 通过废除上游的 JAK2 和 Src 来抑制 STAT3 的组成性激活。Ginkgolic acid C17:1 可以诱导 PTEN 和 SHP-1 的大量表达。Ginkgolic acid C17:1 诱导肿瘤细胞凋亡。
F0499New	Phospho-PTEN (Ser380/Thr382/383) Rabbit mAb	Phospho-PTEN (Ser380),Phospho-PTEN (Ser380/Thr382/383),PTEN (phospho S380)