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Cholinesterase (ChE)

Cholinesterase (ChE)产品

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  • Cholinesterase (ChE)抑制剂 (36)
  • Cholinesterase (ChE)激活剂 (1)
  • Cholinesterase (ChE)拮抗剂 (3)
  • Cholinesterase (ChE)激动剂 (2)
  • Cholinesterase (ChE)调节剂 (1)
目录号 产品名 产品描述 文献引用 实验数据
S2462 Donepezil HCl Donepezil HCl 是一种特异性的，有效的AChE抑制剂，作用于bAChE和hAChE，IC50分别为8.12 nM和11.6 nM。此产品不溶于PBS，请勿用PBS溶解给药。
Sci Adv, 2025, 11(14):eads7191
Theranostics, 2023, 13(6):1826-1842
J Cell Physiol, 2023, 10.1002/jcp.31057
S3809 Imperatorin Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.
Pharmaceuticals (Basel), 2023, 10.3390/ph16111595
Metabolites, 2022, 13(1)3
Adv Sci (Weinh), 2020, 7(16):2000925
S1890 Nizatidine Nizatidine是一种组胺H2受体拮抗剂，作用于AChE，IC50为6.7 nM。
Gastroenterology, 2022, 162(4):1210-1225
Calcif Tissue Int, 2021, 109(6):696-705
bioRxiv, 2021, 10.1101/2021.04.29.441931
S5073 Donepezil Donepezil (Aricept, Donepezilo)是一种有效的、可逆的、特异的和非竞争性acetylcholinesterase (AChE)抑制剂，用于治疗轻度至中度痴呆。
Cell Biosci, 2024, 14(1):146
Theranostics, 2023, 13(6):1826-1842
Front Bioeng Biotechnol, 2022, 10:855755
S2087 Rivastigmine Tartrate Rivastigmine Tartrate (ENA 713) 是一种胆碱酯酶抑制剂，IC50为5.5 μM，作为副交感神经或胆碱能剂，用于治疗轻度至中度阿尔茨海默病。
J Cell Physiol, 2023, 10.1002/jcp.31057
Mol Psychiatry, 2018, 23(3):767-776
S2251 (-)-Huperzine A (HupA) (-)-Huperzine A (HupA)是一种有效的，高度特异性的，可逆acetylcholinesterase (AChE)（乙酰胆碱酯酶）抑制剂，Ki为7 nM，作用于G4 AChE比作用于G1 AChE选择性高200倍。Phase 4。
Acta Pharmacol Sin, 2019, 10.1038/s41401-018-0206-4
S1339 Galanthamine HBr Galanthamine HBr是一种AChE抑制剂，IC50为0.35 μM，比作用于丁酰胆碱酯酶选择性高50倍。
J Cell Physiol, 2023, 10.1002/jcp.31057
S1608 Pyridostigmine Bromide Pyridostigmine Bromide 是一种拟副交感神经的和可逆的胆碱酯酶抑制剂。
J Immunother Cancer, 2024, 12(11)e009805
J Am Heart Assoc, 2014, 3(3):e000804
S2490 Neostigmine Bromide Neostigmine Bromide 是一种可逆的胆碱酯酶抑制剂。
Am J Physiol Gastrointest Liver Physiol, 2016, 310(3):G181-92
S5900 Edrophonium chloride Edrophonium chloride是edrophonium的氯盐形式。Edrophonium是一种快速起效、短效、易可逆的acetylcholinesterase (乙酰胆碱酯酶)抑制剂。
Front Mol Biosci, 2024, 11:1423351
Int J Mol Sci, 2023, 10.3390/ijms242115535
S9290 Linarin Linarin (Acaciin, Buddleoside, Acacetin-7-O-rutinoside), a natural flavonoid cpompound, has pharmacological effects, including anti-inflammatory, neuro-protective, cardioprotective and antioxidative effects.
Front Pharmacol, 2020, 11:582520
S4687 Rivastigmine Rivastigmine (SDZ-ENA 713, Exelon) 是一种胆碱酯酶的抑制剂，IC50为5.5 μM。它抑制乙酰胆碱酯酶（IC50=4.15 µM）和丁酰胆碱酯酶（IC50=37 nM）。
Front Mol Biosci, 2024, 11:1423351
Nature, 2018, 560(7718):372-376
S3866 Galanthamine Galanthamine (Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is a phenanthrene alkaloid and a reversible, competitive acetylcholinesterase inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. It is studied as a treatment for Alzheimer's disease and other central nervous system disorders.
S3235 Sinapine Sinapine 是一种从十字花科物种的种子中分离出来的生物碱，具有抗氧化、抗肿瘤和放射防护的作用。Sinapine 通过下调 P-glycoprotein 来抑制Caco-2细胞的增殖。
Gene, 2022, 827:146460
S9178 Sinapine thiocyanate Sinapine thiocyanate is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities.
Gene, 2022, 827:146460
S4575 Pralidoxime chloride Pralidoxime chloride (2-PAM)是有机磷农药和一些化学制品的解毒剂。是AChE的重新激活剂。
E7226 Pirimiphos-methyl Pirimiphos-methyl 是一种快速作用的有机磷杀虫剂和杀螨剂，可抑制目标生物体中的乙酰胆碱酯酶 (AChE)。Pirimiphos-methyl 经常在农业谷物的储存过程中用于预防和控制甲虫，鼻子甲虫，飞蛾和埃氏小球藻。
S0924 Pteryxin Pteryxin ((+)-Pteryxin) 是一种在 Apiaceae 伞形科中发现的二氢吡喃香豆素衍生物，也是一种有效的 butyrylcholinesterase (BChE) 的抑制剂，IC50值为12.96 μg/ml。Pteryxin 可抑制LPS诱导的小鼠腹膜巨噬细胞中 nitric oxide 的产生，其IC50值为20 μM。Pteryxin 具有治疗阿尔茨海默氏病 (AD) 的潜力。
S9219 Huperzine B Huperzine B, a natural alkaloid existed in Lycopodium plants, is a novel acetylcholinesterase inhibitor and has neuroprotective effects.
S5886 Hodostin Hodostin (Neostigmine methyl sulfate, Syntostigmin, Neostigmeth) 是acetylcholinesterase (AChE)的可逆性抑制剂，不能穿透血脑屏障，用于治疗重症肌无力。
S3246 Picfeltarraenin IB Picfeltarraenin IB 是从 Picriafel-terrae 中分离出的葫芦素糖苷，是 acetylcholinesterase (AChE) 的抑制剂。Picfeltarraenin IB 可用于治疗疱疹感染，癌症和炎症。
S5663 Minaprine dihydrochloride Minaprine dihydrochloride is hydrochloride salt form of Minaprine, which acts as a reversible inhibitor of MAO-A in rats and weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.
S9252 Corydaline Corydaline is a bioactive alkaloid with various anti-acetylcholinesterase, anti-allergic, and anti-nociceptive activities found in the medicinal herb Corydalis Tubers.
S5665 Drofenine Hydrochloride Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.
S9257 Acetylshikonin Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma. It is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s.
S9260 Nodakenin Nodakenin ((+)-Marmesinin), a coumarin compound, acts as an AChE inhibitor that inhibits AChE activity in a dosedependent manner with an IC50 value of 84.7 μM.
S3835 Loganin Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
S4619 Itopride hydrochloride Itopride hydrochloride (Ganaton, HSR803) 是一种AChE抑制剂。其IC50为2.04 +/- 0.27 μM。
S9463 Demecarium Bromide Demecarium Bromide 是一种抗胆碱酯酶药物，是单胺氧化酶 (MAO) 的抑制剂。 它会引起长期瞳孔缩小，并降低血压正常的比格犬和患有遗传性青光眼的比格犬的眼睛的眼压 (IOP)。
S3701 Benactyzine hydrochloride Benactyzine hydrochloride是中枢性毒蕈碱受体拮抗剂。在抑郁症和相关焦虑的治疗中，它被用作抗抑郁剂。
S4972 Choline Glycerophosphate Choline Glycerophosphate (Glycerophosphorylcholine) 是胆碱衍生物，是胞浆中两种主要的胆碱储存形式之一。
S3639 Tacrine hydrochloride hydrate Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) 是胆碱酯酶（cholinesterase）抑制剂，可对抗骨骼肌松弛药的作用，可作为呼吸兴奋剂并用于治疗阿兹海默病和其他中枢神经系统障碍。它也是组胺N-甲基转移酶（histamine N-methyltransferase）抑制剂。
S4072 Decamethonium Bromide Decamethonium Bromide是一种烟碱AChR部分激动剂和神经肌肉阻断剂。
S3769 Palmatine Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.
Eur J Pharmacol, 2024, 967:176395
S9069 Jatrorrhizine chloride Jatrorrhizine chloride (Neprotine, Yatrorhizine) is the hydrochloride salt form of jatrorrhizine, which is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
S9386 Polygalacic acid Polygalacic acid 是从远志属植物（Polygala paenea L.）分离出的三萜类四羟酸。Polygalacic acid (0-100μM; 24h) 可以显著降低 MMP-3、MMP-9、MMP-13 和 COX-2 的mRNA表达，这些因子的表达由IL-1β诱导可显著增加，并呈现出剂量依赖性。
S9085 Corynoline Corynoline is one of the major active components of many ethnopharmacological plants and exhibits anti-tumor, anti-inflammatory and hepatoprotective activities, etc.
S9087 Tenuifolin Tenuifolin, a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.
CNS Neurosci Ther, 2025, 31(8):e70588
E7361 (±)-Huperzine A (±)-Huperzine A 是传统中草药中提取的活性石松属生物碱，是可逆的乙酰胆碱酯酶（ACE）抑制剂，在中国被广泛的运用于阿尔茨海默病。
S4804 1-Naphthyl acetate 1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages.
S3881 Scopoletin Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.
Biochem Biophys Rep, 2025, 42:102021
S3884 Jatrorrhizine Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
S3704 4-Methylbenzylidene camphor 4-Methylbenzylidene camphor (Enzacamene, 4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation.
S9108 Timosaponin A3 Timosaponin A3 (Filiferin B, AneMarsaponin A3), one of the major steroidal saponin components isolated from Anemarrhena asphodeloides, displays promising pharmacological activity in improving learning, memory, and antineoplastic activity.
S5085 Azamethiphos Azamethiphos是有机磷酸酯杀虫剂，用于治疗养殖大马哈鱼的海虱感染。
E0905 N-p-trans-Coumaroyltyramine

N-p-trans-Coumaroyltyramine is an alpha-glucosidase inhibitor.
S3904 Isoimperatorin Isoimperatorin, a natural furanocoumarin that can be isolated from a variety of plant parts, has analgesic, antimicrobial, vascular relaxing and anticancer activities.
S9138 Picfeltarraenin IA Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system.
S9152 Epiberberine Epiberberine, a natural protoberberine alkaloid, is a potent inhibitor against both ureases with IC50 values of 3.0±0.01μM for HPU (ureases from Helicobacter pylori) and 2.3±0.01μM for JBU (ureases from jack bean).
S9510 Protriptyline hydrochloride Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline. Protriptyline is a tricyclic secondary amine with antidepressant property which acts by inhibition of serotonin and norepinephrine reuptake.
S4521 DEET DEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) 是一种常见的杀虫剂的活性成分。
S4838 Acotiamide hydrochloride Acotiamide Hydrochloride (YM-443, Z-338)是acotiamide的盐酸形式，acotiamide是一种肠蠕动促进剂。它是一种新型的、具有口服活性的、选择性的AChE抑制剂。
S5868 DL-Menthol DL-Menthol是D-和L-menthol的外消旋混合物。Menthol是一种共价有机化合物，可通过有机反应合成或从薄荷油中提取。
E5819New Clozapine N-oxide dihydrochloride Clozapine N-oxide dihydrochloride 是氯氮平的主要代谢产物。它可作为人类毒蕈碱受体 DREADD 的激动剂，对 M1 DREADD 的 pEC50 为 8.31。
S2462 Donepezil HCl Donepezil HCl 是一种特异性的，有效的AChE抑制剂，作用于bAChE和hAChE，IC50分别为8.12 nM和11.6 nM。此产品不溶于PBS，请勿用PBS溶解给药。
Sci Adv, 2025, 11(14):eads7191
Theranostics, 2023, 13(6):1826-1842
J Cell Physiol, 2023, 10.1002/jcp.31057
S5073 Donepezil Donepezil (Aricept, Donepezilo)是一种有效的、可逆的、特异的和非竞争性acetylcholinesterase (AChE)抑制剂，用于治疗轻度至中度痴呆。
Cell Biosci, 2024, 14(1):146
Theranostics, 2023, 13(6):1826-1842
Front Bioeng Biotechnol, 2022, 10:855755
S2087 Rivastigmine Tartrate Rivastigmine Tartrate (ENA 713) 是一种胆碱酯酶抑制剂，IC50为5.5 μM，作为副交感神经或胆碱能剂，用于治疗轻度至中度阿尔茨海默病。
J Cell Physiol, 2023, 10.1002/jcp.31057
Mol Psychiatry, 2018, 23(3):767-776
S2251 (-)-Huperzine A (HupA) (-)-Huperzine A (HupA)是一种有效的，高度特异性的，可逆acetylcholinesterase (AChE)（乙酰胆碱酯酶）抑制剂，Ki为7 nM，作用于G4 AChE比作用于G1 AChE选择性高200倍。Phase 4。
Acta Pharmacol Sin, 2019, 10.1038/s41401-018-0206-4
S1339 Galanthamine HBr Galanthamine HBr是一种AChE抑制剂，IC50为0.35 μM，比作用于丁酰胆碱酯酶选择性高50倍。
J Cell Physiol, 2023, 10.1002/jcp.31057
S1608 Pyridostigmine Bromide Pyridostigmine Bromide 是一种拟副交感神经的和可逆的胆碱酯酶抑制剂。
J Immunother Cancer, 2024, 12(11)e009805
J Am Heart Assoc, 2014, 3(3):e000804
S2490 Neostigmine Bromide Neostigmine Bromide 是一种可逆的胆碱酯酶抑制剂。
Am J Physiol Gastrointest Liver Physiol, 2016, 310(3):G181-92
S5900 Edrophonium chloride Edrophonium chloride是edrophonium的氯盐形式。Edrophonium是一种快速起效、短效、易可逆的acetylcholinesterase (乙酰胆碱酯酶)抑制剂。
Front Mol Biosci, 2024, 11:1423351
Int J Mol Sci, 2023, 10.3390/ijms242115535
S4687 Rivastigmine Rivastigmine (SDZ-ENA 713, Exelon) 是一种胆碱酯酶的抑制剂，IC50为5.5 μM。它抑制乙酰胆碱酯酶（IC50=4.15 µM）和丁酰胆碱酯酶（IC50=37 nM）。
Front Mol Biosci, 2024, 11:1423351
Nature, 2018, 560(7718):372-376
S3866 Galanthamine Galanthamine (Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is a phenanthrene alkaloid and a reversible, competitive acetylcholinesterase inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. It is studied as a treatment for Alzheimer's disease and other central nervous system disorders.
S3235 Sinapine Sinapine 是一种从十字花科物种的种子中分离出来的生物碱，具有抗氧化、抗肿瘤和放射防护的作用。Sinapine 通过下调 P-glycoprotein 来抑制Caco-2细胞的增殖。
Gene, 2022, 827:146460
S0924 Pteryxin Pteryxin ((+)-Pteryxin) 是一种在 Apiaceae 伞形科中发现的二氢吡喃香豆素衍生物，也是一种有效的 butyrylcholinesterase (BChE) 的抑制剂，IC50值为12.96 μg/ml。Pteryxin 可抑制LPS诱导的小鼠腹膜巨噬细胞中 nitric oxide 的产生，其IC50值为20 μM。Pteryxin 具有治疗阿尔茨海默氏病 (AD) 的潜力。
S9219 Huperzine B Huperzine B, a natural alkaloid existed in Lycopodium plants, is a novel acetylcholinesterase inhibitor and has neuroprotective effects.
S5886 Hodostin Hodostin (Neostigmine methyl sulfate, Syntostigmin, Neostigmeth) 是acetylcholinesterase (AChE)的可逆性抑制剂，不能穿透血脑屏障，用于治疗重症肌无力。
S3246 Picfeltarraenin IB Picfeltarraenin IB 是从 Picriafel-terrae 中分离出的葫芦素糖苷，是 acetylcholinesterase (AChE) 的抑制剂。Picfeltarraenin IB 可用于治疗疱疹感染，癌症和炎症。
S5663 Minaprine dihydrochloride Minaprine dihydrochloride is hydrochloride salt form of Minaprine, which acts as a reversible inhibitor of MAO-A in rats and weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.
S9252 Corydaline Corydaline is a bioactive alkaloid with various anti-acetylcholinesterase, anti-allergic, and anti-nociceptive activities found in the medicinal herb Corydalis Tubers.
S5665 Drofenine Hydrochloride Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.
S9257 Acetylshikonin Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma. It is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s.
S9260 Nodakenin Nodakenin ((+)-Marmesinin), a coumarin compound, acts as an AChE inhibitor that inhibits AChE activity in a dosedependent manner with an IC50 value of 84.7 μM.
S3835 Loganin Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
S4619 Itopride hydrochloride Itopride hydrochloride (Ganaton, HSR803) 是一种AChE抑制剂。其IC50为2.04 +/- 0.27 μM。
S9463 Demecarium Bromide Demecarium Bromide 是一种抗胆碱酯酶药物，是单胺氧化酶 (MAO) 的抑制剂。 它会引起长期瞳孔缩小，并降低血压正常的比格犬和患有遗传性青光眼的比格犬的眼睛的眼压 (IOP)。
S3639 Tacrine hydrochloride hydrate Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) 是胆碱酯酶（cholinesterase）抑制剂，可对抗骨骼肌松弛药的作用，可作为呼吸兴奋剂并用于治疗阿兹海默病和其他中枢神经系统障碍。它也是组胺N-甲基转移酶（histamine N-methyltransferase）抑制剂。
S3769 Palmatine Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.
Eur J Pharmacol, 2024, 967:176395
S9069 Jatrorrhizine chloride Jatrorrhizine chloride (Neprotine, Yatrorhizine) is the hydrochloride salt form of jatrorrhizine, which is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
S9386 Polygalacic acid Polygalacic acid 是从远志属植物（Polygala paenea L.）分离出的三萜类四羟酸。Polygalacic acid (0-100μM; 24h) 可以显著降低 MMP-3、MMP-9、MMP-13 和 COX-2 的mRNA表达，这些因子的表达由IL-1β诱导可显著增加，并呈现出剂量依赖性。
S9087 Tenuifolin Tenuifolin, a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.
CNS Neurosci Ther, 2025, 31(8):e70588
E7361 (±)-Huperzine A (±)-Huperzine A 是传统中草药中提取的活性石松属生物碱，是可逆的乙酰胆碱酯酶（ACE）抑制剂，在中国被广泛的运用于阿尔茨海默病。
S3884 Jatrorrhizine Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
E0905 N-p-trans-Coumaroyltyramine

N-p-trans-Coumaroyltyramine is an alpha-glucosidase inhibitor.
S3904 Isoimperatorin Isoimperatorin, a natural furanocoumarin that can be isolated from a variety of plant parts, has analgesic, antimicrobial, vascular relaxing and anticancer activities.
S9138 Picfeltarraenin IA Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system.
S9152 Epiberberine Epiberberine, a natural protoberberine alkaloid, is a potent inhibitor against both ureases with IC50 values of 3.0±0.01μM for HPU (ureases from Helicobacter pylori) and 2.3±0.01μM for JBU (ureases from jack bean).
S9510 Protriptyline hydrochloride Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline. Protriptyline is a tricyclic secondary amine with antidepressant property which acts by inhibition of serotonin and norepinephrine reuptake.
S4838 Acotiamide hydrochloride Acotiamide Hydrochloride (YM-443, Z-338)是acotiamide的盐酸形式，acotiamide是一种肠蠕动促进剂。它是一种新型的、具有口服活性的、选择性的AChE抑制剂。
S4575 Pralidoxime chloride Pralidoxime chloride (2-PAM)是有机磷农药和一些化学制品的解毒剂。是AChE的重新激活剂。
S3809 Imperatorin Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.
Pharmaceuticals (Basel), 2023, 10.3390/ph16111595
Metabolites, 2022, 13(1)3
Adv Sci (Weinh), 2020, 7(16):2000925
S1890 Nizatidine Nizatidine是一种组胺H2受体拮抗剂，作用于AChE，IC50为6.7 nM。
Gastroenterology, 2022, 162(4):1210-1225
Calcif Tissue Int, 2021, 109(6):696-705
bioRxiv, 2021, 10.1101/2021.04.29.441931
S3701 Benactyzine hydrochloride Benactyzine hydrochloride是中枢性毒蕈碱受体拮抗剂。在抑郁症和相关焦虑的治疗中，它被用作抗抑郁剂。
S4072 Decamethonium Bromide Decamethonium Bromide是一种烟碱AChR部分激动剂和神经肌肉阻断剂。
E5819New Clozapine N-oxide dihydrochloride Clozapine N-oxide dihydrochloride 是氯氮平的主要代谢产物。它可作为人类毒蕈碱受体 DREADD 的激动剂，对 M1 DREADD 的 pEC50 为 8.31。
S5868 DL-Menthol DL-Menthol是D-和L-menthol的外消旋混合物。Menthol是一种共价有机化合物，可通过有机反应合成或从薄荷油中提取。
E5819New Clozapine N-oxide dihydrochloride Clozapine N-oxide dihydrochloride 是氯氮平的主要代谢产物。它可作为人类毒蕈碱受体 DREADD 的激动剂，对 M1 DREADD 的 pEC50 为 8.31。
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