S1466 |
Calcitriol
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Calcitriol作为vitamin D的激素活性形式,是一种非选择性vitamin D receptor的激活剂,对vitamin D receptor的结合亲和力(IC50=0.4 nM)是选择性VDRA paricalcitol的10倍以上。在溶液中不稳定,请现配现用! |
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Redox Biol, 2024, 70:103062
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bioRxiv, 2024,
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Cells, 2023, 12(18)2291
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S1469 |
Calcifediol
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Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol)是vitamin D3的主要循环代谢产物,是竞争性抑制剂,表观Ki值为3.9 μM,也抑制PTH分泌和mRNA(ED50为2 nM)。 |
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Front Pharmacol, 2023, 14:1135516
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FEBS Open Bio, 2023, 13(9):1789-1806
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FEBS Open Bio, 2023, 13(9):1789-1806
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S3114 |
Vitamin C
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Vitamin C (L-Ascorbic acid) 是一种水溶性维生素,用于预防和治疗坏血病。 |
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Nat Commun, 2024, 15(1):2384
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Cell Mol Life Sci, 2024, 81(1):92
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Zool Res, 2024, 45(2):233-241
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S1468 |
Alfacalcidol
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Alfacalcidol (1-hydroxycholecalciferol)是非选择性VDR激活剂。 |
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Front Cell Dev Biol, 2024, 12:1384423
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Front Cell Dev Biol, 2024, 12:1384423
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Cell Rep Methods, 2023, 3(10):100599
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S6104 |
(±)-α-Tocopherol
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(±)-α-Tocopherol是维生素E的生物活性形式。维生素E是脂溶性抗氧化剂,可保护细胞膜免受氧化损伤。 |
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Cell Death Differ, 2023, 30(8):1988-2004
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Antioxidants (Basel), 2023, 12(12)2119
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CNS Neurosci Ther, 2022, 28(6):964-970
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S3665 |
Trolox
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Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. |
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Biochemistry, 2024, 63(8):984-999
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Redox Biol, 2023, 65:102825
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Cell Death Dis, 2023, 14(8):515
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S3739 |
Calcipotriene (MC903)
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Calcipotriene (MC903)是calcitriol的合成衍生物,可以诱导角质细胞的分化,抑制其增殖,逆转牛皮癣中角质细胞的异常变化,促使表皮正常生长。在溶液中不稳定,请现配现用! |
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Nutrients, 2024, 16(17)3021
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Pharmaceutics, 2023, 15(2)576
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Pharmaceutics, 2023, 15(2)576
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S1467 |
Doxercalciferol
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Doxercalciferol (1α-hydroxyvitamin D2) 是一种合成的vitamin D类似物。 |
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FEBS Open Bio, 2023, 13(9):1789-1806
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FEBS Open Bio, 2023, 13(9):1789-1806
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Int J Mol Sci, 2022, 23(16)9366
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S1902 |
Vitamin B12
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Vitamin B12 (Cobalamin, Cyanocobalamin) 是一种水溶性维生素,对大脑和神经系统的正常运作,及血液形成起到关键作用。 |
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J Mol Model, 2022, 28(6):153
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Cell Chem Biol, 2021, S2451-9456(21)00213-0
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Gastroenterology, 2019, 10.1053/j
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S1744 |
Nicotinic Acid
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Nicotinic Acid是一种水溶性维生素,属于维生素B族。 |
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Gut Microbes, 2022, 14(1):2096989
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Sci Adv, 2021, 7(30)eabf3895
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Sci Adv, 2021, 7(30)eabf3895
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S4063 |
cholecalciferol (Vitamin D3)
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Cholecalciferol (Vitamin D3, Cholecalciferol, Colecalciferol)是维生素D的一种, 结合并激活H305F/H397Y突变型维生素D 受体(VDR),EC50 为300 nM. |
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FEBS Open Bio, 2023, 13(9):1789-1806
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Cells, 2021, 10(8)2149
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Oncogene, 2020, 10.1038/s41388-020-01453-2
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S4605 |
Folic acid
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Folic acid (Folacin, Vitamin B9, Vitamin M, Pteroylglutamic acid, Folate),一种维生素B,在细胞分裂和氨基酸、核苷酸合成中起到重要作用。 |
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Redox Biol, 2023, 10.1016/j.redox.2023.102939
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Oxid Med Cell Longev, 2022, 2022:1486157
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J Mol Model, 2022, 28(6):153
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S4245 |
Sodium ascorbate
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Sodium ascorbate(Sodium Vitamin C)作为抗氧化剂和酸度调节剂,在消除慢性和急性感染方面发挥重要作用。 |
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Clin Transl Med, 2021, 11(7):e495
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J Am Soc Nephrol, 2020, 31(1):54-65
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Biochem Biophys Res Commun, 2018, 503(2):420-427
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S3130 |
Biotin (Vitamin B7)
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Biotin (Vitamin B7)是一种维生素B,对于细胞生长,脂肪酸生成以及脂肪和氨基酸代谢是必需的。Biotin与组蛋白中不同的赖氨酸残基共价连接,影响染色质结构并介导基因调控。 |
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PLoS Pathog, 2020, 16;16(3):e1008341
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J Biol Chem, 2018, 293(24):9461-9472
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S6681 |
Paricalcitol
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Paricalcitol是一种选择性的vitamin D receptor激动剂。 Paricalcitol抑制甲状旁腺激素mRNA表达并抑制甲状旁腺细胞增殖。Pariccitol用于治疗慢性肾脏疾病的继发性甲状旁腺功能亢进。 |
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Redox Biol, 2024, 70:103062
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Front Cardiovasc Med, 2022, 9:855181
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Eur J Neurosci, 2022, 10.1111/ejn.15833
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S2540 |
Riboflavin
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Riboflavin (Vitamin B2, E101) 是一种易被吸收的微量营养素,对维持人和其他动物的健康起到了关键作用。 |
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J Mol Model, 2022, 28(6):153
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S3211 |
Thiamine HCl (Vitamin B1)
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Thiamine HCl (Vitamin B1) 是一种水溶性的复合维生素B,它的磷酸盐衍生物参与多个细胞内过程。 |
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Signal Transduct Target Ther, 2024, 9(1):86
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Nat Commun, 2023, 10.1038/s41467-023-43261-8
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S5082 |
Vitamin K2 (Menaquinone)
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Vitamin K2 (Menaquinone)是一种十分重要的脂溶性维生素,在保护心脏和大脑、构建强壮的骨骼过程中发挥重要作用。 |
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Aging (Albany NY), 2023, 15(24):14764-14790
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Int J Stem Cells, 2020, 10.15283/ijsc20152
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S5474 |
Dibenzoyl Thiamine
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Dibenzoyl Thiamine (Bentiamine, O,S-Dibenzoylthiamine), a lipophilic derivative of vitamin B (thiamine), is a kind of food additive that can be rapidly absorbed into the body and converted to thiamine. |
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J Mol Model, 2022, 28(6):153
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S4144 |
Amprolium HCl
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Amprolium HCl是Vitamin B1的拮抗剂,通过抑制Vitamin B1的吸收而阻止碳水化合物的合成。 |
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Signal Transduct Target Ther, 2024, 9(1):86
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Nat Commun, 2023, 10.1038/s41467-023-43261-8
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S6102 |
Thiamine pyrophosphate hydrochloride
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Thiamine pyrophosphate hydrochloride (cocarboxylase)是一种硫胺素衍生物,由硫胺素二磷酸激酶合成。它是很多原核生物酶的辅酶,参与调节基础代谢。 |
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J Mol Model, 2022, 28(6):153
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S2297 |
Ergosterol
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Ergosterol是甾醇,是vitamin D2的生物前体(一种维生素原)。 |
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J Mol Model, 2022, 28(6):153
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S6614 |
Fursultiamine
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Fursultiamine (Thiamine tetrahydrofurfuryl disulfide)是一种营养补充品和维他命B1衍生物,具有潜在的抗肿瘤活性。 |
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J Mol Model, 2022, 28(6):153
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S4083 |
Vitamin A Acetate
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Vitamin A Acetate (Retinyl, Retinol)属脂溶性维生素,包括视黄醇、视黄醛、视黄酸,和植物中的胡萝卜素。其中β-胡萝卜素是最重要的。 |
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Neural Regen Res, 2024, 19(1):205-211
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Stem Cells Transl Med, 2017, 6(9):1803-1814
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S5558 |
D-Pantothenate Sodium
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D-Pantothenate Sodium, the sodium salt of D-pantothenate, is a derivative of vitamin B5 which is an an essential nutrient and plays important roles in the oxidation of fats and carbohydrates and certain amino acids. |
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Front Cell Dev Biol, 2019, 7:204
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S1921 |
Phenindione
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Phenindione (Rectadione, phenylindandione) 是一种抗凝血剂,作为Vitamin K拮抗剂。 |
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S1767 |
Beta Carotene
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Beta Carotene(β-Carotene)是一种有机化合物,为萜类化合物,是维生素A的前体(非活性形式)。此产品溶解度不佳,动物实验可用,细胞实验请谨慎选择! |
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S4486 |
Thiamine monochloride
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Thiamine (Vitamin B1) monochloride 是一种必不可少的维生素 vitamin,它在摄取食物的细胞能量生产中起着重要作用,并能增强正常的神经元活性。 |
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S5592 |
Vitamin A (Retinol)
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Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs. |
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Stem Cells Transl Med, 2017, 6(9):1803-1814
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S4503 |
Calcium D-Panthotenate
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Calcium D-Panthotenate (D-Pantothenic Acid Calcium)也被称为vitamin B5 Calcium,是一种水溶性维生素,是许多动物的必需营养素。
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S5568 |
Tocofersolan
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Tocofersolan (Tocophersolan) is a synthetic water-soluble version of vitamin E that is used in treatment of vitamin E deficiency. |
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S5668 |
Chlorindione
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Chlorindione is an antagonist of vitamin K. |
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S5386 |
7-Dehydrocholesterol
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7-Dehydrocholesterol (7-DHC, Provitamin D3) is the direct precursor of free cholesterol in the cholesterol biosynthetic pathway in mammalian tissues and also a biosynthetic precursor to vitamin D3. |
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S4126 |
Retinyl (Vitamin A) Palmitate
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Retinyl (Vitamin A) Palmitate是一种更稳定的,将必需营养素维生素A加入到棕榈酸的合成物。
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S5203 |
Sulbutiamine
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Sulbutiamine (Bisibutiamine, Vitaberin, Youvitan) is a synthetic derivative of thiamine (vitamin B1), belonging to a class of supplements shown to help improve memory, learning capacity, decision-making, concentration, and focus. |
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S5955 |
Thiamine nitrate
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Thiamine (Vitamin B1) nitrate 是一种必需的维生素,它在细胞从摄入食物中产生能量时发挥重要作用,并可增强正常的神经元活性。 |
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S4871 |
Pyridoxal 5-phosphate monohydrate
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Pyridoxal 5-phosphate monohydrate是一种活性的维他命B6代谢物,是很多氨基酸代谢反应的辅因子。 |
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S4695 |
D panthenol
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D panthenol (Dexpanthenol, D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol)是D-pantothenic acid的酒精类似物,是胆碱能剂。 |
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S3681 |
Vitamin E Acetate
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Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant. |
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S4698 |
Vitamin K1
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Vitamin K1 (Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione), made by plants, is a major type of dietary vitamin K, which is well-known for its role in blood clotting. Vitamin K1 is directly involved in photosynthesis. |
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E4913New |
Calcifediol monohydrate
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Calcifediol monohydrate(25-hydroxy Vitamin D3 monohydrate)是一种有效的维生素 D 受体 (VDR) 配体和 VD 补充剂。它可作为维生素 D 受体 (VDR) 的抑制剂。骨化二醇是维生素 D 内分泌系统 (VDES) 的激素原,在肝脏中羟基化产生活性形式骨化三醇。骨化二醇可快速提高血清 VD 水平。 |
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S4779 |
Menadiol Diacetate
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Menadiol Diacetate (Vitamin K4, Acetomenaphthone, Kapilin) is a synthetic hydrophilic menadione compound, which is clinically used as hemostasis medicine. It induces caspase-3-related apoptosis pathway via mitochondrial dysfunction and DNA fragmentation. |
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S3113 |
Pyridoxine HCl
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Pyridoxine HCl (Vitamin B6,Pyridoxol hydrochloride)是维生素B6的一种形式。有助于维持钠和钾的平衡, 同时会促进红细胞生成。通过降低同型半胱氨酸的形成有助于心血管健康。Pyridoxine可能会帮助女性体内激素变化的平衡维持并有助于免疫系统。缺乏pyridoxine 可能会引起贫血,神经损伤,皮肤疾病以及口腔褥疮。 |
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S3171New |
Amprolium
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Amprolium(Amprol) 是硫胺素(维生素 B1)的拮抗剂,可显著影响细胞内硫胺素的运输和利用。 |
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S4994 |
Methylcobalamin
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Methylcobalamin (Mecobalamin, Vancomin, Methycobal, Cobametin) 是维他命B12的活性形式之一,维他命B12可直接参与同型半胱氨酸代谢。它被用与治疗一些营养性疾病和其他临床疾病如阿尔茨海默症和类风湿性关节炎。 |
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S5846 |
Apocarotenal
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Apocarotenal是一种类胡萝卜素,可存在于菠菜和柑橘类水果中,是维他命A的前体。 |
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S4987 |
Inositol niacinate
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Inositol Niacinate (Inositol hexanicotinate, Myo-Inositol hexanicotinate)是烟酸(niacin)的一种形式,烟酸也被称作维他命B3,是人体必需的营养素。 |
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S3980 |
Pyridoxine
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Pyridoxine (Pyridoxol, Vitamin B6, Gravidox), also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement. It is a cofactor for both glutamic acid decarboxylase and GABA transaminase. |
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S5220 |
D-Pantethine
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Pantethine (Bis-pantethine, Pantetina, Pantomin, Pantosin)是一种天然产物,在体内由泛酸(维生素B5)通过半胱胺的加入合成,被用作一种食品添加剂,降低血胆固醇和三酸甘油脂。 |
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S4811 |
VitaMin U
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Vitamin U (Methylmethioninesulfonium Chloride, Cabagin-U, Smethylmethionine) is a vitamin found in green vegetables. It is used in the treatment of peptic ulcers, colitis, and gastritis and has an effect on secretory, acid-forming, and enzymatic functions of the intestinal tract. |
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S5311 |
Pyridoxal phosphate
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Pyridoxal phosphate (Pyridoxal 5'-phosphate, PAL-P, PLP, Vitamin B6), the active form of vitamin B6, acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids. |
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J Immunother Cancer, 2024, 12(9)e009603
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