MT Receptor

MT Receptor产品

• 所有产品(4)
• MT Receptor拮抗剂 (1)
• MT Receptor激动剂 (3)
• 新MT Receptor产品

目录号	产品名	产品描述	文献引用	实验数据
S1204	Melatonin	Melatonin是一种 MT receptor 激动剂激素, 用作膳食补充品。Melatonin 是一种选择性的 ATF-6 的抑制剂并可下调 COX-2。Melatonin 可增强线粒体自噬并调节凋亡和自噬的稳态。	Heliyon, 2024, 10(18):e38098 Heliyon, 2024, 10(11):e32571 Ecotoxicol Environ Saf, 2023, 255:114719
S1259	Ramelteon	Ramelteon (TAK-375) 是一种新型的的Melatonin受体激动剂，作用于人MT1和MT2受体及小鸡前脑Melatonin受体，Ki值分别为14 pM， 112 pM和23.1 pM。	Aging Cell, 2021, e13375 Cell Cycle, 2021, 20(12):1195-1208 Plant Cell Physiol, 2020, 10.1093/pcp/pcaa018
S3584	Luzindole	Luzindole (N-0774, N-acetyl-2-benzyltryptamine) 是一种选择性 褪黑激素受体(melatonin receptor) 拮抗剂，对MT1的Ki值为179 nM，对MT2的Ki值为7.3 nM。	Aging Cell, 2021, e13375 Int Immunopharmacol, 2021, 96:107787
S4281	Tasimelteon	Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).	Cells, 2022, 11(21)3467
S3584	Luzindole	Luzindole (N-0774, N-acetyl-2-benzyltryptamine) 是一种选择性 褪黑激素受体(melatonin receptor) 拮抗剂，对MT1的Ki值为179 nM，对MT2的Ki值为7.3 nM。	Aging Cell, 2021, e13375 Int Immunopharmacol, 2021, 96:107787
S1204	Melatonin	Melatonin是一种 MT receptor 激动剂激素, 用作膳食补充品。Melatonin 是一种选择性的 ATF-6 的抑制剂并可下调 COX-2。Melatonin 可增强线粒体自噬并调节凋亡和自噬的稳态。	Heliyon, 2024, 10(18):e38098 Heliyon, 2024, 10(11):e32571 Ecotoxicol Environ Saf, 2023, 255:114719
S1259	Ramelteon	Ramelteon (TAK-375) 是一种新型的的Melatonin受体激动剂，作用于人MT1和MT2受体及小鸡前脑Melatonin受体，Ki值分别为14 pM， 112 pM和23.1 pM。	Aging Cell, 2021, e13375 Cell Cycle, 2021, 20(12):1195-1208 Plant Cell Physiol, 2020, 10.1093/pcp/pcaa018
S4281	Tasimelteon	Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).	Cells, 2022, 11(21)3467