- 5-HT1
- 5-HT2
- 5-HT3
- 5-HT4
- 5-HT6
- 5-HT7
- 5-HT5
5-HT5 拮抗剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S1283 | Asenapine maleate | Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder. | Pan | 5-HT5A, pKi: 8.84 |
| S1615 | Risperidone | Risperidone (R-64766) is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder. | Pan | 5-HT5A, Ki: 206 nM; 5-HT5A, Ki: 206 nM |
