Caspase-1
Caspase-3
Caspase-8
Caspase-9
Caspase-4
Capase-7
Caspase-2
Caspase-5
Caspase-6
Caspase-10
Caspase-7

Caspase-2 抑制剂 | 激活剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S7901	Ac-DEVD-CHO	Ac-DEVD-CHO (Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO) is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2.	Pan	caspase-2, Ki: 1.71 μM
S4353	Terfenadine	Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.	Pan